Divergent selection for postweaning feed conversion in beef cattle: predicted response based on an index of feed intake and gain vs fee: gain ratio

As part of a divergent selection experiment (high vs low feed conversion) designed to obtain realized genetic parameter estimates for postweaning feed conversion, 35 Angus bull calves were selected each year from 1979 through 1983 to be fed in a 140-d postweaning performance test. From these 35 individually-fed bulls, the three most efficient and three least efficient (in terms of kilograms of total digestible nutrients required per kilogram of gain) were selected each year to each be mated to approximately 20 purebred Angus cows in a test herd. In the last 2 yr of the experiment, feed:gain ratios were adjusted for differences in maintenance requirements before selection. An alternative to selection based on feed/gain or adjusted feed/gain would have been to select on an index of feed intake and gain (Index3 = -1.0 feed intake + 3.87 gain) where feed intake was either unadjusted or adjusted (AdjIndex3) for differences in maintenance requirements. Residual correlations (year effects removed) among the four selection critera were large ([r[ greater than or equal to .76; P less than .01) as were correlations among ranks of the bulls based on the four selection criteria ([r[ greater than or equal to .75). Predicted genetic change for fee:gain ratio in both the high and low directions was greatest when selection was based on feed:gain ratio or Index3. Genetic changes expected to result from selection for feed:gain ratio or Index3 were similar, as were genetic changes expected due to selection for adjusted feed:gain ratio or AdjIndex3.(ABSTRACT TRUNCATED AT 250 WORDS)     

Genetic and phenotypic variance and covariance components for feed intake, feed efficiency, and other postweaning traits in Angus cattle.

Records on 1,180 young Angus bulls and heifers involved in performance tests were used to estimate genetic and phenotypic parameters for feed intake, feed efficiency, and other postweaning traits. The mean age was 268 d at the start of the performance test, which comprised 21-d adjustment and 70-d test periods. Traits studied included 200-d weight, 400-d weight, scrotal circumference, ultrasonic measurements of rib and rump fat depths and longissimus muscle area, ADG, metabolic weight, daily feed intake, feed conversion ratio, and residual feed intake. For all traits except the last five, additional data from the Angus Society ofAustralia pedigree and performance database were included, which increased the number of animals to 27,229. Genetic (co)variances were estimated by REML using animal models. Direct heritability estimates for 200-d weight, 400-d weight, rib fat depth, ADG, feed conversion,and residual feed intake were 0.17 +/- 0.03, 0.27 +/- 0.03, 0.35 +/- 0.04, 0.28 +/- 0.04, 0.29 +/- 0.04, and 0.39 +/- 0.03, respectively. Feed conversion ratio was genetically (r(g) = 0.66 ) and phenotypically (r(p) = 0.53) correlated with residual feed intake. Feed conversion ratio was correlated (r(g) = -0.62, r(p) = -0.74) with ADG, whereas residual feed intake was not (rg = -0.04, r(p) = -0.06). Genetically, both residual feed intake and feed conversion ratio were negatively correlated with direct effects of 200-d weight (r(g) = -0.45 and -0.21) and 400-d weight (r(g) = -0.26 and -0.09). The correlations between the remaining traits and the feed efficiency traits were near zero, except between feed intake and feed conversion ratio (r(g) = 0.31, r(p) = 0.23), feed intake and residual feed intake (r(g) = 0.69, r(p) = 0.72), and rib fat depth and residual feed intake (r(g) = 0.17, r(p) = 0.14). These results indicate that genetic improvement in feed efficiency can be achieved through selection and, in general, correlated responses in growth and the other postweaning traits will be minimal.     

Genetic and phenotypic parameter estimates for feed intake and other traits in growing beef cattle, and opportunities for selection

Growth, feed intake, and temperament indicator data, collected over 5 yr on a total of 1,141 to 1,183 mixed-breed steers, were used to estimate genetic and phenotypic parameters. All steers had a portion of Hereford, Angus, or both as well as varying percentages of Simmental, Charolais, Limousin, Gelbvieh, Red Angus, and MARC III composite. Because the steers were slaughtered on various dates each year and the animals thus varied in days on feed, BW and feed data were adjusted to a 140-d feeding period basis. Adjustment of measures of feed efficiency [G:F or residual feed intake (RFI), intake adjusted for metabolic body size, and BW gain] for body fatness recorded at slaughter had little effect on the results of analyses. Average daily gain was less heritable (0.26) than was midtest BW (MBW; 0.35). Measures of feed intake had greater estimates of heritability, with 140-d DMI at 0.40 and RFI at 0.52; the heritability estimate for G:F was 0.27. Flight speed (FS), as an indicator of temperament, had an estimated heritability of 0.34 and a repeatability of 0.63. As expected, a strong genetic (0.86) correlation was estimated between ADG and MBW; genetic correlations were less strong between DMI and ADG or MBW (0.56 and 0.71). Residual feed intake and DMI had a genetic correlation of 0.66. Indexes for phenotypic RFI and genotypically restricted RFI (no correlation with BW gain) were compared with simple economic indexes incorporating feed intake and growth to elucidate expected selection responses under different criteria. In general, few breed differences were detected across the various measurements. Heterosis contributed to greater DMI, RFI, and MBW, but it did not significantly affect ADG, G:F, or FS. Balancing output (growth) with input costs (feed) is needed in practicing selection, and FS would not be recommended as an indicator trait for selection to change feed efficiency. An index including BW gain and RFI produced the best economic outcome.     

Divergent selection for immune responsiveness in chickens: estimation of realized heritability with an animal model.

With the aim of improving general disease resistance, chickens were divergently selected for their antibody titers 5 d after immunization with sheep red blood cells for nine generations. Selected and control lines differed significantly for primary and secondary responses after three generations. Heritability of the antibody titer was estimated by REML fitting an animal model using a derivative-free algorithm. The heritability estimate using data on all lines simultaneously was .31. Realized heritability of the antibody titer in the selected lines was estimated by using either the phenotypic cumulative response as the deviation from the control line or the mean breeding values obtained with an animal model. Values from the two methods were consistent, giving a realized heritability of .21 and .25 in the high and low lines, respectively. The genetic trend was not linear and the response to selection tended to accelerate over generations.     

Heritabilities and genetic correlations for postweaning growth and feed intake of beef bulls and steers

Data from studies conducted at Miles City, MT and Lethbridge, AB were pooled to evaluate genetic and environmental variation in feed intake (MEI), growth rate (ADG), MEI-to-gain ratio (M/G), final weight (FWT), and fat thickness (FAT). A total of 124 sires with an average of 4.25 progeny each were represented in the data. Restricted maximum likelihood methods were used to estimate within and between paternal half-sib estimates of variance and covariance. Heritabilities and genetic, phenotypic, and environmental correlations with inference to populations at 365 d of age were calculated from the estimates. Heritabilities were as follows: ADG, .38 +/- .16; MEI, .45 +/- .17; M/G, .26 +/- .15; FWT .25 +/- .15; and FAT .52 +/- .17. The genetic correlation of MEI with ADG was large (.73 +/- .13) and antagonistic to genetic improvement of M/G through selection for ADG. Efficient genetic improvement in M/G was found to depend on using either MEI or an indicator of composition of gain as selection criteria in addition to ADG. Selection to improve M/G using an index that included FWT and FAT, in addition to MEI and ADG, resulted in greater predicted response in ADG and lesser predicted response in MEI than the index of ADG and MEI alone.     

Genetic parameter estimates for postweaning traits of beef cattle in a stressful environment

Postweaning growth data, collected from a Hereford herd located in the Southwest, were used to estimate genetic parameters for weights and gains. The herd was maintained on unsupplemented range forage, and average weight losses from weaning to yearling age were 9% for bulls and 12% for heifers. Data were grouped into years with poor and good environments based on contemporary group means for gain from 8 to 12 mo. Postweaning growth data (12- and 20-mo weights, 8- to 12-mo gain and 12- to 20-mo gain) were analyzed by least squares methods with a model that included year of birth, sire within year of birth, age of dam and a covariate of age for 12- and 20-mo weights. Heritability estimates of 12- and 20-mo weights for bulls were .58 +/- .15 and .55 +/- .22 in good environments vs .32 +/- .11 and 1.09 +/- .15 in poor environments; for heifers these estimates were .19 +/- .08 and .35 +/- .12 in good environments vs .38 +/- .07 and .47 +/- .09 in poor environments. Heritability estimates of 8- to 12-mo and 12- to 20-mo gain for bulls were .32 +/- .14 and .51 +/- .24 in good environments vs .16 +/- .11 and .09 +/- .14 in poor environments; for heifers these estimates were .21 +/- .08 and .14 +/- .10 in good environments vs .10 +/- .06 and .44 +/- .10 in poor environments. Genetic correlations among the preweaning traits of birth and weaning weight and postweaning weight traits were positive and of a moderate to large magnitude, with the exception of birth and 12-mo weight in a poor environment (-.06 +/- .49). Genetic correlations between 8- to 12-mo gain and birth weight in poor environment and weaning weight in all environments were negative (range from -.06 +/- .33 to -.53 +/- .41). Genetic correlations among 12- and 20-mo weights were large and positive in all environments. Relationships among gains were more variable.     

Selection for weaning weight and postweaning gain in Hereford cattle. II. Response to selection

Single trait selection was practiced in three lines of Hereford cattle at two locations. Bulls were selected within sire families for increased weaning weight (WW) in the WW line (WWL), for postweaning gain (PG) in the PG line (PGL) and at random in the control line (CTL). Data include the performance of 2,467 calves produced from 1967 to 1981. Environmental effects were estimated from CTL (method I) and from multiple regression procedures (method II). Phenotypic and environmental time trends were negative for WW and generally were positive for PG. Estimated genetic gains for WW in WWL were 1.07 +/- .51 kg/yr in bulls and .62 +/- .36 kg/yr in heifers using method I and .50 +/- .31 kg/yr in bulls and .10 +/- .17 kg/yr in heifers using method II. Corresponding values for PG in PGL were .85 +/- .40 and 1.03 +/- .24 kg/yr in bulls and .30 +/- .28 and .37 +/- .12 kg in heifers. Correlated genetic gains for WW in PGL were larger than direct WW gains, whereas genetic gains for PG in WWL were smaller than direct PG gains. From method I, estimates of realized heritability (h2R) for WW were .31 +/- .18 in bulls and .22 +/- .13 in heifers. For PG, h2R was .31 +/- .13 in bulls and .06 +/- .12 in heifers. Using method II, h2R for WW was .09 +/- .08 in bulls and .02 +/- .07 in heifers. Corresponding values for PG were .29 +/- .10 and .11 +/- .08. Joint estimates of the realized genetic correlation between WW and PG were .69 +/- .18 and .46 +/- .31 for methods I and II, respectively. Variation in selection response was evaluated using quasi-replicates. Results of this study indicate that selection for PG improved both WW and PG faster than selection for WW.     

Genetic parameter estimates for serum insulin-like growth factor-I concentration and carcass traits in Angus beef cattle

Divergent selection for serum insulin-like growth factor-I (IGF-I) concentration began at the Eastern Ohio Resource Development Center (EORDC) in 1989 using 100 spring-calving (50 high line and 50 low line) and 100 fall-calving (50 high line and 50 low line) purebred Angus cows. Following weaning, bull and heifer calves were fed in drylot for a 140-d postweaning period. At the conclusion of the postweaning test, bulls not selected for breeding were slaughtered and carcass data were collected at a commercial abbatoir. At the time of this analysis, IGF-I measurements were available for 1,283 bull and heifer calves, and carcass data were available for 452 bulls. A set of multiple-trait, derivative-free, restricted maximum likelihood (MTDFREML) computer programs were used for data analysis. Estimates of direct heritability for IGF-I concentration at d 28, 42, and 56 of the postweaning period, and for mean IGF-I concentration were .32, .59, .31, and .42, respectively. Direct heritabilities for carcass traits ranged from .27 to 1.0, .26 to 1.0, and .23 to 1.0 when the age-, fat-, and weight-constant end points, respectively, were used, with marbling score having the smallest heritability and longissimus muscle area having the highest heritability in each case. Maternal heritability and the proportion of phenotypic variance due to permanent environmental effect of dam generally were < or = .21 for IGF-I concentrations and for carcass traits other than longissimus muscle area. Additive genetic correlations of IGF-I concentrations with backfat thickness, longissimus muscle area, hot carcass weight, marbling score, quality grade, and yield grade averaged -.26, .19, -.04, -.53, -.45, and -.27, respectively, when carcass data were adjusted to an age-constant end point. Bulls with lower IGF-I concentrations had higher marbling scores and quality grades, but also had higher backfat thickness and yield grades regardless of the slaughter end point. Serum IGF-I concentration may be a useful selection criterion when efforts are directed toward improvement of marbling scores and quality grades of beef cattle.     

Genetic and phenotypic relationships of feed intake and measures of efficiency with growth and carcass merit of beef cattle

Feed intake and efficiency of growth are economically important traits of beef cattle. This study determined the relationships of daily DMI, feed:gain ratio [F:G, which is the reciprocal of the efficiency of gain (G:F) and therefore increases as the efficiency of gain decreases and vice versa, residual feed intake (RFI), and partial efficiency of growth (efficiency of ADG, PEG) with growth and carcass merit of beef cattle. Residual feed intake was calculated from phenotypic regression (RFIp) or genetic regression (RFIg) of ADG and metabolic BW on DMI. An F1 half-sib pedigree file containing 28 sires, 321 dams, and 464 progeny produced from crosses between Alberta Hybrid cows and Angus, Charolais, or Alberta Hybrid bulls was used. Families averaged 20 progeny per sire (range = 3 to 56). Performance, ultrasound, and DMI data was available on all progeny, of which 381 had carcass data. Phenotypic and genetic parameters were obtained using SAS and ASREML software, respectively. Differences in RFIp and RFIg, respectively, between the most and least efficient steers (i.e., steers with the lowest PEG) were 5.59 and 6.84 kg of DM/d. Heritabilities for DMI, F:G, PEG, RFIp, and RFIg were 0.54 +/- 0.15, 0.41 +/- 0.15, 0.56 +/- 0.16, 0.21 +/- 0.12, and 0.42 +/- 0.15, respectively. The genetic (r = 0.92) and phenotypic (r = 0.97) correlations between RFIp and RFIg indicated that the 2 indices are very similar. Both indices of RFI were favorably correlated phenotypically (P < 0.001) and genetically with DMI, F:G, and PEG. Residual feed intake was tendentiously genetically correlated with ADG (r = 0.46 +/- 0.45) and metabolic BW (r = 0.27 +/- 0.33), albeit with high SE. Genetically, RFIg was independent of ADG and BW but showed a phenotypic correlation with ADG (r = -0.21; P < 0.05). Daily DMI was correlated genetically (r = 0.28) and phenotypically (r = 0.30) with F:G. Both DMI and F:G were strongly correlated with ADG (r > 0.50), but only DMI had strong genetic (r = 0.87 +/- 0.10) and phenotypic (r = 0.65) correlations with metabolic BW. Generally, the phenotypic and genetic correlations of RFI with carcass merit were not different from zero, except genetic correlations of RFI with ultrasound and carcass LM area and carcass lean yield and phenotypic correlations of RFI with backfat thickness (P < 0.01). Daily DMI had moderate to high phenotypic (P < 0.01) and genetic correlations with all the ultrasound and carcass traits. Depending on how RFI technology is applied, adjustment for body composition in addition to growth may be required to minimize the potential for correlated responses to selection in cattle.     

Association of serologic status for Neospora caninum and postweaning feed efficiency in beef steers.

OBJECTIVE: To determine the effects of serologic status for Neospora caninum on short-term weight gain, feed intake, and feed efficiency (feed intake/gain). DESIGN: Longitudinal observational study. ANIMALS: 34 weaned mixed-breed beef steers. PROCEDURE: Serologic status for N. caninum was determined for each steer on days 0 (weaning), 88, 116, 144, 172, and 200, using an agglutination test. Individual steer body weight was measured on days 0, 88, 116, 144, 172, 200, and 242 (slaughter). Daily feed intake was monitored from days 116 through 242. Serologic status was matched to animal performance for the period immediately following serum sample collection. A mixed mode, using repeated-measures with an unstructured covariance matrix, was used in the analysis. Breed, age, and pen effects were controlled for in the analysis. RESULTS: A reduction in average daily gain for the period following a positive serologic result was detected for the entire trial (6 measurements/steer). This may have been attributed to a significant impairment in feed efficiency rather than to an impairment in feed intake. Changes in serologic status in individual steers over time were common; additionally, the effects of serologic status on steer performance were also transitory. CONCLUSIONS AND CLINICAL RELEVANCE: Significant reductions in short-term weight gain and feed efficiency were associated with the presence of antibodies against N. caninum in postweaning beef steers.     

Breed means for average daily gain, feed conversion and intake of beef bulls during postweaning feedlot performance tests

Comparisons of ADG, feed/gain, daily feed intake and daily feed intake as percentage of body weight may be important to beef cattle producers and researchers in breed selection and computer modeling. Data evaluated were postweaning feedlot performance test records collected from 1967 to 1986 of 3,661 individually fed bulls. Bulls originated from University of Arkansas purebred herds, Fayetteville, and the University of Arkansas Cooperative Bull Tests at Fayetteville, Hope and Monticello. Data were analyzed separately for years 1967 to 1976 (P1) (n = 1,654) and 1977 to 1986 (P2) (n = 2,007). Breeds in P1 were Hereford (HH), Angus (AN), Charolais (CH), Polled Hereford (HP) and Santa Gertrudis (SG). Breeds in P2 were HH, AN, CH, HP, SG, Simmental (SM), Maine-Anjou (MA), Brangus (BN) and Beefmaster (BM). The model fitted included initial age, breed and test number (all P less than .01 except for initial age on ADG in P1). Test number included variation of year, location and season. Breed rankings from highest to lowest for ADG in P1 were CH, SG, HH, HP and AN and in P2 were MA, CH, SM, AN, HP, SG, HH, BN and BM. Breed rankings from highest to lowest for feed/gain in P1 were AN, SG, CH, HP and HH and in P2 were BM, BN, AN, SG, HP, SM, HH, MA and CH. Breeds highest to lowest for daily feed intake (as-fed basis) in P1 were CH, SG, AN, HP and HH and in P2 were SM, MA, CH, AN, BN, HP, SG, HH and BM.(ABSTRACT TRUNCATED AT 250 WORDS)     

Genetic and environmental parameters for mature weight in Angus cattle

Genetic and environmental variances and covariances and associated genetic parameters were estimated for weaning weight, asymptotic mature weight, and repeated mature weights. Data consisted of a set of weight measurements of 3,044 Angus cows born between 1976 and 1990. Mature weight was predicted by individually fitting Brody growth curves (asymptotic weight) and by using weights repeatedly measured after 4 yr of age. Variance and covariance components for mature weight were estimated by REML from a single-trait animal model with asymptotic weight, a two-trait animal model with asymptotic and weaning weight, and a two-trait animal model with repeated weights and weaning weight. Weaning and cow contemporary groups were defined as fixed effects. Random effects for weaning weight included direct genetic, maternal genetic, and permanent environmental effects; and for mature weight, direct genetic and repeated measurements (if in the model). Heritability estimates for weaning weight were similar for both two-trait models (.53 and .59). Estimates of heritability for mature weight were .44, .52, and .53 for the single-trait model with asymptotic weight, two-trait model with asymptotic weight, and two-trait model with repeated measures weights, respectively. The estimate of the genetic correlation between mature and weaning weight was higher for the repeated measures model (.85 vs. .63). A lower heritability estimate for mature weight from the single-trait model was likely due to postweaning culling. Therefore, a genetic evaluation of mature weight from field data should include a trait recorded earlier in life that is less subjected to selective data reporting.     

Selection in Hereford cattle. II. Expected and realized response

Data from 14 inbred lines and 14 linecross groups of Hereford cattle at the San Juan Basin Research Center, Hesperus, were used to evaluate expected and realized response in birth and weaning traits and postweaning traits in males and females over a 28-yr period. There were large differences in the means and variances of the performance traits among the inbreds and linecrosses, with the inbreds showing inbreeding depression and greater variability among lines, while the linecrosses manifested within-breed heterosis. Except for gain from weaning to 12 mo, in females, genetic progress was expected in all traits studied, mainly due to sire selection. Regressions of annual trait means on years indicated positive phenotypic trends in the inbreds for heart girth circumference at birth, adjusted weaning weight (adjusted for inbreeding), weaning score, final weight, feed consumption and the yearling weights and gains in females. Changes were negative for other traits. In the linecross group phenotypic trends were positive in all traits except heart girth circumference, weaning age, initial test weight and feed efficiency. Estimated genetic progress per generation due to within-line selection was negative in most of the traits in the inbreds but was considerably positive for the linecrosses for most of the traits. As expected, between-line selection yielded greater genetic improvement in the inbred than in the linecross population. The different patterns of response in the two populations are attributed to high rates and levels of inbreeding. Although variable, the actual progress was below prediction in most of the traits studied.     

Estimates of repeatability and heritability of horn fly resistance in beef cattle.

Horn fly population density on 215 beef cows representing seven breed groups and 51 sires was used to obtain estimates of repeatability (rXX) and heritability (h2) for resistance to the horn fly (Haematobia irritans [L.] Diptera: Muscidae). Total horn fly densities were determined weekly on each cow beginning in May and ending in late October or early November of 1988, 1989, and 1990. No insecticides were used on cattle in this study. Estimates of h2 for horn fly resistance (low horn fly number per cow) were obtained by the paternal half-sib method (4 sigma 2S) and as twice the intrasire regression of offspring on dam (2bDD/S). Variance component estimates were obtained using a completely nested ANOVA that included overall mean, breed, sire/breed, cow/sire, and residual error. One hundred twenty-six daughter-dam pairs were available for regression analysis. In a preliminary analysis, the within-breed regression was nonsignificant (P greater than .05), implying that the regression was the same for all breeds; therefore, breed was deleted from the model. The regression model included an overall mean, year, and the intrasire regression of daughter on dam (bDD/S). The estimate of rXX was .47 +/- .02. Estimates of h2 were .78 +/- .16 and .59 +/- .10 from the 4 sigma 2S and 2bDD/S methods, respectively. Similar estimates of rXX and h2 were obtained when each observation of horn fly number per cow (x) was transformed to both log10 (x) and square root of x. These estimates suggest the possibility of selection procedures as an environmentally safe alternative to the use of chemical control.     

Maternal heterosis and grandmaternal effects in beef cattle: postweaning growth and carcass traits

Crossbred steer and heifer progeny from 5-, 6- and 7-yr-old dams produced in a four-breed diallel crossing experiment involving the Brown Swiss, Red Poll, Hereford and Angus maternal grandsires and maternal granddams were evaluated for postweaning growth and carcass traits to estimate breed mean maternal heterosis, maternal heterosis for specific breed cross females, average maternal heterosis for all crosses, breed grandmaternal effects and net breed effects in crosses. All progeny evaluated were born in 1979 and 1980 and were sired by 7/8 or 15/16 Simmental bulls. Average maternal heterosis was significant for 200-d weight in heifers but not in steers and was not significant for final weight (444-d) in either heifers or steers. The effects of maternal heterosis on postweaning growth were not important. Differences among breeds in mean maternal heterosis values were small for growth-related traits. Breeds did not differ (P greater than .05) in grandmaternal effects for growth-related traits; Brown Swiss tended to be highest, Red Poll lowest, with Hereford and Angus intermediate. Differences in net breed effects in crosses favored Brown Swiss over the three other breeds and were generally significant for growth traits. Average maternal heterosis, though generally positive, was not significant for carcass traits on either an age-constant or weight-constant basis. Differences among breeds were small in grandmaternal effects, specific heterosis and net effects in crosses for carcass traits associated with both weight or composition; generally the Brown Swiss breed was favored on carcass traits associated with weight in the age-constant analysis and generally had a higher lean-to-fat ratio than the three other breeds in both the age-constant and weight-constant analyses.     

Genetic and phenotypic relationships of feeding behavior and temperament with performance, feed efficiency, ultrasound, and carcass merit of beef cattle

Feeding behavior and temperament may be useful in genetic evaluations either as indicator traits for other economically relevant traits or because the behavior traits may have a direct economic value. We determined the variation in feeding behavior and temperament of beef cattle sired by Angus, Charolais, or Hybrid bulls and evaluated their associations with performance, efficiency, and carcass merit. The behavior traits were daily feeding duration, feeding head down (HD) time, feeding frequency (FF), and flight speed (FS, as a measure of temperament). A pedigree file of 813 animals forming 28 paternal half-sib families with about 20 progeny per sire was used. Performance, feeding behavior, and efficiency records were available on 464 animals of which 381 and 302 had records on carcass merit and flight speed, respectively. Large SE reflect the number of animals used. Direct heritability estimates were 0.28 +/- 0.12 for feeding duration, 0.33 +/- 0.12 for HD, 0.38 +/- 0.13 for FF, and 0.49 +/- 0.18 for FS. Feeding duration had a weak positive genetic (r(g)) correlation with HD (r(g) = 0.25 +/- 0.32) and FS (r(g) = 0.42 +/- 0.26) but a moderate negative genetic correlation with FF (r(g) = -0.40 +/- 0.30). Feeding duration had positive phenotypic (r(p)) and genetic correlations with DMI (r(p) = 0.27; r(g) = 0.56 +/- 0.20) and residual feed intake (RFI; r(p) = 0.49; r(g) = 0.57 +/- 0.28) but was unrelated phenotypically with feed conversion ratio [FCR; which is the reciprocal of the efficiency of growth (G:F)]. Feeding duration was negatively correlated with FCR (r(g) = -0.25 +/- 0.29). Feeding frequency had a moderate to high negative genetic correlation with DMI (r(g) = -0.74 +/- 0.15), FCR (r(g) = -0.52 +/- 0.21), and RFI (r(g) = -0.77 +/- 0.21). Flight speed was negatively correlated phenotypically with DMI (r(p) = -0.35) but was unrelated phenotypically with FCR or RFI. On the other hand, FS had a weak negative genetic correlation with DMI (r(g) = -0.11 +/- 0.26), a moderate genetic correlation with FCR (r(g) = 0.40 +/- 0.26), and a negative genetic correlation with RFI (r(g) = -0.59 +/- 0.45). The results indicate that behavior traits may contribute to the variation in the efficiency of growth of beef cattle, and there are potential correlated responses to selection to improve efficiency. Feeding behavior and temperament may need to be included in the definition of beef cattle breeding goals, and approaches such as the culling of unmanageable cattle and the introduction of correct handling facilities or early life provision of appropriate experiences to improve handling will be useful.     

Divergent selection for uterine capacity in rabbits. I. Genetic parameters and response to selection

A 10-generation divergent selection experiment for uterine capacity (UC) measured as litter size in unilaterally ovariectomized females was carried out in rabbits. A total of 2,996 observations on uterine capacity of does (up to four parities) was recorded. Laparoscopy was performed at d 12 of their second gestation, and ovulation rate (OR) and number of implanted embryos (IE) were recorded in 735 does. Prenatal survival (PS) was assessed as UC/OR, embryo survival (ES) as IE/OR, and fetal survival (FS) as UC/IE. Genetic parameters and genetic trends were inferred using Bayesian methods. Marginal posterior distributions of all unknowns were estimated by Gibbs sampling. Heritabilities of UC, OR, IE, ES, FS, and PS were 0.11, 0.32, 0.22, 0.04, 0.14, and 0.09, respectively. Genetic and phenotypic correlations between FS and ES were low, suggesting different biological mechanisms for the two periods of survival. After 10 generations of selection, the divergence was approximately 1.5 rabbits, or approximately 1% per generation. Approximately one-half of this response was obtained in the first two generations of selection, which may suggest the presence of a major gene segregating in the base population.     

Fine mapping quantitative trait loci for feed intake and feed efficiency in beef cattle

Feed intake and feed efficiency are economically important traits in beef cattle because feed is the greatest variable cost in production. Feed efficiency can be measured as feed conversion ratio (FCR, intake per unit gain) or residual feed intake (RFI, measured as DMI corrected for BW and growth rate, and sometimes a measure of body composition, usually carcass fatness, RFI(bf)). The goal of this study was to fine map QTL for these traits in beef cattle using 2,194 markers on 24 autosomes. The animals used were from 20 half-sib families originating from Angus, Charolais, and University of Alberta Hybrid bulls. A mixed model with random sire and fixed QTL effect nested within sire was used to test each location (cM) along the chromosomes. Threshold levels were determined at the chromosome and genome levels using 20,000 permutations. In total, 4 QTL exceeded the genome-wise threshold of P < 0.001, 3 exceeded at P < 0.01, 17 at P < 0.05, and 30 achieved significance at the chromosome-wise threshold level (at least P < 0.05). No QTL were detected on BTA 8, 16, and 27 above the 5% chromosome-wise significance threshold for any of the traits. Nineteen chromosomes contained RFI QTL significant at the chromosome-wise level. The RFI(bf) QTL results were generally similar to those of RFI, the positions being similar, but occasionally differing in the level of significance. Compared with RFI, fewer QTL were detected for both FCR and DMI, 12 and 4 QTL, respectively, at the genome-wise thresholds. Some chromosomes contained FCR QTL, but not RFI QTL, but all DMI QTL were on chromosomes where RFI QTL were detected. The most significant QTL for RFI was located on BTA 3 at 82 cM (P = 7.60 x 10(-5)), for FCR on BTA 24 at 59 cM (P = 0.0002), and for DMI on BTA 7 at 54 cM (P = 1.38 x 10(-5)). The RFI QTL that showed the most consistent results with previous RFI QTL mapping studies were on BTA 1, 7, 18, and 19. The identification of these QTL provides a starting point to identify genes affecting feed intake and efficiency for use in marker-assisted selection and management.     

Selection for weaning weight and postweaning gain in Hereford cattle. I. Population structure and selection applied

Single trait selection was practiced in three lines of Hereford cattle derived from a common base population. Selection was practiced on males only within sire families for increased weaning weight (WW) in the WW line (WWL), for postweaning gain (PG) in the PG line (PGL) and at random in the control line (CTL). Females were culled on the basis of age or reproductive failure. Progeny of selected bulls were produced in two herds from 1970 through 1981. The data consisted of records on 2,467 progeny of 125 sires and 922 dams. Generations of selection to produce the 1981 calf crop were 1.96, 1.85 and 1.80 for WWL, PGL and CTL, respectively. For calves born in 1981, mean cumulative selection differentials (CSD) were 54.5 kg in WWL and 37.8 kg in PGL. Corresponding values in standard deviation units (SDU) were 2.31 and 1.68, respectively. Secondary selection differentials were 25 to 40% as large as selection differentials for the primary traits. Unintentional selection in the CTL in 1981 was 16.2 kg or .68 SDU for WW and .2 kg or .01 SDU for PG, respectively. Regressions of CSD on year were 4.1 kg or .17 SDU in WWL and 3.2 kg or .14 SDU in PGL. Realized selection differentials were approximately 88% of the potential selection differentials in both lines. Inbreeding coefficients of dam and calves in 1981 were 2.0 and 3.5% in WWL, 2.1 and 3.5% in PGL and 2.9 and 5.8% in CTL.