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1.
Tundis R Loizzo MR Menichini F Bonesi M Conforti F Statti G De Luca D de Cindio B Menichini F 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(3):261-269
The present study aimed to evaluate for the first time the phenols, flavonoids, carotenoids, capsaicin and dihydrocapsaicin
content and the antioxidant and hypoglycemic properties of Capsicum annuum var. acuminatum small and C. annuum var. cerasiferum air-dried fruits. The ethanol extract of C. annuum var. acuminatum small, characterized by the major content of total poliphenols, flavonoids, carotenoids and capsaicinoids, showed the highest
radical scavenging activity (IC50 of 152.9 μg/ml). On the contrary, C. annuum var. cerasiferum showed a significant antioxidant activity evaluated by the β-carotene bleaching test (IC50 of 3.1 μg/ml). The lipophilic fraction of both C. annuum var. acuminatum and C. annuum var. cerasiferum exhibited an interesting and selective inhibitory activity against α-amylase (IC50 of 6.9 and 20.1 μg/ml, respectively). 相似文献
2.
Hong Y Lin S Jiang Y Ashraf M 《Plant foods for human nutrition (Dordrecht, Netherlands)》2008,63(4):200-204
Eriobotrya plants are known to have significant amounts of phenolics and flavonoids, and exhibit a strong antioxidant activity. Experiments
were conducted to examine variation in the contents of total phenolics and flavonoids, and antioxidant activities in the leaves
of 11 Eriobotrya species (Tibet loquat, Daduhe loquat, Hengchun loquat, Taiwan loquat, Oak leaf loquat, Bengal loquat, Fragrant loquat, Guangxi
loquat, Obovate loquat, Big flower loquat, and common loquat, the last species include two materials, one is a cultivar ‘Zaozhong
6’, another is a wild tree). In these species, ‘Zaozhong 6′ loquat is a cultivar. The leaf extracts of ‘Tibet’, ‘Obovate’,
‘Taiwan’, ‘Bengal’ and ‘Hengchun’ loquats exhibited significantly higher contents of total flavonoids and total phenolics,
compared with those of other species. Of these 11 species, the highest contents of total phenolics and total flavonoids were
observed in ‘Tibet’ and ‘Obovatae’ loquats, respectively. The significantly stronger antioxidant abilities assessed by the
DPPH radical scavenging activity and reducing power were obtained in the leaf extracts of ‘Taiwan’, ‘Tibet’, ‘Bengal’, ‘Oak
leaf’, ‘Hengchun’ and ‘Obovate’ loquats, compared with the other species. In addition, significant correlations were found
between the contents of total phenolics or flavonoids and DPPH radical scavenging activity/reducing power. This work indicates
that the leaf extracts of the wild Eriobotrya species, ‘Tibet’, ‘Obovatae’, ‘Taiwan’, ‘Bengal’, ‘Oak leaf’ and ‘Hengchun’ loquats, exhibited significantly higher levels
of total phenolics and flavonoids, and significantly stronger antioxidant activities, compared with the cultivated species,
‘Zaozhong 6′ loquat, which suggests that these wild species have a better utilization value. 相似文献
3.
Jimenez M Guzman AP Azuara E Garcia O Mendoza MR Beristain CI 《Plant foods for human nutrition (Dordrecht, Netherlands)》2012,67(1):57-63
Porophyllum tagetoides is an annual warm-weather herb that has an intense typical smell. Its leaves are commonly used in soup preparation and traditional
medicine for treatment of inflammatory diseases. Its volatile compounds and antioxidant properties were evaluated in crude,
aqueous and ethanol leaf extract and an oil emulsion using different antioxidant assays in vitro, such as: DPPH radical scavenging activity, redox potential, polyphenol content, reducing power and optical density. A high
antioxidative activity was found when comparing leaves with stems. The crude extract from leaves showed a very high reducing
power (2.88 ± 0.20 O.D.) and DPPH radical-scavenging activity (54.63 ± 4.80%), in concordance with a major concentration of
vitamin C (23.97 ± 0.36 mg/100 g). Instead, the highest polyphenol content (264.54 ± 2.17 mg GAE/g of sample) and redox potential
(561.23 ± 0.15 mV) were found by the ethanol and aqueous extract, respectively. Aldehydes and terpenes such as nonanal, decanal,
trans-pineno, β-myrcene and D-limonene were the major volatiles found. This study suggests that Porophyllum tagetoides extracts could be used as antioxidants. 相似文献
4.
Dias MI Barros L Sousa MJ Ferreira IC 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(2):181-186
Coriander is commonly used for medicinal purposes, food applications, cosmetics and perfumes. Herein, the production of antioxidants
in vegetative parts (leaves and stems) of in vivo and in vitro grown samples was compared. In vitro samples were clone A- with notorious purple pigmentation in stems and leaves and clone B- green. Seeds were also studied
as they are used to obtain in vivo and in vitro vegetative parts. Lipophilic (tocopherols, carotenoids and chlorophylls) and hydrophilic (sugars, ascorbic acid, phenolics,
flavonols and anthocyanins) compounds were quantified. The antioxidant activity was evaluated by radical scavenging activity,
reducing power and lipid peroxidation inhibition. The in vivo sample showed the highest antioxidant activity mainly due to its highest levels of hydrophilic compounds. Otherwise, in vitro samples, mainly clone A, gave the highest concentration in lipophilic compounds but a different profile when compared to
the in vivo sample. Clones A and B revealed a lack of β-carotene, β- and δ-tocopherols, a decrease in α-tocopherol, and an increase in
γ-tocopherol and clorophylls in comparison to the in vivo sample. In vitro culture might be useful to explore the plants potentialities for industrial applications, controlling environmental conditions
to produce higher amounts of some bioactive products. 相似文献
5.
Lee BB Cha MR Kim SY Park E Park HR Lee SC 《Plant foods for human nutrition (Dordrecht, Netherlands)》2007,62(2):79-84
Organic solvent (methanol, ethanol, and acetone) extracts and water extracts of cherry (Prunus serrulata var. spontanea) blossoms were prepared, and antioxidant activities of the extracts were evaluated. Methanolic CBE (100 μg/ml) showed the
highest total phenol content (104.30 μM), radical scavenging activity (34.2%), and reducing power (0.391). The effect of CBE
on DNA damage induced by H2O2 in human leukocytes was evaluated by Comet assay. All CBE was a potent dose dependent inhibitor of DNA damage induced by
200 μM of H2O2, methanolic CBE showed the most strong inhibition activity. The methanolic CBE of 500 μg/ml showed 38.8% inhibition against
growth of human colon cancer cell line HT-29. These results indicated that cherry blossoms could provide valuable bioactive
materials. 相似文献
6.
Santos-Cervantes ME Ibarra-Zazueta ME Loarca-Piña G Paredes-López O Delgado-Vargas F 《Plant foods for human nutrition (Dordrecht, Netherlands)》2007,62(2):71-77
We report for the first time the antioxidant and antimutagenic activities of fractions from Randia echinocarpa fruit, which is a Rubiaceae plant native to Sinaloa, Mexico. This fruit has been traditionally used in the prevention or treatment of cancer, among other
diseases. The pulp of the fruit was sequentially extracted with solvents of different polarity (i.e. hexane, chloroform, methanol
and water). A high extraction yield was obtained with methanol (72.17% d.w.). The aqueous extract showed the highest content
of phenolics (2.27 mg/g as ferulic acid equivalents) and the highest antioxidant activity based on the β-carotene bleaching
method (486.15). The commercial antioxidant BHT was used as control (835.05). Antimutagenic activity of the aqueous extract
(0–500 μg/tube) was evaluated using the Salmonella microsuspension assay (YG1024 strain) and 1-NP as the mutagen (50 and 100 ng/tube). The aqueous extract was neither toxic
nor mutagenic and the percentage of inhibition on 1-NP mutagenicity was 32 and 53% at doses of 50 and 100 ng/tube, respectively.
The results of the double incubation assay suggest that the extract inhibited the mutagenicity of 1-NP by a combination of
desmutagenic and bioantimutagenic effects. 相似文献
7.
Pahua-Ramos ME Ortiz-Moreno A Chamorro-Cevallos G Hernández-Navarro MD Garduño-Siciliano L Necoechea-Mondragón H Hernández-Ortega M 《Plant foods for human nutrition (Dordrecht, Netherlands)》2012,67(1):10-16
Avocado seed contains elevated levels of phenolic compounds and exhibits antioxidant properties. We investigated the effect
of Avocado Seed Flour (ASF) on the lipid levels in mice on a hyperlipidemic diet. The concentration of phenols was determined
by high-performance liquid chromatography, antioxidant activity was evaluated using the Trolox equivalent antioxidant capacity
method, and dietary fiber was measured using the Association of Official Analytical Chemists (AOAC) method. The LD50 of ASF was determined using Lorke’s method and hypolipidemic activity was evaluated in a hypercholesterolemic model in mice.
Protocatechuic acid was the main phenolic compound found in ASF, followed by kaempferide and vanillic acid. The total phenolic
content in the methanolic extract of ASF was 292.00 ± 9.81 mg gallic acid equivalents/g seed dry weight and the antioxidant
activity resulted in 173.3 μmol Trolox equivalents/g DW. In addition, a high content of dietary fiber was found (34.8%). The
oral LD50 for ASF was 1767 mg/kg body weight, and treatment with ASF significantly reduced the levels of total cholesterol, LDL-C,
and prediction of the atherogenic index. Therefore, the antioxidant activity of phenolic compounds and dietary fiber in ASF
may be responsible for the hypocholesterolemic activity of ASF in a hyperlipidemic model of mice. 相似文献
8.
Ban X Huang B He J Chen Y Zeng H Han L Wang Y 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(2):175-180
The inflorescence of cultivated Coptis chinensis has been valued for tea production for many years in China. The antioxidant activities of C. chinensis inflorescence extracts prepared by various solvents were investigated by using several established in vitro systems: 2,2′-azinobis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS), α,α-diphenyl-β-picrylhydrazyl (DPPH) and superoxide
radical scavenging assays, reducing power assay, and ferrothiocyanate (FTC) and thiobarbituric acid (TBA) assays. The results
showed that the 70% ethanol extract (EE) had the strongest antioxidant activity in vitro among the various extracts. Based on the in vitro results, EE was used to evaluate the antioxidant activity of C. chinensis inflorescence in vivo. The liver and kidney of intoxicated animals showed a significant decrease in superoxide dismutase (SOD), catalase (CAT)
and glutathione (GSH) levels, while the malondialdehyde (MDA) level showed a significant increase. These changes were significantly
reversed after treatment with EE and the standard vitamin E. Thus, the C. chinensis inflorescence may be a valuable natural source that can be applicable to food industries. 相似文献
9.
Rocha Ribeiro SM Queiroz JH Lopes Ribeiro de Queiroz ME Campos FM Pinheiro Sant'ana HM 《Plant foods for human nutrition (Dordrecht, Netherlands)》2007,62(1):13-17
This work was carried out to investigate the pulp composition of four mango cultivars (Haden, Tommy Atkins and Ubá) at the
ripening stage in relation to three components with antioxidant potential (total phenolics, carotenoids and ascorbic acid).
Total phenolic compound content was estimated by the Folin-Ciocalteu reagent and total carotenoid content by spectrophotometry
at 450 nm. The contents of β-carotene and total vitamin C (ascorbic acid and dehydroascorbic acid) were quantified by high performance liquid chromatography.
Differences were found among the four mango cultivars in all the components analyzed. The content of phenolic compounds ranged
from 48.40 (Haden) to 208.70 mg/100 g (Ubá); total carotenoid from 1.91 (Haden) to 2.63 mg/100 g (Palmer); β-carotene from 661.27 (Palmer) to 2,220 μg/100 g (Ubá) and total ascorbic acid ranged from 9.79 (Tommy Atkins) to 77.71 mg/100 g
(Ubá). These results corroborated previous information that mangoes are a good source of antioxidants in human diet. 相似文献
10.
Gene E. Lester John L. Jifon Kevin M. Crosby 《Plant foods for human nutrition (Dordrecht, Netherlands)》2009,64(3):205-211
Muskmelons (Cucumis melo L.) are well-known as excellent sources of several vitamins, minerals and non-enzymatic antioxidant phytochemicals such as
vitamin C and pro-vitamin A. Less well-studied is their potential role as sources of enzymatic antioxidants such as superoxide
dismutase (SOD), which have been associated with enhanced reactive oxygen species scavenging capacity in some muskmelon fruits.
In this study, we investigated the variability in SOD activities among diverse advanced breeding lines and commercial muskmelon
cultivars grown in two different soil types—clay or sandy loam. Specific and total SOD activities varied significantly among
the genotypes (P ≤ 0.001), compared to soil type (P ≤ 0.055). Netted (cantaloupe) genotypes generally had the lowest SOD activities compared to the green- and orange-fleshed
honey dew types. Casaba type fruit had average SOD activities that were ∼ 1.6-fold greater than those of honey dew types,
and ∼ 9.0-fold greater than those of cantaloupe types. These data indicate there is useful genetic diversity among commercial
melon varieties and in exotic genotypes that could be used to develop C. melo as a functional food with enhanced SOD content. 相似文献
11.
Pandino G Lombardo S Mauromicale G 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(3):291-297
The globe artichoke is a widely consumed vegetable in the Mediterranean Basin, with Italy being the leading producer. In southern
Italy, its cultivation contributes to local economic stability and social development. The producers are increasingly choosing
to replace autochthonous varieties, such as ‘Violetto di Sicilia’, with cultivars bred or selected outside of the region,
putting pressure on the maintenance of traditional varieties. Here, we have undertaken a detailed morphological and chemical
analysis of a group of clones selected from a population of ‘Violetto di Sicilia’. All the traits measured displayed genetic
variation, particularly the total content of phenolics and minerals. The capitula of the ‘Violetto di Sicilia’ clones contained,
on average, 6.3 g kg−1 of fresh weight total phenolics, compared with 4.5 g kg−1 in the two commercial varieties. The clones also had more inulin than commercial varieties (254 vs. 225 g kg−1 of dry matter), as well as a good mineral content. The set of clones is of interest in the context of the proposed improvement
of the crop through breeding and selection of genotypes with high nutritional quality and a specific end-use (industrial processing
or fresh consumption). 相似文献
12.
Mario Sanz-Penella J Laparra JM Sanz Y Haros M 《Plant foods for human nutrition (Dordrecht, Netherlands)》2012,67(1):50-56
The objective of the present study was to evaluate the effect of the bread supplemented with whole amaranth flour (0, 20 and
40%) on iron bioavailability using Caco-2 cells model. The phytate and lower myo-inositol phosphates content in in vitro bread digests were measured by high pressure liquid chromatography. The breads made with amaranth showed significant increase
of soluble phytates levels (up to 1.20 μmol/g in dry matter for the 40% of substitution) in comparison with controls, which have not detectable values. A negative
correlation among phytate and Fe availability was found when increased levels of amaranth. Ferritin concentration was found
2.7- and 2.0-fold higher (P < 0.05) in cultures exposed to 20% and 40% of amaranth formulated bread samples, respectively, compared to control bread.
The soluble phytate/Fe molar ratio explained the whole amaranth flour-mediated inhibitory effect associated to the limitation
of available Fe; however, the use up to 20% of amaranth in bread formulation appears as a promising strategy to improve the
nutritional value of bread, as indicated by the ferritin concentrations quantified in cell cultures. Higher proportion of
amaranth flour increased Fe concentration although there was not detected any increase in Fe uptake. 相似文献
13.
Juan Fernando Pío-León Gabriela López-Angulo Octavio Paredes-López Magdalena de Jesús Uribe-Beltrán Sylvia Páz Díaz-Camacho Francisco Delgado-Vargas 《Plant foods for human nutrition (Dordrecht, Netherlands)》2009,64(3):181-187
Bromelia pinguin L. is a plant native to Sinaloa, Mexico, where its fruit is used as food or as a phytotherapeutic agent. The fruits of B. pinguin were characterized and they could be considered as a functional food. These fruits show an average weight of 13.7 g and a
yellow color of high luminosity (b* = 43.2, L* = 74.5). The values for acidity (4.6%, as citric acid) and pH (3.7) of B. pinguin fruit are similar to those of citrics. The edible portion is characterized by a high content of vitamin C (126 mg/100 g),
ash (10.6 g/100 g d.w.), crude fiber (3.4 g/100 g d.w.), calcium (1290 mg/100 g d.w.), magnesium (500 mg/100 g d.w.), manganese
(2.95 mg/100 g d.w.) and it is a good source of zinc (2.8 mg/100 g d.w.). Polar fractions extracted from the pulp fruit showed
activity against several genera of human pathogenic-bacteria (Staphylococcus, Streptococcus, Enterococcus, Salmonella, Shigella, Escherichia and Pseudomonas). 相似文献
14.
Fares R Bazzi S Baydoun SE Abdel-Massih RM 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(1):58-63
It is becoming increasingly evident that certain phytochemicals possess cancer chemopreventive properties. In this study,
the anti-proliferative activity of plant extracts from olive (Olea europaea L.) leaves was tested on human leukemic cell line (Jurkat). Cytotoxicity of various concentrations of plant extracts was examined
and the IC50 was determined. Olive leaf extracts showed concentration-dependent anti-proliferative effect as determined by the WST-1 proliferation
kit and [3H]-thymidine incorporation method. To study whether cell death was due to apoptosis, cells were stained with Annexin V-FITC
and PI and the expression of important regulatory proteins (Bcl-2, Bax, and p53) involved in apoptosis were examined by Western
blot. The antioxidant activity of olive leaves (SC50 = 0.1 mg dry weight) was studied using the DPPH scavenging method. Present findings suggest that olive leaves extracts exhibit
anti-proliferative effect on leukemic cells by inducing apoptosis. 相似文献
15.
Monica Rosa Loizzo Ataa Said Rosa Tundis Usama W. Hawas Khaled Rashed Federica Menichini Natale Giuseppe Frega Francesco Menichini 《Plant foods for human nutrition (Dordrecht, Netherlands)》2009,64(4):264-270
The object of the study was to determine the chemical composition of Diospyros lotus L. extract and their antioxidant and antiproliferative properties. Eight compounds were isolated from D. lotus and identified as gallic acid, methylgallate, ellagic acid, kaempferol, quercetin, myricetin, myricetin 3-O-β-glucuronide, and myricetin-3-O-α-rhamnoside. D. lotus extract tested in different in vitro systems (DPPH, ABTS, FRAP, and Fe2+ chelating activity assay) showed significant antioxidant activity. The potential antiproliferative properties of D. lotus extract and isolated compounds against nine human cancer cell lines such as COR-L23, CaCo-2, C32, ACHN, A375, A549, Huh-7D12,
MCF-7, and LNCaP were investigated in vitro by SRB assay. D. lotus extract demonstrated the highest inhibitory activity against COR-L23 with an IC50 value of 12.2 μg/ml. Among identified hydrolysable tannins, ellagic acid evidenced strong antiproliferative activity against
both C32 and A375 cells with IC50 values of 0.8 and 4.1 μg/ml, respectively. Interesting results were observed, also, with gallic acid that showed the highest
cytotoxic activity against CaCo-2 (IC50 2.6 μg/ml). Overall, the results of this study suggest that D. lotus displays a good antioxidant activity and has antiproliferative effects. Both activities are related to identified phenolic
compounds. 相似文献
16.
17.
Jing Z. Dong Da Y. Lu Y. Wang 《Plant foods for human nutrition (Dordrecht, Netherlands)》2009,64(3):199-204
Leaves of Lycium barbarum are widely used as medicine vegetables and functional tea in China. The main flavonoids present in the leaves were separated
and identified by high performance liquid chromatography (HPLC), liquid chromatography-atmospheric pressure chemical ionization
mass spectrometry (LC-(APCI) MS) and ultraviolet-visible spectra with shift additives. The predominant flavonoid was identified
as rutin. Leaves are the rutin-rich parts (16.03–16.33 mg/g). In the wild and cultivated L. barbarum fruits, contents of rutin were determined very low (0.09–1.38 mg/g). The contents of total flavonoids (21.25 mg/g) of cultivated
L. barbarum leaves were much higher than those in the wild L. barbarum leaves (17.86 mg/g), so cultivated barbarum leaves are a suitable source for medicine vegetables and functional tea. 相似文献
18.
Beato VM Orgaz F Mansilla F Montaño A 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(3):218-223
The contents of total phenolic compounds, flavonoids, and phenolic acids were determined in selected garlic cultivars grown
at four locations. The total phenolic content varied from 3.4 mg gallic acid equivalents (GAE)/g of dry matter (dm) to 10.8 mg
GAE/g of dm with a mean value of 6.5 mg GAE/g of dm. The myricetin, quercetin, kaempferol, and apigenin flavonoids were not
detected in any of the samples. Caffeic acid and ferulic acid were the major phenolic acids found with mean values of 2.9 mg/kg
of dm and 2.6 mg/kg of dm, respectively. The mean contents of vanillic, p-hydroxybenzoic, and p-coumaric acids were comparable (0.4–0.8 mg/kg of dm), and the level of sinapic acid was negligible (< 0.1 mg/kg of dm). There
was a significant effect of location but an insignificant effect of genotype on contents of caffeic, vanillic, p-hydroxybenzoic, and p-coumaric acids. However, genotype but not location affected the contents of total phenolics and ferulic acid. On average,
the white garlic cultivars and Chinese garlic cultivars contained higher contents of total phenolics and ferulic acid than
the purple garlic cultivars. However, the differences in the total phenolic content between the purple and white garlic cultivars
were not significant. 相似文献
19.
Korekar G Stobdan T Arora R Yadav A Singh SB 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(4):376-383
Fourteen apricot genotypes grown under similar cultural practices in Trans-Himalayan Ladakh region were studied to find out
the influence of genotype on antioxidant capacity and total phenolic content (TPC) of apricot kernel. The kernels were found
to be rich in TPC ranging from 92.2 to 162.1 mg gallic acid equivalent/100 g. The free radical-scavenging activity in terms
of inhibitory concentration (IC50) ranged from 43.8 to 123.4 mg/ml and ferric reducing antioxidant potential (FRAP) from 154.1 to 243.6 FeSO4.7H2O μg/ml. A variation of 1–1.7 fold in total phenolic content, 1–2.8 fold in IC50 by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and 1–1.6 fold in ferric reducing antioxidant potential among the examined
kernels underlines the important role played by genetic background for determining the phenolic content and antioxidant potential
of apricot kernel. A positive significant correlation between TPC and FRAP (r = 0.671) was found. No significant correlation was found between TPC and IC50; FRAP and IC50; TPC and physical properties of kernel. Principal component analysis demonstrated that genotypic effect is more pronounced
towards TPC and total antioxidant capacity (TAC) content in apricot kernel while the contribution of seed and kernel physical
properties are not highly significant. 相似文献
20.
Eustolia Rodríguez-Muñoz Gilberto Herrera-Ruiz Gustavo Pedraza-Aboytes Guadalupe Loarca-Piña 《Plant foods for human nutrition (Dordrecht, Netherlands)》2009,64(1):46-51
Natural oleoresins rich in lycopene were obtained from two varieties of tomato (Zedona and Gironda) and their nutraceutical
potential (antioxidant and antimutagenic capacity) was evaluated. Both oleoresins had a high content of lycopene, 58.33 ± 1.67 mg/g
(Zedona) and 63.97 ± 0.80 mg/g (Gironda). The antioxidant activity (AA) of the oleoresins by β-carotene method were 56.4–74.5%
(Zedona) and 51–72.8% (Gironda), while when using the free radical stable 2,2-diphenyl-picryl-hydrazyl (DPPH) method, the
antiradical activity (ARA) was determined to be 18.2–32.7% (Zedona) and 16.6–26.7% (Gironda) for the concentrations tested
that of 200–400 μM equivalents of lycopene. The antimutagenic activity of the oleoresins was tested against aflatoxin B1 (AFB1) using the microsuspension assay, both varieties had a very high antimutagenic potential against AFB1 (60–66%).These results suggest the NCRT can be taken advantage to obtaining rich oleoresin in lycopene with a nutraceutical
value. 相似文献