No significant changes were noted in Na and Ca concentration in either serum or uterine fluid. On the other hand, significant changes in the Mg, K and P were observed. Both drugs have caused a decrease in the content of Mg in the serum (P<0.05) during diestrus, a fall in the level of uterine K (P<0.01) during proestrus and a decrease of P during proestrus both in serum (P<0.001 after dexamethasone treatment) and in uterine fluid (P<0.001 for both drugs).
It is obvious that the two drugs change the chemical composition of blood and endometrial secretions. This could jeopardize the survival of the spermatozoids and of the ovum as well as the fertilization and the implantation processes.
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In the sera of the infected animals the hemagglutinating antibodies were present at low titers at the third week post-infestation by using somatic extract of G. intestinalis and at the seventh week in case of G. nasalis. At eight weeks post-infestation the antibody titers reached their maximum 1:8192 (G. intestinalis) and 1:4096 (G. nasalis), then dropped at 12 weeks post-infestation.
The complement fixing antibodies were present occasionally between the seventh and 11th weeks after infestation. Precipitating antibodies were absent in all sera.
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