Adjuvants et stimulants de l'immunité: propriétés immunorégulatrices du muramyl-dipeptide, des corynébactéries anaérobies et du diéthyldithiocarbamate de sodium

Several immunomodulator agents may influence the host immune system. Among them there are the adjuvants and the immunostimulant agents. In this paper, after a brief review of the mechanism of action of adjuvants, we have described the adjuvant and stimulant properties of muramyl-dipeptide, anaerobic corynebacteria and sodium diethyldithiocarbamate.     

Analogie entre les rétrovirus humains lymphotropes et les rétrovirus des grands animaux

The family Retroviridae comprises some fifty viruses in three subfamilies: Oncoviridae, Lentiviridae and Spumaviridae. A better understanding of retroviral pathobiology has resulted from the rapid developments in knowledge of the molecular biology of normal and cancerous cells as well as retroviruses. Genomic relatedness was found between two human T cell leukemia viruses and bovine leukemia virus; similarly, some relatedness appears possible between human AIDS (acquired immunodeficiency syndrome) virus and lentiviruses of large animals. Because of their genomic relatedness, retroviruses from man and animals could theoretically form recombinants during in vitro manipulation. Therefore persons who work with retroviral materials should follow established laboratory practices to control infectious agents.     

Aspects épizootiologiques des affections respiratoires porcines qui sévirent au Québec, de septembre 1980 à février 1981

Epizootiological aspects of porcine respiratory diseases which were encountered in Quebec from September 1980 until February 1981     

Facteurs influençant le profil métanologie des vaches laitières

Forty Holstein dairy cows were used to determine the effects of forage feeding system, season and stage of lactation on some blood parameters. Blood urea nitrogen was higher for cows consuming higher levels of crude protein and particularly for the ones on pasture. Hemoglobin and packed cell volume values were correlated with the level of crude protein intake and stage of lactation. Lower values of these parameters were observed with lower crude protein intake and in early lactation. Serum levels of albumin, calcium, inorganic phosphorus, sodium and potassium were not affected either by forage system, season or stage of lactation. Serum magnesium level was lower for forage system containing corn silage. Blood glucose was lower for cows in early lactation but was not affected by feeding systems during winter. Cows on pasture had higher blood glucose levels. Lower total protein concentration in blood was observed between 90 and 180 days of lactation as a result of lower gammaglobulins. Blood parameters are good indicators of nitrogen and energy nutritional status of dairy cows. However, blood mineral concentrations are not related to the level of mineral intake of animals.     

La gestion sanitaire des élevages de rongeurs utilisés en recherche biomédicale: I. La nécessité de disposer d'animaux homogènes dans leur réaction

The necessity for the disposal of homogeneous reacting animals