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1.
An 18‐year‐old stallion was presented for castration because of insidious, bilateral scrotal enlargement of one year's duration. The left testis was firm, while the right was soft and lobulated; both were larger than normal. Palpation of the scrotum and its contents did not cause the horse to show signs of discomfort. Ultrasonography of scrotal contents revealed abnormal, heterogeneous tissue with ill defined regions of hyper‐ and hypoechogenity throughout both testes. Several hours after admission the horse developed severe signs of colic. On the basis of anamnesis, clinical findings, and results of ultrasonography and transrectal palpation bilateral testicular neoplasia and incarcerated inguinal hernia were tentatively diagnosed. Because the horse's owner did not consent to surgical treatment, the stallion was subjected to euthanasia. Histological and immunohistochemical examination of the testicular tissue collected post mortem revealed a seminoma in the left testis and a leiomyoma in the right testis. The post mortem examination also revealed incarceration of the small intestine in addition to the testicular tumours. To our knowledge, this is the first report of the simultaneous presence of bilateral, yet different testicular tumour types in a stallion.  相似文献   

2.
Scrotal enlargement is a problem in stallions that often leads to poor semen quality. Although there are many causes for scrotal enlargement, testicular neoplasia is often high on the differential list, especially in an aged stallion. This case report describes a stallion with scrotal enlargement caused by a rare neoplasia located in the tunica vaginalis, and not in the testicular parenchyma. Diagnosis of mesothelioma was made following hemicastration. Prognosis in other species is variable, but this stallion returned to his successful breeding career following treatment and has remained healthy one year following the diagnosis.  相似文献   

3.
A 15-year-old gray Arabian gelding presented for evaluation of a lateral limbal mass extending across approximately 30% of the cornea. Grossly, the raised mass appeared nonpigmented, smooth, and irregular in shape, with an area of central necrosis and serosanguinous discharge. The mass was removed via lamellar keratectomy and histopathologic evaluation revealed features characteristic of hemangiosarcoma (HSA), including irregular vascular channels lined by a plump spindle cell population. Immunohistochemistry results showed that the neoplastic cells lining the vascular channels present diffuse and strong cytoplasmic reaction with von Willebrand Factor and the perivascular spindle cells exhibit moderate cytoplasmic reaction for smooth muscle actin. A lack of cytokeratin staining definitively excluded a diagnosis of atypical squamous cell carcinoma. Smooth muscle actin staining of the perivascular cells adjacent to the neoplastic endothelial cells is not a feature commonly described in HSA and has not been reported in previous cases of equine HSA. The horse remained in good health 21 months postkeratectomy and has exceeded the survival time of previously documented equine ocular HSA cases where more extreme surgical excision was performed.  相似文献   

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5.
A 27-year-old Arabian pony gelding presented for evaluation of weight loss, intermittent sheath oedema, persistent neutropenia and thrombocytopenia, and acute left hindlimb swelling and gait abnormality. Clinical findings included swelling, heat and sensitivity localised over the left greater trochanter, mild to moderate ventral and sheath oedema, a left hindlimb post-legged gait, and off-loading of weight from the left hindlimb at rest. Initially, neutropenia and thrombocytopenia were confirmed on bloodwork, but neutrophilia and thrombocytopenia persisted as the case progressed. Diagnostic imaging (radiography and percutaneous ultrasonography) of the left hindquarters revealed an aggressive, mixed proliferative and lytic bony lesion of the proximal left femur as well as associated muscle fibre disruption and a soft tissue mass. A percutaneous core biopsy of the lesion led to the diagnosis of osteoblastic osteosarcoma on histopathology. Pain and inflammation associated with the lesion was medically managed in the hospital with mild improvement. Additionally, palliative radiation was performed under general anaesthesia. Unfortunately, before a response to palliative radiation could be assessed, the patient was subjected to euthanasia due to development of acute neurological signs.  相似文献   

6.
A Russian jumper horse presented because of an ocular perilimbal conjunctival mass and, on clinical examination, two bilateral conjunctival masses were found, of different size and conformation. Attempts at complete excision of the left eye mass and excisional biopsy of the right eye mass were performed. The left eye mass recurred rapidly, but resolved completely after topical corticosteroid therapy. The two lesions had similar histopathologic features, characterized by focal, chronic, primarily lymphocytic conjunctivitis with follicular lymphoid hyperplasia. Special histopathologic staining techniques (Gomori methenamine silver and acid fast stains) and immunohistochemistry (for CD3, BLA36 and lysozyme) failed to reveal any etiologic agents and indicated an inflammatory lesion composed of a heterogeneous population of lymphocytes and macrophages (nodular lymphocytic conjunctivitis). The lesions were indistinguishable, clinically and behaviorally, from what has been reported as 'conjunctival pseudotumor' in the horse. Equine conjunctival pseudotumor/nodular lymphocytic conjunctivitis has been reported to be unilateral and have a good prognosis after partial or complete surgical excision. This is the first reported case of bilateral nodular lymphocytic conjunctivitis in a horse and for which surgical excision alone was not curative.  相似文献   

7.
A case of paranasal sinus fibromatosis in an 11‐year‐old Thoroughbred gelding is reported. At admission the gelding underwent a unilateral frontal sinusotomy and a paranasal sinus mass was extensively debulked. The mass was diagnosed via histopathology as a desmoid fibromatosis with bone invasion, reactive osteoclastic osteolysis and osteoproliferation. The gelding had radiographic evidence of slow recurrence of the mass 8 months post operatively. The histopathological appearance and short‐term outcome are presented for this previously undiagnosed condition of the horse. Recognition of paranasal fibromatosis and the resultant differentiation from other types of paranasal sinus neoplasia may allow for improved prognostication of equine sinus lesions.  相似文献   

8.
A 15-year-old Cob mare was presented for investigation of a mandibular mass. Radiography identified an oval-shaped mass occupying the intramandibular space, with a heterogeneous osseous opacity throughout the left hemimandible. Histopathology combined with immunohistochemistry was consistent with a diagnosis of sclerosing odontogenic carcinoma, which to date has only been described, rarely, in human patients. The mass was removed using a mandibular-sparing surgical technique allowing preservation of the dental arcade. Follow-up 5 years after surgery confirmed no signs of regrowth. This case report describes the successful treatment of a previously unreported mandibular neoplasm in the horse.  相似文献   

9.
An Italian Saddle Horse mare was admitted for a hard, nonpainful mass localised in the cervical region. Clinical and diagnostic investigations were performed, which were suggestive of a multilobulated ossifying mass of neoplastic origin. Due to poor prognosis the horse was subjected to euthanasia. Post mortem computed tomography, anatomopathological examination and immunohistochemistry were used to make a definitive diagnosis of undifferentiated sarcoma in the cervical region.  相似文献   

10.
This case report describes a geriatric gelding with a 2 month history of fast‐growing masses within the parotid and submandibular regions. The horse was dyspnoeic on presentation and upper airway endoscopy revealed partial airway obstruction at the level of the pharynx, secondary to a space‐occupying mass. Cytological evaluation of multiple fine‐needle aspirates obtained from the masses were suggestive of salivary gland neoplasia, therefore the horse was subjected to humane euthanasia. A computed tomographical scan was obtained post mortem and revealed a large multi‐lobulated mass involving both guttural pouches, resulting in 80% occlusion of the naso‐ and oropharynx. Histopathology confirmed a parotid salivary gland carcinoma (papillary‐cystic type). Salivary gland tumours are extremely rare in horses, with only a few cases reported in the literature. Treatment of these malignancies proves to be challenging, requiring complete parotidectomy or surgical debulkment, in combination with adjunctive therapy.  相似文献   

11.
An 11-year-old Campolina horse was referred to the Veterinary Hospital due to the presence of an exophytic mass located in the rostral region of the mandible. Radiographic evaluation showed no evidence of tumour infiltration in the underlying mandibular bone, and the histopathology and immunohistochemical evaluations confirmed the diagnosis of fibromatous epulis. The treatment included surgical excision of the mass, followed by extensive curettage of the underlying mandibular bone. Complete healing of the wound was evidenced 60 days after the procedure; however, relapse was reported by the owner between 1 and 3 years after surgery.  相似文献   

12.
A 10‐year‐old German Warmblood gelding was referred to the Equine Department of the Vetsuisse Faculty, University of Zurich, Switzerland, for an iris mass OD, lethargy, intermittent fever, and coughing. Ophthalmic examination revealed a 7 × 9 mm raised, fleshy, whitish to pinkish, vascularized iris mass at the 2 o`clock position OD. Fundic examination showed multifocal round, brown to black, slightly raised lesions with indistinct margins and a surrounding hyperreflective zone OU. Physical examination revealed a temperature of 39.2 °C, sinus tachycardia, preputial and ventral edema, and an enlarged right mandibular lymph node. Results of a complete blood count and plasma biochemical profile showed mild anemia, leukocytosis, and thrombocytopenia. Severe splenopathy, moderate splenomegaly, and severe pulmonary pathology with nodules and large areas of consolidated lung parenchyma were observed on abdominal ultrasound and thoracic radiographs, respectively. Fine needle aspirates of the enlarged mandibular lymph node showed malignant epithelial neoplastic cells. The horse was euthanized because of the poor prognosis and subsequently underwent postmortem examination. Macroscopic necropsy and histopathology revealed an adenocarcinoma of suspected pulmonary origin with involvement of eyes, heart, liver, kidneys, spleen, diaphragm, skeletal muscles, mandibular, pulmonary, and internal iliac lymph nodes. Metastatic adenocarcinoma should be considered as a differential diagnosis in horses with iris masses, multifocal chorioretinal infiltrates, and clinical signs that conform to a paraneoplastic syndrome.  相似文献   

13.
This report describes the unusual diagnosis of a retrobulbar syncytial meningioma in a 16‐year‐old Thoroughbred gelding. The horse initially presented with unilateral left sided exophthalmos and apparent blindness characterised by unilaterally absent menace and pupillary light responses. Magnetic resonance imaging (MRI) identified a well‐defined soft tissue mass intimately associated with the optic nerve. Based on the characteristic MRI appearance, a meningioma was suspected. The eye was enucleated under general anaesthesia and partial excision of the mass was achieved. Histopathology confirmed the diagnosis and the horse underwent a course of adjuvant radiotherapy. Twelve months following surgery the horse is back in work, no neurological abnormalities have been detected and follow‐up computed tomographic imaging of the skull has revealed mild bone sclerosis with no remnants of the mass identified.  相似文献   

14.
Cutaneous haeangiomas are benign vascular neoplasms that arise from endothelial cells of blood vessels. Haemangiomas account for 0.6%–4% of all equine cutaneous neoplasms and the fetlock is the most commonly affected site. We describe the use of computed tomography angiography (CTA) for the evaluation of a cutaneous haemangioma located on the plantarolateral aspect of the left hindlimb fetlock of a 9-month-old Standardbred colt. Computed tomography angiography of the affected fetlock was performed under general anaesthesia. The medial plantar artery was catheterised and a total volume of 50 ml of iodinated non-ionic contrast medium (Iopamidol, 300 mg I/ml, Bracco Imaging Canada) was injected at a rate of 2 ml/s. Following contrast medium administration, the dorsal metatarsal artery and branches including the lateral and medial digital arteries were well demarcated. Two smaller lateral and medial arteries were also identified, forming the vascular network of the metatarsophalangeal joint. At the level of the haemangioma, two tortuous arteries arising from the lateral digital artery were identified, in addition to multiple small branches from nearby cutaneous arteries. These vessels supplied the homogeneously strongly contrast-enhancing cutaneous mass. The initial goal of the CTA study was to map the vascular anatomy for arterial embolisation in conjunction with pharmacological therapy. Considering the involvement of multiple small arterial branches, complete surgical excision along with ligation of the two main supplying arteries was alternatively elected, resulting in a successful long-term outcome.  相似文献   

15.
A primary ossifying fibroma was found at necropsy in a 5-year-old Welsh pony cross mare that was humanely subjected to euthanasia for an intractable severe left hindlimb lameness. Antemortem radiographs of the left hind pastern were characterised by articular, subchondral and cortical areas of lysis. Primary ossifying fibroma is a rare lesion of the distal limb but should be considered when there is extensive lysis extending into the medulla and proximal cortical bone.  相似文献   

16.
An 18‐year‐old Quarter Horse gelding was examined for haematuria of 6 weeks' duration. Rectal examination identified an enlarged left kidney and ultrasonographic examination of the kidney identified grossly abnormal renal architecture. Hand‐assisted laparoscopic nephrectomy was performed following laparoscopic exploration of the abdomen for metastatic disease. A laparoscopic stapling device was successfully used to transect and ligate the renal vasculature and ureter. Histopathological examination of the kidney identified renal cell carcinoma. A 7 month survival was documented following surgery. Unilateral nephrectomy should be considered a therapeutic or palliative procedure for horses with renal cell carcinoma.  相似文献   

17.
A case of renal tubular carcinoma with bone metaplasia is reported in a 20-year-old male, mixed breed horse having a history of weight loss and hematuria. This report includes the clinical signs, macroscopic and microscopic lesions, and the immunohistochemical findings of this neoplasm.  相似文献   

18.
A 10-year-old Quarter Horse gelding presented for a large, slowly growing mass in the right thoracic region caudal to the withers (approximately at the level of thoracic vertebrae 10 to 16). The mass was surgically removed, the horse returned to normal riding activity, and no external regrowth was observed. Two years after surgery, the horse developed progressive signs of hindlimb weakness, ataxia and adopting a dog-sitting stance. Post-mortem examination confirmed spinal canal infiltration and spinal cord compression (at the level of the 12th thoracic vertebra) by a similar soft tissue sarcoma as diagnosed previously. Immunohistochemistry confirmed the tumour as a peripheral nerve sheath tumour (PNST) likely originating from the twelfth thoracic spinal nerve. This report demonstrates that with incomplete tumour resection, local recurrence and extension of a PNST into the central nervous system can occur even years after initial tumour removal. Immunohistochemistry to differentiate the type of soft tissue sarcoma in cases with close association to the nervous system may prove beneficial to anticipate this uncommon complication. Early surgical resection with adjunctive therapies should be considered in these cases.  相似文献   

19.
A one‐year‐old, Thoroughbred colt presented for evaluation due to a one month history of fever of unknown origin and progressive weight loss. On initial presentation, the horse was febrile and showed signs localised to the respiratory tract. These included bilaterally increased bronchovesicular sounds and a moderate, diffuse interstitial pattern on thoracic radiographs. A transtracheal wash yielded mucopurulent debris, culture of which grew small numbers of Staphylococcus epidermidis and Aspergillus spp. The horse was discharged with a diagnosis of bronchointerstitial pneumonia and placed on antibiotic therapy. Ten days after initial presentation, he developed abdominal pain that was unresponsive to on‐farm treatment. The horse was febrile, displayed increased respiratory rate and effort, and showed moderate signs of abdominal pain. On rectal examination, a firm, 8–10 cm mass was palpated on midline. The colt was admitted to the hospital and scheduled for exploratory laparotomy, but died a short time later before surgery could be performed. This report describes the clinical, diagnostic and histopathological findings of a case of alimentary lymphoma in a yearling colt.  相似文献   

20.
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