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Marcus Clauss 《Journal of Exotic Pet Medicine》2012,21(1):80-86
The recommended diets of pet rabbits and herbivorous rodents are often based on hays (dried forages) as the staple diet item. The rationale for this recommendation is a combination of logistical factors (i.e., hays are more readily available than a constant supply of fresh forage) and health concerns (i.e., using hays rather than fruits, nonleafy vegetables, and grain products apparently circumvents several health problems). Offering a variety of hays is a feeding concept that has so far received little attention. The choice of hays should be based primarily on a hygienic evaluation. Although hays have to be of impeccable hygienic quality, they need not necessarily be of high nutritive quality. A high proportion of stems and high-fiber material may be adequate for the maintenance of herbivores, and hays of higher nutritional quality can be used as dietary supplements in animals with increased energy requirements. Educating pet owners about the use of multiple hay combinations and the appreciation of the nutritive variety of hays may represent an opportunity for channeling interest and engagement in their animal while concurrently providing a preventive health measure. 相似文献
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Mary F. Thompson BVSc ; J. Catharine Scott-Moncrieff MA MS Vet MB Dip ACVIM; Daniel F. Hogan DVM Dip ACVIM 《Journal of Veterinary Emergency and Critical Care》2001,11(2):111-121
Objective: To review the thrombolytic agents most commonly used in humans, their mechanisms of action, potential uses, adverse effects, and reports of their use in dogs and cats.
Human data synthesis: Thrombolytic agents avaliable in human medicine include streptokinase, urokinase, tissueplasminogen activator (t-PA), single-chain urokinase plasma activator (scu-PA) and anisoylated plasminogen-strep-tokinase activator complex (APSAC). These agents were originally used for the management of proximal deep vein thrombosis and severe pulmonary embolism but more recently, use of these drugs has been extended to include the treatment of acute peripheral arterial disease, cerebrovascular disease (stroke) and acute coronary thrombosis. The most predictable side effect associated with the use of thrombolytic therapy is hemorrhage.
Veterinary data synthesis: Clinical experience with thrombolytic agents in small animals is limited to streptokinase and t-PA. It is possible, that as in humans, canine and feline patients with PTE and right ventricular dysfunction may benefit from thrombolytic therapy but there are no veterinary studies to support this theory to date. Successful use of streptokinase has been documented in a small number of canine patients with systemic thromboembolism.63 Thrombolytic therapy is relatively efficacious in cats with aortic thromboemboli but is associated with a high mortality rate. 59,60,64 With regard to use of t-PA in veterinary medicine, the small number of animals treated with varying protocols makes it impossible to provide safe and effective dose recommendations at this time.
Conclusions: Future goals for thrombolytic therapy in veterinary medicine include determination of more specific clinical indications, as well as design of effective protocols that minimize mortality and morbidity. 相似文献
Human data synthesis: Thrombolytic agents avaliable in human medicine include streptokinase, urokinase, tissueplasminogen activator (t-PA), single-chain urokinase plasma activator (scu-PA) and anisoylated plasminogen-strep-tokinase activator complex (APSAC). These agents were originally used for the management of proximal deep vein thrombosis and severe pulmonary embolism but more recently, use of these drugs has been extended to include the treatment of acute peripheral arterial disease, cerebrovascular disease (stroke) and acute coronary thrombosis. The most predictable side effect associated with the use of thrombolytic therapy is hemorrhage.
Veterinary data synthesis: Clinical experience with thrombolytic agents in small animals is limited to streptokinase and t-PA. It is possible, that as in humans, canine and feline patients with PTE and right ventricular dysfunction may benefit from thrombolytic therapy but there are no veterinary studies to support this theory to date. Successful use of streptokinase has been documented in a small number of canine patients with systemic thromboembolism.
Conclusions: Future goals for thrombolytic therapy in veterinary medicine include determination of more specific clinical indications, as well as design of effective protocols that minimize mortality and morbidity. 相似文献
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