《兽医临床诊断学》教学改革效果分析

对近3年<兽医临床诊断学>教学改革的效果进行了分析,具体包括教学方法改革效果、实践教学改革效果、考核方式改革效果以及其他方面的改革效果,旨在为兽医临床诊断学及其他课程教学提供有益参考.     

Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document

In veterinary medical oncology, there is currently no standardized protocol for assessing response to therapy in solid tumours. The lack of such a formalized guideline makes it challenging to critically compare outcome measures across various treatment protocols. The Veterinary Cooperative Oncology Group (VCOG) membership consensus document presented here is based on the recommendations of a subcommittee of American College of Veterinary Internal Medicine (ACVIM) board‐certified veterinary oncologists. This consensus paper has used the human response evaluation criteria in solid tumours (RECIST v1.1) as a framework to establish standard procedures for response assessment in canine solid tumours that is meant to be easy to use, repeatable and applicable across a variety of clinical trial structures in veterinary oncology. It is hoped that this new canine RECIST (cRECIST v1.0) will be adopted within the veterinary oncology community and thereby facilitate the comparison of current and future treatment protocols used for companion animals with cancer.     

兽医临床实例训练课程教学与考核模式的探索

兽医临床实例训练是安徽农业大学动物医学专业近几年新开设的一门实践课程。该课程以学校动物医院为实践平台,以提高学生的动手操作技能,增强临床实践能力,培养学生的临床思维能力和初步职业素质为目标,通过在教学过程中不断地实践和完善,探索出一套合理的、先进的教学与考核模式。该模式取得了明显的教学效果,为兽医临床实践教学改革提供了新思维和新方法。     

《兽医临床诊断学》在线开放课程建设与应用

在线开放课程建设和应用是我国高等教育实现变轨超车的重要抓手。该文介绍了福建省精品在线开放课程《兽医临床诊断学》的建设和应用,为高校教师进行在线开放课程建设、开展混合式教学、翻转课堂教学等提供参考。     

病例教学法在兽医临床诊断学教学中的探索与实践

兽医临床诊断学是动物医学专业重要的专业基础课,具有很强的实践性。通过病例教学法的实施,有效的激发了学生学习兴趣,培养了学生临床思维的能力,提高了教学效果。本文结合兽医临床诊断学的特点,总结近年来的教学成果,介绍了病例教学法在课程教学中的意义、实施方法及注意事项等,以期进一步提高兽医临床诊断学的教学效果。     

证候类中兽药临床研究思考

阐述了证候类中兽药临床研究的主要内容和常见问题,提出了提高证候类中兽药临床研究水平的措施,可为该类新兽药的研发提供临床研究基本思路和参考.     

Placebo Effect in Canine Epilepsy Trials

Background: The placebo effect is a well-recognized phenomenon in human medicine; in contrast, little information exists on the effect of placebo administration in veterinary patients.
Hypothesis: Nonpharmacologic therapeutic effects play a role in response rates identified in canine epilepsy trials.
Animals: Thirty-four dogs with epilepsy.
Methods: Meta-analysis of the 3 known prospective, placebo-controlled canine epilepsy trials. The number of seizures per week was compiled for each dog throughout their participation in the trial. Log-linear models were developed to evaluate seizure frequency during treatment and placebo relative to baseline.
Results: Twenty-two of 28 (79%) dogs in the study that received placebo demonstrated a decrease in seizure frequency compared with baseline, and 8 (29%) could be considered responders, with a 50% or greater reduction in seizures. For the 3 trials evaluated, the average reduction in seizures during placebo administration relative to baseline was 26% ( P = .0018), 29% ( P = .17), and 46% ( P = .01).
Conclusions and Clinical Importance: A positive response to placebo administration, manifesting as a decrease in seizure frequency, can be observed in epileptic dogs. This is of importance when evaluating open label studies in dogs that aim to assess efficacy of antiepileptic drugs, as the reported results might be overstated. Findings from this study highlight the need for more placebo-controlled trials in veterinary medicine.     

临床与科研在兽医诊断学教学中的应用探索

兽医诊断学是兽医专业一门实践性很强的专业基础课,它不仅包含丰富的理论知识,也涵盖了许多临床诊断、实验室诊断以及放射学诊断等操作技能。为了加强学生临床诊断的实践能力,培养出更多优秀的兽医人才,结合目前理论教学和实验教学的现状和问题,对教学大纲进行改善和调整,探讨兽医诊断学课程以临床病例落实理论教学,科学研发引领实验教学的实施与应用效果。     

一种新型微生态保健品在兽医临床中的应用研究

利用一种微生态保健品和3种抗菌素药物，即氟哌酸、氯霉素、庆大霉素在兽医临床上用于治疗仔猪黄白痢，断奶猪的应激性腹泻，肥猪及母猪的腹泻作了对比试验，结果表明：微生态保健品对仔猪黄痢的治愈率为93％，对仔猪白痢的治愈率为95％，对断奶仔猪的应激性腹泻治愈率为94％，对肥猪及母猪的腹泻治愈率为100％。与氟哌酸、庆大霉素的疗效比较，差异显著（P＜0．05）；与氯霉素比较差异极显著（P＜0．01）．     

兽药临床试验质量管理规范体系的构建与应用

为加强兽药质量评价工作,切实做好兽药临床试验监督检查工作,农业农村部先后颁布《兽药临床研究质量管理规范》(农业部公告第2337号)和《兽药临床试验质量管理规范监督检查标准》及其监督检查相关要求(农业部公告第2464号).农业部第2464号公告[2]规定,自2018年1月1日起,未经我部监督检查或监督检查不合格的兽药安全...     

近红外光谱技术在兽药及兽药残留检测方面的应用进展

近红外光谱技术具有检测快速、高效、便携、无损等优点,成为近些年在检测领域里发展速度快、应用潜力大的快速检测分析技术之一,并逐渐在兽药及兽药残留领域里得到了应用研究.结合国内外相关研究进展及行业特点,对近红外光谱技术在兽药及兽药残留行业的应用进展评述,并对该技术在兽药及兽药残留检测领域中的应用前景进行分析和展望.