The effect of lean growth rate on puberty attainment in gilts

Two hundred sixteen prepubertal Genex Manor hybrid F1 gilts were used to determine the impact of lean growth rate on sexual development of gilts. This study was composed of two experiments (Exp. 1 and Exp. 2). In Exp. 1, at approximately 96 d of age and 54 kg weight, gilts were allocated with respect to growth rate and litter origin to one of two dietary treatments: 1) a diet formulated to maximize lean growth potential (LP; n = 84) or 2) a diet formulated to produce a lower lean growth rate (LL; n = 84). In Exp. 2, at approximately 88 d of age and 50 kg weight, gilts were allocated with respect to growth rate and litter origin to one of two dietary treatments: 1) a diet formulated to maximize lean growth potential (LP; n = 24) or 2) a diet formulated to restrict lean growth further than was achieved in LL in Exp. 1 (RL; n = 24). All gilts were fed treatment diets for ad libitum consumption and housed in groups of six. Weight, backfat depth and loin depth, and feed intake were measured weekly. Starting at 135 d of age, gilts received 20 min of direct daily exposure to a boar as a pen group for pubertal stimulation. Puberty attainment was determined as the day gilts first exhibited the standing reflex in response to contact with a boar. At pubertal estrus, body weight, backfat depth, and loin depths were recorded. Diet affected (P < or = 0.05) estimated fat-free lean gain (LP, 424 vs LL, 347 g/d, Exp. 1; LP, 397 vs RL, 376 g/d, Exp. 2) during the growth period (start to stimulation). However, age at puberty was not affected by diet (LP, 157.3 vs LL, 157.6, Exp. 1; LP, 166.7 vs RL, 167.3, Exp. 2) or overall lean growth at stimulation (P > or = 0.05 in both experiments), confirming that innate variability in sexual development of commercial genotypes, rather than growth performance, determines onset of sexual maturity. A negative correlation between age at puberty and growth rate from 50 kg until puberty (P < or = 0.05) (LP, r = -0.40, LL, r = -0.36, Exp. 1; LP, r = -0.64, RL, r = -0.48, Exp. 2) was a consequence of reduced lean tissue growth during the stimulation period in later-maturing gilts.     

Changes to daily feed intake during the laying period alters embryonic MSTN and MYOG gene expression in genetically fat and lean lines of chickens

1. Broiler breeders are unable to self-regulate feed intake to a level that permits reproductive function and restricted feeding is normal for broiler parent stock. The aim of this study was to determine whether myostatin (MSTN) and myogenin (MYOG) mRNA expression could be altered in relation to differences in body composition of the embryos and the hen’s diet.

2. A 2 × 2 factorial experiment was conducted with two dietary intake levels (100% and 75% of nutrition recommendation) and two broiler genotypes (Fat line and Lean line). Hens (384 of each line) were randomly divided at 23 weeks of age into 4 treatments, with each treatment represented by 12 replicates of 16 birds each. The experiment started when the rate of lay reached 5% and continued until 54 weeks of age.

3. There were significant effects of line and dietary intake, and interactions between them on MSTN and MYOG mRNA expression levels in embryonic tissues. The trend in MSTN mRNA expression level over the embryonic period was similar between lines. Low daily feed intake did not alter the trend in MSTN mRNA expression levels in either line, but significantly changed the peak values. MYOG mRNA expression varied by line and over time, with a delay in the Lean line. Low daily feed intake influenced the trend in MYOG mRNA expression levels in both lines and delayed its onset.     

Effect of daily feed intake in laying period on laying performance, egg quality and egg composition of genetically fat and lean lines of chickens

1. The objectives of this study were to evaluate the effects of feed intake on laying performance, egg quality and egg composition in a Fat line and a Lean line during the laying period (34 to 54 weeks of age). 2. The experiment was a 2 × 2 factorial design with two dietary intake levels (nutrition recommendation and 75% of recommendation) and two broiler genotypes (Fat line and Lean line). Hens (384 of each line) were randomly divided at 23 weeks of age into 4 treatments, with each treatment represented by 12 replicates of 16 birds each. The experiment started when the rate of lay reached 5% and continued until 54 weeks of age. 3. The results indicated that there was a significant interaction between daily feed intake and genotype on egg production, egg weight, percentage yolk, yolk/albumen ratio and yolk cholesterol content. Fat line hens produced significantly more eggs and had a lower incidence of cracked eggs than the Lean line hens. The reduction in feed intake decreased egg weight and increased egg production, egg-shape index and cholesterol content of yolk significantly.     

Effects of oestradiol benzoate injections, exposure to the boar and age on the attainment of puberty in the gilt

Thirty large white cross Landrace prepubertal gilts from five litters were allocated at random within litters to one of six treatment. All the gilts were given three daily intramuscular injections of 6 micrograms/kg liveweight of oestradiol benzoate but the first injection was given at either 100 days, 120 days, 140 days, 160 days, 180 days or 200 days old. From the time the first oestrogen injection was given, until the end of the experiment, the gilts were allowed daily contact with a boar for 20 minutes. The gilts were mated with a mature boar at the appearance of the second oestrus and they were slaughtered 20 days later. The numbers of gilts ovulating in the treatment groups were determined from plasma progesterone concentrations measured twice weekly throughout the experiment. The numbers of gilts ovulating within 10 days of the oestradiol benzoate injections were 3 of 5, 1 of 5, 0, 0, 3 of 5 and 1 of 5, respectively, in the groups first treated at 100 days, 120 days, 140 days, 160 days, 180 days and 200 days old. For those gilts which were successfully mated, no significant differences were observed between the treatment groups in the number of viable embryos per gilt.     

Thyroid activity in relation to feed intake, growth rate and feed conversion in growing heifers

Phenotypic and genetic parameters for thyroid activity (T4 serum level, T4 apparent distribution volume, T4 fractional turnover rate and T4 degradation), and for certain production traits (roughage dry matter intake, daily weight gain and roughage dry matter/kg weight gain), were investigated in cattle. In the experiment, 480 growing heifers were studied, daughters of 20 AI sires previously tested for thyroid activity. Repeatabilities for thyroid traits 2-3 months apart varied, with an average 0.3-0.6 for the different traits. Heritability estimates based on sire components were 0.1-0.4 for the thyroid traits, 0.16 +/- .10 for roughage intake and 0.18 +/- .11 for daily gain. The sire component for feed efficiency (roughage dry matter/kg weight gain) was 0, and genetic correlations between thyroid traits and the production traits in growing heifers were low with large standard errors.     

Correlated responses in sow appetite, residual feed intake, body composition, and reproduction after divergent selection for residual feed intake in the growing pig

Residual feed intake (RFI) has been explored as an alternative selection criterion to feed conversion ratio to capture the fraction of feed intake not explained by expected production and maintenance requirements. Selection experiments have found that low RFI in the growing pig is genetically correlated with reduced fatness and feed intake. Selection for feed conversion ratio also reduces sow appetite and fatness, which, together with increased prolificacy, has been seen as a hindrance for sow lifetime performance. The aims of our study were to derive equations for sow RFI during lactation (SRFI) and to evaluate the effect of selection for RFI during growth on sow traits during lactation. Data were obtained on 2 divergent lines selected for 7 generations for low and high RFI during growth in purebred Large Whites. The RFI was measured on candidates for selection (1,065 pigs), and sow performance data were available for 480 sows having from 1 to 3 parities (1,071 parities). Traits measured were sow daily feed intake (SDFI); sow BW and body composition before farrowing and at weaning (28.4 ± 1.7d); number of piglets born total, born alive, and surviving at weaning; and litter weight, average piglet BW, and within-litter SD of piglet BW at birth, 21 d of age (when creep feeding was available), and weaning. Sow RFI was defined as the difference between observed SDFI and SDFI predicted for sow maintenance and production. Daily production requirements were quantified by litter size and daily litter BW gain as well as daily changes in sow body reserves. The SRFI represented 24% of the phenotypic variability of SDFI. Heritability estimates for RFI and SRFI were both 0.14. The genetic correlation between RFI and SRFI was 0.29 ± 0.23. Genetic correlations of RFI with sow traits were low to moderate, consistent with responses to selection; selection for low RFI during growth reduced SDFI and increased number of piglets and litter growth, but also increased mobilization of body reserves. No effect on rebreeding performance was found. Metabolic changes previously observed during growth in response to selection might explain part of the better efficiency of the low-RFI sows, decreasing basal metabolism and favoring rapid allocation of resources to lactation. We propose to consider SRFI as an alternative to SDFI to select for efficient sows with reduced input demands during lactation.     

Effects of growth hormone-releasing factor and feed intake on energy metabolism in growing beef steers: whole-body energy and nitrogen metabolism.

Effects of growth hormone-releasing factor (GRF) on energy and N metabolism in six growing Hereford x Angus steers were measured using a split-plot design with 4-wk injection periods within 8-wk intake periods. Steers were fed a 75% concentrate pelleted diet at two intakes (low: 50 g/BW.75 and high: 90 g/BW.75 as fed) and injected s.c. with saline or 10 micrograms/kg of BW of human GRF(1-29)NH2 twice daily for 3 wk. Measurements of energy and N balance were obtained during wk 3 of treatments. Diet DM digestibility (%) was decreased by greater intake (P less than .05) and increased by GRF (P less than .06). Treatment with GRF increased (P less than .01) N retention by decreasing (P less than .05) fecal and urinary excretion: N retention averaged 10.0 and 20.8 g/d at low intake and 25.9 and 46.7 g/d at high intake for control- and GRF-treated steers, respectively. Increased ME (P less than .05) in GRF-treated steers also resulted from decreased fecal (P less than .05) and urinary (P less than .07) energy excretion but was countered by increased (P less than .06) heat energy (HE). Tissue energy (TE), partial efficiency of ME use for TE retention, and estimated maintenance energy were not affected (P greater than .10) by GRF treatment. In summary, GRF treatment altered the partition of TE by increasing protein retention (108 and 80% for low and high intake, respectively) at the expense of fat retention.     

Feeding time and feeding rate and its relationship with feed intake, feed efficiency, growth rate, and rate of fat deposition in growing Duroc barrows

Because feed is the major cost to pork production, management practices and breeding strategies are aimed at optimizing feed intake. Knowledge about the shape of feed intake and feeding behavior curves may be of interest for optimization of lean meat production. This study investigated trends based on daily measurements of feeding behavior in 200 Duroc barrows, originating from 5 sires and 200 dams, during growth. Daily values were examined between 88 and 188 d of age. Furthermore, phenotypic correlations between feeding length and feeding rate, and feeding frequency, feed intake, residual feed intake, growth rate, and rate of fat deposition were investigated for a period between 95 and 175 d of age. No differences were observed between sires for parameter estimates of a curvilinear function fitted to data on feeding length as a function of age, but the effect of sire was significant (P < 0.01) for values at individual ages up to 132 d of age. Feeding rate (feed ingested for each minute spent eating) increased in a linear fashion with age (average R(2) = 0.80) and differently so for different sires (P < 0.05 for the intercept and P < 0.01 for the regression coefficient). Because the increase in BW is linear over this time period (average R(2) = 0.99), the results suggest that feeding rate increased with increased BW and is related to the physical capacity for feed intake. Results indicate that pigs that ate faster also ate more (r = 0.29, P < 0.001), grew faster (r = 0.40, P < 0.001), and grew fatter (r = 0.28, P < 0.001), but had no greater or lower residual feed intake (r = -0.01). The linear regression slope of feeding rate on age seemed inherent to the individual and was correlated with feed intake but not with residual feed intake. Feeding length may be selected for in order to regulate absolute feed intake at different stages of growth.     

Effects of exogenous ghrelin on feed intake, weight gain, behavior, and endocrine responses in weanling pigs

The objectives were to determine relative ADG, ADFI, behavior, and endocrine responses in weaned pigs receiving exogenous ghrelin. Twenty-four barrows weaned at 18 d of age (d 0 of the experiment) were catheterized via the jugular vein, weighed, and assigned to either a ghrelin (n = 12) or saline (control; n = 12) infusion group. Initial pig BW did not differ between treatments (7.87+/-0.39 vs. 7.92+/-0.35 kg for ghrelin and control treatments, respectively). Pig BW and feed intakes were measured once daily throughout the experiment. Starting on d 1, the ghrelin pigs were intravenously infused three times daily for 5 d with 2 microg/kg BW of human ghrelin, and the control pigs were similarly infused with saline. Activity observations and blood samples were taken at -15, 0, 15, 30, 60, 90, 120, 240, and 480 min relative to the first infusion and then three times daily (0800, 1600, and 2400) for 8 d. Weight gain during the 5-d infusion period was greater by the ghrelin than by control pigs (0.57+/-0.10 vs. 0.21+/-0.13 kg, respectively; P < 0.04); however, there was no increase in feed intake. During two behavioral observation periods, more pigs in the ghrelin treatment were observed eating compared with control pigs (P < 0.05). The initial infusion of exogenous ghrelin increased serum ghrelin, GH, insulin, and cortisol concentrations (P < 0.05). Endogenous serum ghrelin increased from d 1 to 8 of the experiment in control animals (P < 0.05). Serum IGF-I initially fell in both treatment groups from d 1 to 2 (P < 0.05) but then increased from d 5 to 8 (P < 0.05). Peripheral concentrations of glucose in the ghrelin pigs were greater on d 2, 3, 7, and 8 than on d 1 (P < or = 0.05). In both treatment groups, peripheral concentrations of leptin increased from d 7 to 8, and cortisol decreased from d 1 to 5 of the experiment. These observations provide evidence that ghrelin may positively influence weight gain and concomitantly increase GH, insulin, and cortisol secretion in weaned pigs.     

Renewed selection for heat loss in mice: direct responses and correlated responses in feed intake, body weight, litter size, and conception rate

Divergent selection in mice was renewed in 3 independent replicates for high (MH) and low (ML) heat loss. An unselected control (MC) was maintained in all replicates. Heat loss was measured for individual male mice for 15 h, overnight in direct calorimeters. After 16 initial generations of selection followed by 26 generations of relaxed selection, divergent selection resumed for 9 generations. The realized selection applied was very close to the maximum possible selection according to the criteria and protocol. Selection differentials were greater for high than for low selection due to greater variation in the MH line. When corrected for SD, standardized selection differentials were similar for MH and ML selection. Unintended selection in MC was negligible. Realized heritability for divergence was 0.14 +/- 0.01, which was considerably less than that realized during the initial generations of selection (0.28 +/- 0.03). Realized heritabilities for MH selection (0.16 +/- 0.05) and for ML selection (0.07 +/- 0.06) were less, especially for ML selection, than were observed in the earlier generations. The difference in heat loss between MH and ML males was 55.7% of the MC mean at generation 51, compared with a difference of 53.6% in generation 15; this difference had decreased to 34.4% at the end of the relaxed selection (generation 42). For feed intake between 8 and 11 wk, MH and ML males differed by 34.0% of the MC mean by the end of the selection process. Body weight at 12 wk for MH and ML males was less than for MC males. Litter size response was positively related to the heat loss response. Conception rate was poorer in MH matings than in MC and ML matings.     

Phenotypic and genetic relationships between residual energy intake and growth, feed intake, and carcass traits of young bulls.

Residual energy intake, defined as actual minus predicted energy intake during a production period, was estimated for each of 650 bull calves of 31 Holstein Friesian or Brown Swiss sires. Residual energy intake, measured under ad libitum feeding, had heritabilities similar to those of growth rate and energy conversion ratio with an estimate of approximately .3. Residual energy intake was related to average daily energy intake both phenotypically and genetically such that selection for decreased residual energy intake would lead to a decrease in daily feed intake. Such selection would also tend to increase carcass fatness (i.e., genetically fat animals are the most efficient). Residual energy intake estimated with and without correction for carcass composition were closely correlated. Thus, residual energy intake may be estimated without the knowledge of carcass composition in growing bulls of dual-purpose breeds.     

丝兰提取物对三角鲂摄食、生长、饲料利用及废物排放的影响

在室外养殖桶中进行8周饲养实验以评估丝兰提取物对三角鲂(Megalobrama terminalis)摄食、生长、饲料利用、鱼体组成及废物排放的影响。在三角鲂基础饲料中分别添加0%(Y0)、0.05%(Y1)、0.15%(Y2)、0.25%(Y3)、0.35%(Y4)和0.45%(Y5)的丝兰提取物,每天饱食投喂实验鱼(16.0±0.8)g两次。研究结果显示,随着丝兰提取物添加水平的增加,实验鱼的终末体重、增重率和特定生长率呈先上升后下降趋势。与对照组Y0相比,实验组Y3具有最高的终末体重、增重率、特定生长率、饲料氮储积效率,最低的饲料系数和磷废物排放量(P0.05)。实验组Y2的FI显著高于对照组Y0(P0.05),而各实验组与对照组Y0之间的饲料磷储积效率、肥满度、肝体指数、鱼体组成(水分、粗蛋白质、粗脂肪、灰分、磷和氨基酸)均无显著差异(P0.05)。研究表明,在三角鲂饲料中添加0.25%的丝兰提取物可显著提高三角鲂的生长和饲料利用效率,并降低养殖废物排放。     

Effects of continuous ivermectin treatment from birth to puberty on growth and reproduction in dairy heifers.

The effect of continuous ivermectin treatment from birth to puberty on growth and reproductive performance was studied in Holstein heifer calves grown on pastures in comparison to naturally nematode-infected, untreated animals. Ivermectin effectively abated the presence of nematode eggs in feces. Eggs per gram (EPG) in parasitized animals increased rapidly from wk 12 to 18 of age and then decreased. Animals treated with ivermectin grew faster than untreated ones, and differences in body weight became significant at 6 wk of life, even before eggs appeared in the feces of either treatment group. Ivermectin-treated heifers reached puberty 3 wk earlier than infected ones as assessed with serum progesterone concentrations (ivermectin, 30.4 +/- .8 vs untreated, 33.7 +/- 1.3 wk of age). This delay was not directly related to body weight. In addition, pelvic area at 39 wk and at 15 mo of age was increased in treated heifers (8 and 11%, respectively) compared with parasitized animals. No differences in the wither heights were observed. We conclude that ivermectin treatment in dairy heifers may increase growth rate during development, advance the onset of ovarian function, and positively affect yearling pelvic area.     

Direct responses to selection for increased litter size, decreased age at puberty, or random selection following selection for ovulation rate in swine

Nine generations of selection for high ovulation rate were followed by two generations of random selection and then eight generations of selection for increased litter size at birth, decreased age at puberty, or continued random selection in the high ovulation rate line. A control line was maintained with random selection. Line means were regressed on generation number and on cumulative selection differentials to estimate responses to selection and realized heritabilities. Genetic parameters also were estimated by mixed-model procedures, and genetic trends were estimated with an animal model. Response to selection for ovulation rate was about 3.7 eggs. Response in litter size to selection for ovulation rate was .089 +/- .058 pigs per generation. Average differences between the high ovulation rate and control lines over generations 10 to 20 were 2.86 corpora lutea and .74 pigs (P less than .05). The regression estimate of total response to selection for litter size was 1.06 pigs per litter (P less than .01), and the realized heritability was .15 +/- .05. When the animal model was used, the estimate of response was .48 pigs per litter. Total response in litter size to selection for ovulation rate and then litter size was estimated to be 1.8 and 1.4 pigs by the two methods. Total response to selection for decreased age at puberty was estimated to be -15.7 d (P less than .01) when data were analyzed by regression (realized heritability of .25 +/- .05) and -17.1 d using the animal model. No changes in litter size occurred in the line selected for decreased age at puberty. Analyses by regression methods and mixed-model procedures gave similar estimates of responses and very similar estimates of heritabilities.     

Effects of growth hormone-releasing factor and feed intake on energy metabolism in growing beef steers: net nutrient metabolism by portal-drained viscera and liver.

Effects of growth hormone-releasing factor (GRF) and intake on net nutrient metabolism by portal-drained viscera (PDV) and liver were measured in six growing Hereford x Angus steers fed a 75% concentrate diet at two intakes in a split-plot design with 4-wk saline or GRF injection periods within 8-wk intake periods. Daily rations were fed as 12 equal meals delivered every 2 h. Steers were injected s.c. for 21 d with either saline or 10 micrograms/kg of (1-29)NH2 human GRF at 12-h intervals. Six hourly measurements of net nutrient flux (venous-arterial concentration different [VA] x blood flow) across PDV and liver were obtained 8 to 10 d after injections began. Energy and N balances were measured using respiration calorimetry during the last week of injections. Greater intake increased blood flow (P less than .01) and net visceral release or removal of most nutrients (P less than .10). Exceptions included a decrease (P less than .10) in net PDV glucose release with greater intake in saline-treated steers and a decrease (P less than .01) in net liver removal of lactate with greater intake. Treatment of steers with GRF decreased net liver removal of alpha-amino N (AAN; P less than .05) and ammonia N (NH3N; P less than .10) and release of urea N (UN; P less than .05), increased liver release of glutamate (P less than .05), and decreased net PDV release of NH3 N (P less than .10). Decreased liver extraction ratio for AAN in GRF-treated steers (P less than .01) implies a direct effect of GRF treatment on liver metabolism separate from changes in liver AAN supply. Proportions of body N retention not accounted for by net total splanchnic AAN release increased with GRF treatment. This suggests a change in peripheral utilization of dietary AAN supply or an increase in total splanchnic N retention.     

育成期日粮蛋白质和能量水平对农大3号节粮小型蛋鸡生长性能及产蛋高峰期产蛋性能的影响

试验选用84日龄农大3号节粮小型蛋鸡540只,采用3×3因子试验设计,随机分成9个处理,每个处理5个重复。蛋白质水平分别为15%、16%、17%,代谢能水平分别为11.50、11.70、11.91 MJ/kg,旨在研究不同蛋白质和代谢能水平对农大3号节粮小型蛋鸡育成期(13～18周龄)生长以及产蛋高峰期(27～30周龄)产蛋率的影响。结果表明:育成期日粮蛋白质和能量水平对农大3号节粮小型蛋鸡生长性能和产蛋率影响差异不显著(P>0.1)。但二者存在交互作用,日粮蛋白质水平17%、能量水平11.91 MJ/kg处理组提高了育成期增重,并降低了料肉比。总之,同时提高育成期日粮蛋白质和能量水平能改善农大3号节粮小型蛋鸡群体均匀度,对生长具有积极作用。     

结构性饲料对哺乳期和断奶应激期犊牛采食量和生长性能的影响

试验旨在研究群饲犊牛自由采食酸化奶的条件下,结构性饲料对哺乳犊牛和断奶应激期犊牛生长性能的影响。选择3～5日龄、体重相近犊牛300头,随机分为6栏,每栏50头,随机选择3栏饲喂常规颗粒犊牛开食料(颗粒料组),其余3栏饲喂结构性犊牛开食料(结构料组)。两种日粮的配方完全一致。颗粒犊牛料中所有物料均经粉碎、混合、制粒,制成颗粒料。将饲粮配方中玉米和大麦取出,换为蒸汽压片玉米和带壳大麦,其余物料粉碎、混合、制粒,为颗粒浓缩料,再将颗粒浓缩料与蒸汽压片玉米、带壳大麦混合,制成结构性饲料。整个试验分为哺乳期和断奶应激期共计90 d,哺乳期试验第1 d饲喂酸化奶,第15 d供应开食料。颗粒料组犊牛在哺乳期饲喂开食料,断奶后补饲苜蓿干草。结构料组犊牛断奶后饲喂结构性生长料。将结构性开食料与20%苜蓿干草混合,制成结构性生长料。结果表明:哺乳期间,结构性饲料采食量比颗粒料组高40%(P<0.05),日增重高19%(P<0.01);断奶应激期间,结构性饲料采食量比颗粒料组高29%(P<0.01),日增重高25%(P<0.01),饲料利用效率高11%(P<0.05);试验结束时,结构料组犊牛体重更高(P<0.05)。综上所述,在哺乳期自由饮用酸化奶的条件下,结构性饲料在哺乳期和断奶应激期的效果均优于传统颗粒开食料,可促进犊牛生长,缓解断奶应激。     

Effects of administration of antimicrobials in feed on growth rate and feed efficiency of pigs in multisite production systems

OBJECTIVE: To evaluate effect of various regimens for administration of antimicrobials in feed on growth rate and feed efficiency (feed/gain) of pigs in multisite production systems. DESIGN: Controlled trial. ANIMALS: 24,099 growing pigs in 3 multisite production systems. PROCEDURE: 10 trials involving various regimens for administration of antimicrobials in feed were evaluated. Trial 1 compared effects of 2 antimicrobial regimens on finishing pig performance. Trials 2 through 10 compared growth rate and feed efficiency of nursery and finishing pigs given antimicrobials in feed with values for control pigs not given antimicrobials. RESULTS: In trial 1, no significant differences were observed between the 2 antimicrobial regimens. In the remaining trials, growth rate of nursery pigs fed antimicrobials was significantly improved, compared with growth rate of control pigs. However, growth rate of finishing pigs and feed efficiency of nursery and finishing pigs were not significantly improved by adding antimicrobials to the feed. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that use of antimicrobials in the feed to promote growth should be limited to the nursery phase in multisite pig production systems. Use of antimicrobials in the feed of finishing pigs should be limited to therapeutic applications in which a diagnosis of bacterial infection susceptible to the antimicrobial to be used has been confirmed.     

Responses in residual feed intake in lines of Large White pigs selected for growth rate on restricted feeding (measured on ad libitum individual feeding)

Residual feed intake (RFI) represents the deviation of the actual ad libitum food consumption of each animal from that predicted from combination of growth rate, backfat and metabolic body weight measurements. After 4 years of divergent selection of pigs in lines for either high or low postweaning growth rate on restricted feeding, the high line exhibited a significant reduction in RFI relative to the low line. This indicated, to some extents, a lower energy requirement for maintenance in the high than in the low line, possibly because of reduced physical activity of the animals. Estimates of genetical parameters showed that RFI was moderately heritable and those genetic correlations of RFI with carcass backfat and food conversion ratio were moderate to highly positive.     

The effect of daily energy intake on growth rate and composition of weight gain in pigs

An experiment with 29 crossbred female growing pigs (Dutch Landrace × Dutch Yorkshire) was carried out to measure the effect of daily energy intake on growth rate, N retention (according to the balance method) and composition of the weight gain. The weight gain composition was analysed by slaughtering pigs at regular intervals between 25 and 110 kg live weight. Two levels of daily energy intake, at an adequate protein intake, were used, and pigs on both treatments were slaughtered at the same age.Differences in daily energy intake affected growth rate and composition of the weight gain. Restriction of the daily energy intake by 20% caused a 15% lower live weight gain and a 12% lower N retention. Carcass muscle growth was 8% lower and fatty tissue growth was lower by 28%. Growth of bone was unaffected. Chemical analysis of different parts of the body revealed that reducing the daily energy intake by 20% caused an 8% lower protein deposition and a 28% lower fat deposition in the total body. However, there were differences between different anatomical parts of the body.Efficiency of pig meat production is discussed in relation to the effects of energy supply on weight gain composition.