经阴道彩色多普勒超声对宫颈癌的诊断意义

目的总结经阴道彩色多普勒超声在宫颈癌诊断中的临床意义。方法应用GE-V730阴道探头对76例宫颈癌进行诊断,并与手术病理、CT扫描、膀胱镜和结肠镜检查进行对比分析。结果76例宫颈癌全部经病理证实。超声检出58例,检出率为76.3%。其中未检出18例宫颈癌中,有15例为早期浸润癌,另3例为浸润癌。超声检出癌组织未侵犯周围脏器43例,手术证实符合者42例(占97.7%);有癌组织侵犯周围脏器者15例,均经手术证实。经阴道彩色多普勒超声检查宫颈癌有典型的声像图特征。结论阴道彩色多普勒能诊断宫颈癌的准确性高,并能观察侵犯周围脏器的范围及程度,具有较高的应用价值;但对早期浸润癌的诊断则需依赖子宫颈刮片细胞学检查、子宫颈和宫颈管活组织检查、宫颈锥切术等手段。     

经颅超声辅助治疗急性脑梗死的临床观察

目的 观察经颅超声辅助治疗急性脑梗死的疗效及安全性.方法 将96例急性脑梗死患者随机分为2组,每组48例,对照组采用常规治疗,观察组除常规治疗外同时应用经颅多普勒寻找闭塞血管,使用经颅超声辅助治疗,疗程2周.对两组患者治疗前后的神经功能缺损及脑部血流动力学改变进行分析比较.结果 观察组总有效率93.8％,对照组总有效率...     

经颅超声辅助内镜下手术治疗高血压性丘脑出血的临床应用

目的探讨经颅超声辅助内镜下手术治疗高血压性丘脑出血的手术方法及临床疗效。方法回顾性分析30例高血压性丘脑出血患者的临床资料,符合诊断及手术标准,出血量20～50 mL,15例丘脑出血破入脑室,采用经颅超声辅助内镜经侧方清除血肿。结果全部病例术中超声精准定位血肿,准确率100%,15例出血破入脑室患者在超声监测下清除脑室内血肿。结论经颅超声辅助内镜下手术治疗高血压性丘脑出血具有定位精确、对脑损伤小、手术时间短、血肿清除率高的优点,可降低死亡率,提高患者生活质量,值得临床推广。     

经阴道与经腹部超声用于诊断早期宫外孕的比较

目的:分析腹部超声和阴道超声诊断早期宫外孕的准确性。方法:对116例诊断为早期宫外孕的病例进行回顾性分析,比较其经腹部或阴道超声的诊断符合率。结果:经腹部超声检查53例,诊断早期宫外孕22例,未检出31例,诊断符合率为41.5%;经阴道超声检查63例,诊断早期宫外孕57例,未检出6例,诊断符合率为90.5%。两者差异有统计学意义(χ2=31.772,P<0.01)。阴道超声未检出6例中,1例经三维成像技术诊断为间质部妊娠,腹腔镜证实2例为卵巢妊娠,2例为伞端妊娠,1例为峡部妊娠。结论:高分辨力的阴道超声检查在早期宫外孕的诊断中发挥了明显的优势。     

作业训练对脑梗死患者脑血流的影响

目的:观察作业训练对脑梗死患者大脑中动脉脑血流的影响,探讨脑梗死康复治疗的方法及效果评价。方法:选取医院住院治疗的脑梗死患者127例,按时间先后顺序分为康复组65例和对照组62例,并选择同期体检健康人81例作为健康对照组,康复组和对照规组在入院早期均按脑梗死常规处理,康复组在病情稳定后经康复师评价后采用作业训练康复治疗。康复组和对照组治疗前后均应用经颅超声多普勒(TCD)检测双侧大脑中动脉的平均血流速度(VD)。结果:治疗前康复组和对照组与健康组比较双侧大脑中动脉的血流速度显著降低(P0.01),康复组与对照组比较双侧大脑中动脉的血流速度无统计学差异(P0.05);治疗30d后康复组与健康组双侧大脑中动脉的血流速度无统计学差异(P0.05),康复组较治疗前增加(P0.01),较对照组明显增加(P0.01);对照组较治疗前明显增加(P0.05),但与健康组比较仍降低(P0.05)。结论:作业训练能够增加脑梗死患者损害区的脑血流量,促进功能恢复,TCD可以作为评价其早期疗效的指标。     

经腹超声与经阴道超声在早期异位妊娠诊断中应用分析

目的:探讨经腹超声与经阴道超声在早期异位妊娠诊断中的应用价值。方法:选择2013年1月至2015年12月医院收治的早期异位妊娠患者88例,所有患者均给予经腹超声与经阴道超声诊断,对比两种诊断方式的准确性、声像图效果。结果:经阴道超声诊断准确率为94.32%,明显高于经腹超声的76.14%,差异有统计学意义(P0.05);经阴道超声诊断声像图检查结果明显优于经腹超声(P0.0.5)。结论:经阴道超声在早期异位妊娠诊断中较经腹超声具有更明显的临床应用价值,诊断准确率更高,声像图效果更佳,可作为早期异位妊娠诊断的有效方法。     

彩色多普勒超声对早期高血压患者心脏及血管改变的诊断意义

目的评价彩色多普勒超声对早期高血压患者心脏及血管改变的诊断意义。方法应用彩色多普勒超声探测82例高血压患者及65例健康自愿者的心脏、颈动脉、肾动脉及大脑中动脉血流变化。结果高血压组心室间隔与左室后壁均增厚52例、左房扩大42例、二尖瓣口血流频谱E/A〈1者有72例、颈动脉内膜-中层增厚47例、颈动脉粥样硬化斑36例、肾段动脉阻力指数RI〉0.70者50例、大脑中动脉峰值流速〉106 cm/s者67例,而对照组分别为5、17、12、11、14、15、22例,两组差异均有统计学意义（P〈0.01）。高血压组心脏、颈动脉、肾动脉及大脑中动脉血流均出现异常表现者43例（52.4%）,对照组均无异常。结论彩色多普勒超声可了解早期高血压患者心脏结构、颈动脉内膜情况及肾动脉、脑动脉血流改变。     

经腹与经阴道彩色多普勒超声对宫颈肿物诊断的比较分析

目的 比较经腹及经阴道彩色多普勒超声对宫颈肿物的临床诊断.方法 对49例临床疑诊的宫颈肿物分别进行经腹部与经阴道彩色多普勒超声检查及宫颈细胞学病理检查和组织活检,对其结果进行分析.结果 49例宫颈肿物均经病理证实,经腹部彩色多普勒超声检查检出25例,漏诊24例,诊断率51.0 %(25/49),漏诊率49.0%(24/...     

应用超声多普勒检测仪对乳牛早期怀孕诊断试验

本试验采用SCDⅡ型兽用超声多普勒检测仪对483头乳牛进行了早期怀孕诊断,并与直肠检查法相比较,其符合率高。最早检出宫血音、胎心音、胎血音的时间分别为16天、50天、59天。宫血音诊断与直肠检查诊断的符合率在配种后16—30天、31—50天分别为92.93%（184/198）、97.91%（141/144）,在配种后51—79天及未怀孕的母牛均为100%（116/116及36/36）。胎血音在配种后59—65天、70—85天的符合率分别为48.15%（13/27）、90.35%（25/27）。试验证明,检测到宫血音的时间比胎心音、胎血音早30—40天左右,与直肠检查结果相比较其符合率也较高。因此,乳牛的早期怀孕诊断可用宫血音作为判定怀孕的主要依据。     

早熟葡萄新品种选育(Ⅰ)

“90 - 1”是从乍娜的芽变中选出的葡萄新品种。多年的研究试验表明 :该品种除保持母本的优质、丰产、适合保护地栽培等优良性状外 ,最突出的特点是极早熟 ,果实 6月下旬成熟 ,果实发育期 35d。果实不易感病 ,不宜用膨大剂处理。     

Purgatorius, an early paromomyid primate (Mammalia)

Fragmentary mandibles of Purgatorius unio Van Valen and Sloan from the Puercan (approximately early Paleocene), Garbani Locality, Montana, preserve associated postcanines. Their morphology indicates that this mammal was an early paromomyid primate and suggests that primate ancestry does not include currently known members of the palaeoryctid and leptictid Insectivora or of the Condylarthra.     

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

Cell-mediated (type-1) immunity is necessary for immune protection against most intracellular pathogens and, when excessive, can mediate organ-specific autoimmune destruction. Mice deficient in Eta-1 (also called osteopontin) gene expression have severely impaired type-1 immunity to viral infection [herpes simplex virus-type 1 (KOS strain)] and bacterial infection (Listeria monocytogenes) and do not develop sarcoid-type granulomas. Interleukin-12 (IL-12) and interferon-gamma production is diminished, and IL-10 production is increased. A phosphorylation-dependent interaction between the amino-terminal portion of Eta-1 and its integrin receptor stimulated IL-12 expression, whereas a phosphorylation-independent interaction with CD44 inhibited IL-10 expression. These findings identify Eta-1 as a key cytokine that sets the stage for efficient type-1 immune responses through differential regulation of macrophage IL-12 and IL-10 cytokine expression.     

Acetylcholine liberation from cerebral cortex during paradoxical (REM) sleep

The rate of liberation of free acetylcholine from the surface of prostigmin-treated cerebral cortex in the freely moving cat has been determined in states of slow wave sleep, paradoxical or activated sleep, and waking. The average rate during slow wave sleep (1.2 nanograms per minute per square centimeter of cortical surface) increased during paradoxical sleep (2.2 nanograms per minute) and during waking (2.1 nanograms per minute). The rate of acetylcholine release is thus related to the electroencephalogram pattern of desynchronized activatin of the cortex rahter than to the behavioral responsiveness of the animals.     

鳗鲡胚胎和早期仔鱼的耗氧量

测定了鳗鲡人工繁殖的胚胎６个主要发育期的耗氧量。总的变化趋势是随着胚胎发育时间的延长,耗氧量也在逐渐增加,二者裼 相关符合指数函数Ｙ＝０．１２４２ｅ＾０．０３９２。其中原肠期和出膜期是对水中溶氧量特别敏感的时期。同时,测定了早期仔鳗（孵出后１～４ｄ）生长耗氧量,并对胚胎及仔鳗的耗氧特点作了初步的讨论。     

鳗鲡胚胎和早期仔鱼的耗氧量

测定了鳗鲡人工繁殖的胚胎 6个主要发育期的耗氧量。总的变化趋势是随着胚胎发育时间的延长 ,耗氧量也在逐渐增加 ,二者之间的相关符合指数函数Y =0 1 2 4 2e0 0 392t。其中原肠期和出膜期是对水中溶氧量特别敏感的时期。同时 ,测定了早期仔鳗 (孵出后 1～ 4d)生长的耗氧量 ,并对胚胎及仔鳗的耗氧特点作了初步的讨论     

Evidence for lignin-like constituents in early silurian (llandoverian) plant fossils

Chemical evidence is presented with previously reported morphological features for banded-tube cell types in the earliest known plant fossils associated with stream-deposited sediments. Phenolic aldehydes (p-hydroxybenzaldehyde, vanillin) and aromatic compounds from pyrolysis (2-methoxy-4-hydroxybenzaldehyde, methylsyringaldehyde) derived from cellular remains are interpreted as evidence for lignin or lignin-like degradation products. The presence of parallel-aligned banded tubes, with annular to spiral thickenings and occasional end walls, in conjunction with lignin-like constituents fulfill most of the morphological and chemical criteria for cell types that could have functioned as water-conducting cells.     

肉牛早孕因子（EPF）的活性检测及分离纯化

【目的】检测怀孕肉牛早孕因子(Early pregnancy factor,EPF)的活性,并对其进行分离纯化,以期为EPF快速检测方法的建立提供依据。【方法】采集妊娠1~9个月的肉牛血样,并进行妊娠诊断,通过玫瑰花环抑制试验(Rosette inhibition test,RIT)检测其早孕因子的活性。对有活性的血样依次进行DEAE-52离子交换层析、ConASepharose 4B亲和层析和Heparin Sepharose Cl 6B亲和层析,分离纯化EPF,对纯化产物进行SDS-PAGE检测,并测定其等电点。【结果】怀孕牛和未怀孕牛血清的玫瑰花环抑制滴度差异显著(P<0.05)。玫瑰花环抑制试验显示,纯化出的EPF具有活性,其分子质量为53.6 ku,等电点为6.8。【结论】利用玫瑰花环抑制试验检测早孕因子活性,可以鉴定肉牛的妊娠状态;利用层析的方法可以分离出早孕因子的活性蛋白。     

Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)

Human hereditary cerebral hemorrhage with amyloidosis of the Dutch type (HCHWA-D), an autosomal dominant form of cerebral amyloid angiopathy (CAA), is characterized by extensive amyloid deposition in the small leptomeningeal arteries and cortical arterioles, which lead to an early death of those afflicted in their fifth or sixth decade. Immunohistochemical and biochemical studies have indicated that the amyloid subunit in HCHWA-D is antigenically related to and homologous in sequence with the amyloid beta protein isolated from brains of patients with Alzheimer's disease and Down syndrome. The amyloid beta protein is encoded by the amyloid beta protein precursor (APP) gene located on chromosome 21. Restriction fragment length polymorphisms detected by the APP gene were used to examine whether this gene is a candidate for the genetic defect in HCHWA-D. The data indicate that the APP gene is tightly linked to HCHWA-D and therefore, in contrast to familial Alzheimer's disease, cannot be excluded as the site of mutation in HCHWA-D.