Surgical Treatment of Gastroduodenal Obstructions in Foals

Thirteen foals that ranged in age from 4 days to 4 months were presented for treatment of gastroduodenal obstruction. The site of obstruction was determined from examination of standing right lateral contrast radiographs of the caudal part of the thorax and abdomen. Depending on the site, the obstruction was bypassed by esophagogastrostomy, gastroduodenostomy, partial gastrectomy with gastroduodenostomy, duodenojejunostomy, or gastrojejunostomy followed by jejunojejunostomy. Six of the 13 foals (46%) survived. All foals with pyloric stenosis survived. Seven of eight foals with duodenal stenosis died. Deaths were due to complications unrelated to the primary gastroduodenal obstruction.     

牛肠阻塞的手术治疗

肠阻塞又称肠便秘、便秘疝,是家畜因肠机能紊乱,粪便积滞不能运转,而使肠腔发生完全或部分阻塞的一种急性腹痛症.本病主要发生在马骡,牛羊较少见.但在我省肠阻塞也是黄牛的常见病之一,一般情况多与日常饲养管理、使役及气候等因素有关.根据相关资料显示,肠便秘在家畜胃肠腹痛症中约占50%～60%,其中以小结肠阻塞、胃状膨大部阻塞、骨盆曲阻塞多见.笔者采用手术治疗,效果明显,现介绍如下供参考.     

Surgical Correction of Bilateral Ectopic Ureters in Two Foals

Case reports of ectopic ureters in a 2 1/2-month-old colt and a 4 1/2-month-old filly are presented. Diagnosis was made by retrograde cystography and excretory urography. The ureters were surgically transposed into the bladder. A functional urinary system was reestablished in both foals, but they died of postoperative complications.     

中西医结合治疗牛百叶干研究

为研究中西医结合治疗牛百叶干的方法及效果。以一例患有瓣胃阻塞的病牛为例,经过中医单独治疗无效后,联合进行西医手术治疗和跟踪回访,评估中西医结合治疗效果,以期为该病的治疗与预防提供参考。研究结果表明,牛百叶干病是常见的一种消化道感染疾病之一,该病种疾病早期临床症状一般不甚明显,因此易被许多牛养殖户所忽略,等到发现病牛临床症状明显后,因其疾病带来了很多损失。该病主要发病原因之一,是由于牛在使役后的时间供给过度、牛的运动时间不足,或长期饲喂一些大量含粗纤维多的干硬、酸性、变质的动物饲料,加之牛每天饮水量的不足,致使牛体内火盛,病牛体内一般不仅严重缺水,而且在原本滞留于牛胃小叶里的饲料难以正常运转下行。中西医相结合对牛百叶干进行治疗,发病及时进行抢救,可具有良好的预防治疗康复效果,避免养殖户因此遭到重大经济损失。     

Surgical Treatment of Sand Colic Results in 40 Horses

A retrospective study of 40 horses that underwent surgical treatment for sand colic was performed. Three horses were euthanatized and one died during surgery. Of the 36 horses that recovered from anesthesia, five died before discharge from the hospital and seven died after discharge. Twenty-four horses survived at least 12 months. Sand impaction of the right dorsal colon was present in 26 horses. In addition to sand impaction, 10 horses also had colonic displacement or volvulus.     

Right Ventricular Outflow Obstruction Caused by Primary Cardiac Neoplasia

Obstruction to pulmonary blood flow as a result of neoplasia in the right ventricular outflow tract is described in two dogs. Whereas one dog had exertional syncope and a systolic ejection murmur, the other had signs of congestive failure and hypoxia. In both animals the mass was detected in the right ventricle with two-dimensional echocardiography and confirmed angiographically. Although rare, primary right ventricular neoplasia represents a potentially treatable form of cardiac disease and should be considered as a cause of acquired outflow tract obstruction.     

Transendoscopic Laser Treatment of Guttural Pouch Tympanites in Eight Foals

Guttural pouch tympanites was diagnosed in eight foals with respiratory stridor and tympanic swelling in the parotid region. Three foals were treated by transendoscopic neodymium:yttrium aluminum garnet (Nd:YAG) laser fenestration of the median septum between the guttural pouches. One foal died of pneumonia, and the other two foals recovered completely, although the fenestration later closed in one foal. Five foals were treated by creating a salpingopharyngeal fistula using transendoscopic laser irradiation: complete resolution of the tympanites occurred. Transendoscopic laser surgery in standing foals may be a reasonable alternative to conventional surgery and general anesthesia for correction of guttural pouch tympanites.     

Idiopathic Hypocalcemia in Foals

Five thoroughbred foals (4 fillies and 1 colt), all in good to excellent body condition, ranging in age from 4 days to 5 weeks at the time of onset of signs, were presented to 2 Kentucky equine hospitals from 1992 through 1996. All 5 foals presented with tachycardia, hyperhidrosis, diarrhea or a recent history of diarrhea, and muscle rigidity or stiff gait. Four of the 5 foals presented for recumbency, seizure-like activity with opisthotonos, or pronounced extensor muscle rigidity. All 5 foals were hypocalcemic. All foals either died or had euthanasia performed. None responded to oral calcium supplementation. The cause of the hypocalcemia was unknown. Different idiopathic hypocalcemia syndromes may exist in foals.     

Mucosal mRNA Cytokines’ Profile of Gastric Wall in Neonatal Foals: Comparison with Endoscopy and Histology

Gastritis and gastric ulcerations occur frequently in neonatal foals. The relationship between cytokines expressed by gastric mucosa and gastric histopathology in healthy or sick foals has never been investigated. The aim of this study was to compare the histological diagnosis and endoscopic view with cytokine expression (TNF-α, IL-1β, IL-4, IL-8, IL-13, and IFN-γ) of gastric mucosa. Twenty-two foals were definitively enrolled in the study: 19 were critically ill, and 3 were healthy foals. Gastric biopsy specimens were collected for histological examination and for cytokine mRNA qualitative real-time PCR analysis. This study shows that there is a substantial agreement between histology and endoscopy and that foals with evidence of gastritis and gastric ulcerations have higher probability of expressing TNF-α. Moreover, the overall profile of cytokines expression, with a low percentage of IFN-γ, a high percentage of IL-4, and the absence of IL-13, suggests a down-regulation of the Th1 cell-mediated immune response and an impaired Th2 response in the gastric wall in the neonatal period.     

The Diagnosis and Surgical Correction of Congenital Portosystemic Vascular Anomalies in Two Calves and Two Foals

Two calves and two foals presented with episodic clinical signs of diffuse central nervous system disease. Portosystemic anomalies were tentatively diagnosed based on the history, clinical signs, and increased serum concentrations of blood ammonia and total serum bile acids with normal concentrations of liver derived enzymes. One calf died before intraoperative contrast portography, whereas the other calf and both foals had marked clinical improvement after intensive medical therapy. Surgical correction was attempted in these three animals and was successful in one foal. A right paracostal celiotomy was superior to a ventral median approach for exposure to the portal vascular system and shunt access.     

Acute Effects of Ivabradine on Dynamic Obstruction of the Left Ventricular Outflow Tract in Cats with Preclinical Hypertrophic Cardiomyopathy

Background

Ivabradine is a negative chronotropic drug with minimal effects on central hemodynamics. Its effect on dynamic obstruction of the left ventricular outflow tract (LVOT) in cats with hypertrophic cardiomyopathy (HCM) remains unknown.

Hypothesis/Objectives

Ivabradine reduces dynamic obstruction of the LVOT in cats with HCM.

Animals

Twenty‐eight client‐owned cats with preclinical HCM and dynamic LVOT obstruction.

Methods

Randomized, double‐blind, active‐control single dose study. Cats received a single dose of either ivabradine (0.3 mg/kg PO) or atenolol (2 mg/kg PO). Heart rate, echocardiographic variables, and systolic blood pressure (SBP) were recorded before and 3 hours after drug administration. Statistical comparisons were made using ANCOVA.

Results

Peak velocity in the LVOT was significantly decreased compared to baseline for both drugs; however, the effect was more prominent with atenolol (mean reduction 2.53 m/s; 95% CI 2.07–3.13 m/s) compared to ivabradine (mean reduction 0.32 m/s; 95% CI −0.04 to 0.71 m/s; P < .0001). Echocardiographic indices of systolic function were largely unchanged by ivabradine, but significantly reduced by atenolol.

Conclusions and Clinical Importance

A single dose of ivabradine decreases dynamic LVOT obstruction in cats with HCM, but the clinical effect is negligible and inferior compared to that achieved by atenolol.     

牛食道阻塞防治

牛食道阻塞又被称为食道梗塞,是因为食道中被大块食物堵塞,难以下咽所引发的一种急性食道疾病。按照阻塞程度的不同划分为完全阻塞和不完全阻塞2种。按照阻塞部位的不同可以划分为颈部食道阻塞、胸部食道阻塞和腹部食道阻塞3种。因阻塞性质和阻塞程度不同,会继发不同程度的瘤胃臌气。牛食道阻塞具有发病急、发病突然、发病过程快、致死率高的特点,发生后如果不能立即采取措施抢救,患病牛在短时间内会死亡。为提高食道阻塞救治成功率,该文主要探讨牛食道阻塞的诊断和防治过程。