STUDY ON RELATIONS BETWEEN HEAVY-DISASTER-PERIOD OF FOREST FIRE ACTIVITY AND SUNSPOT ACTIVITY, SSTA

TheprojectwassupportedbyChinaNaturalScienceFund.INTRoDUCTIoNOursocietyhascomeintoaperiodofhighdevelopedscienceandtechnology,nevertheless,it'sapitythatmankindhasn'tfreedhimselffrompassiveandblindcondi-tionthatforestfirewaspreventedandcon-trolledonlargescale.Particufarly,sofarthebasiclawsofinter-annualchangesofforestfirehasnotbeenknown.Itremainsperplexingwhyheavy-disaster-periodofforestfire(HDPFF)inacertainregionreappearseveryafewyearsandlastsforl-2yearswithgreatlossofforestresource.A1th…     

鸭儿芹精油成分、抗氧化与抑菌活性研究

为给鸭儿芹的综合利用提供科学依据,以鸭儿芹茎、叶为原料,采用水蒸气蒸馏法提取鸭儿芹精油,利用气相色谱-质谱联用技术(GC-MS)对鸭儿芹精油成分进行了分析,利用DPPH、ABTS自由基清除能力试验与FRAP试验及打孔法抑菌试验对其精油的抗氧化抗菌活性进行了分析。结果表明:(1)精油成分方面,从鸭儿芹精油中共分离出32个峰,占总离子峰的93.75%,共鉴定出30种化合物,其主要成分分别为α-芹子烯(42.01%)、β-芹子烯(19.86%)、(Z)-β-金合欢烯(12.76%)、镰叶芹醇(4.16%)、α-没药醇(3.93%)等;(2)抗氧化能力方面,当鸭儿芹精油浓度由19μg/m L上升到38μg/m L时,DPPH反应液中Trolox的当量由0.003μmol上升到0.007μmol,ABTS反应液中Trolox的当量由0.069μmol上升到0.074μmol,FRAP反应液中Trolox的当量由0.225μmol上升到0.280μmol,当精油浓度在一定范围内,其DPPH清除能力、ABTS自由基清除能力及铁离子还原抗氧化能力与其浓度间均呈量效关系,且均呈正相关效应,表明鸭儿芹精油具有良好的抗氧化能力;(3)抗菌活性方面,当鸭儿芹精油浓度为1 280 mg/m L时,金黄色葡萄球菌的抑菌圈直径可达7.05 mm,表现出一定的抑菌活性,且其对金黄色葡萄球菌的抑菌效果显著优于其对大肠杆菌的抑菌效果。     

Antimicrobial activity and cytotoxicity of Cirsium tenoreanum

The methanol and ethyl acetate extracts of the aerial parts of Cirsium tenoreanum, have been evaluated for their phytochemical constituents and antibacterial and cytotoxic properties. Three flavonoids, apigenin, quercetin-3-O-galactoside and kaempferol-3-O-ramnoside, were isolated. The ethyl acetate extract showed a good antiproliferative activity.     

Molluscicidal and antimicrobial activity of Solanum aculeastrum

The methanolic extract of the fresh root bark and berries of Solanum aculeastrum showed significant activity against host snails of schistosomiasis. The berries extract was more potent with 100% snail kill at 50 ppm. Fractionation increased activity with 100% mortality at 20 ppm. The aqueous and methanolic extracts of the berries showed moderate antimicrobial activity, increasing by fractionation.     

Antimicrobial and cytotoxic activity of Ruta graveolens

The methanol, petroleum ether, ethyl acetate and water-methanol extracts of Ruta graveolens were found to possess antimicrobial and cytotoxic activities.     

Antinephritis and radical scavenging activity of prenylflavonoids

Antinephritis activity of 5 prenylflavonoids similar to glabridin (1-5), isolated from Morus alba, Artocarpus communis, Glycyrrhiza uralensis and G. inflata, was evaluated in mice with glomerular disease (Masugi-nephritis). Oral administrations of artonin E (2) or licochalcone A (4) for 10 days (30 mg kg(-1) day(-1)) reduced the amount of urinary protein excretion compared to nephritic mice. ESR spectroscopy demonstrated that morusin (1) and licorisoflavan A (5) increased the radical intensity of sodium ascorbate by about two times. Morusin, licoricidin (3), licochalcone A and licorisoflavan A showed weak scavenging activity against superoxide anion radical.     

Antimicrobial activity and cytotoxicity of Ramalina farinacea

The water, ethanol, chloroform and n-hexane extracts of the lichen Ramalina farinacea have been evaluated for their phytochemical constituents, antibacterial, antifungal, and cytotoxic properties.     

Antimicrobial activity and cytotoxicity of Trapa bispinosa

The extracts of Trapa bispinosa showed interesting antimicrobial activity against Gram-positive and Gram-negative test organisms and significant cytotoxic activity.     

Phytogrowth-inhibitory and antibacterial activity of Verbascum sinuatum

The methanolic extract of Verbascum sinuatum inflorescences and isolated compounds were tested for their antibacterial activity against 13 Gram(+) and Gram(-) bacteria and for their allelopathic activity against radish.     

竹叶黄酮的生理与药理活性

介绍了竹子的药用价值和竹叶中的黄酮类化合物的药用历史。研究表明,竹叶黄酮有抗脂质过氧化、扩张冠脉血管和对抗心肌梗塞等作用。并就竹叶黄酮对天然抗氧化剂在食品添加剂中,如肉类、水产品和果汁饮料的应用前景进行了阐述。     

Anti-inflammatory and analgesic activity of Bouchea fluminensis

Dried leaves extract from Bouchea fluminensis was assessed in anti-inflammatory (mouse paw edema) and analgesic models (acetic acid-induced writhings and hot plate). Oral pretreatment of animals with a crude mixture (IG) and a purified mixture of ursolic, oleanolic and micromeric acids (IG-59) at doses ranging from 1 to 30 mg/kg, significantly inhibited carrageenin-induced edema formation. At the same doses, IG and IG-59 also exhibited peripheral and central analgesic activity. It seems that B. fluminensis triterpenes develop their analgesic effect through central opioid receptors, due to the observation that naloxone reverted analgesic activity on the hot plate model.     

Antioxidant and anti-inflammatory activity of Emilia sonchifolia

Fresh juice and methanolic extract of Emilia sonchifolia leaves were found to be potent inhibitors of hydroxyl radical formation and superoxide radical generation in vitro. The methanolic extract inhibited the carrageenan-induced oedema.     

Antinociceptive and antidiarrhoeal activity of Zanthoxylum rhetsa

The methanolic extract of the Zanthoxylum rhetsa Roxb. stem bark, given by oral route to mice at doses of 250 and 500 mg/kg, significantly reduced the abdominal contraction induced by acetic acid and the diarrhoeal episodes induced by castor oil in mice.     

Antimicrobial activity and cytotoxicity of Aerva lanata

Aerva lanata whole plant showed interesting antimicrobial activities (ethyl acetate and methanol extracts) and significant cytotoxic properties (petroleum ether, ethyl acetate and methanol extracts).     

Antibacterial and antifungal activity of Erigeron breviscapus

The antibacterial and antifungal properties of the ethanol extract of Erigeron breviscapus whole plant was evaluated. The extract showed a moderate antibacterial activity and a high antifungal activity.     

Antimicrobial activity and constituents of Coccoloba acrostichoides

The ethanol extract and fractions from Coccoloba acrostichoides aerial parts were assayed for in vitro antimicrobial activity. The extract was active against the assayed bacteria while most of the fractions also inhibited fungal growth, especially the n-hexane and EtOAc fractions. The isolated beta-sitosterol and betulin were tested, being the last one active against Fusarium oxysporum.     

Anticandidal activity of curcumin and methyl cinnamaldehyde

Cinnamaldehyde, its derivatives and curcumin are reported to have strong antifungal activity. In this work we report and compare anticandidal activity of curcumin (CUR) and α-methyl cinnamaldehyde (MCD) against 38 strains of Candida (3; standard, fluconazole sensitive, 24; clinical, fluconazole sensitive, 11; clinical, fluconazole resistant). The minimum inhibitory concentrations (MIC₉₀) of CUR ranged from 250 to 650 μg/ml for sensitive strains and from 250 to 500 μg/ml for resistant strains. MIC₉₀ of MCD varied between 100 and 250 μg/ml and 100–200 μg/ml for sensitive and resistant strains, respectively. Higher activity of MCD as compared to CUR was further reinforced by spot assays and growth curve studies. At their respective MIC₉₀ values, in the presence of glucose, average inhibition of H⁺-efflux caused by CUR and MCD against standard, clinical and resistant isolates was 24%, 31%, 32% and 54%, 52%, 54%, respectively. Inhibition of H⁺-extrusion leads to intracellular acidification and cell death, average pHi for control, CUR and MCD exposed cells was 6.68, 6.39 and 6.20, respectively. Scanning electron micrographs of treated cells show more extensive damage in case of MCD. Haemolytic activity of CUR and MCD at their highest MIC was 11.45% and 13.00%, respectively as against 20% shown by fluconazole at typical MIC of 30 μg/ml. In conclusion, this study shows significant anticandidal activity of CUR and MCD against both azole-resistant and sensitive clinical isolates, MCD is found to be more effective.     

Antiplasmodial activity and cytotoxicity of Albertisia delagoensis

Leaves and rhizome methanol extracts of Albertisia delagoensis tested positive against Plasmodium falciparum, with a very low cytotoxic activity in leaves against the Graham cell line.     

Antimicrobial activity and cytotoxicity of Zanthoxylum budrunga

The petroleum ether, chloroform and methanol extracts of the leaves and barks of Zanthoxylum budrunga have been evaluated for their antibacterial, antifungal and cytotoxic properties.     

Analgesic and anti-inflammatory activity of Leonurus sibiricus

The methanolic extract of Leonurus sibiricus aerial parts injected intraperitoneally at dose of 250 and 500 mg/kg showed a significant analgesic effect in acetic acid-induced writhing in mice. Moreover, when given orally to rats at dose of 200 and 400 mg/kg, it showed a significant anti-inflammatory activity against carrageenin induced rat paw edema in rats.