犬群发生钩端螺旋体病的诊疗体会

华南某犬场爆发以腹胀、皮肤粘膜黄染、血尿、后肢麻痹瘫痪等多种临床病症为特征的传染病,全场有犬82头,发病死亡8头,死亡率9．7％,发生后肢麻痹瘫痪5头占6％。根据流行病学、临床症状、解剖变化、实验室检查,证实该犬群感染了钩端螺旋体病菌并发生了钩体病,现将诊断和治疗结果报告如下：     

犬钩端螺旋体病的诊疗体会

犬钩端螺旋体病一般是由犬钩体和出血性黄疸钩体引起的,2种钩体引起2种不同的病型:即出血性黄疸型和伤寒型,但在临床上不易区分开来。感染此病的大部分犬仅表现亚临床感染或取慢性经过,症状亦不明显,但如果有使机体抵抗力降低的因素出现,则引起急性发病,且病死率高。现将这几年在门诊接诊的十几例犬钩体病诊治体会介绍如下。1临床症状发病突然,以高热(39·5~41℃)开始,食欲下降至绝食,有饮欲。第2天体温可降至常温或常温以下,但食欲不能恢复。病犬呕吐初为消化液,后为胆汁或咖啡色液体。第3~4天病犬眼结膜、口腔黏膜呈现黄疸,继之全身皮肤黏…     

犬钩端螺旋体病的诊疗

钩端螺旋体病（简称钩体病）是由致病性钩端螺旋体引起的一种重要的人犬共患传染病。该病原菌菌型复杂,目前共有23个血清群,每个血清群内又可分为若干个血清型。由于致病性钩端螺旋体有着广泛的动物宿主,临床症状多样,很多动物呈隐性感染,在犬群中的感染率也比较高,对犬的健康和公共卫生构成了较大危害。     

犬钩端螺旋体病的诊疗

钩端螺旋体病是一种人畜共患传染病,由犬钩端螺旋体或出血性黄疸钩端螺旋体引起。所有年龄的犬都易感,公犬和幼犬的发病率较高。近年来,该病在本地区频频出现,笔者曾诊治7例出血性黄疸型犬钩端螺旋体病,治愈3例,4例因就诊时病情严重,未能治愈。现将诊治情况报道如下。     

犬钩端螺旋体病的综合治疗

犬钩端螺旋体病又称犬伤寒 ,是由致病性钩端螺旋体所致的一种人畜共患传染病 ,临床上以肾炎、黄疸为特征。该病雄犬发病率高于雌犬 ,幼犬发病率高于老年犬。近年来 ,该病在本地区呈地方性流行 ,给养犬户带来一定的经济损失。经过摸索 ,笔者采取综合诊疗措施 ,共治疗该病犬 1 32只 ,治愈 1 1 5只 ,死亡 1 7只 ,治愈率为 87.1 2 %。在死亡的 1 7只病犬中多因发病后未及时治疗所致。1　症状1 .1　患出血性黄疸型钩端螺旋体病。自然感染的潜伏期为 5～ 1 5天。发病突然 ,精神沉郁 ,食欲废绝 ,体温升高 ,呕吐 ,肌肉震颤 ,四肢无力 ,不能站立 ,眼…     

犬钩端螺旋体病的综合治疗

犬钩端螺旋体病是由致病性钩端螺旋体所致的一种临床上以肾炎 ,出血黄疸为特征的人畜共患传染病。本病雄犬发病率高于雌犬 ,幼犬发病率高于老年犬。近两年来 ,在呈贡县呈地方性流行 ,给养犬户带来一定的经济损失。经过采取综合诊疗防制措施 ,使该病得到有效控制。1　主要症状及病理变化自然感染的潜伏期为 5～ 15d。出血黄疸型钩端螺旋体病 ,发病突然 ,体温升高 ,呕吐 ,震颤 ,食欲废绝 ,精神沉郁 ,四肢无力不能站立 ,眼结膜极度充血 ,尿呈豆油色 ,粘膜黄染 ,当发生黄疸后不久死亡。犬型钩端螺旋体病犬无黄疸现象 ,病程较缓。体温可升至39 5…     

犬钩端螺旋体病的诊疗体会

<正>犬钩端螺旋体病是1种重要的人畜共患病,常表现为黄疸型和伤寒型两种显性感染,临床症状以出血型和黄疸型为主。由于该病对公共卫生影响较大,因此该病的诊疗工作有其特殊意义。笔者从     

犬钩端螺旋体病的诊治

1 基本情况 我旗镇区周某于2003年3月始建特种经济动物饲养场，本地犬32条，其中公犬3条，母犬29条。于2004年4月从外地引进肉型种公犬3条(2～3岁龄)，总共35条。3天后引进的3条犬开始发病，经过会诊治疗，于5天后基本控制疫情，报告如下。     

猪钩端螺旋体病的诊治

2003年12月中旬，延寿市某养猪户喂养的21头3月龄猪突然发病。病猪突然发烧，食欲下降或废绝，尿色血红，发病猪5头，死亡1头。现报道如下。     

Three cases of canine leptospirosis in Quebec

Three dogs from different locations with acute renal failure were hospitalized in autumn 1996 and 1997. Leptospira interrogans serovar pomona was detected by the microscopic agglutination test. All dogs recovered after antibiotic treatment. The importance of the development of vaccines adapted to emerging serovars in dogs should be addressed.     

Clinical and epidemiological features of canine leptospirosis in North Queensland

OBJECTIVE: To evaluate the clinical signs, results of clinical pathology and serology tests, and treatment outcome of clinical leptospirosis in 40 dogs from North Queensland. DESIGN: Retrospective study from January 1995 to August 1999. PROCEDURE: Case records were reviewed for age, breed, sex, month of submission, geographical location and presenting clinical signs in 40 dogs with titres of > or = 200 for leptospirosis by the microscopic agglutination test. A biochemistry panel and complete blood count were performed on 18 dogs. RESULTS: Canine leptospirosis occurred most frequently during the summer and autumn particularly in the 'wet' tropical coastal areas of Mackay and Cairns. Fewer cases were seen in the Atherton Tablelands and 'dry' tropics around Townsville. Young and male dogs were more commonly affected. Most cases were caused by L australis (80%) and L zanoni (15%) with individual cases of L hardjo and L copenhageni. All dogs showed a distinctive multiorgan disease pattern including renal failure and cholestatic hepatopathy. Presenting clinical signs were related to these disease syndromes and included jaundice, vomiting, lethargy, inappetence, dehydration, pyrexia, abdominal pain and diarrhoea. Just over 50% of the dogs in the present study failed to recover. Clinical biochemical changes indicative of renal failure and cholestasis were significantly less severe in dogs that recovered compared with dogs that did not survive. CONCLUSIONS: Clinical pathology testing should be performed on all dogs presented for illness in the endemic areas so as to help make a presumptive diagnosis and assist in determining the prognosis as soon as possible. The presumptive diagnosis should be confirmed serologically.     

Serodiagnosis of canine leptospirosis by solid-phase enzyme-linked immunosorbent assay

An enzyme-linked immunosorbent assay (ELISA) to detect antibodies to Leptospira interrogans serotype canicola in dogs was developed and evaluated. Comparison of the ELISA with the microscopic agglutination test (MAT) showed that, during the first two weeks after an experimental infection with serotype canicola, the ELISA detected antibody at higher dilutions than the MAT. After the second week post-infection both tests detected antibody at almost equal titres (r = 0.89). The outer envelope (OE) antigen of serotypes icterohaemorrhagiae, copenhageni and canicola was fairly serotype-specific, whereas the pellet (P) antigen showed more cross-reactivity. Both OE and P antigen of Leptospira biflexa strain Patoc I could be used as cross-reacting antigen in the ELISA. Compared to the MAT, the ELISA has some technical advantages. It is suggested that the ELISA would be useful as a screening test.     

Recombinant LipL32 antigen-based single serum dilution ELISA for detection of canine leptospirosis

A recombinant antigen-based single serum dilution enzyme-linked immunosorbent assay (ELISA) was developed to measure the specific antibody activity in sera of dogs with leptospirosis. The recombinant antigen developed and used in the assay was specific for the pathogenic serovars of Leptospira. A linear relationship was found to exist between the predicted antibody titres at a single working dilution of 1:1000 and the corresponding observed serum titres as determined by the standard serial-dilution method. Regression analysis was used to determine a standard curve from which an equation can be derived that allows demonstration of the mentioned correlation. The equation was then used to convert the corrected absorbance readings of the single working dilution directly into the predicted ELISA antibody titres. The assay was proved to be sensitive, specific and accurate as compared to the standard microscopic agglutination test (MAT).