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Maged El-Ashker Sabry El-Khodery Nadia Metwally Hussein Hussein Mohamed El-Boshy 《Journal of Equine Veterinary Science》2012
The present study was carried out to assess the prognostic significance of oxidative stress markers in draft horses with colitis associated with phenylbutazone administration under field condition. For this purpose, a total of 40 native breed draft horses were studied. Based on case history, physical examination, and postmortem findings, diagnosis was made. According to the clinical outcome, horses were categorized into survivors and nonsurvivors. Clinically, there was significant association between nonsurvivors and anorexia (P < .01), stasis of intestinal motility (P < .01), melena (P < .01), and diarrhea (P < .001). Biochemically, malondialdehyde and nitric oxide showed a significant increase (P < .05) in nonsurvivors compared with survivors, whereas activities of superoxide dismutase showed a significant decrease (P < .05). Analysis of receiver operating characteristic curve indicated a high sensitivity and specificity of malondialdehyde, nitric oxide, and superoxide dismutase levels (P < .001) to predict the clinical outcome of colitis. Additionally, total protein and albumin showed a significant decrease in nonsurvivors compared with survivors; however, aspartate aminotransferase, sorbitol dehydrogenase, urea, and creatinine showed an increase (P < .05). The present results suggest that estimation of oxidative stress markers and antioxidant parameters may be useful predictors of the clinical outcomes of colitis associated with phenylbutazone administration in draft horses. 相似文献
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Urinary Neutrophil Gelatinase‐associated Lipocalin as a Marker for Identification of Acute Kidney Injury and Recovery in Dogs with Gentamicin‐induced Nephrotoxicity 下载免费PDF全文
C.A. Palm G. Segev L.D. Cowgill B.E. LeRoy K.L. Kowalkowski K. Kanakubo J.L. Westropp 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(1):200-205
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Glomerular Filtration Rate,Urine Production,and Fractional Clearance of Electrolytes in Acute Kidney Injury in Dogs and Their Association with Survival 下载免费PDF全文
T. Francey P. Kass L.D. Cowgill 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2015,29(1):28-34
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Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism 下载免费PDF全文
M.E. Peterson F.V. Varela M. Rishniw D.J. Polzin 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(1):295-304
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Evaluation of Canine Pancreas‐Specific Lipase Activity,Lipase Activity,and Trypsin‐Like Immunoreactivity in an Experimental Model of Acute Kidney Injury in Dogs 下载免费PDF全文
S.E. Hulsebosch C.A. Palm G. Segev L.D. Cowgill P.H. Kass S.L. Marks 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(1):192-199