Nonhuman primate dermatology.

Clinical skin disease in the NHP is common and generally similar in appearance, clinical approach, and therapy to that seen in other animals and humans. Because most skin diseases of NHP are potentially zoonotic, care must be taken when handling the animals. Traumatic injury to the skin with secondary bacterial infection is the most common condition seen clinically. Virus-induced skin disease is probably the next most commonly seen, followed by mycotic infections, parasitisms, cancer, and miscellaneous rare conditions.     

Nonhuman primate dentistry.

Dental procedures in nonhuman exotic primates present many out of the ordinary problems that are related to variations of the teeth and oral cavity and serious zoonotic considerations and procedural time limitations. Most of these challenges can be met with appropriate knowledge, training, equipment, and rapidity and precision in performance. Unfortunately, alacrity generally comes from repetitive performance of procedures and entails a learning curve.     

Primate anesthesia.

This article provides an update on some of the recent advances in primate anesthesia. It focuses in particular on some of the newest information available regarding the effects of opioids and alpha-2 agonists in primates, and how these effects are different from what we might expect in other companion animals. It reviews the important properties of the latest induction and inhalation agents, and stresses the need for continuous monitoring of the anesthetized patient.     

Nonhuman primates and the practitioner

This article presents a practical introduction to nonhuman primate medicine for the private practitioner. The general approach to handling these animals for examination as well as methods of restraint are described. Preventive medicine and husbandry programs are discussed and common disease problems are outlined.     

Nonhuman primate dermatology: a literature review

In general, veterinary dermatologists do not have extensive clinical experience of nonhuman primate (NHP) dermatoses. The bulk of the published literature does not provide an organized evidence-based approach to the NHP dermatologic case. The veterinary dermatologist is left to extract information from both human and veterinary dermatology, an approach that can be problematic as it forces the clinician to make diagnostic and therapeutic decisions based on two very disparate bodies of literature. A more cohesive approach to NHP dermatology – without relying on assumptions that NHP pathology most commonly behaves similarly to other veterinary and human disease – is required. This review of the dermatology of NHP species includes discussions of primary dermatoses, as well as diseases where dermatologic signs represent a significant secondary component, provides a first step towards encouraging the veterinary community to study and report the dermatologic diseases of nonhuman primates.     

非人灵长类动物慢性肾病模型研究进展

慢性肾病(Chronic kindey disease,CKD)作为高发病率、低防治率的常见疾病之一,目前尚无非人灵长类动物在CKD模型中应用的进展报告。建立CKD模型的非人灵长类动物主要是猕猴属中恒河猴、食蟹猴和豚尾猴3种。从造模方式看,主要采用的方法有诱导性模型和自发性模型两种。诱导型造模可分为药物诱导、免疫诱导、重金属化合物诱导、辐射损伤、生物诱导等不同方法。从肾脏病理改变看,有以肾小球病理改变为主,如猪尾猴疟原虫、牛丙种球蛋白等诱导者;有以肾小管病理改变为主,如氯化镉、顺铂等诱导者;有兼顾肾小球和肾小管损伤,如猴免疫缺陷病毒(SHIV)诱导者。为利用非人灵长类动物进行CKD相关研究提供了方法学汇总,具有一定参考价值。