Die testikuläre Feminisierung beim Rind als Sterilitätsursache von Färsen

As a contribution to knowledge of anoestrus in heifers, a case of testicular feminisation in a Friesian heifer is reported. This is the first case of this unusual intersex form in German breeds of cattle. 2. The genital syndrome “testicular feminisation” originates in genotypically male animals with foetal testicular insufficiency resulting in diminished or absent androgen production. For this reason, despite the male karyotype, phenotypically female individuals develop with normal female external genitalia, but lacking a uterus and having a short vagina. The male internal organs are also absent, apart from the large intra-abdominal testes. 3. Testicular parenchyma and tubular epithelium are arrested in a state of embryonic development, with severe degeneration of the tubular epithelium which do not contain cells at more developed stages of spermiogenesis. 4. Testicular feminisation is genetically conditioned and is due to a recessive, sex-linked gene which is transmitted by female animals. The frequency of occurrence of this gene and the incidence of the defect in the population appear to be very low.