Extraction techniques for equine incisor and canine teeth

Extraction of equine incisor and canine teeth is a vital part of equine dentistry. Although dental pathology involving the incisor and canine teeth is less common, the practitioner should be prepared to diagnose conditions and develop a treatment plan. Depending on the pathology revealed via oral examination and intraoral radiographs, the treatment plan may include either simple (nonsurgical) or surgical extraction of an incisor or canine tooth. Technique and instrumentation refinement over the last 20 years has led to more precise extraction procedures with reduced secondary trauma to healthy tissues. As a result, incisor and canine extraction procedures are more predictable in execution and quality, with minimal complications.     

用头骨上齿隙鉴定布氏田鼠种群年龄的研究

本文在笔者前期工作的基础上,根据布氏田鼠15项生长指标的主分量分析结果,筛选出以头骨上齿隙作为划分布氏田鼠相对年龄组客观而简便实用的指标。该鼠的头骨上齿隙没有性别差异,对雌雄鼠可采用同一标准同时划分其年龄组。通过进一步分析,将其划分为五个年龄组：幼年组的上齿隙在6．49mm以下,亚成年组为6．50～7．33mm,成年一组为7．34～838mm,成年二组为8．39～9．43mm,老年组在9．44mm以上。此外,本文尚就年龄组成及其季节变化、年龄与繁殖等方面进行了分析。     

Self-limiting subepidermal bullous disease in a neonatal foal

A 1-day-old Appaloosa colt developed vesicles/bullae involving the skin of the lips and prepuce and multiple mucous membranes. Histopathology revealed subepidermal vesicles/bullae that were clear or contained variable numbers of neutrophils and erythrocytes. The separated epidermis appeared viable. The denuded dermal papillae were often disrupted by microabscesses or coated with fibrinosuppurative debris. Fragmented basement membrane components were attached to exposed dermal papillae. Immunoperoxidase staining of sections for deposition of IgG, IgM, IgA, and C3 were positive for IgG at the basement membrane and intercellular bridges. Complete recovery ensued. The characteristics of the subepidermal bullous lesions and clinical course of lesion resolution in this foal suggested a drug-induced pathogenesis. The only known drug exposure of the foal or mare was topical application of 7% iodine to the umbilicus at the time of foaling. Similar reactions to iodine administration have been reported in humans.     

Natural occurrence of neoplastic lesions in young sprague-dawley rats

It is important for the assessment of toxicological effects of chemicals to know what kinds of neoplasms naturally occur in the early life of experimental animals. In the present study, we demonstrated spontaneous neoplasms in Sprague-Dawley rats used in 4-, 13- and 26-week toxicity studies conducted at Bozo Research Center in the last decade. The tumors, which were first observed in 19-week-old animals, included anterior adenoma of the pituitary, follicular cell adenocarcinoma and C cell adenoma of the thyroids, nephroblastoma of the kidneys, basal cell tumor of the skin and malignant lymphoma. Thereafter, hemangiosarcoma of the tongue, adenocarcinoma of the submandibular glands, histiocytic sarcoma of the spleen, oligodendroglioma of the brain and adenocarcinoma and fibroadenoma of the mammary glands were detected in 32-week-old animals. The incidences of mammary adenocarcinoma and pituitary anterior adenoma were higher than those of other tumors. The present results showed that the same tumors as reported in aged rats could also develop in younger rats.     

新疆瘦肉型新品种猪血清CPK活力与肌肉性状的关系

在新疆瘦肉型新品种猪培育期间,选择三个不同品系,连续三个世代,分别测定了供试猪的ＣＰＫ（磷酸肌酸激酶）活力、背膘厚度与眼肌厚度,探讨了它们之间的关系,结果表明：各品系猪经三个世代选择,ＣＰＫ活力逐代呈上升趋势,各世代之间均差异显著（Ｐ〈０．０１）;三世代与一世代相比,平均背膘厚度减少０．５１ｃｍ,眼肌厚度增加０．５４ｃｍ,差异显著（ｐ〈０．０５,Ｐ〈０．０１）;新品种猪试验全期ＣＰＫ活力与背膘厚度     

Putative Diethylcarbamazine-induced Urticaria with Eosinophilic Dermatitis in a Dog

Résumé— Une urtricaire due à la diethylcarbamazine associée à une dermite prurigineuse a été suspectée chez un chien mâle castré croisé Retriever. L'animal présentait des lésions d'urticaire multiples qui avaient tendance à fusionner au niveau des paupières, des lèvres, les conques auriculaires et du prépuce. Les biopsies cutanées ont révélé un infiltrat périvasculaire et périannexiel intense riche en polynucléaires éosinophiles. Parfois les polynuclaires éosinophiles étaient “dégranulés” ou présentaient des formes “en flamme”. La suppression de l'administration de diethylcarbamazine a été suivie d'une disparission rapide de toutes les lésions cutanées. L'hypothèse d'une réaction immune à la diethylcarbamazine est proposée. [Vitale, C. B., Ihrke, P. J., Gross, T. L. Putative diethylcarbamazine-induced uticaria with eosinophilic dermatitis in a dog. (Probable urticaire et dermite éosinophilique induites par la diethylcarbamazine chez un chien). Resumen— Se describe el caso de un perro macho castrado, cruzado de retriever que presentaba una dermatitis pruritica con urticaria supuestamente inducida por dietilcarbamacina. El perro mostraba multiples habones, principalmente alrededor de los ojos, la boca, los pabellones auriculares y el prepucio. El estudio histológico mostró un infiltrado perivascular y perianexal, con predominancia de eosinófilos. Ocasionalmente los eosinófilos degranulaban formando “figuras en llama”. La retirada de la terapia con dietilcarbamacina fue seguida por una mejoria rápida y espectacular de todas las lesiones cutáneas. Se postula una reacción adversa a la dietilcarbamacina mediada por factores inmunológicos. [Vitale, C. B., Ihrke, P. J. and Gross, T. L. Putative diethylcarbamazine-induced urticaria with eosinophilic dermatitis in a dog (Urticaria con dermatitis eosinofilica supuestamente inducida por dietilcarbamacina en un perro). Zusammenfassung— Es wird über eine vermutlich Diethylcarbamazin-verursachte Urtikaria mit Juckreiz bei einem männlich-kastrierten Retrievermischling berichtet. Der Hund wies generalisiert multifokale Striemen auf, die dazu tendierten um Augen, Mund, Ohrmuscheln und Präputium zusammenzulaufen. Die Hautbiopsie zeigte ein starkes perivaskuläres und periadenxales Infiltrat mit vorwiegend eosinophilen Granulozyten. Gelegentlich degranulierten die Eosinophilen zu “Flammenform”. Das Absetzen von Diethylcarbamazin führte zu einer dramatischen und raschen Abheilung aller Hautveranderungen. Es wird eine immunologischvermittelte Arzneimittelreaktion auf Diethylcarbamazin vermutet. [Putative diethylcarbamazine-induced utricaria with eosinophilic dermatitis in dogs (Vermutlich Diethylcarbamazin-verursachte Urtikaria mit eosinophiler Dermatitis beim Hund). Abstract— A suspected diethylcarbamazine-induced urticarial dermatitis with associated pruritus is reported in a castrated male mixed breed retriever. The dog had generalized multifocal wheals that tended to cluster around the eyes, mouth, pinnae, and prepuce. Skin biopsy revealed an intense perivascular and periadnexal infiltrate with eosinophils predominating. On occasion, eosinophils degranulated to form “flame figures”. Withdrawal of diethylcarbamazine resulted in dramatic and rapid resolution of all skin lesions. An immunologically mediated adverse drug reaction to diethylcarbamazine is proposed.