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1.
Tiamulin {14-deoxy-14[(2-diethylaminoethyl)-mercaptoacetoxy]-mutilin} hydrogen fuma-rate is a semisynthetic antibiotic. It is clinically effective against pathogenic mycoplasma organisms, e.g. Treponema hyodysenteriae , a large number of Gram-positive and some Gram-negative organisms (Drews et al. , 1975). Tiamulin has been shown, under controlled laboratory conditions (Laber & Schutze, 1975; Baughn et al. , 1978) and against natural infection under field conditions (Stipkovits et al. , 1977), to control respiratory tract infections effectively involving Mycoplasma galliseptkum in chickens and turkeys. It has also been demonstrated that tiamulin could be used as an aid in the control of avian coccidiosis produced by Eimeria acervulina and E. tenella in broilers chickens (Cruthers et al. , 1980).  相似文献   

2.
Evidence of a specific dietary selection for lysine by the piglet   总被引:4,自引:0,他引:4  
The ability of animals to appropriate sources of food and select among them to obtain a nutritionally adequate diet that is best suited for their physiologic status has been examined in numerous species, but considerable research has addressed self-selection trials with chicks. Observations on diet preference have led to the assumption that birds have an innate ability to regulate their intake of macro- and micronutrients, and that they can do so with a considerable degree of precision (e.g. Holcombe et al. 1975, 1976; Elkin et al. 1985; Harper and Peters 1989; Emmerson et al. 1991; Steinruck et al. 1991a,b; Steinruck and Kirchgessner 1993a,b,c; Shariatmadari and Forbes 1993; Forbes and Shariatmadari 1994, 1996). Experimental evidence also shows that domesticated pigs which are offered a choice between two diets will select a diet containing an adequate amount of protein in preference to one that is deficient in protein, or will select specific proteins among various protein sources (Robinson 1974; Kyriazakis et al. 1990; Kyriazakis and Emmans 1992, 1993; Bradford and Gous 1992; Roberts and Azain 1997). The characteristic amount of a specific protein selected by the animals appeared to be related to the quality of the protein source. This was obvious from a few amino acid selection studies showing that growing-finishing pigs have the ability to select preferentially amino acid-adequate diets over amino acid-deficient diets within a few days (Devilat et al. 1970; Robinson 1975a,b; Davey 1978; Henry 1987, 1993). In contrast, there are also some exceptions to the hypothesis that selection of diet is related to the nutritional quality of the protein fed (Ashley and Anderson 1975). However, some of those studies are not conclusive due to changes in preferences by the animals over time and differences in protein source, palatability and amino acid pattern between the test diets. Since, an investigation of a self-selection behaviour by piglets has rarely been studied in detail, the purpose of this research was to determine whether piglets that are given a choice of diets with high or low lysine contents can regulate the intake of each to optimize lysine intake and performance. The objectives of this study were to determine the preference of piglets for diets varying in lysine content and to determine whether the preferences for these diets change with time. This indispensable amino acid was selected for study because it is first limiting in conventional diets for growing pigs.  相似文献   

3.
Eggs from the pig roundworm Ascaris suum are easily obtainable in large numbers from uterus of adult worms. It is therefore natural that eggs isolated from that organ have been used almost exclusively in experimental ascariasis, both in the natural host (Kelley & Nayak 1965, Gaafar & Keittevuti 1972, Andersen et al. 1973, Jørgensen et al. 1975 and others) and in small laboratory animals (Jeska et al. 1969, Berger 1971 and others). In some cases no details are given on the origin and preparation of the infective eggs or the eggs may originate both from uteri of adult worms and from pig faeces (Kelley et al. 1957).  相似文献   

4.
High-altitude grazing, at or above the timberline in summer months continues to be important in alpine regions of Europe, where about 80% of young stock spend much of the three summer months on these pastures. Apart from direct utilization of these resources and saving of feed in the home farms, alped cattle are said to have greater longevity and better growth, i.e. they display compensatory growth. K& uuml ; nzi et al. (1988), S uttner (1980) and R uhland (1983) reported that heifers which spent one or two summers on alpine pastures, have, as cows in intra-herd comparisons, about one lactation more than homegrown heifers. Compensatory growth after alpage was reported by these authors, by B ianca (1977), W eilenmann -B ossart (1988) and other authors. The effects of alpine sojourn on physiological and biochemical traits were investigated by B ianca and E spinosa (1975), B ossart et al. (loc. cit.), K rippl et al. (1961) and S uttner (1980). This investigation concerns the comparative effects of alpine pasture and farm feeding on subsequent physiological and biochemical traits.  相似文献   

5.
Porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is a major problem in modern swine industry worldwide. At present 12 serotypes have been recognized (Nielsen 1990). Serotyping has been based upon capsule associated, heat-stabile antigens of polysaccharide (PS) and lipopolysaccharide (LPS) nature. A variety of tests have been used for serotyping including slide agglutination (Mittal et al. 1982), immunodiffusion (Gunnarsson et al. 1978, Nielsen & O’Connor 1984), indirect haemagglutination (Mittal et al. 1983a) and coagglutination (Mittal et al. 1983b). Recent studies report on serotyping of A. pleuropneumoniae strains using monoclonal antibodies in enzyme-linked immunosorbent assays (Lida et al. 1990, Nakai et al. 1990).  相似文献   

6.
Several successful attempts have been made to induce swine dysentery in pigs using pure cultures of Treponema hyodysen-teriae (Taylor & Alexander 1971, Harris et al. 1972, Akkermans & Pomper 1973, Hughes et al. 1975). In these studies, either conventional or specific-pathogen-free pigs were used. In the present study, 2 approximately 8 weeks old conventional pigs (Nos. 1 and 2) were purchased and fed the same basic ration as used by Teige et al. (1977). In addition, 10 % cod liver oil was incorporated in the diet at each feeding. After a feeding period of 25 days rectal swabs were applied and examined for the presence of spirochaetes. The pigs were then fed a 3 days old primary and pure culture of T. hyodysenteriae on TSA-S400 medium (Songer et al. 1976). The culture originated from the colon of a pig with swine dysentery (Pig No. 4, Teige et al. 1977). Each pig received the agar contents of 5 petri dishes which were mixed with the food.  相似文献   

7.
Bovine respiratory syncytial virus (BRSV) caused a large epizootic of acute respiratory disease in Japan in 1968—69 (Inaba et al. 1970, Inaba et al. 1972). A much smaller outbreak occurred in Switzerland (Paccaud & Jacquier 1970). In Belgium the virus has been isolated from an outbreak of respiratory disease (Wellemans et al. 1970). BRSV has later been proved an important causal agent of respiratory disorders in the same country (Wellemans & Leiinen 1975). In England and USA the virus has caused and been isolated from outbreaks of acute respiratory disease in calves (Jacobs & Edington 1971, Rosenquist 1974, Smith et al. 1974). In Denmark BRSV has sporadically been isolated from pneumonic calf lungs (Bitsch et al. 1976).  相似文献   

8.
Introduction   Competition and aggression in pigs is known to reduce daily weight gain (DWG) (R und GREN and L& ouml ; fqvist 1989; H yun et al. 1998; L und et al. 1998), and to impair feed conversion ratio (W alker 1991; L und et al. 1998). The exact biological mechanisms behind these effects are not fully understood. Aggression and competition activate a cascade of reactions of biological relevance, such as inhibition of the parasympathetic nervous system, stimulation of the sympathetic nervous system, including the adrenal medulla (A xelrod et al. 1970; D alin et al. 1993a, 1993b), and activation of the hypothalamo-hypophyseal-adrenal (HHA) axis resulting in higher adrenocorticotropic hormone (ACTH) and higher cortisol concentrations in the plasma (D alin et al. 1993b; O lsson and S vendsen 1997). These responses as well as muscular activity increase metabolic losses (S chrama et al. 1993).
Hyper-physiological treatment with glucocorticoids stimulates pancreatic amylase activities in piglets (B aintner and N emeth 1982; C happle et al. 1989a, 1989b, 1989c), but no observations in growing pigs have been published. Inhibition of the parasympathetic nervous system (C hey et al. 1979) and stimulation of the sympathetic nervous system (C hey 1991) reduce exocrine pancreatic secretion. So, there might be some conflicting physiological responses of the exocrine pancreas to stress conditions. In order to increase our understanding of the animal's physiological responses to conditions of stress, we tested the hypothesis that conditions associated with stress (mixing with unfamiliar pigs, frustration and ACTH treatment) reduce exocrine pancreatic secretion. In addition, we tested the effect of treatment with Amperozide (a neurolepticum which reduces aggression and the effects of stress in pigs) on exocrine pancreatic secretion.  相似文献   

9.
In laboratory animals, dietary cholesterol has been shown to cause increased levels of lipids in plasma and liver, and additionally markedly raises liver weights (Lee and Ho 1975; Huang et al. 1984; Stangl et al. 1994). In poultry, similar studies dealing with the effects of cholesterol are lacking. An effect of cholesterol on liver weights could be of particular interest in geese since the production of fatty livers ('Foie gras') by force-feeding techniques is common in some countries. Therefore, a previous study (Eder 1999) was concerned with the effects of feeding cholesterol on concentrations of various lipids in liver, plasma and muscle. This study demonstrated that dietary cholesterol has profound effects on lipid concentrations in liver, plasma and even in the muscle of geese which were additionally amplified by feeding cholic acid. This study was performed to investigate whether an accumulation of cholesterol in tissues also affects the metabolism of fatty acids. This question was of particular interest because it is known that both, cholesterol and fatty acids are constituents of membranes influencing important membrane properties such as fluidity, permeability or the activity of membrane-bound enzymes (Stubbs and Smith 1984). In order to clarify that question, the fatty acid composition was analysed in various tissues of geese that had been fed diets with cholesterol and/or cholic acid.  相似文献   

10.
11.
Feline immunodeficiency virus (FIV), previously known as feline T-lymphotropic lentivirus (FTLV), was first described by Pedersen et al. (1987) who isolated the virus from cats with a variety of clinical signs suggestive of immunodeficiency. Since then FIV has become one of the most studied feline viruses, not least because of its similarity to human immunodeficiency viruses (HIV) which cause acquired immunodeficiency syndrome (AIDS) in man.  相似文献   

12.
During the last decade, an increasing number of bovine adenoviruses have been isolated from calves suffering from more, or less, well-defined syndromes. These have consisted of respiratory disorders of varying severity, enteritis, or a combination of both, which in typical cases has been termed “pneumo-enteritis”. These investigations have been reviewed by Darbyshire (1968). Wilcox (1969) isolated adenoviruses from kerato-conjunctivitis (KC) in cattle. Furthermore, strains have been isolated from apparently healthy animals (Darbyshire 1968), and from tissue cultures prepared from various organs from calves such as kidneys (Scho- pov et al. 1968), and testes (Rondhuis 1968, Bartha & Csontos 1969). At the present time 9 serotypes of bovine adenoviruses exist, as determined by neutralization tests, and these have recently been reviewed by Guenov et al. (1970). However, several strains, some from cases of pneumonia (Cole 1970, Lupini et al. 1970) and others from KC (Wilcox 1969) remain to be typed and compared with the known prototypes, thereby enabling possible new serotypes to be identified. So far, serotypes 1 and 2 (Darbyshire et al. 1969), serotype 3 (Darbyshire et al. 1966) and serotypes 4 and 5 (Aldasy et al. 1965) have been shown to cause pneumo-enteritis, and serotype 6 (Rondhuis 1970) a mild respiratory disease in experimentally infected calves. Similarly, KC has been produced experimentally by Wilcox (1970), while the pathogenicity for experimental animals of the other typed and untyped strains remains to be investigated.  相似文献   

13.
Y-chromosomal loci are genetically responsible for some male-specific biological processes. The sex determining region Y (SRY), a protein with DNA-binding activity, is known as the trigger for sex differentiation in mammals. In humans the SRY is encoded by a single exon located on the short arm of the Y chromosome, close to the pseudoautosomal boundary (S inclair et al. 1990). Moreover, the Y chromosome harbours the male-specific histocompatibility antigen (reviewed by S impson et al. 1997) and there are at least two regions of the Y chromosome, which have been shown to be essential for normal spermatogenesis in mice (E lliott and C ooke 1997). The sexual dimorphism of aggression in mice has led to a search for its foundation on the Y chromosome. The existence of Y-chromosomal genetic variation for aggressiveness with genetic factors borne both on the pseudoautosomal (YPAR) and on the nonpseudoautosomal (YNPAR) region of the Y chromosome (S luyter et al. 1996) has been shown. Another example for Y-induced genetic variation in mice is the testis autosomal trait (occurrence of ovaries or ovotestes in XY animals), which is observed when specific Y chromosomes interact with the autosomal background of certain laboratory mouse lines (E isner et al. 1996). A comparison of the resemblance of different types of relatives indicated a nonzero Y-chromosomal variance for body weight in mice (B& uuml ; nger et al. 1995). In cattle the Y chromosomes of the Bos taurus and Bos indicus subspecies can be morphologically distinguished: its shape is submetacentric in B. taurus and acrocentric in B.indicus. This difference is caused by a pericentric inversion (G oldammer et al. 1997) and has frequently been used to investigate the introgression of zebu genes into B. taurus breeds. The polymorphism of the bovine Y chromosome itself and the results of mouse research both direct the scientific curiosity on the possible contribution of the bovine Y chromosome to quantitative genetic variation in cattle, a question which, to the authors’ knowledge, has not been investigated before. In this paper we first discuss the contribution of autosomal, imprinted, and sex-linked genes to the resemblance of full and half sibs and then present a Bayesian estimation of a Y-chromosomal variance component for each of four beef traits in young Simmental bulls using mixed linear and threshold models.  相似文献   

14.
Infectious pancreatic necrosis (IPN) is a disease of salmonid fishes. It has been reported in many countries throughout the world (MGonigle 1940, Wood et al. 1955, Besse & Kinkelin 1965, Vestergård Jørgensen & Bregnballe 1969, Sano 1971, Ball et al 1971, Ljungberg & Vestergård Jørgensen 1972, Schlotfeldt et al. 1975). Outbreaks of the disease can cause serious losses in populations of hatchery reared salmonids, the mortality rate varying between 10 and 90 % (Vestergård Jørgensen & Kehlet 1971). There are at least four different serotypes of the virus distinguished by neutralization tests (Wolf et al. 1968). Twenty-five isolates of IPN virus in Denmark proved to represent only two serotypes (Sp and Ab) (Vestergård Jørgensen & Kehlet). The present paper reports the first isolation of IPN virus from the stock at a fish farm in Norway.  相似文献   

15.
Porcine toxoplasmosis generally occurs as a latent disease in adolescent and adult pigs, but now and then also manifests itself as a fatal congenital disease in piglets. It is known to occur in USA (Farrel et al. 1952), Germany (Becker 1954), Denmark (Momberg-Jørgensen 1956), Mexico (Varela et al. 1956), Japan (Sato et al. 1958), England (Harding et al. 1961) and Sweden (Hansen et al. to be published).  相似文献   

16.
Introduction Indirect calorimetry based on measurements of gas exchange has been used successfully during the last century in order to estimate energetic values of feedstuffs and animals’ requirement for nutrients and energy. Recently, measurements of gas exchange have been used to calculate nutrient oxidation and lipogenesis in the intact body of man (T horbek et al. 1994), pigs (C hwalibog et al. 1992; C hwalibog and T horbek 1995), calves (C hwalibog et al. 1996; C hwalibog et al. 1997a), mink (T auson et al. 1997) and rats (C hwalibog et al. 1998). In the present paper a similar approach has been used to quantify nutrient metabolism in laying hens in accordance with a calculation method first proposed by C hwalibog et al. (1992) and later modified as outlined in Fig. 1. According to this biological model digested protein (DP) which is equal to PROT group is utilized for retention in eggs (OP), ovary and body (OBP), whereas deaminated amino acids are oxidized (OXP) with concomitant excretion of energy with nitrogenous substances in urine (UEN) and contribution of energy (GLUC) to carbohydrate metabolism. Digested carbohydrate (DCHO) together with GLUC constitute the CHO group, which is retained in eggs (OCHO), oxidized (OXCHO) and used for lipogenesis (LIPO). Digested fat (DFAT) and lipids from lipogenesis constitute the FAT group, which is incorporated into eggs (OF), ovary + body (OBF) and oxidized (OXF). Both CHO and FAT metabolism contribute with energy containing products excreted with urine (UEN-free). The energy from OXP, OXCHO and OXF make up the total heat production (HE). The validity of the method will be discussed later. The aim of this study was to demonstrate how data from gas exchange measurements in combination with nitrogen and energy balances can be applied in order to calculate nutrient oxidation and the quantities of substrates used for retention and lipogenesis processes, and furthermore, to elucidate differences in nutrient oxidation and lipogenesis in relation to different housing conditions and genotypes of laying hens.  相似文献   

17.
Streptococcus suis is an important pig pathogen which is associated with respiratory problems, meningitis and less fre-quently with a variety of other conditions(Hommez et al. 1986). S. suis type 1 causes disease mainly in 1–2 week old pigs while serotype 2 is found commoaily in 2–22 week old pigs, S. suis type 2 is a zoonosis. It can cause meningitis and septicaemia in man (Christensen & Kronvall 1985). Several other serotypes of S. suis have also been identified on the basis of the capsular poly-saccharide (Perch et al. 1983, Hommez et al. 1986). We present a case where we isolated S. suis types 1 and 2 from the brain and lungs respectively of the same diseased suckling piglet. This i/s the first reported case of S. suis types 1 and 2 in Finland.  相似文献   

18.
Neospora caninum is a newly described coccidian parasite which has been found in various species such as the dog, cattle, horse, sheep and goat. Morphologically it resembles Toxoplasma gondii with which it is related (Holmdahl et al. 1994), and with which it has earlier been confused. The life cycle of N caninum is only partially known. Tachyzoites and tissue cysts are the only known stages of the parasite, and transplacental transmission is the only known route of infection. Subclini-cally infected dams can transmit the parasite to their fetuses and successive offspring from the same mother might be born infected (Dubey et al. 1990b). Clinical neosporosis is mostly seen in pups or young dogs, and the majority or all pups in a litter are often affected. The disease is characterized by ascending paralysis of the legs, with the hind legs more severely affected than the front legs, paralysis of the jaw, difficulty in swallowing and muscle flaccidity and atrophy (Dubey 1992, Dubey & Lindsay 1993). Fatal infections with N caninum in dogs have been reported from many countries, e.g. Norway (Bjerkäs & Presthus 1988), USA (Dubey et al. 1988), Sweden (Uggla et al. 1989a,b) and the United Kingdom (Dubey et al. 1990a). Serological surveys for antibodies to N. caninum in dogs from Kansas, USA and England have shown a prevalence of 2 and 13%, respectively (Lindsay et al. 1990, Trees et al. 1993).  相似文献   

19.
Among other factors the nutrient utilization of a cow is influenced by its individual physiological and genetic predisposition. There are large differences within cows in the manner of partition of the nutrients that may affect the size and activity of the individual organs and the whole body composition. High genetic merit dairy cows have a higher potential rate of protein excretion than medium genetic merit dairy cows even when energy and protein intake are equal. Medium genetic merit dairy cows show higher potential rates of protein and fat deposition of the body. This phenomenon was partly explained by the regulatory functions of the hormone insulin (see Brockman and Laarveld 1986; Broucek et al. 1991; Wylie et al. 1998). Additionally, it is widely considered that the somatotropic axis [growth hormone, growth hormone releasing factor and insulin-like growth factor I (IGF-I)], could be involved, as one of the key control and balance mechanisms which regulate the partition of nutrients (Breier and Sauerwein 1995; Schams 1995; Knight 1997). Several studies have provided insights into the physiological action of these and further hormones, transport proteins and enzymes, e.g. the erythrocyte-type glucose transporter, the insulin-responsive glucose transporter or the glycerol-3-phosphate dehydrogenase, and indicate that these molecules may affect nutrient repartitioning and utilization as well as milk yield, growth and fat accumulation (Mathews et al. 1988; Bauman and Vernon 1993; Burton et al. 1994; Girard et al. 1994; Binelli et al. 1995; Zhao et al. 1996; Abe et al. 1997). However, the mechanisms of regulation of most of these processes are insufficiently known. This paper presents a comparison of mRNA patterns of tissues potentially associated with protein and energy turnover in lactating cows of different metabolic types. The technique of differential display of messenger RNA species originally described by Liang and Pardee (1992), has already been applied as a powerful tool for cloning genes that are differentially expressed in various tissues or under altered conditions in the same tissue (e.g. Liang et al. 1993; Aiello et al. 1994; Li et al. 1994; Nishio et al. 1994). This method was applied to characterize the expression patterns in 12 tissues of three cows with divergent metabolic types (milk type, meat/milk type, and meat type) by the display of differentially and identically expressed cDNA bands. The aims of this exploratory study were first to indicate which of the 12 tissues analysed are mainly involved in trait differentiation according to their differentially displayed mRNA patterns. Secondly, the results of this study represent the prerequisite for the identification of tissue-specific expressed sequence tags in general, and individual or type-dependent differentially expressed sequence tags in particular.  相似文献   

20.
Hungary has a long-standing tradition in Merino breeding and improvement. During the past decades several attempts have been made to introduce a number of other sheep breeds. Although this effort was not in vain the majority of the sheep population is still the Hungarian Merino breed. The adaptability, endurance and excellent wool-producing ability of this breed is first rate and is worth preserving (V eress et al. 1997). The profitability of a sheep production system is determined by both fertility and production traits. Reproduction performance is usually defined as litter weight per dam per year. Progress can be achieved through various ways. One of them is frequent lambing which also has the advantage that lamb production becomes more consistent throughout the year. Another possibility is producing larger litter sizes (LS), and yet a another opportunity for increased production is having lambs with larger weights (WT). Simultaneous enhancement can also be achieved if there is no antagonism between these traits. From these several fertility traits LS from the first to the fifth parity was chosen for analysis as LS is one of the most important traits concerning reproduction performance. Of the production traits, WT measured at various ages, greasy fleece weight (GFW) from the first five shearings, staple length (SL) and fibre diameter (FD) at the age of 1 year were taken into the analysis. According to other studies there are several factors influencing the above mentioned traits, namely age, season of previous lambing (PLS), type of birth (TOB), and sex. In general, LS increased with advancing age (L ong et al. 1989; B unge et al. 1990; A p D ewi et al. 1996). For GFW the peak of production was achieved in a relatively early age of 3 years, reported by V eress (1969) and by T urner and Y oung (1969). The effect of PLS on LS was that smaller litters were observed with previous lambing seasons of summer and autumn (L ong et al. 1989). TOB and sex effect on WT have been investigated by several authors (T urner and Y oung 1969, p. 46, 51.; S hrestha and H eaney 1985; M avrogenis 1988; B unge et al. 1990; J urado et al. 1994; V eress et al. 1995; S hrestha et al. 1996). Single-born lambs are heavier than multiples although this difference decreases with age. All authors also agree that male lambs are heavier than females. TOB and sex effect on GFW were reported by T urner and Y oung (1969). T urner and Y oung labelled the TOB effect as a ‘maternal handicap’ as the effect is noticeable even in maturity but decreasing by age. T urner and Y oung (1969) also observed that the WT and GFW of male animals exceeds that of the females, but, unlike with the previous effect, the difference increases with age. There was a negligible difference between sexes in SL and FD. Studying the results of numerous authors, estimates of the genetic parameters of LS, WT, GFW, SL, and FD were found to be generally consistent. Heritabilities of LS ranged from 0.05 to 0.08 (A l -S horepy and N otter 1996; A p D ewi et al. 1996; for litter size at first parity only). A p D ewi et al. (1996) found very high (>0.9) genetic correlations between the first and adult litter size. Heritabilities estimated for WT were higher than those of the fertility traits and ranged in the interval of 0.05–0.47 (S hrestha and H eaney 1985; L ong et al. 1989; B unge et al. 1990; K umar and R eheja 1993; J urado et al. 1994; A l -S horepy and N otter 1996). Genetic correlations between yearling and adult WT were high (J urado et al. 1994; 0.85; A l -S horepy and N otter 1996; 0.85–1.0). GFW heritabilities reported by B lair et al. (1985); T urner and Y oung (1969) were about 0.2 thus also exceeding those of the fertility traits. Regarding the genetic parameters of SL & FD, N otter and H ough (1997); M orris et al. (1996) reported that the heritability of SL and FD was higher than that of GFW (026–0.34; 0.47–0.58). Genetic correlations among production traits were mainly low (M orris et al. 1996; and T urner and Y oung 1969). The objectives of this paper were to determine whether the characteristics of the Hungarian Merino sheep population correspond with the features given in the literature review. Thus the objectives were to obtain the factors influencing the traits examined and to estimate genetic parameters of LS, WT, GFW, SL, and FD, respectively.  相似文献   

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