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为了分析微电流(20微安)对骨折山羊血液中钙磷代谢的影响,探讨微电流促进动物骨折愈合的可能机制,将20只健康山羊随机分为试验组(骨折处通入20微安电流)和对照组,人工造成非开放性全骨折,于骨折前后7次测定血钙和血磷。结果,两组山羊在骨折后均呈现血钙下降、血磷上开放性全骨折,于骨折前后7次测定血钙和血磷。结果,两组山羊在骨折后均呈现血钙下降、血磷上升的趋势(P<0.01)。推断骨折后20d,两组之间血磷差异显著(P<0.05)。微电流能够影响山羊钙磷代谢。 相似文献
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微电流对山羊骨痂钙含量与骨折愈合的作用 总被引:2,自引:0,他引:2
对试验组山羊人工制造非开放性全骨折后,用自制治疗仪以20μA电流治疗,至骨折愈合后取愈合处骨痂,测定骨痂钙含量。结果:试验组山羊骨痂钙含量明显高于对照组山羊,前者比后者骨折愈合时间提前12d,即骨钙含量与骨愈合时间呈明显正相关。用偏振原子分光光度计法(AAS)测析骨折山羊骨痂钙含量显示,微电流能明显提高山羊骨痂钙含量加快骨折愈合,证明骨痂钙含量与骨折愈合呈明显正相关,提示,用20μA电流及其在骨折处形成的微电场,能提高钙离子浓度,并在其他微量元素配合下,通过一系列生化反应,刺激成骨细胞等产生多种生长因子,加快骨细胞增殖进程,缩短山羊骨折愈合时间。 相似文献
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充足和均衡的钙和磷供应对犬的骨骼健康很重要,无论是在生长期,还是成年期。随机选取10只犬,分别补饲市面上2款不同钙片(A、B),探讨补饲钙片2 h前后血清钙、磷的变化。结果表明,A钙片在补饲前后犬血钙浓度升高幅度不大,差异不显著(P>0.05),B钙片在补饲前后犬血钙浓度有所升高,差异显著(P<0.05)。A、B钙片饲喂前后,血磷均相应升高,差异显著(P<0.05),但血钙、血磷仍在正常参考范围内。 相似文献
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试验旨在研究低饲粮阴阳离子差(DCAD,mmol/kg DM)对经乙二胺四乙酸(EDTA)诱导的低血钙山羊的钙调因子水平及瘤胃发酵的影响。选择6只年龄、体重差异不显著的健康母羊,将其随机分为两组(对照组、处理组),每组3个重复,每个重复1只羊。饲粮处理分为两个阶段:(1)在基础饲粮中添加2%EDTA引起低血钙;(2)在此情况下,对照组饲喂高DCAD饲粮(DCAD=203 mmol/kg DM),处理组饲喂低DCAD饲粮(DCAD=-170 mmol/kg DM),其中处理组饲粮为在对照组基础上添加45 g/d的阴离子盐(MgSO4·7H2O+MgCl2·6H2O)。结果表明:(1)两组试验羊干物质采食量(DMI)差异不显著(P>0.05)。处理组尿液pH显著低于对照组(P<0.05)。(2)处理组血浆Ca2+水平显著高于对照组(P<0.05)。与对照组相比,处理组血浆维生素D受体(VDR)、瞬时受体电位通道香草酸受体6(TRPV6)和细胞膜钙泵(PMCA1b)水平显著升高(P<0.05)。但血浆钠... 相似文献
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日粮不同磷水平和钙磷比例对香猪钙磷代谢的影响 总被引:4,自引:0,他引:4
36 头香猪生长阶段去势公猪,通过3 ×3 交叉分组设计,随机分配到9 个处理中,每个处理4个重复,每个重复1 头猪。试验两个因子中日粮磷3 个水平分别为0 .3 % 、0 .6 % 和0 .9 % ,日粮钙磷比的3 个水平为1 1 、1 .25 1 和1 .5 1 。试验基础日粮由玉米、豆粕、血粉和苜蓿粉组成,各处理日粮磷水平和钙磷比用分析纯CaCO3 、Na2HPO4 和CaHPO4 调配。两期钙磷代谢试验结果表明,提高日粮磷水平线性增加香猪钙磷采食量、粪钙磷和尿磷(P< 0 .01) ,0 .6 % 的日粮磷水平在两期试验中表现出最高的磷存留量和磷表观利用率。随日粮钙磷比增加,钙的采食量、粪钙磷和尿钙逐渐增加(P< 0 .01) ,而尿磷逐渐减少(P< 0 .01) 。在体重7kg 时,当钙磷比为1 .25 1 时,钙的表观消化率和表观利用率显著高于1 1组(P< 0 .05) 。在体重17kg 时,钙磷的存留量、钙的表观利用率和磷的表观消化率在日粮钙磷比1 1 时表现最大值(P< 0 .01) ,并且日粮磷和钙磷比互作效应显著影响粪钙磷、尿磷、钙磷存留量、磷的表观消化率和钙磷表观利用率(P< 0 .01) 相似文献
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维生素A、D对肉鸡钙、磷代谢的影响 总被引:8,自引:0,他引:8
本试验旨在研究维生素A、D对肉鸡钙、磷代谢的影响。采用4×4完全随机试验设计,将384只8日龄健康艾维茵雄性肉鸡称重后随机分为16个处理组,每个处理组设3个重复,每个重复8只。其中,VA设4个添加水平,分别为1500、3000、15000和45000IU/kg日粮;VD设4个添加水平,分别为500、1250、2500和5000IU/kg日粮,共构成16个处理组的试验日粮。结果表明:日粮VA水平对肉鸡钙、磷代谢有显著的影响,日粮VA为45000IU/kg时,肉鸡胫骨灰分含量、胫骨矿化度及血清AKP活性相对于1500、3000IU/kgVA组显著下降(P<0.01或P<0.05),胫骨磷含量显著增加(P<0.05),胫骨钙含量趋于增加(P>0.05);日粮VA水平为15000IU/kg时,胫骨钙含量、血清AKP活性有降低的趋势,胫骨磷含量趋升高。日粮VD水平在500~5000IU/kg范围内,对肉鸡的胫骨灰分含量、胫骨钙、磷含量、胫骨矿化度及血清AKP活性无显著影响(P>0.05),但随着VD添加剂量的增加,血清钙、磷含量呈一次线性增加,胫骨钙含量呈二次曲线上升趋势。日粮VA为15000IU/kg时,肉鸡VA临界过量;日粮VA为45000IU/kg时,肉鸡VA过量。日粮VD水平在500~5000IU/kg范围内,对肉鸡的钙、磷代谢无显著影响。 相似文献
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Vitti DM Kebreab E Lopes JB Abdalla AL De Carvalho FF De Resende KT Crompton LA France J 《Journal of animal science》2000,78(10):2706-2712
The effect of increasing phosphorus (P) intake on P utilization was investigated in balance experiments using 12 Saanen goats, 4 to 5 mo of age and weighing 20 to 30 kg. The goats were given similar diets with various concentrations of P, and 32P was injected to trace the movement of P in the body. A P metabolism model with four pools was developed to compute P exchanges in the system. The results showed that P absorption, bone resorption, and excretion of urinary P and endogenous and fecal P all play a part in the homeostatic control of P. Endogenous fecal output was positively correlated to P intake (P < .01). Bone resorption of P was not influenced by intake of P, and P recycling from tissues to the blood pool was lesser for low P intake. Endogenous P loss occurred even in animals fed an inadequate P diet, resulting in a negative P balance. The extrapolated minimum endogenous loss in feces was .067 g of P/d. The minimum P intake for maintenance in Saanen goats was calculated to be .61 g of P/d or .055 g of P/(kg(.75) x d) at 25 kg BW. Model outputs indicate greater P flow from the blood pool to the gut and vice versa as P intake increased. Intake of P did not significantly affect P flow from bone and soft tissue to blood. The kinetic model and regressions could be used to estimate P requirement and the fate of P in goats and could also be extrapolated to both sheep and cattle. 相似文献
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1996年以来,本检测中心共检测了十几个县市送检的53个钙磷类饲料样品,对其质量评定及杂质鉴别方法进行了试验,并对劣质原料对家禽的危害进行了调查研究,现报告如下:1钙磷类饲料的检验1.1送检样品 1996年~1999年共收到烟台、威海、青岛和潍坊等地。市送检骨粉21份、磷酸氢钙32份。1.2常规检验 钙磷类饲料中钙的测定采用高锰酸钾还原滴定法,磷的测定采用钼黄比色法,氟的测定采用氟离子选择电极法。 合格骨粉和磷酸氢钙的标准:骨粉,P>11.0%,Ca>24%;磷酸氢钙,P>16.0%,Ca>21. … 相似文献
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Thilsing T Larsen T Jørgensen RJ Houe H 《Journal of veterinary medicine. A, Physiology, pathology, clinical medicine》2007,54(2):82-91
Previous studies have proved the possibility of preventing parturient hypocalcaemia by zeolite A supplementation during the dry period, and a recent in vitro study has indicated a marked calcium (Ca) as well as phosphorus (P) binding effect of zeolite A in rumen fluid solutions. Because of the connection between the Ca and P homeostatic systems, the preventive effect against parturient hypocalcaemia may arise from zeolite induced decreased availability of dietary Ca as well as P. In the present study, the expected Ca and P binding capacity was challenged by feeding high and low levels of dietary Ca and/or P to zeolite A treated dry cows. Twenty-one pregnant dry cows were assigned to four experimental groups receiving a dry cow ration unsupplemented or supplemented with extra Ca and/or P. During the last 2 weeks of the dry period all cows additionally received 600 g of zeolite A per day. A high level of dietary P prepartum significantly decreased the plasma Ca concentration before as well as immediately after calving (day 0-3). Conversely, the plasma inorganic phosphate concentration was higher among these cows than among cows receiving no supplemental P. The prepartum dietary Ca level significantly affected the serum 1,25-dihydroxyvitamin D concentration during zeolite supplementation, whereas the periparturient plasma Ca concentration was apparently not affected by the dietary Ca level. During zeolite A supplementation plasma parathyroid hormone was significantly higher among cows receiving additional P. The urinary deoxypyridinoline/creatinine ratio was not affected by the prepartal dietary Ca or P level. Serum aluminium (Al) was significantly higher during zeolite A supplementation than during the preceding period, indicating partial destruction of the zeolite in the intestinal tract with subsequent release and absorption of Al. It is suggested that the effect of prepartum zeolite supplementation on the periparturient Ca homeostasis depends on the level of Ca as well as P in the dry cow ration. 相似文献
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J. F. M. NOUWS B. P. W. MEESEN H. VAN GOGH C. KORSTANJE A. S.J. P. A. M. VAN MIERT T. B. VREE† M. DEGEN 《Journal of veterinary pharmacology and therapeutics》1988,11(2):145-154
After testosterone pretreatment of castrated goats and during the rutting season of adult entire male goats, the oxidative metabolism of sulphadimidine (SDM) was inhibited markedly compared with the castrated control state of these animals. The oxidation of the 5 position (yielding 5-hydroxysulphadimidine) and of the 6-hydroxymethyl group (yielding 6-carboxysulphadimidine) was decreased equally, with that of the methyl group at the pyrimidine side chain itself being 6-hydroxymethylsulphadimidine (CH2OH), whereas the acetylation pathway was unaffected by testosterone. The consequence of altered metabolism by testosterone was a prolongation of SDM presence in the body. Effects on protein binding of the CH2OH metabolite and on the renal clearance of SDM were also investigated. 相似文献
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V.B. Meacham BS 《Journal of Equine Veterinary Science》1984,4(5):210-214
Mineral metabolism in the equine is a complex process involving absorption sites and interactions between the minerals themselves and other compounds. Factors such as the digestibility of the minerals and the extent of the interactions all play an important role in the mineral amounts required in the diet.Inadequate levels of minerals in the diet can lead to physiological maladies such as HNS and Ricketts. A knowledge and understanding of mineral metabolism is essential to the success of equine management. 相似文献