犬瘟热的综合疗法与体会

犬瘟热是由副粘病毒科的犬瘟热病毒所引起的一种犬科动物的烈性传染病。其特点是传播速度快,流行范围广,死亡率高。另     

Anosmia associated with canine distemper

The sense of smell in dogs infected with canine distemper virus (CDV) was examined by use of EEG olfactometry, behavioral olfactometry, and electro-olfactography. Infection with CDV was confirmed by a direct immunofluorescence technique in 8 active cases and was suggested by clinical history compatible with canine distemper 10 to 26 weeks earlier in 6 cases. Pathologic alterations of the olfactory mucosa in 3 clinically affected dogs was examined by light microscopy. Infection with CDV was found to be associated with anosmia and lack of recorded responses on electro-olfactogram in 8 of 8 dogs with clinical signs of acute distemper from naturally acquired infections. Anosmia was found in 5 of 6 dogs that had recovered from acute distemper 10 to 26 weeks earlier. The sixth dog had hyposmia, with abnormalities on the electro-olfactogram. Histologic examination was not performed on the 6 dogs that had recovered. Histologic lesions observed at necropsy in 3 dogs that had had clinical signs of acute distemper were those of subacute purulent rhinitis and atrophy of the olfactory epithelium. Altered olfactory function could be explained by mucopurulent exudate blocking odors from olfactory receptors in the acutely affected dogs, but alteration of olfactory function in the dogs that had recovered without clinical evidence of rhinitis could not be explained.     

犬瘟热预后状况之我见

本文结合临床经验，对肠炎型、肺炎发热型及神经型的犬瘟热的临床症状及预后做了全面的介绍，并指出了与其他易混淆疾病的鉴别诊断的方法，特别是对神经型犬瘟热的诊断，有相当一部分用试剂盒采进行确诊时显示为阴性。     

Lead poisoning and canine distemper

Clinical signs of lead poisoning are rather nonspecific and have often been confused with those of canine distemper. Described is a case of canine distemper which on clinical examination, haematology and biochemical test (U-ALA) indicated intoxication with lead. The case demonstrates the value of taking blood samples for the purpose of estimation of lead level in suspect cases of lead poisoning.     

犬瘟热的治疗

犬瘟热是犬瘟热病毒引起的犬科、鼬科和浣熊科动物的一种急性、热性传染病。临床上以呈现双相热型、鼻炎、严重的消化道障碍以及呼吸道炎症等为特征。本病常呈地方性流行,成为犬的主要传染病之一。且以幼犬发病较多。笔者自从1995年从事动物诊疗工作以来,治疗犬瘟热34例,治愈31例,治愈率94％,现简介如下。     

犬瘟热的治疗与预防

犬瘟热是由犬瘟热病毒(CDV)引起的急性高度接触性、传染性、致死性传染病.犬瘟热一般分为4个类型:呼吸道型(肺炎型)、消化道型(胃肠炎型)、神经型和混合型.     

犬瘟热的临床鉴别诊疗要点

犬瘟热早期感染症状易与其他病因所致疾病混淆,在临床上往往因不能及时诊断、贻误治疗时机而给宠物业带来巨大的经济损失。在临床上,早诊断、早治疗是治愈犬瘟热的根本。笔者就临床上如何对犬瘟热进行鉴别诊疗谈一点体会。     

狼犬瘟热的诊治

犬瘟热（CD）是由副黏病毒科麻疹病毒属的犬瘟热病毒引起的犬和肉食目许多动物的一种高度接触性传染病。临床上以眼、鼻流浆液性分泌物,体温呈双相热。病情恶化后,眼睑肿胀,呕吐、下痢、精神萎靡以及消化道和呼吸道卡他性炎症、神经症状等为主要特征。有关野生动物患犬瘟热的报道较少,根据笔者在某公园实习期间所见的两起狼犬瘟热病例,现报告如下。     

国内流行犬瘟热病毒DNA重组疫苗的初步研究

为了探究H蛋白的免疫原性以及抗体效价,构建了1株犬瘟热病毒(CDV)ZH-10株H基因的真核表达载体pCI-H,对表达产物的免疫原性进行了初步研究,并进行了小鼠的DNA免疫试验。结果显示,pCI-H免疫组血清可与感染病毒的MDCK细胞发生特异性IPMA反应呈现特异的棕红色;ELISA血清抗体滴度可达1:28~1:79;病毒中和抗体可达1:11~1:32。研究结果表明,H蛋白具有免疫原性,但诱导抗体效价不足,需进一步完善。