猪丹毒

丹毒是一种由红斑丹毒丝菌(Erysipelothrix rhusiopathiae)(图1)引起的传染病,常见于生长猪,特征性临床表现为猝死、发热、关节炎和皮肤损伤。丹毒可以分为急性、亚急性或慢性三种。虽然急性败血性猪丹毒能引发高死亡率,但最大的经济损失可能还是来自于慢性、非致命性丹毒。     

火鸡丹毒研究进展

火鸡丹毒是由红斑丹毒丝菌引起的一种火鸡的传染病。本文就其病原特性、发病机理、临床症状、病理变化、诊断及防治等方面的进展做一概述。     

Erysipelas as a disease factor

The infection with Erysipelas rhusiopathiae demonstrates that it is possible to characterize the significance of predisposing factors. The virulence of the agent is most important among the exogenous factors; it determines decisively the course of the disease: 1. paracute course as septicemia; 2. chronic course as polyarthritis; 3. subclinical course nearly without any symptoms. The immune status and the genotype of the host are predominant out of endogenous factors. The importance of immunity is known since a long time. A series of field observations supported the potential genetical influence in the pig. Within the hereditability an association to the MHC (in special genetic lines of rats to the RT 1 system of the MHC) was most recently determined in inbred laboratory animals. Additionally several environmental conditions, which can be summarized as stress, and as endogenous factor the age of the animals are relevant for the pathogenesis of the erysipelas infection. A non variable but most important disposition for special tissues are the so-called "borderline tissues", where accumulation, sedimentation and persistence of bacterial antigens are wellknown as described earlier. This phenomenon is determined by hemodynamic manifestation and quantifiably regulated by cytokines especially interleukin (IL 1) as well as by the tumor necrosis factor (TNF alpha) and prostaglandin PgE2. Additionally the cross reactivity of antibodies of Erysipelas rhusiopathiae against most specific collagen of type II, IX and XI in the pig and in laboratory animals was elaborated. This autoimmune phenomenon called "immunologic mimicry" supports besides the special physiologic conditions as niche of defense a very successful evolutionary adaptation of the agent.     

猪丹毒的诊治

[目的]为查清湖南湘潭市3个猪场疫情发生的原因。[方法]开展了流行病学调查和临床诊断、病理解剖、实验室检测。[结果]本次疫情共有3个养殖场的32头猪发病,其中育肥猪、架子猪、仔猪分别发病3头、26头、3头,发病率分别为：37.5%、8.67%、11.5%;死亡4头,其中架子猪3头、仔猪1头,死亡率分别是：1.0%、仔猪3.85%。[结论]最终确诊这3个场/户的猪只发生了猪丹毒疫情,并提出了综合性防治措施。     

生猪猪丹毒病临床诊断与防治

为加强猪丹毒病科学防治、促进生猪科学健康养殖,该文就猪丹毒病的流行特点、临床症状及病理变化进行具体介绍,提出有效的预防及治疗措施。