对“阿司匹林”新认识

阿司匹林被称为"百年圣药",在心脑血管病防治中广泛应用。随着研究的深入,人们对阿司匹林在心脑血管临床中应用的老话题。(包括剂量、出血、联用、疗     

生物高能臭氧液体发生器

为了克服臭氧发生器治疗疾病的不足之处，本专利提供了一种生物高能臭氧液体发生器，该生物高能臭氧液体发生器，对机体缺氧需呼吸道吸氧的病人均适用，而且疗效较呼吸道给氧好，在肿瘤的治疗和心脑血管病防治方面有很好的疗效作用。     

提取天然有机硒的方法

硒是人体所必需的元素，如果人体硒的摄入量长期低于供给量，则会造成体内缺硒而引起地方病或其它疾病。近年来的一系列研究表明硒元素对人体抗衰老、预防和治疗近视眼、防治癌症、心脑血管病有明显的疗效，因此人体补硒对于防治各种疾病保持身体健康极为重要。但是由于元素硒不溶于水，吸收性能较差，虽具有一定的防病效果，但有副作用。 天然有机硒是一种含硒量高、对人体抗衰老、防治近视、癌症、心脑血管等疾病有特殊疗效的制品。它是用新鲜山野菜或野生石蒜科植物全株作提取原料，步骤如下： 沉淀沉降物烘干即天然有机硒母料。 研究证…     

菜芙蓉栽培与利用

2003年8月份中国农业科学院研究员唐益雄教授在河北邢台考查植物资源时,意外地在内邱发现了菜芙蓉植物,这种植物花朵艳丽,且有香味,一直被作为赏花种植。菜芙蓉的重现,不仅是一种濒危植物的重生,也不单是生物界又添一新成员,更可贵的是这种植物能提取高达6％植物黄酮,生物黄酮是医学界公认预防和治疗心脑血管病的首选药物,心脑血管病又是影响人们健康     

应用粘虫胶防治林木害虫

在林业无公害生产中,应用粘虫胶对春尺蛾、松毛虫进行防治,可以显著减少化学农药的用量,降低防治成本,提高防治效果。只要使用及时,防治落叶松毛虫可以达到98%以上的防治效果,防治春尺蛾可以达到95%以上的防效。     

病虫害在苗圃育苗方面的创新性防治

指出了随着苗圃育苗技术在林业种植中的提高,林业质量获得了很大的发展,可以说苗木质量的好坏直接关系到整个林业产业质量的提升,所以对于苗木进行病虫害的防治具有很重要的意义。传统的苗圃病虫防治方法主要是通过喷洒化学农药进行防治,但是会产生严重的污染和有害物质,这种防治病虫害的方式已经不能满足现代化绿色环保生产的要求,通过创新性方法的分析和探讨,可以为苗圃育苗的病虫防治提供更好的途径。     

马尾松毛虫防治关键期与防治历

本文分析了马尾松毛虫（Dendrolimus punctatus Walker）防治关键期,发现马尾松毛虫种群密度快速增长期在增殖期末期,在增殖期末期开展有效的防治,可以预防马尾松毛虫暴发成灾,并依据这一原理编制了马尾松毛虫防治月历和防治周期历。     

人工地箭防治中华鼢鼠技术

简要介绍了山西省右玉地区使用人工地箭防治中华鼢鼠的技术,总结了防治效果,目前人工地箭防治的成功率为23.21%.分析了在各种情况下,人工地箭防治鼢鼠失败的原因,在此基础上,提出了使用人工地箭防治技术的注意事项,认为通过技术培训可以进一步提高捕获率。     

枣树病虫害无公害综合防治技术

采用无公害防治技术防治枣树病虫害,不仅可以提高枣产量,更重要的是可以提高枣的品质和经济价值。本文介绍的枣树病虫害无公害防治技术,适合吕梁山区红枣产区推广应用。     

歌诀在森防技术推广中的应用

本文介绍了歌诀在林业有害生物防治技术推广中的应用实例,从中可以看出,歌诀作为一种传统学习手段,可以广泛应用于林业有害生物的科普宣传、诊断与防治技术推广、森防文化的弘扬等诸多方面。     

The protective effects of Schisandra chinensis fruit extract and its lignans against cardiovascular disease: A review of the molecular mechanisms

Schisandra chinensis fruit extract (SCE) has traditionally been used as an oriental medicine for the treatment of various human diseases, including cardiovascular disease. Advances in scientific knowledge and analytical technologies provide opportunities for translational research involving S. chinensis; such research may contribute to future drug discovery. To date, emerging experimental evidence supports the therapeutic effects of the SCE or its bioactive lignan ingredients in cardiovascular disease, unraveling the mechanistic basis for their pharmacological actions. In the present review, we highlight SCE and its lignans as promising resources for the development of safe, effective, and multi-targeted agents against cardiovascular disease. Moreover, we offer novel insight into future challenges and perspective on S. chinensis research to future clinical investigations and healthcare strategies.     

番茄红素研究进展

番茄红素是类胡萝卜素中的一种,由于其在预防癌症和心血管等疾病方面有重要的作用,已成为国际上功能性食品研究的热点之一。本文综述了番茄红素的结构、性质、遗传背景、生物合成及其生理功能等方面的研究进展。     

反式脂肪酸的危害及其检测方法研究进展

反式脂肪酸是一种具有反式构型的不饱和脂肪酸,很多研究表明,反式脂肪酸对人体健康有一定危害,过多摄入导致心血管疾病、记忆力衰退,诱发妇女Ⅱ型糖尿病等。根据国内外研究动态对反式脂肪酸的研究现状进行了全面的综述,阐释了反式脂肪酸的结构、性质、食物来源及对人体的危害,并详细介绍了反式脂肪酸的检测方法。     

白藜芦醇研究进展

白藜芦醇具抗癌、抗心血管疾病、抗突变、抗菌、抗炎、抗氧化、诱导细胞凋亡及雌激素调节等多方面有益人类健康的生物药理活性;对植物来说,它是一种重要的植保素,能增强植株抵抗病原体的能力。因此,对白藜芦醇的研究引起了生物医学界工作者的高度重视。本文综述了近年来在白藜芦醇的分离纯化、含量测定、生物活性、芪合酶转基因方面的研究进展。     

Endothelium-dependent and -independent effect of aqueous extract of garlic on vascular reactivity on diabetic rats

Garlic has been well known for its protective effects against cardiovascular disease. In this study, the effect of aqueous extract of garlic on the vascular reactivity of thoracic aorta from streptozotocin (STZ)-diabetic rats was investigated in the presence and absence of endothelium. Although, 8-weeks of treatment with garlic extract had no significant effect on the concentration of serum glucose, but it significantly attenuated the abnormality in vascular reactivity to noradrenaline (NA) and acetylcholine (Ach). In addition, the endothelium-independent relaxation response to isosorbide dinitrate (ISD) was not affected by diabetes or garlic treatment. The results suggest that garlic treatment of STZ-diabetic rats can prevent the development of abnormal contractility through an endothelium-dependent and -independent mechanism.     

营养与衰老关系研究

指出了营养是人在整个生命过程中保持和提高健康状况的重要因素之一,营养的改善有助于降低慢性疾病的患病风险和延长寿命。研究发现卡路里限制能够延长一些生物的寿命,延迟衰老特征的产生,卡路里限制是通过调节表观遗传、细胞生长、衰老信号及细胞间传递信号分子来诱导细胞和整个机体水平上的衰老应答。适应性衰老应答可以使细胞和机体抗年龄有关的机体变化促进长寿。在人体中,卡路里限制能够抵抗癌症、糖尿病、动脉粥样硬化、心血管病和神经组织退化等慢性疾病的发生与发展从而促进人类的长寿。     

Anti-thrombotic activity and chemical characterization of steroidal saponins from Dioscorea zingiberensis C.H. Wright

Steroidal saponins have long attracted scientific attention, due to their structural diversity and significant biological activities. Total steroidal saponins (TSS) extracted from the rhizomes of Dioscorea zingiberensis C.H. Wright (DZW) constitute an effective treatment for cardiovascular disease. However, the active constituents contained in DZW rhizomes and their pharmacological properties are not fully understood. The aim of this work is to determine and quantify the active constituents in DZW rhizomes using fingerprint technique, and evaluate its anti-thrombotic activity using inferior vena cava ligation thrombosis rat model and pulmonary thrombosis mice model after being gavaged with TSS for 1 or 2 weeks. In the study, a chemical fingerprint method was firstly established and validated to quantify and standardize TSS from DZW rhizomes including parvifloside, protodeltonin, protodioscin, protogracillin, zingiberensis saponin, deltonin, dioscin and trillin. TSS extracted from DZW rhizomes were showed to have the inhibitions on platelet aggregation (PAG) and thrombosis, and prolong activated partial thromboplastin time (APTT), thrombin time (TT), and prothrombin time (PT) in a dose-dependent manner in rats. TSS also prolonged the bleeding time and clotting time in a dose-dependent manner in mice. The results indicate that TSS could inhibit thrombosis by both improving the anticoagulation activity and inhibiting PAG action, suggesting that TSS from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.     

Lipid-lowering effects of standardized extracts of Ilex paraguariensis in high-fat-diet rats

Mate (Ilex paraguariensis A. St.-Hil) is a native species of South America used to prepare traditional beverages. Recently a possible effect of its infusion on oxidative stress found in dyslipidemias has been reported. The main compounds related to these activities are phenolic compounds derived from chlorogenic acid. This study aimed to determine the anticholesteremic effect of the hydroethanolic extract (HEIP) and its n-butanolic fraction (n-BFIP), with standardized content of phenolic compounds derived from chlorogenic acid, in rats treated with high-fat diet (HFD). The contents of these compounds in the ethanol extract and n-butanol fraction were respectively two and three times higher than in traditional infusion with predominance of dicaffeoylquinic derivatives. The extracts were able to reduce serum triglycerides and cholesterol and decrease the atherogenic index in treated animals. These results support a potential effect of the mate extract in cardiovascular disease.     

Isorhynchophylline: A plant alkaloid with therapeutic potential for cardiovascular and central nervous system diseases

Uncaria species (Gouteng in Chinese) have been used as a plant medicine to treat ailments of cardiovascular and central nervous systems. As the main alkaloid constituent of Uncaria species, isorhynchophylline has drawn extensive attention toward antihypertensive and neuroprotective activities in recent years. Isorhynchophylline mainly acts on cardiovascular and central nervous systems diseases including hypertension, brachycardia, arrhythmia, and sedation, vascular dementia, and amnesia. Isorhynchophylline also has effects on anticoagulation, inhibition vascular smooth muscle cell apoptosis and proliferation, anti-multidrug resistant of lung cells, anti-endotoxemic, and antispasmodic. The active mechanisms are related to modulation on calcium ion channel, protection neural and neuroglial cells against β-amyloid(25-35)-induced neurotoxicity and via inducing autophagy. As a candidate drug of several cardiovascular and central nervous systems diseases, isorhynchophylline will attract scientists to pursue the potential related pharmacological effects and its mechanism with new technologies. But relatively few clinical application of isorhynchophylline has been conducted on its pharmacological activities. It requires more in vivo validations and further investigations of antihypertensive and neuroprotective mechanisms of isorhynchophylline.     

Evaluation and use of plant biodiversity for food and pharmaceuticals

Many epidemiological studies have shown the importance of fruit and vegetables in the human diet so as to prevent the onset of cardiovascular disease and several forms of cancer. The use for food and pharmaceuticals of two of the most widely grown and genetically well-known species in the world, the tomato and the potato, is reviewed. Tomatoes are important sources of vitamin C, potassium, folic acid and carotenoids such as lycopene and beta-carotene. It has been demonstrated that lycopene has anti-oxidant properties and interferes with the growth of cancerous cells. At the Department of Agronomy and Plant Genetics in Portici, interesting results have been obtained with the constitution of stable tomato hybrids having a high content of lycopene and vitamin C. Many of the parental lines used in constituting the hybrids come from interspecific crosses. Potato is also very important in the human diet for its content of high quality proteins, mineral salts and vitamins and it has many medicinal properties. The use of diploid wild species to transfer traits such as high content of vitamin C, mineral salts and high quality proteins into the cultivated potato through ploidy manipulation is discussed.