山羊传染性胸膜肺炎研究进展

山羊传染性胸膜肺炎是由山羊支原体山羊肺炎亚种引起的一种山羊常见的高度接触性呼吸道传染病,有传染快速,发病率、死亡率高的特点,给山羊养殖业带来巨大损失。本文从病原学、流行病学、临床症状以及诊断与防控方面对山羊传染性胸膜肺炎进行综述,帮助读者更加全面、深入的了解本病,以期为山羊传染性胸膜肺炎的诊断和防治提供新思路。     

山羊传染性胸膜肺炎继发流产病例的诊断

为对贵州省某规模养羊场临床表现咳嗽、消瘦及流产症状病死山羊进行病因确定性诊断,采用分子生物学方法对病死山羊进行山羊传染性胸膜肺炎(CCPP)病原与山羊流产衣原体核酸检测。结果表明,从病死母羊肺组织中检测到绵羊肺炎支原体(Mo)核酸,未检测到丝状支原体山羊亚种(Mmc)核酸,病死母羊子宫组织中山羊流产衣原体检测均为阴性,病例确诊为CCPP。序列分析显示Mo感染可能与流产症状有关。研究结果将为贵州省预控此类疫病流行暴发提供技术支持。     

传染性胸膜肺炎的防制

胸膜肺炎放线杆菌是猪胸膜肺炎的病原因子。猪传染性胸膜肺炎是一种严重的致死性疾病,可危害所有年龄的猪。据认为,工业化养猪促使该病发生率增高的因素。     

Contagious caprine pleuropneumonia: Some observations in a field vaccination trial using inactivatedMycoplasma strain F38

The efficacy of an inactivated Mycoplasma strain F38-saponin vaccine in natural infection with contagious caprine pleuropneumonia was investigated. A total of 10,000 goats were vaccinated, out of which 400 were regularly monitored for a period of six months post-vaccination. Immunised animals remained free from infection throughout the period of observation. The antibody response was followed using complement fixation and slide agglutination tests. Both tests could detect F38 antibody in the majority of vaccinated goats but the slide agglutination test was found to be more sensitive than complement fixation. The significance of the results is discussed.     

Comparative evaluation of different therapeutic protocols for contagious caprine pleuropneumonia in Himalayan Pashmina goats

Tropical Animal Health and Production - Therapeutic management of contagious caprine pleuroneumonia (CCPP) involves mostly the use of oxytetracycline followed by enrofloxacin and rarely tylosin. In...     

Contagious bovine pleuropneumonia a review

Summary

The prevalence, characteristics of the aetiological agent, clinical signs, pathological changes, pathogenesis, epizootiology, microbiological and serological diagnosis, prevention, and control of contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides subspecies mycoides SC type, are reviewed New aspects of the disease are discussed A renewed interest in this disease is important because of outbreaks in Southern Europe since 1980. When, at the end of 1992, the national borders of the countries of the European Community are abolished, it is conceivable that the disease will be introduced by cattle imported into CBPP‐free countries.     

Treatment of contagious caprine pleuropneumonia

Goats that had been inoculated with the causal organism of contagious, caprine pleuropneumonia and treated, within a few days, with oxytetracycline or tylosin, were less severely affected than infected, untreated control goats. However, 20% of treated cases remained infective and were, presumably, capable of transmitting the infection.     

Contagious caprine pleuropneumonia outbreak in captive wild ungulates at Al Wabra Wildlife Preservation, State of Qatar.

Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae is a highly contagious and serious respiratory disease of domestic goats, characterized by coughing, severe respiratory distress, and high mortality rates. The lesions at necropsy are mainly a fibrinous pleuropneumonia with increased straw-colored pleural fluid. An outbreak of CCPP in wild goat (Capra aegagrus), Nubian ibex (Capra ibex nubiana), Laristan mouflon (Ovis orientalis laristanica), and gerenuk (Litocranius walleri) occurred at Al Wabra Wildlife Preservation in the State of Qatar. The disease was suspected because of the clinical symptoms and the necropsy findings and was confirmed by the isolation and identification of the causative organism. This new finding indicates that CCPP should be considered a potential threat to wildlife and the conservation of endangered ruminant species, especially in the Middle East, where it is enzootic because of its presence in chronic carriers. Susceptible imported animals should be quarantined and vaccinated. The preferred samples for diagnosis are the pleural fluid, which contains high numbers of Mycoplasma, and sections of hepatized lung, preferably at the interface of normal and diseased tissues. Samples must be shipped to diagnostic laboratories rapidly, and appropriate cool conditions must be maintained during shipping.     

Effect of danofloxacin (Advocin A180) on goats affected with contagious caprine pleuropneumonia

The efficacy of danofloxacin (Advocin A180) was evaluated for the treatment of contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae. Ten healthy Angora goats, confirmed free of CCPP, were exposed to clinically affected animals from a natural outbreak in Thrace, Turkey. After 14 days exposure, 8 goats showed pyrexia ( > or = 41 degrees C). Shortly after, the Angora goats were divided randomly into two groups. Five of these were injected with danofloxacin (6 mg/kg subcutaneously), which was repeated after 48 h; the five remaining animals received saline. Goats were monitored clinically and blood samples were collected for serology. Animals with severe disease were withdrawn from the trial. Goats completing the study were euthanized at day 42. Lung tissue and bronchial fluid were collected for mycoplasma isolation. All danofloxacin-treated goats showed resolution of clinical disease by the end of the trial. Two saline-treated goats failed to complete the study owing to CCPP. Danofloxacin-treated goats showed fewer lung lesions and had significantly lower combined clinical scores than saline controls (p < 0.001). Danofloxacin was found to be highly effective in the treatment of CCPP in goats.     

Contagious bovine pleuropneumonia. A review.

The prevalence, characteristics of the aetiological agent, clinical signs, pathological changes, pathogenesis, epizootiology, microbiological and serological diagnosis, prevention, and control of contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides subspecies mycoides SC.type, are reviewed. New aspects of the disease are discussed. A renewed interest in this disease is important because of outbreaks in Southern Europe since 1980. When, at the end of 1992, the national borders of the countries of the European Community are abolished, it is conceivable that the disease will be introduced by cattle imported into CBPP-free countries.