Panosteitis in dogs

The clinical and radiographic signs of panosteitis in seven dogs are described and also the histological and fluorochrome-labelled appearance of the lesions in one of them. The condition was seen in three immature German Shepherd dogs, three immature mongrels, of which two were littermates, and an adult Doberman Pinscher which presented with lesions of its metacarpus.     

Ketamine in dogs

The cardiopulmonary consequences of ketamine (10 mg/kg, IV) were evaluated in 18 dogs. Heart rate, cardiac output, systemic blood pressure, left ventricular work, oxygen transport, oxygen consumption, carbon dioxide production, and core temperature increased. Breathing rate, minute ventilation, and arterial partial pressure of oxygen transiently decreased. Arterial partial pressure of carbon dioxide, alveolar-arterial oxygen gradient, and venous admixture transiently increased. The duration of action of ketamine for surgical anesthesia was short. Muscle tone and salivation were excessive, and spontaneous muscular activity was prominent.     

犬木糖醇中毒的研究进展

木糖醇是一种天然的五碳糖醇,在自然界中分布范围广,在各种水果和蔬菜等中存在,常作为甜味剂用于无糖的糖果和口香糖、甜点、饮料和牙膏等中。木糖醇虽对绝大部分哺乳动物安全性高,但对犬类却具有致命的毒性作用。犬摄入超过0.1 g/kg的木糖醇会有低血糖的风险,摄入超过0.5 g/kg可能产生肝毒性,会危及生命且木糖醇中毒无特效解毒剂。由于人类消费木糖醇各种产品的扩大以及宠物产业的发展,使得犬类接触木糖醇并引起中毒的几率大大增加。本研究主要从犬木糖醇中毒的毒代动力学、临床症状与病理变化及救治和检测等方面予以综述,以期引起重视并为中毒的预防和救治提供参考。     

Neosporosis in dogs

A bitch was inoculated subcutaneously and intramuscularly with Neospora caninum tachyzoites on Day 35 of pregnancy. Eight pups were born 28 days later. Five pups became ill and necropsies were performed before 20 days of age. Three pups and the bitch remained clinically normal for 7 weeks after parturition when they were intramuscularly injected with 40 mg kg-1 methylprednisolone acetate weekly to activate chronic N. caninum infection. Necropsies were performed 48, 17, 18, and 18 days respectively after administration of corticosteroids. Hepatic necrosis, pneumonia, encephalomyelitis, and myonecrosis were the main changes seen in these dogs.