Methods to improve the health of cattle in the tropics: Immunisation and chemoprophylaxis against haemoparasitic infections

Summary A study of methods to improve the health of native cattle in tropical areas of Colombia showed an advantage using immunisation techniques against haemoparasitic infections in comparison with other control methods. The control of anaplasmosis and babesiosis by immunisation of cattle with fully virulentAnaplasma marginale, Babesia argentina andB. bigemina is feasible in tropical cattle when the post-immunisation reaction is controlled by appropriate drug therapy. Chemoprophylaxis was found less effective in controlling haemoparasitic diseases; however, treated cattle surviving the acute stage of infection showed weight gains not significantly different from those of the immunised calves. Both methods were found to be advantageous with calves born and raised in an endemic area of anaplasmosis and babesiosis. Tick and gastrointestinal parasitic control without haemoparasitic control in calves had an advantage over no control system at all. These methods though were inferior to the immunisation and chemoprophylactic techniques.

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Métodos Paar Mejorar La Salud Del Ganado En El Trópico. Inmunización Y Quimoprofilaxis Contra Las Infecciones Hemoparasitarias

Resumen El estudio de métodos para mejorar la salud del ganado nativo en áreas tropicales de Colombia, demostró la bondad de la técnica de la inmunización contra las infecciones hemoparasitarias, en relación con otros métodos utilizados. El control de anaplasmosis y babesiosis a través de la inmunización del ganado con cepas virulentas deAnaplasma marginale, Babesia argentina yB. bigemina, es factible en ganado tropical, cuando la reacción pos-inmunización se controla con drogas apropiadas. La quimoprofilaxis fue menos efectiva para controlar las enfermedades hemoparasiticas; sin embargo, el ganado que se trató después de sufrir el estado agudo de la infección, tuvo aumentos de peso no muy diferentes a los de los terneros inmunizados. Ambos métodos fueron eficientes en terneros nacidos y criados en áreas endémicas de anaplasmosis y babesiosis. El control de garrapatas y parásitos gastrointestinales, sin el control de hemoparásitos en terneros, tuvo ventajas, sobre ningún sistema de control. Estos métodos sin embargo, fueron inferiores en comparación a los técnicas de inmunización y quimoprofilaxis.

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Méthodes Pour Améliorer la Santé des Bovins Tropicaux. Immunisation Et Chimioprophylaxie Contre Les Infections Parasitaires Sanguines

Résumé L'étude des diverses méthodes pour améliorer le santé du bétail local dans les régions tropicales de Colombie montre que les techniques d'immunisation contre les infections parasitaires sanguines sont supérieures aux autres moyens de lutte. La lutte contre l'anaplasmose et les babésioses par immunisation à l'aide deAnaplasma marginale, Babesia argentina etBabesia bigemina pleinement virulents est possible chez le bétail tropical lorsque les réactions post-vaccinales peuvent être traitées par une chimiothérapie appropriée.La chimioprophylaxie a été reconnue comme étant moins efficace pour lutter contre ces hémoparasitoses; toutefois le bétail ayant survécu, grâce au traitement, à une atteinte aiguë de la maladie montre des gains de poids qui ne sont pas significativement supérieurs à ceux des veaux immunisés.Les deux méthodes se sont montrées profitables chez les veaux nés et élevés dans une région où anaplasmose et babésioses régnent à l'état endémique.Chez les veaux, la lutte contre les tiques et les parasites gastro-intestinaux, sans lutte contre les hémo-parasites, présente des avantages par rapport à l'absence totale de lutte. Ces méthodes sont cependant inférieures à l'immunisation et à la chimioprophylaxie.

     

Efficacy of moxidectin 0.5% pour-on against naturally acquired nematode infections in cattle in the Mexican tropics

The efficacy of 0.5% moxidectin pour-on in cows with naturally acquired nematode infections was evaluated. The study was carried out in a ranch in Veracruz, Mexico. Four groups of 15 cows were randomly allocated. Animals in the treated group received 0.5% moxidectin pour-on at a dose of 0.5 mg/kg body weight on a single occasion. The other two groups remained as untreated controls. Fecal samples from all cattle were taken on days 0 (pre-treatment), 7, 14, 28 and 60 (post-treatment, PT). Fecal egg-counts were determined using a modified McMaster technique and fecal cultures were performed to identify gastrointestinal nematodes infected larvae (L(3)). Treatment with moxidectin was associated with a significant reduction in fecal trichostrongyle egg-counts compared with the controls; efficacy was 100% at 28 days PT. Haemonchus spp. and Strongyloides spp. were the two genera identified from coprocultures.     

Dairy cattle crossbreeding in the tropics: Choice of crossbreeding strategy

Summary Two strategies for crossbreeding of indigenous and exotic cattle for milk production in the tropics,viz. rotational crossing and formation of a composite breed, have been compared. Genetic considerations suggest that rotational crossing would lead to somewhat better dairy performance, mainly because of more heterozygosity. Predictions based on the performance of adjacent genetic groups as obtained from a comprehensive literature review point in the same direction.Rotational crossbreeding depends on a continuous introduction of bulls of both parental breeds. The herd will consist of 2 (or more) genetic groups, which might be inconvenient for breeding arrangements, but provides more flexibility. The system requires good organisation and is most suitable in large farms. In small scale dairying the composite breed strategy is the most practical approach to dairy cattle breeding in the tropics.

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Cruzamiento De Vacuno Lechero En Los Tropicos: Eleccion De La Estrategia De Cruzamiento

Resumen El artículo compara dos estrategias de cruzamiento entre vacuno lechero exótico e indígena en los trópicos: el cruzamiento rotativo y la formación de una raza híbrida. Las consideraciones genéticas sugieren que el cruzamiento rotativo debería llevar a una mejor producción lechera, sobre todo debido a un aumento de la heterozigosis. Las predicciones basadas en el rendimiento de grupos genéticos adyacentes determinado a partir de una revisión bibliográfica apuntan en la misma dirección.El cruzamiento rotativo require una introducción contínua de toros de las dos razas parentales. El rebaño consistiría de 2 (o más) grupos genéticos, lo que -si bien permite una mayor flexibilidad- puede dificultar la planificación de la reproducción. El sistema requiere una buena organización y resulta más factible en explotaciones grandes. En explotaciones pequeñas de los trópicos, la formación de una raza híbrida es la estrategia más prática en lo que a cría de vacuno lechero se refiere.

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Croisement Du Cheptel Laitier Sous Les Tropiques: Choix De La Strategie De Croisement

Résumé Deux stratégies pour le croisement entre le bétail indigène et le bétail exotique pour la production laitière sous les Tropiques, à savoir le croisement rotationnel et la formation d'une race composite, ont été comparées. Des considérations génétiques suggèrent que le croisement rotationnel amènerait quelque chose de plus performant au niveau laitièr, principalement dù à l'augmentation de hétérozygotie. Des prédictions, basées sur les performances de groupes génétiques adjacents, issues de l'étude complète de la littérature donnent la même analyse.Le croisement rotationnel est basé sur l'introduction continuelle de taureaux venant des deux races parentales. La horde consistera en 2 (ou plus) groupes génétiques, ce qui peut être gênant pour le croisement mais permet plus de flexibilité. Le système demande une bonne organisation et est préférable dans les grandes fermes. A une échelle de production laitiere plus faible la stratégie de la race composite est l'approche la plus pratique pour le croisement du cheptel laitier sous les Tropiques.

     

Effect of moxidectin against natural infestation of the cattle tick Boophilus microplus (Acarina: Ixodidae) in the Mexican tropics

The study was divided in to two trials and carried out in a ranch in eastern Yucatan state, Mexico. In the first trial, two groups of 15 BostaurusxBosindicus heifers, 6-12 month of age and naturally infested with Boophilus microplus ticks were used. Heifers in Group 1 were treated with a 1% injectable formulation of moxidectin at the dose of 0.20mg/kg body weight by subcutaneous injection. The other group remained as untreated controls. Number of immature and engorging female ticks were assessed on days 0, 7, 14, 21, 28 and 35 post-treatment (PT). The efficacy of moxidectin on adult ticks from day 7 to 28 PT was greater than 95%. The efficacy decreased to 74.9% by day 35. In the second trial, animals in Group 1 were treated with the moxidectin product as before, while cattle in Group 2 were treated according to the routine procedure for the control of ticks on that property (125 g/l amitraz as a dip). Treatment of all cattle was repeated four times at intervals of 28 days. The efficacy of the experimental moxidectin treatment was similar to that of the routine amitraz treatment, i.e., greater than 99%.     

Persistent efficacy of doramectin and moxidectin against Cooperia oncophora infections in cattle

Duplicate studies in France and Northern Ireland were carried out to determine the persistent efficacy of topical moxidectin and doramectin against natural infections of Cooperia oncophora. In each study, groups of 15 nematode-na?ve calves were treated either with topical doramectin or moxidectin, and put out to graze on pasture contaminated with C. oncophora infective larvae. The persistent efficacy for preventing establishment of infection was assessed by the time to faecal egg excretion of C. oncophora eggs. It was found that the moxidectin treatment prevented infection for less than 10 days and the effect of doramectin lasted for 24 days.     

Efficacy of moxidectin against naturally acquired nematode infections in cattle.

The efficacy of moxidectin, a new endectocide against natural nematode infections, was evaluated. Twenty-five calves were divided into two groups of eight calves each and a third group of nine calves. Moxidectin was administered s.c. to two groups (I, 0.2 mg kg-1 body weight (BW); II, 0.3 mg kg-1 BW) and the third group (III) received the vehicle (placebo) s.c. Two pre-treatment and one post-treatment faecal nematode egg count determinations were made from all calves, and they were necropsied 2 weeks after treatment for the identification and enumeration of nematode parasites. Group III calves, which received the drug-free vehicle, harboured eight species of nematodes (Ostertagia ostertagi, Trichostrongylus axei, Cooperia oncophora, Cooperia punctata, Nematodirus helvetianus, Trichuris discolor, Oesophagostomum radiatum and Dictyocaulus viviparus). The mean total worm burden for this group was 8935. There was a significant reduction in the numbers of many species of nematodes (Ostertagia, Trichostrongylus, Cooperia and Nematodirus) in both treated groups. Cooperia oncophora was reduced by 94% in Group I and by 96% in Group II, while all other nematode species were reduced by 99%. Immature stages of Ostertagia and Nematodirus were significantly reduced in the two treated groups. Two weeks after treatment, the mean faecal egg counts of both treated groups were reduced by more than 98%. There was no significant difference in mean total worm burdens or egg counts between the two treated groups.     

阿维菌素控释丸对牛寄生虫的驱杀效果观察

山东省是养牛大省,据报道,截止1997年底,山东省共存栏肉牛1460.80万头.寄生虫病,特别是痒螨病是危害山东养牛业的主要疾病.     

Optimum use of milk in traditionally managed cattle herds in the tropics

In traditional cattle systems in the tropics, the milk produced is generally shared between the calf and the cattle keeper. This literature review evaluates the socio-economic aspects related to milk production and milk use in traditional cattle systems and identifies the best strategies of milk allocation in order to improve food security and maximise income. The available literature indicates that milk, in terms of economic, social and subsistence value, is more valuable than meat. Thus, under the conditions that characterise traditional cattle systems in the tropics, it is appropriate to have a higher milk offtake at the expense of calf growth. This review also found that certain management practices, such as restricted suckling, can be useful to minimise mortality of calves, while improving milk offtake for human consumption.     

Use of an albendazole bolus against gastrointestinal nematode infections in first year cattle

Thirty first year grazing calves were allocated to two groups of 15 calves each on the basis of bodyweight and were administered albendazole boli or placebo boli, respectively, 30 days after turnout. The albendazole bolus prevented the nematode egg output almost completely for about 4 months, whereas the controls had mean egg counts of up to 206. Pepsinogen concentrations were significantly higher in the control group and reached mean values of 3055 mU tyrosine compared to less than 1000 mU tyrosine in the albendazole treated group after bolus administration. Pasture contamination with trichostrongylid larvae was markedly lower on pastures of the albendazole group than on the controls. Mean weight gains were significantly higher in the albendazole group than in the controls with a difference of 10.7 kg per animal at the end of the season.     

提高架子牛育肥效果的技术措施

1架子牛的选择 1．1品种 供肥育的架子牛多为改良牛，可选择以夏洛莱、海福特、西门塔尔、皮埃蒙特牛为父本，本地黄牛为母本的F1、F2代杂交种牛。这些牛增重快、肉质好、饲料报酬高、肥育效果明显。     

Approaches to modeling intramammary infections in dairy cattle

In this paper, three approaches (Markov processes, discrete-event simulation, and differential equations) to modeling intramammary infections (IMI; focusing on the dynamic changes between uninfected, subclinical, and clinical udder-health states) are described. The objectives were to describe the various approaches to modeling intramammary infections, determine if simulations of the examples of the three approaches yield stable prevalences, and discuss the approaches' limitations. The literature review showed that there is no agreement on the proportion of animals that change health states. The approach of discrete-event simulation modeling included the most cow-level risk factors and udder-health states (hence, was judged to replicated best the dynamics of the infection process) and yielded stable prevalences for all udder-health states. However, there remain parts of the dynamics that need further research. These include the pathogen-specific probabilities and times of occurrence for: regression of clinical IMI to subclinical IMI, flare-up of subclinical IMI to clinical IMI, and incidence of subclinical IMI. Also, the assumption in all current approaches of homogenous mixing is violated because the primary contact structure for contagious pathogens during milking is either between cows through residual infectious milk in the milking machine or within a cow by vacuum fluctuations or teat-cup liner slips. Better contact structures should be incorporated so that the effects of control strategies can be better-estimated. Moreover, the three modeling approaches discussed assumed that all non-infected quarters are susceptible to infection—which might be denied by work in genetic resistance.     

Persistent efficacy of doramectin pour-on against artificially induced infections of nematodes in cattle.

Two studies were conducted to determine the persistent efficacy of doramectin pour-on against an artificial, trickle challenge of mixed nematodes in calves. In each study, 42, 4-8 months old calves were randomly assigned into four groups of 10 animals each (T1-T4), plus two larval-viability monitor animals. All animals were treated with fenbendazole (10 mg kg(-1)) 14 days prior to the start of the study to clear any existing infection. Doramectin pour-on at 500 microg kg(-1) was used on each animal in Groups T2, T3, and T4 with intervals of 1 week (Day 0, 7, and 14, respectively). Calves in Group T1 were treated with saline solution on Day 0 and at the same volumetric rate (1 ml 10 kg(-1)) as the doramectin treated animals. All treatments were applied in a single passage along the midline of the back, from the withers to the tailhead. Subsequently, trickle inoculations with infective larvae were administered to all calves for 22 consecutive days (Days 14-35). Doramectin pour-on provided > or = 91.9% efficacy against challenge with Dictyocaulus viviparus, Haemonchus spp., and Ostertagia ostertagi for up to 35 days post-treatment and against challenge with Cooperia oncophora, Cooperia punctata, and Oesophagostomum radiatum for up to 28 days post-treatment.     

Dairy science and health in the tropics: challenges and opportunities for the next decades

In the next two decades, the world population will increase significantly; the majority in the developing countries located in the tropics of Africa, Asia, Latin America, and the Caribbean. To feed such a population, it is necessary to increase the availability of food, particularly high-value animal protein foods produced locally, namely meat and dairy products. Dairy production in tropical regions has a lot of growth potential, but also poses a series of problems, particularly as dairy production systems were developed in temperate countries and in most cases are difficult to implement in the tropics. Drawbacks include hot weather and heat stress, the lack of availability of adequate feeds, poor infrastructure, and cold chain and the competition with cheap imports from temperate countries. This position paper reviews the major drawbacks in dairy production for the five major dairy species: cattle, water buffalo, sheep, goat, and camel, as well as the future trends in research and development. It also concerns the major trends in reproduction and production systems and health issues as well as environmental concerns, particularly those related to greenhouse gas emissions. Tropical Animal Health and Production now launches a topical collection on Tropical Dairy Science. We aim to publish interesting and significant papers in tropical dairy science. On behalf of the editorial board of the Tropical Animal Health and Production, we would like to invite all authors working in this field to submit their works on this topic to this topical collection in our journal.

     

Genetic immunisation of cattle against bovine herpesvirus 1: glycoprotein gD confers higher protection than glycoprotein gC or tegument protein VP8

Bovine herpesvirus 1 (BoHV-1) has frequently been used as a model for testing parameters affecting DNA immunisation in large animals like cattle. However, the selection of target antigens has been poorly studied, and most of the experiments have been conducted in mice. In the present study, we demonstrated in cattle that a DNA vaccine encoding BoHV-1 glycoprotein gD induces higher neutralising antibody titres than vaccines encoding BoHV-1 gC. Additionally, we show that a DNA vaccine encoding a secreted form of gD induces a higher immune response than a vaccine encoding full-length gD. However, the enhanced immunogenicity associated with the secretion of gD could not be extended to the glycoprotein gC. The current study also describes for the first time the development and the evaluation of a DNA vaccine encoding the major tegument protein VP8. This construct, which is the first BoHV-1 plasmid vaccine candidate that is not directed against a surface glycoprotein, induced a high BoHV-1 specific cellular immunity but no humoral immune response. The calves vaccinated with the constructs encoding full-length and truncated gD showed a non-significant tenfold reduction of virus excretion after challenge. Those calves also excreted virus for significantly (p < 0.05) shorter periods (1.5 days) than the non-vaccinated controls. The other constructs encoding gC and VP8 antigens induced no virological protection as compared to controls. Altogether the DNA vaccines induced weaker immunity and protection than conventional marker vaccines tested previously, confirming the difficulty to develop efficient DNA vaccines in large species.     

Immunisation of cattle against theileriosis in Coast Province, Kenya: laboratory evaluation of a Theileria parva parva stabilate for use in 'infection and treatment' immunisation in the field

Theileria parva parva Marikebuni stock, previously shown to give good protection to immunised cattle in Kilifi District, Coast Province of Kenya, was chosen for large scale immunisation in the district. A large sporozoite stabilate was prepared and evaluated for efficacy and safety in the 'infection and treatment' method, using a long or short acting formulation of oxytetracycline. Susceptible cattle were infected with selected doses of stabilate (10(0), 10(-1), 10(-1.7) and left either as untreated controls, or treated with one of the two oxytetracycline formulations. It was concluded that stabilate dilution at 10(-0.7) or 10(-1) in combination with either formulation of oxytetracycline would effect satisfactory immunisation. The short acting oxytetracycline treatment was judged to be the most efficacious in protecting cattle against homologous challenge. On heterologous challenge it was found that T p parva Marikebuni immune cattle were protected against seven T p parva stocks from Kilifi District and also against four stocks of T p parva from other areas of Kenya. In addition, the Marikebuni stock provided partial protection against challenge by T p lawrencei stocks. Furthermore, cattle immune to T p parva and T p lawrencei were protected against lethal challenge of T p parva Marikebuni stock. Thus, it appears that large scale immunisation of cattle against theileriosis in Kilifi District could be undertaken using the Marikebuni stock. With continued assessment, this stock could provide a master theilerial stock for immunisation against cattle theileriosis in areas free of buffaloes elsewhere in Kenya.     

提高轮供青饲料的措施

青饲料包括青绿饲料和多汁饲料,其特点是青绿、多汁、柔嫩、适口性好、消化率高,是草食动物的重要营养物质。青饲料是奶牛必不可少的饲料,对提高奶牛的泌乳量和品质都有重要作用。青饲料轮供就是要保证奶牛一年四季优质青饲料的均衡供应。目前,一些奶牛场由于不能均衡供应青饲料,导致生产起伏波动,给生产带来较大损失。因此,组织好青饲料的均衡供应有重要的现实意义。1　提高青饲料产量和品质的措施1 1　播种　播种前要对种子进行处理,剔除坏死种子、杂草种子以及禾草种子的芒,打破种子休眠,以保证播种质量。对种子进行预防病、虫害的处理…