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Addison's disease in the dog 总被引:1,自引:0,他引:1
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Williams M Olver C Thrall MA 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2006,35(4):471-473
A 4-month-old, intact male Boxer puppy was presented to the Animal Emergency and Critical Care Services of South Florida because of nasal discharge, dehydration, dyspnea, and coughing. The dog had been diagnosed with intestinal parasites and kennel cough approximately 10 days before presentation. Lateral and ventrodorsal radiographs of the thorax revealed an increased bronchointerstitial pattern throughout the lungs. A transtracheal wash was performed. On cytologic examination of direct, Wright-Giemsa-stained smears, small basophilic coccoid structures (0.3-0.9 microm in diameter) were observed in low to moderate numbers within neutrophils and adherent to epithelial cells. The small size of the organisms raised suspicion for Mycoplasma. Culture of the transtracheal wash fluid resulted in growth of a Mycoplasma sp. The patient was treated with enrofloxacin and amoxicillin/clavulanate and made a full recovery. Recognizing Mycoplasma in transtracheal washes could aid in recommending the appropriate culture media or immunologic techniques, which could result in an accurate diagnosis of mycoplasmosis. 相似文献
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N. J. Dickson 《The Journal of small animal practice》1990,31(2):105-108
Primary cold agglutinin disease is an autoimmune disease seen in the dog and man. A case of cold agglutinin disease is described in a puppy which was undergoing treatment for lead intoxication. 相似文献
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P. H. Kook P. Grest U. Raute-Kreinsen C. Leo C. E. Reusch 《The Journal of small animal practice》2010,51(6):333-336
A 12-year-old Rottweiler cross Labrador was presented with anorexia and weakness. Adrenal insufficiency was diagnosed with hyponatraemia, hyperkalaemia and undetectable resting and post-ACTH cortisol and aldosterone concentrations. The only abnormal diagnostic imaging result was bilateral adrenomegaly. Cytologic findings of liver, spleen and peripheral lymph nodes were normal. The dog responded initially to standard replacement therapy but relapsed shortly afterwards. The owners opted for euthanasia and allowed only removal of both adrenal glands. Microscopically, infiltrative polymorphic proliferations of densely packed tumour cells arranged as nests, intermingled with multifocal areas of necrosis and inflammatory cells were found. Silver staining revealed a few non-neoplastic adrenomedullary cells, whereas neoplastic cells did not stain. Immunohistochemistry was negative for neuron-specific enolase, vimentin, cytokeratin, synaptophysin, chromogranin A, S-100 protein, CD 56, 79 and 3. The final diagnosis was highly anaplastic bilateral adrenal neoplasia. This is the first report of bilateral adrenal malignancy presenting as clinical hypoadrenocorticism in a dog. 相似文献
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Burgess H Ruotsalo K Peregrine AS Hanselman B Abrams-Ogg A 《The Canadian veterinary journal. La revue veterinaire canadienne》2008,49(4):389-392
A 4-year-old, standard poodle was presented to the Ontario Veterinary College for a 3-week history of a moist, productive cough that was first noted while boarding at a kennel. Bronchoalveolar lavage revealed numerous ova identified as Eucoleus aerophilus, previously known as Capillaria aerophila. Clinical signs resolved following treatment with fenbendazole. 相似文献
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Abstract Extract Hypoadrenocorticism, or Addison's disease, is an uncommon en-docrinopathy of dogs (Feldman and Nelson 2004). Long-term management of affected dogs in New Zealand involves treatment with oral fludrocortisone acetate (Florinef tablets; Bristol-Myers Squibb (NZ) Ltd, Auckland, NZ), which is a relatively expensive synthetic adrenocortical steroid. Table salt may be added to the food, in an attempt to reduce the amount of fludrocortisone required. Despite fludrocortisone therapy, many Addisonian dogs remain hyponatraemic and hyperkalaemic and the required dose of fludrocortisone may need to be increased during the first year of treatment. Increasing the dose of fludrocortisone is not only expensive, but may also have undesirable effects through its potent glucocorticoid action. 相似文献
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An 8-week-old, male Labrador retriever presented for acute onset of left hind limb lameness. This rapidly progressed to juvenile cellulitis, characterized by dermatitis of the face, otitis externa, regional lymphadenopathy, lethargy, and depression. The puppy made a full recovery on glucocorticoid therapy. 相似文献
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I. P. Boydell 《The Journal of small animal practice》1998,39(9):448-449
A puppy was presented with unilateral Horner's syndrome thought to have been in existence since the eyes first opened. No other clinical signs were evident and the condition was attributed to trauma during assisted birth. All abnormalities resolved spontaneously by 11 weeks of age. 相似文献
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V. Luis Fuentes K. J. Long P. G. G. Darke A. G. Burnie 《The Journal of small animal practice》1991,32(11):585-588
An eight-week-old female Cavalier King Charles spaniel was presented with tachypnoea, pyrexia and distended jugular veins following bite injuries to the chest and abdomen. Pericardial effusion was suspected from clinical, electrocardiographic and radiographic findings, and confirmed by echocardiography. Pericardiocentesis was carried out and the purulent fluid aspirated yielded Pasteurella multocida on culture. After drainage, broad spectrum antibiotic therapy was instituted and the puppy went on to make an excellent clinical recovery. Despite this, some hyperechoic areas of myocardium were observed on echocardiography and occasional ventricular premature complexes were seen on electrocardiography. These were probably the result of an associated myocarditis. 相似文献
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Gastrointestinal cryptosporidiosis in a puppy 总被引:2,自引:0,他引:2
An 8-week-old female Yorkshire terrier with a history of weakness, diarrhea and intestinal isosporiasis was euthanized and a post mortem examination performed. Histologically, there was severe gastrointestinal cryptosporidiosis, severe intestinal isosporiasis and thymic lymphoid depletion. PCR revealed visible bands for the actin and 18S rRNA genes but not for the acetyl CoA synthetase gene for Cryptosporidium spp. The PCR product for the actin gene was sequenced and found to have a 97.6-99.8% similarity to that of Cryptosporidium canis. To our knowledge, this is the first report of gastric cryptosporidiosis in a canine. 相似文献
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Huerter L 《The Canadian veterinary journal. La revue veterinaire canadienne》2000,41(7):565-567
After showing clinical and radiographic signs of a gastrointestinal foreign body, a 5-month-old puppy began head pressing, which progressed to convulsions. Hematological abnormalities suggested lead poisoning; serum lead was 2.61 mumol/L. The puppy made a complete recovery after intensive treatment for lead toxicosis. 相似文献
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Craniomandibular osteopathy in a labrador puppy 总被引:3,自引:0,他引:3
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G. L. Walmsley K. Chandler E. S. Davies C. R. Lamb B. Smyth B. A. Summers 《The Journal of small animal practice》2009,50(8):435-439
A nine-month-old puppy was presented for investigation of seizures. Neurological deficits were found localising to the prosencephalon, mesencephalon and myelencephalon. Magnetic resonance imaging identified multiple, large lesions involving both cerebral hemispheres. Management with antiepileptic and immunomodulatory drugs was instituted; however, the seizures became progressively refractory and the puppy was euthanased. Histopathology following post-mortem examination found a mixed glial cell tumour with discrete areas where neoplastic cells appeared oligodendroglial or astrocytic. Primary intracranial neoplasia is a rare cause of neurological disease in young dogs. Moreover, this case is unusual in terms of both the mixed glial nature of the neoplasm and also its multi-focal distribution. 相似文献
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White J Taylor SM Wolfram KL O'Conner BP 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(9):931-934
A 10-week-old, male, border collie-cross puppy was examined for an acute onset of unilateral vestibular signs. Neurologic deterioration was rapid over the next 12 hours and the puppy was euthanized. Rabies was diagnosed by histopathologic and immunohistochemical examination. 相似文献