猪伪结核耶新氏杆菌病

1993～ 1998年 ,我们在猪屠宰加工厂和一些饲养单位的检验和检疫中 ,发现猪有猪伪结核病变 ,并从有病变的脾脏和肠系膜淋巴结等器官分离到细菌 ,经东北农业大学鉴定属于耶新氏杆菌属中的伪结核耶新氏杆菌。所分离的菌株经抗原型鉴定属于 4个不同菌体抗原型。从 4个不同抗原型中     

Yersinia pseudotuberculosis in the cat.

Yersinia pseudotuberculosis infection in the cat is described. Clinical findings included inappetence, lethargy, rapid emaciation, jaundice and an enlarged left kidney. Chronic pseudotubercular lesions were found in the kidneys and lungs and Yersinia pseudotuberculosis Type IIB was recovered from both sites.     

Yersinia pseudotuberculosis Infection in a Cat

A diagnosis of Yersinia pseudotuberculosis in a cat was established by microbiological and histological means. Clinical signs were general malaise, anorexia and vomition. Significant laboratory findings included a serum glutamicpyruvic transaminase elevation and the presence of urine bilirubin and urobilinogen. Histological examination of liver biopsies revealed numerous varying-sized foci of caseation necrosis containing large numbers of Gram-negative coccobacilli. Bacteriological techniques, treatment and control measures are discussed.     

Yersinia pseudotuberculosis in New World monkeys

It is reported on four cases of pseudotuberculosis in 2 Saimiri sciureus, 1 Callithrix jacchus/penicillata hybrid and 1 S. oedipus. The animals came from two different groups, one being infected with Y. pseudotuberculosis serotype I, the other with Y. pseudotuberculosis serotype II. All cases showed intestinal infection of thermophile Campylobacter. Remarkable were severe haemorrhagic components and the distinct RHS-proliferation, especially in the mesenteric lymphatic nodes.     

Enteritis in cattle due to Yersinia pseudotuberculosis infection

A selective medium was used to isolate Yersinia sp from the intestinal tract of 222 scouring cattle in Gippsland during 1985 and 1986. Intestinal infection with Y. pseudotuberculosis, particularly of serotype III, was found to be especially prevalent in weaned calves, yearlings and young adult cattle. Clinically affected cattle had a profuse liquid diarrhoea and many were systemically ill. Haematological changes suggestive of infection were present in 38 of 49 of these cattle. At least 35 cattle died and characteristic microabscesses were demonstrated in the intestinal mucosa of 20 of 26 examined histologically. Y. pseudotuberculosis was sensitive to tetracyclines in vitro and this drug produced a rapid bacteriological cure. Yersiniosis occurred during the winter, spring and early summer. Challenge of adult cattle with Y. pseudotuberculosis serotype III did not result in intestinal colonisation or clinical disease. Intestinal infection was, however, established in 4 weaned calves and haematological changes and antibody production were demonstrated in them. Intestinal microabscesses were seen in three calves killed on days 8, 14 and 18 after challenge. The fourth calf eliminated infection by day 18 and no lesions were demonstrated when it was killed on day 72. There is a very high prevalence of antibodies reacting with Y. pseudotuberculosis serotype III in adult cattle. It is concluded that cattle are a common host for this bacterium, infection being frequent, with clinical and fatal disease occurring occasionally. The factors leading to clinical disease are unknown.     

Mastitis caused by Yersinia pseudotuberculosis in a cow

Subclinical mastitis with a raised somatic cell count was diagnosed in a cow in her fifth lactation. It was caused by Yersinia pseudotuberculosis, which can also infect humans. This is the first time that Yersinia pseudotuberculosis has been isolated from a mastitis sample in The Netherlands. Despite treatment with antibiotics in the dry period, Yersinia pseudotuberculosis was still present in the same quarter in the subsequent lactation. The somatic cell count was still high and milk production was much lower than in previous lactation. The pathogen did not spread to other quarters of the same cow or to herd mates on the farm over a 1-year period.     

Enterocolitis in cattle associated with Yersinia pseudotuberculosis infection

A syndrome in cattle of diarrhoea and death associated with enteric Yersinia pseudotuberculosis infection is described. Outbreaks occurred during winter and early spring in adult cattle grazing pastures waterlogged by recent flooding or persistent heavy rain. Antibiotic therapy was effective early in the course of the syndrome. At necropsy there was severe acute enterocolitis, and bacteria consistent with Y. pseudotuberculosis were observed in the lesions. This organism could usually be isolated from the intestines of affected animals but was recovered less often from other organs. Representative isolates were identified as Y. pseudotuberculosis serotype III. The association of this syndrome with waterlogged pastures and low temperatures suggests that these conditions favour transmission of Y. pseudotuberculosis infection in cattle. The role of Y. pseudotuberculosis as primary pathogen requires confirmation.     

Growth of Yersinia pseudotuberculosis on selective media

As a prelude to experiments designed to evaluate the growth of Yersinia pseudotuberculosis on frozen vacuum-packed venison, we wished to assess the sensitivity of the commonly used selective medium, Yersinia selective agar (YSA) with the added antibiotics cefsu- lodin, irgasan and novobiocin (CIN agar), for recovery and enumeration of this organism⁽¹⁾.     

Caprine enteritis associated with Yersinia pseudotuberculosis infection

Yersiniosis was prevalent among a caprine herd during the late autumn of 2003 in Iwate Prefecture, Japan. The disease affected 29 of about 100 lactating goats, but not dried or nonparous goats, mature male goats or kids. Four animals died within an epidemic period of 20 days. Affected animals developed decreased milk production with subsequent watery diarrhea, neutrophilia with increased band forms and multiple microabscesses characteristic of yersiniosis in the intestinal mucosa from the jejunum to caecum as well as in the mesenteric lymph nodes. Y. pseudotuberculosis serotype III was isolated from intestinal contents and mesenteric lymph nodes. The organism was also cultured from clinically normal dried animals. The outbreak might have been precipitated by multiple stress factors, such as lactation, cold weather, Corynebacterium pseudotuberculosis infection resulting in abscess formation and tapeworm and coccidium parasitisms.