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1.
Experiments were carried out to examine the effects of a Fusarium contaminated wheat (10 mg deoxynivalenol and 0.76 mg zearalenone, ZON, per kg dry matter) and of a detoxifying agent (Mycofix Plus, Biomin GmbH, Herzogenburg, Austria) on the growing performance of bulls, carry-over of ZON and its metabolites into body fluids and tissues, and on nutrient digestibility in wethers. The experiments were designed according to a complete two by two factorial approach which meant that both the uncontaminated control wheat and the Fusarium toxin contaminated wheat were tested both in the absence and presence of Mycofix Plus. The growing experiment with bulls (n = 14 per treatment) covered the live weight range between 244 kg and 460 kg. The respective wheat batches were included in the concentrate portion at 65%. Concentrates were fed according to plan whereas maize silage was offered for ad libitum consumption. Daily dry matter intake and live weight gain [kg per animal and day] were 7.40, 7.52, 7.51 and 7.49 and 1.367, 1.296, 1.380 and 1.307 for bulls fed the unsupplemented control wheat, the supplemented control wheat, the unsupplemented and Fusarium toxin contaminated wheat and the supplemented Fusarium toxin contaminated wheat, respectively. ZON and its metabolites were not detected in edible tissues. The most striking effects of feeding the Fusarium toxin contaminated wheat on carcass characteristics were a reduced dressing percentage, an increased weight of the emptied gastro-intestinal tract and a reduced weight of the testicles. No effect of the detoxifying agent was seen for these parameters whereas heart weight increased independently of Fusarium toxin contamination of the concentrates. Nutrient digestibility of the two wheat batches, unsupplemented or supplemented with Mycofix Plus was evaluated according to the difference method using wethers. Presence of Fusarium toxins in wheat did not influence its feeding value. The effects of the addition of the detoxifying agent were mycotoxin unspecific and resulted in an increase in apparent digestibility of crude protein and a decrease in crude fiber digestibility. It is concluded that feeding of Fusarium toxin contaminated wheat did not adversely affect performance of growing bulls (approximately 2.2 mg DON and 0.1 mg ZON per kg complete ration at a reference dry matter content of 88%) or nutrient digestibility in wethers. The effects of the detoxifying agent Mycofix Plus on growing performance and on nutrient digestibility were rather Fusarium toxin unspecific. The slightly negative effects on growing performance needs to be examined further.  相似文献   

2.
The aims of this study were to examine the effects of and possible interactions between dry matter (DM) intake and feeding Fusarium toxin-contaminated wheat on ruminal fermentation, serum chemical parameters and milk yield of dairy cows. Fourteen dairy cows equipped with ruminal and duodenal cannulas were analysed. All animals were fed the same ration, the daily feed amounts being adjusted to current performance. On DM basis, the ration consisted of 60% concentrate including 55% wheat [Fusarium-contaminated wheat (mycotoxin period) or control wheat (control period)] and was completed with 40% maize and grass silage. Each cow was fed the contaminated wheat [deoxynivalenol (DON), 8.21 mg/kg DM and zearalenone (ZON), 0.09 mg/kg DM] and the control wheat (0.25 mg DON/kg DM and 51 microg ZON/kg DM). As expected, a higher organic matter (OM) intake decreased the amounts of fermented crude nutrients related to the respective intakes. An increased amount of crude protein degraded (p < 0.05) and a lower molar percentage of propionate in the rumen fluid were observed when feeding the Fusarium toxin-contaminated wheat at increased OM intakes in comparison with the control wheat. The activities of serum aspartate aminotransferase (ASAT; p < 0.001), glutamate dehydrogenase (GLDH; p < 0.01) and gamma glutamyl transferase (gamma-GT; p < 0.01) increased with increasing OM intake and were not related to the mycotoxin contamination of the wheat.  相似文献   

3.
1. Diets with increasing proportions of Fusarium toxin-contaminated wheat (0, 170, 340 and 510 g CW/kg) were fed to male turkeys (BUT Big 6) from d 21 to d 56 of age. Each diet was tested with or without a non-starch-polysaccharide (NSP) hydrolysing enzyme preparation. Dietary deoxynivalenol (DON) and zearalenone (ZON) concentrations were successively increased up to approximately 5.4 and 0.04 mg/kg, respectively. 2. Weight gain decreased slightly with increasing proportions of CW, by 1.6, 0.7 and 3.6%, whereas other performance parameters remained unaffected. NSP enzyme supplements to the diets had no influence. 3. The weight of the emptied jejunum plus ileum, relative to live weight, decreased in a dose-related fashion whereby the NSP enzyme exerted an additional weight-decreasing effect. A similar weight-decreasing NSP enzyme effect was noted for heart weights. Activity of glutamate dehydrogenase in serum was significantly increased in groups fed the diets with the highest CW proportion, whereas gamma-glutamyl-transferase remained unaltered. 4. Viscosity in the small intestine was significantly reduced by supplementing the diets with the NSP enzyme. This effect successively decreased with increasing proportions of the CW. 5. Concentrations of DON and of its de-epoxidised metabolite de-epoxy-DON in plasma, liver and breast meat were lower than the detection limits of 2 ng/ml (plasma) and 4 ng/g, respectively, of the applied HPLC method. DON concentration in bile reached up to 13 to 23 ng/ml whereas de-epoxy-DON concentration was lower than 4 ng/ml. 6. ZON or its metabolites were not detectable in plasma, liver or breast meat (detection limits of the HPLC method were 1, 0.5 and 5 ng/g for ZON, alpha-zearalenol (ZOL) and beta-ZOL, respectively). Concentrations of ZON and alpha-ZOL in bile increased with dietary ZON concentration. The mean proportions of ZON, alpha-ZOL and beta-ZOL of the sum of all three metabolites were 19, 77 and 4%, respectively.  相似文献   

4.
The aim of the present study was to examine the effects of feeding Fusarium toxin-contaminated wheat to dairy cows on nutrient utilization in the rumen and on duodenal flow of deoxynivalenol (DON), zearalenone (ZON) and their metabolites. Six dairy cows fitted with a large rumen cannula and a simple T-shaped cannula at the proximal duodenum was used in two experiments. The experiments included a control period in which the uncontaminated control wheat was fed and a period in which the control wheat was replaced by the Fusarium toxin-contaminated wheat (8.05 and 7.15 mg DON/kg and 0.26 and 0.1 mg ZON/kg in Expts 1 and 2 respectively). The wheat portion of the daily ration amounted to 50% on a dry matter (DM) basis and rations were completed with hay or grass silage. Five of the six cows were non-lactating and the total daily DM-intake ranged between 4 and 12 kg. The pH-values and the concentration of volatile fatty acids in ruminal fluid were not significantly influenced by feeding the contaminated wheat. In contrast, the postprandial ammonia concentration was consistently higher when the mycotoxin-contaminated wheat was fed. Moreover, the flow of microbial protein and utilizable protein at the duodenum were reduced at the same time. The concentrations of DON and ZON and of their metabolites in freeze-dried duodenal digesta were either not detectable or negligible during the control periods whereas distinct concentrations were measured during the periods where the contaminated wheat was fed. DON was nearly completely metabolized to de-epoxy-DON and the flow at the duodenum ranged between 4% and 28% of DON-intake. The ZON metabolites alpha-zearalenol (ZOL) and beta-ZOL were recovered at the duodenum beside the parent toxin ZON. Their recovery as a percentage of ZON-intake ranged between 43% and 132%. In conclusion, feeding of Fusarium toxin-contaminated wheat altered the ruminal protein utilization. The question of whether this effect was a result of the mycotoxin being present in the rumen or of Fusarium growth-related structural (cell wall) changes of the wheat grain needs to be clarified. The low recovery of DON at the duodenum would indicate either a nearly complete degradation of the molecule in the rumen or an absorption by the mucosa of the rumen, whereas the higher ZON recovery would suggest a lower degradation of the parent toxin in the rumen and/or recovery of some bile-originating entero-hepatic cycling ZON/metabolites.  相似文献   

5.
Feeding experiments with diets containing Fusarium toxin-contaminated wheat were conducted to clarify the pathogenesis of immunological effects of Fusarium toxins to porcine spleen cells. Contaminated diets were fed to 36 Landrace prepubertal gilts for 35 d. Concentrations (as-fed basis) of the indicator toxins deoxynivalenol (DON) and zearalenone (ZON), respectively, were 210 and 4 (control--group I), 3,070 and 88 (group II), 6,100 and 235 (group III), and 9,570 and 358 microg/kg (group IV). No signs of hyperestrogenism or uterotrophic effects were observed because of dietary treatments. The feeding of mycotoxin-contaminated diets did not cause gross pathological findings in the spleens of animals. In vivo, no inhibitory effects were detected on concanavalin A-stimulation of blood lymphocytes; however, the proliferation rate of splenocytes was inhibited (P < 0.05) in pigs fed the diet with the highest DON/ZON concentration. With in vitro studies, lower proliferation rates of blood lymphocytes and splenocytes preexposed to DON were detected. Serum IgA concentrations of pigs in group II were increased (P < 0.05) compared with the baseline value before feeding the DON/ZON diet. The histopathological data indicated elevated (P < 0.05) iron staining in the red pulp of spleens in gilts from groups I to IV after 35 d of feeding. The presence of hemosiderin particles in the spleen sections was confirmed by transmission electron microscopic investigation. Together, the results provide evidence of spleen dysfunction (hemosiderosis) in the absence of clinical signs, especially in pigs fed higher concentrations (groups III and IV) of Fusarium toxin-contaminated wheat.  相似文献   

6.
Two feeding experiments with female weaned piglets were carried out applying a complete two by two factorial design to investigate the effects of the dietary inclusion of 500 g/kg Fusarium toxin contaminated maize (8.6 mg/kg deoxynivalenol (DON); 1.2 mg/kg zearalenone (ZON)) and of 4 g/kg aluminosilicate (AS) as a detoxifying agent. The resulting four diets were fed ad libitum to a total of 80 piglets (20 piglets per group, allotted to a total of 20 pens) covering a live weight range of 10.5 +/- 1.3 to 27.5 +/- 4.4 kg in experiment 1, and to a total of 48 piglets (12 piglets per group, allotted to 12 pens) covering a live weight range of 9.7 +/- 1.8 to 21.4 +/- 4.8 kg in experiment 2. The animals of experiment 1 were slaughtered on days 34-36 of feeding the experimental diets. The mycotoxin analyses revealed that the control maize also contained considerable concentrations of Fusarium toxins, but the differences in DON and ZON concentrations between control and contaminated diets were sufficiently high to demonstrate both dose-related toxin effects. Voluntary feed intake and live weight gain of the animals were significantly reduced by the inclusion of Fusarium toxin contaminated maize into the diets in both experiments, while a significantly decreased feed to gain ratio was found in experiment 1. Furthermore, the relative weight of the uterus, stomach and heart of the animals fed the contaminated maize containing diets were significantly increased. Serum albumin concentrations and the activity of GLDH were significantly reduced by the inclusion of the contaminated maize. The addition of AS to the Fusarium toxin contaminated diets did not prevent or alleviate any of the mentioned effects. Moreover, the feed intake tended to be decreased by this supplementation in both experiments, while a significantly decreased feed to gain ratio was indicated for this factor in experiment one as well. The serum concentration of albumin and the activities of ASAT and gammaGT were significantly increased if AS was present in the diets while serum concentration of cholesterol and alpha-tocopherol were decreased significantly or in tendency, respectively. The concentrations of retinol and retinyl esters in liver and serum were not altered by the treatments. The analysed concentrations of zearalenone (ZON) and its metabolites in the bile fluid clearly indicated the differences in dietary ZON concentrations and showed that AS was ineffective in preventing the absorption of the toxin from the gastrointestinal tract. Also, serum concentrations of DON reflected the DON intake prior to sampling. However, there were no differences between groups fed diets with or without AS which also suggests the inefficacy of the tested AS in preventing the DON absorption. The present investigations failed to demonstrate a detoxifying capacity of the tested additive and emphasize the general necessity for a critical verification of detoxifying agents in vivo.  相似文献   

7.
Based on a feeding trial using 27 lactating "Simmental-cows" the effect of naturally contaminated feed with deoxynivalenol (DON) as well as zearalenone (ZON) regarding production parameters was examined. 3 groups of cows according to lactation number, milk yield (kg ECM) and body mass were used. The average daily intake of DON in group K was 12.4 mg, in group T 14.1 mg and in group M 14.3 mg and ZON in group K was 12.4 mg, in group T 0.67 mg and in group M 0.68 mg respectively. The feed of animals of group M was supplemented with "Mycofix Plus" as mycotoxin inactivator. The red and white blood picture including the thrombocytes were in all groups within the normal range. Concerning enzymes (GGT, AP) and metabolites (GLUC, TBIL, UREA, CREA) the mean values of the 3 groups were in the normal range. Slightly increased were the mean values of all groups in respect to the AST- and GLDH-activities. Volatile fatty acids of the rumen content were significantly highest in group M, also the number of dead rumen infusoria was significantly decreased, but the counts of small sized infusoria increased. The study has shown that "Mycofix Plus" might be able to enhance the activity of rumen flora concerning detoxification of mycotoxins in feed of dairy cows.  相似文献   

8.
A feeding trial using 220 weaner pigs which comprised two experimental series was conducted to investigate the effects of diets contaminated with the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) and to test the hypothesis that apple pomace acts as an antidote to these mycotoxins. Two diets without contaminated wheat, containing either no pomace or 8% pomace, and two diets with naturally contaminated wheat (3.2 mg DON and 0.06 mg ZON, and 2.1 mg DON and 0.25 mg ZON per kg diet in series 1 and 2 respectively), containing either no pomace or 8% pomace were fed ad libitum for 5 weeks. Mycotoxin exposure lowered feed intake (p < 0.01) and growth (p = 0.05), and tended to decrease the energy conversion ratio (p = 0.06). Although the intake of apple pomace did not increase feed intake, it increased the growth rate (p = 0.04), mainly by restoring growth in the presence of mycotoxins (p = 0.08 for the interaction mycotoxin x pomace). In the first experimental series, the animals were immunized with a parvovirus vaccine. The percentage of seroconverting animals did not differ between the treatments (p = 0.56), which indicates that DON did not affect the humoral immune response. In the second experimental series, female piglets fed the contaminated diets had heavier uteri than piglets fed the uncontaminated diets (p < 0.01), regardless of pomace supplementation. The results show that pomace may alleviate the negative effect of DON on growth but does not counteract the hormonal effects of ZON.  相似文献   

9.
1. Diets with increasing proportions of Fusarium-toxin-contaminated wheat were fed to Pekin ducks for 49 d in order to titrate the lowest effect level. Dietary deoxynivalenol (DON) and zearalenone (ZON) concentrations were successively increased up to 6 to 7 mg/kg and 0.05 to 0.06 mg/kg, respectively. 2. Feed intake, live weight gain and feed to gain ratio were not influenced by dietary treatment. 3. Gross macroscopic inspection of the upper digestive tract did not reveal any signs of irritation, inflammation or other pathological changes. The weight of the bursa of Fabricius, relative to live weight, decreased in a dose-related fashion. Activities of glutamate dehydrogenase and gamma-glutamyl-transferase in serum were either unaffected or inconsistently affected by dietary treatments. 4. Concentrations of DON and of its de-epoxydised metabolite in plasma and bile were lower than the detection limits of 6 and 16 ng/ml, respectively, of the applied high performance liquid chromatography (HPLC) method. 5. ZON or its metabolites were not detectable in plasma and livers (detection limits of the HPLC method were 1, 0.5 and 5 ng/g for ZON, alpha-zearalenol (alpha-ZOL) and beta-zearalenol (beta-ZOL), respectively). Concentrations of ZON, alpha-ZOL and beta-ZOL in bile increased linearly with dietary ZON concentration. The mean proportions of ZON, alpha-ZOL and beta-ZOL of the sum of all three metabolites were 80, 16 and 4%, respectively. 6. Taken together, it can be concluded that dietary DON and ZON concentrations up to 6 and 0.06 mg/kg, respectively, did not adversely affect performance and health of growing Pekin ducks.  相似文献   

10.
A dose response study was carried out with piglets to examine the effects of increasing amounts of Fusarium toxins in the diet on performance, clinical serum characteristics, organ weights and residues of zearalenone (ZON) and deoxynivalenol (DON) and their metabolites in body fluids and tissues. For this purpose, Fusarium toxin contaminated maize (1.2 mg ZON and 8.6 mg DON per kg maize) was incorporated into a maize based diet for piglets at 0, 6, 12.5, 25 and 50% at the expense of control maize. The experimental diets were tested on 100 female piglets allotted to 20 boxes (five animals per box) covering a body weight range of 12.4 +/- 2.2 kg to 32.5 +/- 5.6 kg. Voluntary feed intake and, consequently, body weight gain of the animals receiving the highest proportion of Fusarium toxin contaminated maize were significantly decreased while the feed conversion ratio was not affected by the treatment. The mean weight of the uterus related to the body weight of the animals of the same group was increased by almost 100% as compared to the control. For this group, significantly decreased values of total serum protein were determined, while the serum activity of the liver enzyme glutamate dehydrogenase and the serum concentration of the follicle stimulating hormone were decreased for all treatment groups receiving 6% contaminated maize or more in the diet. Serum concentrations of immuneglobulins were not consistently altered by the treatment. Corresponding to the dietary exposure, increasing concentrations of ZON and alpha-zearalenol were detected in the bile fluid, liver and in pooled urine samples. The metabolite beta-zearalenol was detected only in bile fluid. The total concentration of ZON plus its metabolites in bile fluid correlated well with the diet contamination (r = 0.844). DON was found in serum, bile fluid and pooled urine samples while de-epoxy-DON was detected only in urine. The serum concentration of DON correlated well with the respective toxin intake 3-4 h prior to slaughtering (r = 0.957). For all mentioned analyses of residues it has to be noted that toxin residues were detectable even if negligible concentrations were present in the diet.  相似文献   

11.
Two experiments were carried out with male broilers to examine excretion kinetics of zearalenone (ZON) and its metabolites and their occurrence in blood plasma and bile fluid after a single oral dose of ZON (approximately 6 micrograms/kg BW) from naturally contaminated wheat (406 micrograms ZON per kg). In addition, this ZON bolus was administered either in the absence or presence of a detoxifying agent (Mycofix-Plus, Biomin GmbH, Herzogenburg, Austria). Specimens were sampled after administration of the zearalenone bolus at different times of up to 48 h. Excretion of zearalenone and alpha-zearalenol as the only detectable metabolite of ZON peaked at approximately 6.5 h after administration of the bolus. Cumulative excretion of both substances amounted to approximately 58% of ZON intake after 48 h, when a plateau was achieved. The incomplete recovery could have been due to a partial total degradation of ZON in the digestive tract, undetected sulfate conjugates of ZON or its metabolites, to other unknown and undetected metabolites or to incomplete analytical recovery from the matrix, and needs to be examined further. Peak concentrations of zearalenone and alpha-zearalenol in bile were detected in the time period of approximately 2 to 6 h after bolus, whereas ZON and metabolite concentrations in blood plasma were around or lower than the detection limits. Mycofix-Plus supplementation seemed to have only minor or no effects on the parameters examined.  相似文献   

12.
432只艾维因肉仔鸡用于研究小麦基础日粮中添加木聚糖酶(320FXU/kg)或添加750U/kg植酸酶降低日粮中0.08%的非植酸磷后,对生长性能、日粮表观代谢能、粗蛋白和植酸磷表观消化率的影响。试验结果表明:无论是单一添加木聚糖酶或植酸酶,还是同时添加这两种酶,都能提高1-6周龄肉仔鸡的增重和饲料转化率,降低死亡率。添加木聚糖酶可提高肉仔鸡小麦日粮的表观代谢能2.14%,增加氮的存留量2.58%。750U/kg的植酸酶完全可以降低肉仔鸡小麦日粮中0.08%非植酸磷。添加植酸酶的处理组可提高植酸磷的表观消化率43.25%,减少植酸磷排泄量55.0%。植酸酶和木聚糖酶对全期饲料转化率和植酸磷的表观消化率表现有明显的正互作效应(P<0.05)。  相似文献   

13.
1. The aim of the study was to examine the response of male broilers of different age categories to different dietary ideal protein (IP) concentrations and to compare the effects to IP recommendations based on single lysine (Lys) requirement studies from the literature. 2. Two experiments were carried out, in which diets containing different IP concentrations (9.0 to 14.4g apparent faecal digestible (AFD) Lys/kg) were fed to male broilers from 14 to 34 (Exp. 1) and 28 to 41 d of age (Exp. 2). The diets (12.88MJ AMEN/kg) were prepared by the dilution technique. The effect of dietary IP concentrations on weight gain, feed intake, feed conversion efficiency (FCE) and slaughter characteristics were studied in both experiments. 3. In Exp. 1, weight gain and FCE increased linearly and fat concentration in the carcase decreased with increasing IP concentration. In Exp. 2, weight gain and FCE improved exponentially, whereas breast meat yield improved linearly with increasing dietary IP concentration. On the basis of these results, it was concluded that the weight gain and FCE of male broilers respond to higher dietary IP levels than would be expected from single lysine requirement studies in the literature.  相似文献   

14.
Thirty-two boars were fed diets containing 0, 3, 6 or 9 ppm zearalenone from 32 d of age up to 145 or 312 d of age. Rate of gain, feed intake and gain:feed were not significantly different among treatments. Feeding of diets containing 9 ppm zearalenone did not affect the libido in seven boars. There was a tendency for boars fed 9 ppm dietary zearalenone to produce lower total and gel free volumes of semen, with lower total motile sperm; however, only the percent motility of the sperm was reduced (P less than .05).  相似文献   

15.
玉米赤霉烯酮的代谢、毒性及其预防措施   总被引:3,自引:0,他引:3  
玉米赤霉烯酮(ZEA)是由镰孢属真菌产生的类雌激素毒素.由于气候条件不同,食品和饲料中ZEA浓度差异很大(从几个mg/kg至几千个mg/kg).本文综述了ZEA的吸收、代谢和生物转化机制,ZEA的生殖毒性、细胞毒性、免疫毒性和遗传毒性,并且从预防土壤中镰孢菌及其相关霉菌的污染、收获和收获后真菌毒素的控制、污染颗粒的物理...  相似文献   

16.
1. The aim of the present experiment was to examine the influence of particle size and xylanase supplementation on the performance, energy utilisation, and gross morphological and histological parameters of the digestive tract of broiler starters fed wheat-based diets. The experimental design was a 2 x 2 factorial arrangement of treatments evaluating two wheat particle sizes (medium and coarse) and two levels of xylanase supplementation (without or with 1000 xylanase units/kg diet). The two particle sizes were achieved by grinding the whole wheat in a hammer mill to pass through 3 and 7 mm screens, respectively. Broiler starter diets, based on wheat and soybean meal, were formulated and each diet was fed ad libitum to 6 pens of 8 male broilers each from d 1 to 21 post-hatch. 2. Wheat particle size had no effect on the performance of broilers. Xylanase supplementation had no effect on weight gain and feed intake. However, a significant particle size x xylanase interaction was observed for feed per unit gain with xylanase lowering feed per gain only in the coarse particle size diet. Xylanase supplementation improved the nitrogen-corrected apparent metabolisable energy at both particle sizes. 3. Xylanase supplementation decreased the relative weight and relative length of all gut components. Villus height and crypt depth and total extent of the mucosal layer were unaffected by both wheat particle size and xylanase supplementation. 4. The apparent viscosity of intestinal digesta, determined over the physiological range of shear rates, was not influenced by xylanase addition or particle size. 5. The findings of this study suggest that the effectiveness of exogenous xylanase in broiler diets is influenced by wheat particle size.  相似文献   

17.
A feeding trial was conducted to evaluate the effects of moderate dietary concentrations of deoxynivalenol (DON) during a 21-day feeding experiment on the performance of broilers. Fifteen 1-day-old broiler chicks were randomly divided into two groups. The control group was fed non-contaminated diet. Another group of broilers was fed a diet naturally contaminated with 5 mg DON/kg diet. Deoxynivalenol had no effect (p > 0.05) on feed consumption, feed conversion, body-weight gain, live body weight or mortality. The absolute and relative weight of the organs (gizzard, pancreas, heart, spleen, colon and caecum) were not altered by the dietary inclusion of DON contaminated grain. However, both the absolute and relative weight of small intestine was decreased (p < 0.01) in DON fed broilers compared to the controls. No gross lesions were detected in any of the organs of birds fed contaminated wheat during the feeding trial. The microscopic examination revealed that, the height and the width of villi in duodenum decreased (p < 0.05) in birds fed DON contaminated wheat compared to controls. On the other hand the height and the width of jejunum villi were not affected (p > 0.05). This study indicates that feeding DON for 21 days to broiler chickens at a concentration of up to 5 mg/kg of diet influenced the weight of the small intestine as well as intestinal histology, especially the duodenum, as evidenced by shorter and thinner villi. In conclusion, diets with DON contamination below levels that induce negative impact on health and performance could affect small intestinal morphology in broilers.  相似文献   

18.
1. The aim of the present experiment was to examine the influence of whole wheat inclusion and a blend of essential oils (EO; cinnamaldehyde and thymol) supplementation on the performance, nutrient utilisation, digestive tract development and ileal microbiota profile of broiler chickens. 2. The experimental design was a 2 × 2 factorial arrangement of treatments evaluating two wheat forms (ground wheat [GW] and whole wheat [WW]; 100 and 200 g/kg WW replacing GW during starter [1 to 21 d] and finisher [22 to 35 d] diets respectively) and two levels of EO inclusion (0 or 100 g/tonne diet). All dietary treatments were supplemented with 2000 xylanase units/kg feed. Broiler starter and finisher diets based on wheat and soybean meal were formulated and each diet fed ad libitum to 6 pens of 8 male broilers. 3. During the trial period (1-35 d), wheat form had no significant effect on weight gain or feed intake. However, WW inclusion tended (P = 0.06) to improve feed per gain. Essential oil supplementation significantly improved weight gain in both diets, but the improvements were greater in the GW diet as indicated by a significant wheat form × EO interaction. 4. Main effects of wheat form and EO on the relative weight, length and digesta content of various segments of the digestive tract were not significant. Significant interactions, however, were found for relative gizzard and caecal weights. Essential oil supplementation significantly increased the relative gizzard weight and lowered relative caecal weight in birds fed on the GW based diet, but had no effect in those fed on the WW based diet. 5. Whole wheat inclusion and EO supplementation significantly improved apparent ileal nitrogen digestibility. Apparent ileal digestible energy was not significantly influenced by the dietary treatments. 6. Ileal microbiota profiling, using denaturing gradient gel electrophoresis, showed that the ileal microbiota composition was influenced by feed form. The mean numbers of bacterial species in the ileal contents of birds fed on the GW diet supplemented with EO tended (P = 0.07) to be higher than those of the ileal contents of birds fed on unsupplemented GW based diet. 7. The present data suggested that dietary addition of EO improves broiler weight gain and ileal nitrogen digestibility both in GW and WW based diets, but that the magnitude of the response to EO for weight gain was greater in GW based diet. Whole wheat feeding was found to be beneficial in terms of feed efficiency.  相似文献   

19.
小麦作为主要能量作物之一在粮食工业中已得到广泛应用,其在饲料工业上的应用也越来越受到人们重视,但其含有的抗营养因子在一定程度上限制了其在饲料工业中的应用。小麦中主要的抗营养因子是阿拉伯木聚糖,而向小麦型基础日粮中添加木聚糖酶是消除其抗营养特性的有效办法。文中介绍了小麦型基础日粮中木聚糖的抗营养特性及其对肉鸡生产性能的负面影响,木聚糖酶的作用机理及在肉鸡小麦型日粮中添加木聚糖酶的作用效果,以期为小麦合理地应用于肉鸡日粮提供参考。  相似文献   

20.
本试验旨在研究在2种能量水平饲粮中添加大豆卵磷脂乳化剂对肉鸡生长性能、养分利用率和血清生化指标的影响。试验采用2×2因子完全随机区组试验设计,将960只1日龄科宝500白羽肉公鸡随机分为4组,每组6个重复,每个重复40只鸡。各组试验鸡分别饲喂2个能量水平和2个乳化剂添加水平组成的试验饲粮,其中代谢能分别为12.13和11.92 MJ/kg(1~21日龄)、12.96和12.65 MJ/kg(22~49日龄),乳化剂添加水平分别为0和265 mg/kg(1~21日龄)、0和400 mg/kg(22~49日龄)。试验测定肉鸡生长性能,能量、干物质、粗蛋白质和粗脂肪表观利用率,以及血糖、血脂和胆汁酸含量。结果表明:肉鸡采食正常能量饲粮前期(1~21日龄)平均日增重极显著高于低能量饲粮(P<0.01),肉鸡全期(1~49日龄)采食添加乳化剂的低能量饲粮料重比能达到正常能量饲粮水平;饲粮添加乳化剂有提高平均日增重和饲粮粗脂肪和能量表观利用率的趋势,可促进胆汁分泌,能显著降低前期及全期料重比(P<0.05)。结果显示,降低饲粮能量显著降低1~21日龄肉鸡平均日增重,提高1~21日龄和1~49日龄料重比;饲粮添加乳化剂能够改善饲料利用率,特别是在1~21日龄肉鸡低能量饲粮中效果更明显。  相似文献   

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