杜伯文幼犬饲养管理要点

幼犬是指45日龄至6月龄的犬,此阶段是犬生长发育最快、可塑性最大的时期。杜伯文幼犬性情活泼,好动贪玩,精力旺盛,食量大,幼犬被毛短,绒毛较少,各器官尚未发育成熟,抵抗力和适应能力都相对较弱,还不具备独立的生活能力,容易发生各种疾病,特别易发皮肤病。     

Multiple skin tumours in a Doberman Pinscher with colour dilution alopecia

Abstract An 11-year-old Doberman Pinscher with clinical and histological skin features consistent with colour dilution alopecia had a long history of skin disease. The animal had hundreds of papules affecting the ‘blue’ haired áreas of the hair coat. The predominant skin lésions included keratinizing infundibular cysts, keratin horns, perifollicular dermatitis, and sebaceous hyperplasia; these lésions were often accompanied by fürunculosis and suppurative panniculitis. Over a 9-month period, 32 lésions were examined histologically, which included two lipomas, one infiltrative lipoma, one squamous papilloma, two mast cell tumours, four cavernous haemangiomas, one haemangiosarcoma, and three melanomas. It is unknown at present whether the colour dilution phenotype confers increased risk for tumours of the skin and or subcutaneous tissues. Résumé— Un doberman de 11 ans avec des manifestations cutanées cliniques et histologiques compatibles avec le díagnostic d'alopécie des couleurs diluées avait une longue histoire de problèmes cutanés. L'animal présentait des centaines de papules affectant les zones de couleur bleue. Les lésions cutanées prédominantes consistaient en kystes infundibulaires kératinisants, cornes cutanées, dermatite périfolliculaire et hyperplasie sébacée; ces lésions s'accompagnaient souvent de füronculose et de panniculite suppurative. Sur une période de 9 mois, 32 lésions ont fait l'objet d'un examen histologique, dont deux lipomes, un lipome infiltrant, un papillome, deux mastocytomes, quatre hémangiomes caverneux, un hémangiosarcome, et trois mélanomes. On ne sait actuellement pas si le phénotype couleur diluée constitue un facteur de risque accru pour les tumeurs de la peau et des tissus sous cutanés. [Madewell, B. R., Ihrke, P. J., Griffey, S. M. Multiple skin tumours in a Doberman Pinscher with colour dilution alopecia. (Tumeurs cutanées multiples chez un doberman présentant une alopécie des couleurs diluées.) Veterinary Dermatology 1997; 8 : 59–62.] Resumen Un doberman pinscher de 11 años con caracteristicas clinicas e histológicas compatibles con alopecia de color diluido tenia una larga historia de enfermedad cutanea. El animal presentaba centenares de pápulas afectando las áreas de pelo “azul”. Las lesiones prédominantes incluian quistes infundibulares queratinizados, cuernos de queratina, dermatitis perifolicular e hiperplasia sebácea; estas lesiones se acompañaban de fürunculosis y paniculitis supurativa. Durante un periodo de 9 meses, 32 lesiones fueron examinadas histológicamente, incluyendo 2 lipomas, un lipoma infiltrativo, un papiloma escamoso, dos mastocitomas, cuatro hemangiomas cavernosos, un hemangiosarcoma y tres melanomas. Se desconoce aún si el fenotipo de color diluido aumenta el riesgo para la aparición de tumores en tejidos cutáneos y subcutáneos. [Madewell, B. R., Ihrke, P. J., Griffey, S. M. Multiple skin tumours in a Doberman Pinscher with colour dilution alopecia. (Multiples tumores cutáneos en un Doberman Pinscher con alopecia de color diluido.) Veterinary Dermatology 1997; 8 : 59–62.] Zusammenfassung— Ein elfjähriger Dobermann mit klinischen und histologischen Befunden, die bei Farbmutantenalopezie auftreten, wies eine lange Vorgeschichte mit Hautkrankheiten auf. Das Tier zeigte Hunderte von Papeln, die die “blau” behaarten Bezirke des Felles betrafen. Die vorherrschenden Hautveränderungen bestanden in keratinisierenden infundibulären Zysten, Keratinhörnern, perifollikulärer Dermatitis und Talgdrüsenhyperplasie; diese Veränderungen wurden oft von Furunkulose und eitriger Pannikulitis begleitet. Über eine Zeitspanne von 9 Monaten wurden 32 Veränderungen histologisch untersucht, wovon zwei in Lipomen bestanden, eine in einem infiltrativen Lipom, eine in einem squamösen Papillom, zwei in Mastzelltumoren, vier in kavernösen Hämangiomen, eine in einem Hämangiosarkom und drei in Melanomen. Es ist zur Zeit nicht bekannt, ob der Phänotyp mit der Farbverdünnung mit einem erhöhten Risiko für Tumoren der Haut und/oder des subkutanen Gewebes einhergeht. [Madewell, B. R., Ihrke, P. J., Griffey, S. M. Multiple skin tumours in a Doberman Pinscher with colour dilution alopecia. (Multiple Hauttumoren bei einem Dobermann mit Farbmutantenalopezie.) Veterinary Dermatology 1997; 8 : 59–62.]     

杜伯文种母犬的饲养管理初探

科学饲养管理杜伯文种母犬,对这一引进犬种能较快适应国内环境(风土驯化)至关重要。笔者通过查阅国内外资料,同时根据杜伯文犬自身的生理、生化及生活习性等特征,以及环境气候因素,有针对性地对杜伯文种母犬的饲养管理进行了应用研究,取得了较好的效果。一、杜伯文犬的特性杜伯文犬原产于德国,是用多个品种犬杂交培育而成,具有以下主要的特性:(1)聪慧、警觉性高、游戏欲望强、反应灵敏、皮肤敏感、肌肉强健、体力充沛、善于奔跑,公犬表现为暴躁冲动,母犬显得宁静而敏捷;(2)杜伯文犬食欲旺盛,并能适应多种颗粒饲料;(3)不具备全身性的绒毛层,…     

罗杜杂交犬的杂交效果分析

罗杜杂交犬是由罗威纳公犬与杜伯文母犬杂交的杂交一代犬.罗威纳犬和杜伯文犬的毛色均是黑色带棕色斑纹,但在体型和行为性状上各有特点,罗威纳公犬具有胆大凶猛、作业沉稳、条件反射巩固等优点,但体型较笨拙、灵活性较差;杜伯文体型结构匀称紧凑,聪慧、灵活性好,但易冲动、服从性差.选择罗威纳犬与杜伯文犬作为杂交亲本,开展杂交试验,期望在杂交后代的体型、体能、胆量、凶猛性等遗传力高和后期表现的性状方面形成互补,在神经活动转换、胆量、衔取、服从性及训练接受能力等方面产生杂种优势或互补.     

罗威纳与杜伯文杂交一代犬特性分析

<正>罗威纳与杜伯文杂交一代犬是由罗威纳与杜伯文杂交而成。经过近3年的观察与训练,发现罗威纳与杜伯文杂交一代犬具有明显的杂交优势:既遗传了罗威纳犬胆大凶猛、作业沉稳、条件反射巩固等优点,又遗传了杜伯文体形结构匀称紧凑、聪慧、灵活性好的优良品质。     

X-Chromosomal Monosomy (77, XO) in a Doberman Pinscher With Gonadal Dysgenesis

A 6-month-old stunted female Doberman Pinscher was found to have a 77,X0 chromosomal complement. The ovaries were small, consisting primarily of interstitial-type cells and solid epithelial cords. The dam, sire, and a male littermate had normal karyotypes.     

罗杜杂交犬飞扑撞击假设敌训练初探

随着全国各级公安机关大规模配发巡逻犬用于城区巡逻,在社会面的控制及预防犯罪中起到较好的震慑作用,如何提升其实战效能则成为一个重要课题。切实解决巡逻犬在实战中放的问题是提升警犬使用效能、服务一线警务工作的一种思路。巡逻犬佩戴口笼出勤不     

Congenital blindness with ocular developmental anomalies, including retinal dysplasia, in Doberman Pinscher dogs

Hereditary, congenital blindness was studied in 15 Doberman Pinscher pups. The eyes were smaller than normal, and there was complete absence of the anterior chamber, aphakia, retinal detachment, and dysplasia as well as an irregular swelling and partial depigmentation of the retinal pigment epithelial cells. It was concluded that the condition was inherited as a recessive, autosomal trait.     

Effect of Desmopressin Acetate on Bleeding Times and Plasma von Willebrand Factor in Doberman Pinscher Dogs with von Willebrand''s Disease

Effects of desmopressin acetate (1-desamino-8-D-arginine vasopressin [DDAVP]) on plasma von Willebrand factor (vWf) were studied in 12 purebred Doberman pinschers confirmed to have von Willebrand's disease (vWd) (plasma vWf antigen [vWf:Ag] concentrations, less than 30 U/dl). Twelve dogs had subnormal plasma botrocetin cofactor (BCf) activity and 11 dogs had prolonged buccal mucosa bleeding times. Tranquilization of three dogs with lenperone and three dogs with xylazine did not induce significant changes in mean plasma vWf:Ag concentrations or mean BCf activities. Thirty and 120 minutes after administration of DDAVP (1 micrograms/kg subcutaneously), there was significant shortening of the mean buccal mucosa bleeding time. Ten dogs responded to DDAVP with increases in BCf activity which exceeded 10 U/dl at 30 or 120 minutes, or both, after the drug was administered. At the same time, increases in plasma vWf:Ag concentrations were smaller than the increases in BCf activity. It was shown by multimeric analysis that primarily the higher molecular weight forms of vWf increased in plasma in response to DDAVP.     

Basosquamous carcinoma with systemic metastasis in a miniature Pinscher

Basosquamous carcinoma (BSCC) is a rare malignancy, primarily composed of basal cells with foci of squamous differentiation. It is considered to be histologically an intermediate type between basal cell carcinoma and squamous cell carcinoma, and is known to have aggressive behaviors. BSCC occurred in a 17-year-old female minipin with a history of surgical excision for a mammary tumor. The right upper hindlimb was severely enlarged to 8 x 5 cm. Cross-section showed a homogenous white to yellow-white mass compressing the surrounding muscular tissues. The tumor metastasized also to the lungs, heart, abdominal cavity, liver and salivary gland. Microscopically, basaloid cells were crowded into solid nests or lobules separated by well-developed fibrous tissues with occasional keratinizations. Since there was no skin lesions, the tumor is assumed to be originated from the formerly present tumor in mammary gland. To our literature review, this case is the first BSCC with systemic metastasis in a dog.     

Color dilution alopecia in a blue Doberman pinscher crossbreed

A 6-year-old male, blue Doberman pinscher crossbreed was presented with coat abnormalities; in particular, flank alopecia and pruritus. Based on medical the history, clinical evidence, and histopathological examination, color dilution alopecia was diagnosed. The dog was with oral melatonin treated for 3 months without success.     

Systemic fungal infection in a dog: a unique case in Ireland

A three year old male entire Staffordshire bull terrier was referred to University College Dublin Veterinary Hospital, with a two week history of fever, inflammation of the right hock, lameness on the right hindlimb, peripheral lymphadenopathy and gastrointestinal signs (vomiting and diarrhoea). For the preceding three months the dog had been treated for atopic dermatitis with oral ciclosporin (5 mg/kg, PO, q 24 hours).Cytological analysis of the affected lymph nodes demonstrated fungal-like organisms predominantly contained within macrophages. Subsequent fungal culture and microscopic identification confirmed the presence of a Byssochlamys sp. This fungus is a saprophytic organism which has been associated with mycotoxin production. It has not previously been identified as a cause of systemic infection in animals or humans.Ciclosporin was discontinued, and a second generation triazole, voriconazole prescribed at a dose of 6 mg/kg for the first two doses, and continued at 3 mg/kg every 12 hours for six months. There was an excellent response. Follow-up examination five weeks after treatment was completed confirmed remission of the disease. The dog remains alive and well three years later.The present case represents an unusual fungal infection in a dog secondary to immunosuppressive therapy with ciclosporin. Such a possibility should be considered in animals presenting with signs consistent with systemic infection when receiving immunosuppressive medication.     

Systemic infection with Mortierella wolfii following abortion in a cow

Severe meningoencephalitis and endometritis associated with necrotizing vasculitis, thrombosis, and infarction were found at necropsy of a 4-year-old Aberdeen Angus cow with a history of abortion and neurological signs. Focal pyogranulomatous pneumonia and nephritis were also present. Fungal hyphae typical of zygomycetes were abundant within lesions, and Mortierella wolfii was cultured from multiple tissues. This is believed to be the first report of systemic mortierellosis following abortion in North America, and the second reported instance of encephalitis caused by M. wolfii in a cow.     

Systemic autoimmune disease and concurrent nematode infection in a dog

Systemic lupus erythematosus was diagnosed in a dog with concurrent nematode infection. The clinical signs of disease were unusually severe and included multiple neurologic deficits, polyarthritis, and weight loss. The dog was thrombocytopenic, and serotest results included positive lupus erythematosus test, positive rheumatoid factor test, positive antinuclear antibody test, hypergammaglobulinemia, and high platelet-associated IgG concentration. After treatment of hookworm, whipworm, and heartworm infections concurrently with corticosteroid and empiric treatment, the dog's condition improved. However, 10 days later, cyclophosphamide administration was necessary for continued immunosuppression. The dog was euthanatized because of progressive deterioration and development of canine coronavirus diarrhea. Serotest data generated from the dog's serum obtained at the time of referral suggested that autoantibodies and circulating immune complexes may have included IgE isotypes.     

Long-term management of vaccine-induced refractory ischemic dermatopathy in a Miniature Pinscher puppy

A 2-month-old intact female Miniature Pinscher puppy presented with footpad swelling and crusted pustules of ear pinnae. The dog had been vaccinated with a polyvalent canine vaccine 5 days prior to the onset of clinical signs. With the history of recent vaccination, the clinical presentation and the histopathological observations were suggestive of ischemic dermatopathy. Treatment involved oral prednisolone, azathioprine, and other immune modulating drugs, which did not work. Chlorambucil plus cyclosporine therapy was initiated for vigorous immune suppression after rush therapy using intravenous immunoglobulin. Clinical signs again gradually improved with no relapse or side effects, even at a 4-month follow-up. The case report is suggested ischemic dermatopathy refractory to conventional therapy and suggests effective approaches to long-term management of the disease.     

Systemic granulomatous disease and sialometaplasia in a dog with Bartonella infection

Systemic granulomatous disease involving the spleen, heart, lymph nodes, omentum, liver, kidney, lung, mediastinum, and salivary glands developed in an 8-year-old Rottweiler. The dog also had sialometaplasia of both submandibular salivary glands. Bartonella henselae and B. vinsonii subsp. berkhoffii DNA was amplified from the salivary gland by polymerase chain reaction analysis. Bartonellae may be the cause of this systemic disease, but to the authors' knowledge, involvement of omentum, mediastinum, and salivary glands has not previously been reported in association with Bartonella infection. Bartonellae should be considered potential causes of sialometaplasia.     

Systemic blastomycosis in a horse.

Progressive multisystemic disease caused by Blastomyces dermatitidis was diagnosed in a 17-year-old Quarter horse broodmare. The mare had been treated unsuccessfully with antibiotics for mastitis 3 months postpartum. The disease progressed to exudative cutaneous lesions affecting the ventrum, pectoral region, and limbs accompanied by weight loss across several months. Yeast bodies were observed in swabs of the cutaneous exudate, suggesting a clinical diagnosis of blastomycosis. Following referral, pleural effusion, cavitated lung lesions, and hyperproteinemia were identified, and the mare was euthanized because of poor prognosis. Necropsy revealed extensive pyogranulomas in the mammary gland, skin, subcutaneous tissues, and lungs, accompanied by thrombi in major blood vessels of the lungs and hind limbs. Histologically, pyogranulomatous inflammation was evident in many tissues, and fungal organisms were seen in sections of mammary gland, skin, subcutis, pericardium, and lung. Blastomyces dermatitidis was cultured from mammary tissue, lungs, lymph node, and an inguinal abscess. Although blastomycosis is endemic in the area of origin of the mare in northwestern Wisconsin, the disease is extremely rare in horses and hence easily misdiagnosed. Unique features of this case included the extent of mammary gland involvement and the presence of thrombi in multiple sites.     

Disc-associated wobbler syndrome in the Doberman pinscher

Disc-associated wobbler syndrome is a subset of the diverse canine wobbler complex. Disc-associated wobbler disease can occur in many large-breed dogs but the vast majority are middle-aged Doberman Pinschers. Dorsal annulus hypertrophy and protrusion is the hallmark lesion with variable association of dorsal ligamentum flavum hypertrophy and bony malformations. Chronic caudal cervical spinal cord compression results in the clinical signs. Instability, primary disc degeneration, and conformational etiologies have been incriminated. The clinical course usually entails chronic progressive paraparesis to tetraparesis with insidious onset. Acute onset or exacerbations are less common. Diagnosis is based upon history, neurologic examination, and radiography/myelography. Long-term conservative therapy is only palliative and usually leads to the demise of the animal. Surgical therapy offers the potential of a cure but at significant risk of morbidity and mortality. Surgical treatment consists primarily of decompressive techniques with or without stabilization. The numerous surgical techniques utilized highlight the variability of the lesions and the lack of universal acceptance of any one technique. Decompression is accomplished by surgical access to the vertebral canal to physically remove the abnormal ligament and/or bony material. Alternatively, distraction combined with fusion of the vertebrae adjacent to the offending disc may reduce the hypertrophied/prolapsed dorsal annulus. Regardless of the procedure, postoperative management may be fraught with complications that require special considerations.