Do magnetic fields influence soft tissue wound healing?--A preliminary communication

Magnetic fields have been considered for treating many ailments over man's history. There have been many anecdotal unsupported claims for successful treatment of soft tissue injury although reports have been more substantive in the orthopaedic field. The widespread clinical and veterinary use of a light self-adhesive magnetic foil in Europe prompted this trial of experimental wound healing. One hundred and sixty Sprague-Dawley rats had a linear 2.5 cm incision or a circular 1 cm skin defect made over the mid-dorsal spine. Equal numbers were randomised to receive either a magnetic foil or a dummy (control) dressing. At three, seven, 10 or 14 days linear wounds were distracted using a tensiometer; open defects were measured, excised and assayed for collagen content; 14-day wounds were examined histologically. Although wound tensile strengths increased and open wounds decreased in size with increase of hydroxyproline, there were no statistically significant differences between treated or control animals. Although easy to apply the alternate magnetic foil (giving 400 Gauss at 7 mm) conferred no statistically significant effect on soft tissue healing.     

Bone healing

Bone is a tissue composed of organic (cells and matrix) and inorganic (mineral) components. When the mechanical strength of bone is exceeded, fracture occurs. Healing progresses through inflammatory, reparative, and remodeling phases similar to other tissues, but, unlike other tissues, bone possesses the unique capability to completely regenerate and return to pre-injury strength. The bone healing process is influenced by many factors, including mechanical stress, biochemical mediators, bioelectric and piezoelectric properties, and neural and endocrine influences. In short, any factor capable of altering the metabolism of osteogenic cells can influence bone healing.     

Second-intention healing

Second-intention healing (contraction and epithelization) is most appropriate for heavily traumatized, contaminated wounds that may have a prolonged debridement phase. Therapy during healing can promote rapid debridement and faster healing. Healing of lower limb wounds by second intention may be protracted, owing to poorer wound contraction and excessive granulation tissue production as compared with body wounds.     

Intestinal healing and methods of anastomosis

Optimal intestinal healing occurs when like layers of the intestinal wall are aligned. Hand-sewn, double-layer, end-to-end anastomosis that apposes the mucosa and produces slight inversion of the seromuscular layer is recommended to minimize adhesion formation and provide reasonable alignment of the intestinal layers. Stapled, everted, triangulated, end-to-end anastomosis is not recommended because of extensive adhesion formation and poor healing of the intestinal layers. The preferred stapled techniques create an inverting, side-to-side stoma between the bowel segments.     

Effects of ketanserin on hypergranulation tissue formation, infection, and healing of equine lower limb wounds

The objective of this multicentre, randomized, controlled field study was to determine the efficacy of ketanserin gel in preventing exuberant granulation tissue formation (hypergranulation) and infection in equine lower limb wounds. Horses and ponies (n = 481) with naturally occurring wounds were randomized to either topical treatment with ketanserin gel (n = 242) or a positive control (Belgium, Germany: ethacridin lactate solution, n = 120; France, United Kingdom: malic, benzoic, and salicylic acid [MBS] cream, n = 119). Treatment continued until the wound healed (success), formed hypergranulation tissue (failure), or became infected (failure). Treatment was terminated after 6 months in all remaining animals. Ketanserin was successful in 88% of cases. Wounds treated with ketanserin were 2 and 5 times more likely to heal successfully than were those treated with MBS or ethacridin lactate, respectively. Ketanserin gel is thus more effective than these standard treatments in preventing hypergranulation tissue and infection of equine lower limb wounds.     

Wound management in teleost fish: biology of the healing process, evaluation, and treatment.

Wound healing, although similar to terrestrial vertebrates, occurs faster in fish species in a proper aquatic environment. Wound management must involve identification and correction of potential noninfectious and/or infectious causes of disease. Wound evaluation includes assessment of the wound as well as systematic examination of the patient, water quality conditions, and husbandry practices. Diagnostic evaluation should, at a minimum, include physical examination, skin/cornea (if indicated) scraping, and lesions cultures. The clinician should also consider full thickness wound biopsies, gill and fin biopsies, blood collection, and radiographs for systemic evaluation as well. Local wound management should follow basic principles of wound care including cleaning and lavage, debridement, primary closure if indicated, and local and/or systemic antiinfectives. Monofilament absorbable or nonabsorbable sutures are commonly used for primary closure of wounds. Diagnostic results, patient and client compliance, and economic impact should guide systemic methods of treatment for wound care. Options for systemic therapy include oral or gavage, parenteral, bath, or prolonged immersion treatments. With bath or prolonged immersion therapies, aquatic systems must be properly prepared for treatment. Treatment of identified pathogens, proper water quality and husbandry, supportive care and nutrition must all be provided to promote an ideal wound healing environment for the teleost fish.     

Literary Probe of O. Henry's Short Stories

O.Henry’s short stories are popular all over the world.His stories are diversified in subjects,and the artistic features of his works are prominent as well.     

试论《搜神记》中体现的儒家思想

《搜神记》是东晋思想家、史学家干宝的心血之作。他以史官的身份记录鬼神故事,在汉儒的天人感应思想影响下,于神秘莫测的鬼神世界的描绘中自始至终贯穿着儒家“孝”、“德”、“仁”、“礼”等伦理观念。     

警犬学校带犬女生二三事

带犬女民警接受警犬技术专业本科学历教育，在中国乃至世界都是首创。中国刑警学院警犬技术系（公安部警犬技术学校）首批招收了29名带犬女生。