A serological comparison of 4 Japanese isolates of porcine enteroviruses with the international reference strains

The reference strains of four serotypes (J6, J8, J9 and J10) of porcine enterovirus isolated in Japan were compared with the international reference strains of 11 serotypes (W1 to W11) by cross neutralization tests. No cross reactions were observed between the two groups, although there were minor one-way crosses between W10 and J10, W11 and J9, and W4 and J9. This leads to our conclusion that all 4 Japanese serotypes can be newly added to 11 international serotypes. J9 virus produced type 1 of CPE (CPE I), J6 and J8 did CPE II, and J10 did CPE III. J10 grew in Vero, HeLa cells, and the primate cells, but J6, J8 and J9 did not.     

Local interleukin-2 and interleukin-12 therapy of bovine ocular squamous cell carcinomas

Interleukin-2 and interleukin-12 have been used independently to successfully treat the induced and the spontaneous tumours in animals. This trial was done to determine if a combination of IL-2 and IL-12 in the treatment of spontaneous bovine ocular squamous cell carcinomas (BOSCC) would be more successful than IL-2 or IL-12 therapy by themselves. For this trial, we selected 25 BOSCC tumours seen on Holstein Fresian cows in Beatrice, Zimbabwe. The cows were randomly assigned to a treatment group of 5 days of IL-2 (200,000 U/day), 5 days of IL-12 (0.5 microg/day) or 5 days of IL-2 (200,000 U/day) and IL-12 (0.5 microg/day). At 20 months after treatment, the IL-2 therapy group had 63% complete regressions; the combination group had 38% complete regressions, which were significantly higher than the IL-12 group, which had 0% complete regressions at 20 months, despite having 29% complete regressions at 6 months. These results show that IL-2 therapy by itself and in combination with IL-12 is more successful than IL-12 by itself. However, combination therapy does not improve the outcome in comparison to IL-2 as a single therapy. It also proves that IL-2 is consistently successful in the therapy of BOSCC with over 60% complete regression, which corresponds to a number of other studies we have done on IL-2 therapy of BOSCC [Rutten, V.P.M.G., Klein, W.R., De Jong, W.A., Misdorp, W., Den Otter, W., Steerenberg, P.A., De Jong, W.H., Ruitenberg, E.J., 1989. Local interleukin-2 therapy in bovine ocular squamous cell carcinoma. A pilot study. Cancer Immunol. Immunother. 30, 165--169; Stewart, R.J.E., Hill, F.W.G., Masztalerz, A., Jacobs, J.J.L., Koten, J.W., Den Otter, W., 2003. Local low dose interleukin-2 therapy of bovine ocular squamous cell carcinomas in cattle in Zimbabwe, submitted for publication; Den Otter, W., Hill, F.W.G., Klein, W.R., Koten, J.W., Steerenberg, P.A., De Mulder, P.H.M., Rutten, V.P.M.G., Ruitenberg, E.J., 1993. Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma. Anticancer Res. 13, 2453-2455; Den Otter, W., Hill, F.W.G., Klein, W.R., Koten, J.W., Steerenberg, P.A., De Mulder, P.H., Rhode, C., Stewart, R., Faber, J.A., Ruitenberg, E.J., 1995. Therapy of bovine ocular squamous cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up. Cancer Immunol. Immunother. 41, 10-14].     

BOOK REVIEWS

Book reviewed in this article:
Reproductive biology in small animals: Fertility and Infertility in Dogs, Cats and other Carnivores. Edited by P. W. Concannon, G. C. W. England, J. P. Verstegen and H. A. Russell.
Practical guide to small animal nutrition: Clinical Nutrition of the Dog and Cat. By J. W. Simpson, R. S. Anderson and P. J. Markwell.
Detailed feline anatomy: Atlas of Feline Anatomy for Veterinarians. By L. C. Hudson and W. P. Hamilton.
First aid for dog owners: First Aid and Healthcare for Dogs. By C. T. P. Bell.
An overview of the feline patient: Handbook of Feline Medicine. By J. Wills and A. Wolf.
Quick guide to emergency procedures: Emergency Procedures for the Small Animal Veterinarian. By S. J. Plunkett.
Comprehensive radiology: Textbook of Veterinary Diagnostic Radiology 2nd edn. Edited by E. Thrall.
Understanding the grieving process: The Human-Animal Bond and Grief. By L. Lagoni, C. Butler and S. Hetts.     

Abstracts

BACTERIOLOGICAL: Studies on Bovine Mastitis, VII: The Serological Characters of Mastitis Streptococci. A. W. S tableforth
BACTERIOLOGICAL: The Isolation of Brucella abortus from Tonsils. C. M. C arpenter and R uth A. B oak
BACTERIOLOGICAL: Chemical Composition of the Active Principle of Tuberculin. XVI-Local Cutaneous Sensitization (Arthus Phenomenon) Produced in Normal Rabblts and Guineapigs by the Protein of Tuberculin. F lorence B. S eibert
BACTERIOLOGICAL: Recherches sur la Standardization des Sérums antigangréneux. M. W einberg , j. D avesne and A. R. P revot
BACTERIOLOGICAL: So-called Range Paralyais of the Chicken. F. D. P atterson , H. L. W ilcke , C. M urray and E. W. H enderson
BACTERIOLOGICAL: Studies on Clostridium chauvoei. D. W. H enderson
HÆMATOLOGICAL: The Hæmatology and Pathology of Hæmonchosis in Sheep. P. J. J. F ourie
HÆMATOLOGICAL: Blood Normals for Cattle: Some Pathological Values. J. A llardyce , R. H. F leming , F. L. F owler , R. H. C lark
HÆMATOLOGICAL: Blood Volume Determinations in Cattle. W. T. M iller
PARASITOLOGICAL: The Few-segmented Tapeworm of Fowls (Davainea proglottina) and its Control R. W etzel .     

BOOK REVIEWS

Book reviewed in this article:
Histological Atlas of the Laboratory Mouse . W. G. Gude and Others.
Proceedings of the Heartworm Symposium 1980 . Edited by Gilbert F. Otto.
Feline Leukemia Virus . Proceedings of the Third International Feline Virus Meeting. Editors W. D. Hardy, Jr., M. Essex, A. J. McClelland
The Horse . J. Warren Evans, Anthony Borton, Harold F. Hintz and L. Dale Van Vleck
Histological Atlas of the Laboratory Mouse . W. G. Gude and Others.     

BOOK REVIEWS

Book reviewed in this article:
Practical Small Animal Internal Medicine Edited by Michael Leib and William Monroe
Manual of Canine and Feline Gastroenterology Edited by J. W. Simpson and E. J. Hall     

Buchbesprechungen/Book Reviews

Book reviewed in this article: Streilein, J. W., D. A. Hart, J. Stein-Streilein, W. R. Duncan and R. E. Billingham: Hamster Immune Responses in Infectious and Oncologic Diseases. Geißler/Rojahn/Stein: Sammlung tierseuchenrechtlicher Vorschriften. Lundt/Schiwy: Deutsches Gesundheitsrecht. Zipfel, W.: Lebensmittelrecht. 45.     

Book Reviews

Book reviewed in this article:
Book reviewed in this article:
THE PESTICIDE MANUAL edited by C. R. Worthing & R. J. Hame
VETERINARY ANAESTHESIA by L. W. Hall & K. W. Clarke     

BOOK REVIEWS

Book reviewed in this article:
State of the art oncology for clinicians: Small Animal Clinical Oncology (2nd edition) Edited by Stephen J. Withrow and E. Gregory MacEwan. Published by W. B. Saunders
Puppies and kittens in detail: Veterinary Pediatrics: Dogs and Cats from Birth to Six Months (2nd edition). By J. D. Hoskins. Published by W. B. Saunders
Understanding canine behaviour: Think Dog: An Owner's Guide to Canine Psychology. By John Fisher. Published by Blandford Press     

Book Reviews

Book reviewed in this article:
Canine Medicine and Therapeutics 1979. Edited by E. A. Chandler, J. M. Evans, W. B. Singleton, F. G. Startup, J. B. Sutton and W. D. Tavernor.
Diagnosing Helminthiasis through Coprological Examination. By D. Thienpont, F. Rochette and O. F. J. Vanparijs.
An Atlas of Surgical Approaches to the Bones of the Dog and Cat (2nd edn). By Piermattei and Greeley.
Miller's Anatomy of the Dog (2nd edn). By H. E. Evans and G. C. Christensen.     

Book Reviews

Book reviewed in this article:
Comparative Neuropathology. J. R. M. I nnes and L. Z. S aunders , with contributions by L. V an B ogaert , R. F ankhauser , W. J. H adlow and K. V. J ubb . Academic Press, New York and London, 1962. £ 11 9s. Od.
Taschenbuch fur die Tierarxtliche Kleintier Praxis (Pocket book for Small Animal Practice). W. A. S chmidt -T reptow with contribution by D. S chirm E isen . 2nd Edition (1963). Paul Parey, Berlin and Hamburg. DM.24.
Balliere's Veterinary Handbook. Edited by G. N. H enderson and J. S tratton (1963). Balliere, Tindall and Cox, London. 21s.     

BOOK REVIEWS

Book reviewed in this article:
Comparative dermatology textbook: The Skin Microflora and Microbial Skin Disease. By W. C. Noble.
Toxocara detailed: Toxocara and Toxocariasis: Clinical, Epidemiological and Molecular Perspectives. Edited by J. W. Lewis and R. M. Maizels.     

BOOK REVIEWS

Book reviewed in this article:
The British Veterinary Profession 1791–1948 . lain Pattison. J. D. Allen.
H. C. Belschner's Horse Diseases . Fully revised edition by R. J. Rose. Angus and Robertson
The Veterinary Annual, 22nd Issue 1982 . Editors Grunsell and Hill
Fundamentals of Veterinary Ophthalmology , D. H. Slatter. W. B. Saunders, Waltham St, Artarmon
Second National Symposium on Sheep Blowfly and Flystrike in Sheep, 1983—Proceedings. Department of Agriculture
Dog and Cat Nutrition: a Handbook for Students, Veterinarians, Breeders and Owners . Editor A. T. B. Edney
Poultry Diseases . Editors R. F. Gordon and F. T. W. Jordon.
Proceedings, 29th Annual Pfizer Research Conference 19 May 1981 . Pfizer Agricultural Division
Bacterial and Viral Zoonoses . World Health Organisation
Control of Reproductive Functions in Domestic in Animals . W. Jockle and D. R. Lamond.
Bovine Haematology . O. C. Straub and others. Paul Parey
Biomedical and Surgical Aspects of Captive Reptile Husbandry . Frederick L. Frye.
Reproductive Clinical Problems in the Dog . D. E. Jones and J. O. Joshua.
Notes on Pathology for Small Animal Clinicians . D. F. Kelly, V. M. Lucke, C. J. Gaskell. J. Wright and Sons
History of the American Association of Equine Practitioners. The First 25 Years 1954–1979 . W. O. Kester.
The Water Buffalo: New Prospects for an Underutilised Animal . National Research Council     

BOOK REVIEWS

Book reviewed in this article:
Manual of Psittacine Birds Edited by Peter Beynon, Neil Forbes and Martin Lawton
Veterinary Parasitology (2nd edn) By G. M. Urquhart, J. Armour, J. L. Duncan, A. M. Dunn and F. W. Jennings     

BOOK REVIEWS

Book reviewed in this article:
Update on small animal medicine, Current Veterinary Therapy XII. Small Animal Practice. Edited by J. D. Bonagura and R. W. Kirk
Ophthalmic surgery successor, Small Animal Ophthalmic Surgery. Volume 1: Extraocular Procedures - A Family Affair. By K. N. Gelatt and J. P. Gelatt
Neurology for the clinical practitioner, Manual of Small Animal Neurology. Edited by Simon J. Wheeler     

Book Reviews

Book reviewed in this article:
Trauma Management in the Dog and Cat J. E. F. Houlton and P. M. Taylor
Decision Making in Small Animal Radiology
Diseases of Dogs C. W. Prescott.
Small Animal Endocrinology F. H. Drazer.
Manual of Small Animal Nephrology and Urology Edited by D. J. Chew and S. P. DiBartola.
Cardiology; Contemporary Issues in Small Animal Practice Vol. 7 Edited by J. D. Bonagura     

EXAMINATION OF BULLS FOR BREEDING SOUNDNESS

A Report prepared by a Committee of The Australian Veterinary Association comprising: Dr. D. B. Galloway, Professor D. C. Blood, Mr. J. D. Arnort and Mr. W. J. Arnott.
The Report is published by direction of Council for the information of members.     

Book Reviews

Book reviewed in this article:
Techniques of Veterinary Radiography (2nd Edn), 1979. By J. P. Morgan, S. Silverman and W. J. Zontine.
Drugs in Veterinary Practice. By Spinelli and Enos.
Manual of anaesthesia for small animal practice. Ed. by C. M. Ash and R. M. Furber.     

Book Reviews

Book reviewed in this article:
Domestic Animal Behavior for Veterinarians and Animal Scientists K. A. Houpt and T. R. Wolski.
A Standard Guide to Pure Bred Dogs Edited by H. Glover.
A Standard Guide to Cat Breeds Edited by G. Pond and I. Raleigh.
Diseases of the Reptilia, Two volumes Edited by J. E. Cooper and O. F. Jackson.
Dog and Cat Nutrition. A handbook for students, veterinarians, breeders and owners Edited by A. T. B. Edney.
Poultry Diseases, 2nd Edn R. F. Gordon and F. T. W. Jordan.
Genetics for Dog Breeders R. Robinson.
Advances in Veterinary Virology. Refresher course for veterinarians (1982) Edited by M. Sabine.
Canine Dermatoses, Review No. 21 J. M. Keep.
Black's Veterinary Dictionary, 14th Edn Edited by G. P. West.
Non-infectious Diseases of Wildlife Edited by G. L. Hoff and J. W. Davis.     

Book Reviews

Book reviewed in this article:
Canine and Feline Nutritional Requirements (Proceedings of a Symposium organised by The British Small Animals Association). Edited by O liver G raham -J ones . Symposium Publications Division, Pergamon Press, Oxford. 63s.
Drug Presentation and Prescribing by W. R. L. B rown and J. W. H adgraft , The Commonwealth and International Library, Pergamon Press, Oxford. 17s. 6d.