(−)-α-Bisabolol attenuates visceral nociception and inflammation in mice

The study examined the antiinflammatory and antinociceptive effects of the sesquiterpene (−)-α-bisabolol (BISA). The antiinflammatory effect was evaluated on acute models of dermatitis induced by Croton oil, arachidonic acid, phenol and capsaicin, respectively, in mouse ear. BISA inhibited the dermatitis induced by all noxious agents, except capsaicin. BISA was assessed in two established mouse models of visceral nociception. Mice were pretreated orally with BISA, and the pain-related behavioral responses to intraperitoneal cyclophosphamide or to intracolonic mustard oil were analyzed. BISA showed a dose-unrelated significant antinociception. Collectively, the results suggest that BISA may be an topical antiinflammatory and visceral antinociceptive agent.     

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice

The anti-inflammatory activity of zerumbone (1), a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith was investigated using carrageenan-induced paw edema and cotton pellet-induced granuloma tissue formation test in mice. It was demonstrated that intraperitoneal administration of 1 at a dose of 5, 10, 50 and 100 mg/kg produced significant dose-dependent inhibition of paw edema induced by carrageenan. It was also demonstrated that 1 at similar doses significantly suppressed granulomatous tissue formation in cotton pellet-induced granuloma test.     

Antioxidative and acute antiinflammatory effects of Torreya grandis

The present study was undertaken to investigate the antioxidative and antiinflammatory activities of the ethanolic extract of seeds of Torreya grandis (EST). Exposure of human dermal fibroblasts to the extract at 50 and 250 microg/ml showed significant protective effect against hydrogen peroxide (300 microM). EST not only protected cell survival from H(2)O(2)-induced toxicity, but also inhibited the H(2)O(2)-induced LDH release significantly. It was also found that EST at 100 and 1000 microg/ml showed scavenging activities of radicals and reactive oxygen species with 29.8% and 100.0% of inhibition against DPPH radical and 41.2% and 98.4% against superoxide radicals in the xanthine/xanthine oxidase system, respectively. Topically applied EST dose-dependently inhibited arachidonic acid (AA)- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edema in mice.     

Anti-inflammatory activity of Butea monosperma flowers

Methanolic extract of Butea monosperma flowers (MEBM) was studied for anti-inflammatory activity against carrageenin induced paw edema and cotton pellet granuloma in albino rats. In carrageenin induced paw edema, MEBM at oral doses of 600 mg/kg and 800 mg/kg, dose-dependently inhibited the paw edema. In cotton pellet induced granuloma, MEBM at the same doses was found to significantly inhibit granuloma tissue formation, including significant reduction in levels of serum lysosomal enzymes (SGOT, SGPT and ALP) and lipid peroxides as compared to control.     

抓住机遇,迎接挑战,促进西双版纳茶业发展

分析我国加入WTO后茶业的机遇和面临的严竣问题 ,提出西双版纳茶业发展应加速低产茶园改造 ,推广无性系良种 ;保护茶园生态 ,应用生物技术 ;调整产品结构 ,开拓国内外市场 ;建立龙头产业 ,实施名牌战备等四项建议。随着中国加入WTO步伐的加快 ,为我国茶叶出口创造了前所未有的机遇 ,中国是世界产茶大国 ,19世纪几乎垄断了整个世界茶叶市场 ,进入 2 0世纪 ,肯尼亚、斯里兰卡后来居上。 1999年全国茶叶产量达 6 8万t,出口仅2 0 .2 9万t,云南茶叶产量 7.5万t,出口仅 1.0 3万t,版纳茶叶产量 1.5万t,几乎全部内销。国茶出口不畅 ,其主要原因是受经营机制和产品质量的制约 ,如何抓住中国加入WTO的机遇 ,振兴国茶在国际市场的声誉 ,促进版纳茶业再上新台阶 ,必须认真分析存在的问题 ,改革现行茶叶经营机制 ,依靠科技进步 ,提高产品的产量和质量