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"Superantigens" may shed light on immune puzzle   总被引:2,自引:0,他引:2  
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I have analyzed the available amino acid sequence data from 30 myelomatosis-derived proteins. Several types of variation are apparent. I conclude that a major and genetically predetermined contribution to the variability of these proteins and of antibodies could be provided by chromosomal rearrangements resulting from somatic recombination between similar but not identical genes in antibody gene pairs. My hypothesis suggests many new types of experiment and can be tested (31).  相似文献   

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Cannatella DC 《Science (New York, N.Y.)》2008,320(5878):874; author reply 874
Becker et al. (Reports, 14 December 2007, p. 1775) reported that forest amphibians with terrestrial development are less susceptible to the effects of habitat degradation than those with aquatic larvae. However, analysis with more appropriate statistical methods suggests there is no evidence for a difference between aquatic-reproducing and terrestrial-reproducing species.  相似文献   

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