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1.
Evoked potentials and auditory reaction time in monkeys 总被引:1,自引:0,他引:1
Monkeys with bipolar stimulating and recording electrodes in primary auditory cortex were trained to release a key to the onset of a pure tone. Substitution of direct cortical stimulation for the pure tone resulted in a reduction of 15 milliseconds In the latency of the behavioral response. This changed latency agreed with the latency of the primary evoked potential recorded from the animals. Systematic related changes in the amplitude of the central response and in the latency of the behavioral response followed changes in the intensity and frequency of the acoustic stimulus. 相似文献
2.
COLEMAN PD 《Science (New York, N.Y.)》1959,130(3366):39-40
Responses were recorded simultaneously from a number of electrodes on the auditory cortex of one hemisphere of cats. Response amplitudes at different electrodes reached maxima and minima at different real or apparent locations of a click stimulus. 相似文献
3.
Tonotopic organization of the auditory cortex: pitch versus frequency representation 总被引:6,自引:0,他引:6
According to the place principles of the classical hearing theory, the physical entity frequency is encoded in the auditory periphery as place information (tonotopic representation), which is decoded in more central parts of the auditory system to form the subjective entity pitch. However, this relation is true only for pure-tone signals (spectral pitch); it can be quite different in the case of complex auditory stimuli (virtual pitch), thus requiring a multistage process for pitch formation. Neuromagnetic measurements showed that the tonotopic organization of the primary auditory cortex reflects the pitch rather than the frequency of the stimulus; that is, the pitch formation process must take place in subcortical regions. 相似文献
4.
Monkeys that were trained to perform auditory and visual short-term memory tasks (delayed matching-to-sample) received lesions of the auditory association cortex in the superior temporal gyrus. Although visual memory was completely unaffected by the lesions, auditory memory was severely impaired. Despite this impairment, all monkeys could discriminate sounds closer in frequency than those used in the auditory memory task. This result suggests that the superior temporal cortex plays a role in auditory processing and retention similar to the role the inferior temporal cortex plays in visual processing and retention. 相似文献
5.
Human subjects were trained by traditional methods of instrumental conditioning to change the amplitude of a late component of the auditory evoked potential with and without oscilloscopic feedback of their performance. 相似文献
6.
Changing the source and intensity of the auditory signal to six trained cats responding to meaningful auditory stimuli permits exogenous and endogenous processes in the auditory evoked potential to be separated. For short-latency exogenous processes, latency and amplitude depend on the parameters of the physical stimulus. However, the amplitude and shape of longer-latency endogenous processes are essentially independent of the location and intensity of the signal source and seem to be invariant concomitants of the significance of the signal. 相似文献
7.
Japanese macaques were trained to discriminate two forms of their coo vocalization before and after unilateral and bilateral ablation of the temporal cortex. Unilateral ablation of the left superior temporal gyrus, including auditory cortex, resulted in an initial impairment in the discrimination, but similar unilateral ablation of the right superior temporal gyrus had no effect. Bilateral temporal lesions including auditory cortex completely abolished the ability of the animals to discriminate their coos. Neither unilateral nor bilateral ablation of cortex dorsal to and sparing the auditory cortex had any effect on the discrimination. The perception of species-specific vocalizations by Japanese macaques seems to be mediated by the temporal cortex, with the left hemisphere playing a predominant role. 相似文献
8.
Sensory responsiveness of single neurons in posterior association cortex of kittens that were 7 to 50 days old was investigated. The percentage of trimodal cells (that is, cells that respond to visual, auditory, and somesthetic stimulation) increased gradually until day 50, when percentages of trimodally responsive cells approached the adult level. In the youngest kittens, cells were predominantly responsive to only visual stimulation. With maturation, responsiveness to auditory and then to somesthetic stimulation was observed in increasing percentages of cells. 相似文献
9.
To determine whether peripheral afferent pathways could be bypassed in the performance of purposive movement, a group of monkeys was trained to avoid shock by flexing a forelimb in response to an auditory stimulus. The dorsal roots of the responding limb were then sectioned. Postoperatively it was found that the affected limb could be reconditioned. 相似文献
10.
B G Wickelgren 《Science (New York, N.Y.)》1971,173(991):69-72
Many cells in the intermediate and deep gray layers of the superior colliculus of the cat respond to both auditory and visual stimuli. These cells have similar receptive fields for both modalities and are directionally selective for both modalities, requiring stimuli moving laterally away from the animal. Perhaps cells that integrate auditory and visual information participate in the control of orienting and following responses to stimuli of both modalities. 相似文献
11.
Amplitude modulation is a predominant temporal feature in many vocal signals. The leopard frog, Rana pipiens, has a class of neurons in the central auditory system that respond selectively to particular rates of amplitude modulation; these neurons can be characterized by a temporal tuning curve. Such selectivity is absent in the peripheral auditory system. This type of transformation may be fundamental in processing temporal information in the vertebrate sensory nervous system. 相似文献
12.
Hungry animals were trained to press a lever for brain stimulation. Different tones were presented concurrently with the stimulation. A second lever delivered food only during critical tone periods. Animals were able to discriminate tones presented concurrently with rewarding intracranial stimulation, and they also interrupted self-stimulation behavior to respond appropriately under other reinforcements. 相似文献
13.
Platinum or gold electrodes derivatized with an N,N'-dialkyl-4,4'-bipyridinium reagent can be used to reduce horse heart ferricytochrome c, whereas reduction doses does not occur at the "naked" electrodes. From 3 to 17.7 millimoles per liter, the reduction of ferricytochrome c is mass transport-limited at electrode potentials more negative than about -0.6 volt against a saturated calomel reference electrode. Data for the photoreduction of ferricytochrome c at derivatized p-type silicon photocathodes show directly that the rate of reduction is mass transport-limited. Use of derivatized electrodes may allow convenient manipulation and analysis of biological molecules that do not ordinarily respond at conventional electrodes. 相似文献
14.
The frequency sensitivity of the auditory nervous system of cricket frogs (Acris) varies geographically. This variation is closely matched to the spectral energy in their mating calls, thus enabling them to respond preferentially to the calls of their local dialect. 相似文献
15.
The acoustic features useful for converting auditory information into perceived objects are poorly understood. Although auditory cortex neurons have been described as being narrowly tuned and preferentially responsive to narrowband signals, naturally occurring sounds are generally wideband with unique spectral energy profiles. Through the use of parametric wideband acoustic stimuli, we found that such neurons in awake marmoset monkeys respond vigorously to wideband sounds having complex spectral shapes, preferring stimuli of either high or low spectral contrast. Low contrast-preferring neurons cannot be studied thoroughly with narrowband stimuli and have not been previously described. These findings indicate that spectral contrast reflects an important stimulus decomposition in auditory cortex and may contribute to the recognition of acoustic objects. 相似文献
16.
Intracranial self-stimulation techniques, modified for use with neuropsychiatric patients, provide data suggestive of positive and negative reinforcing properties of brief electrical stimulation to various subcortical structures of the human brain. 相似文献
17.
Monkeys were trained to respond in one way to a pair of solid objects when discrimination was by touch; in the opposite way, when by vision. These opposite habits are formed independently and can be used concurrently. The finding suggests that the neural systems responsible for tactile and visual learning are separate, even with a single pair of objects. 相似文献
18.
Although acoustic communication is not pronounced in reptiles, analysis of single auditory neurons in the medulla oblongata shows that the cochlea is a frequency analyser. Auditory neurons of the lizard Coleonyx variegatus respond to acoustic stimuli over a range of less than 0.1 to 17 kilohertz and are maximally responsive between 0.8 and 2.0 kilohertz. The frequencies to which they are most sensitive differ from neuron to neuron, ranging from 0.11 to 4 kilohertz. Some neurons have an inhibitory area which greatly overlaps the response area, so that inhibitory areas do not seem to sharply tune the response area at this level of the auditory tract. The inhibitory area is responsible for producing in some neurons a phasic response and nonmonotonic relation between sound intensity and number of impulses. The response pattern shows a tendency to change from tonic to phasic in more advanced auditory centers. This may serve to code rapid changes in the acoustic stimuli. 相似文献
19.
Electrode for sensing fluoride ion activity in solution 总被引:1,自引:0,他引:1
Electrodes constructed from single-crystal sections of rare earth fluorides respond to fluoride ion activity over more than five orders of magnitude and show a high selectivity for fluoride over other common anions. These electrodes can be used for either direct measuremnent of fluoride ion activity or detection of the end point in titration. 相似文献
20.
Cortical computational maps control auditory perception 总被引:1,自引:0,他引:1
Mustached bats orient and find insects by emitting ultrasonic pulses and analyzing the returning echoes. Neurons in the Doppler-shifted constant-frequency (DSCF) and frequency-modulated (FM-FM) areas of the auditory cortex form maps of echo frequency (target velocity) and echo delay (target range), respectively. Bats were trained to discriminate changes in echo frequency or delay, and then these areas were selectively inactivated with muscimol. Inactivation of the DSCF area disrupted frequency but not delay discriminations; inactivation of the FM-FM area disrupted delay but not frequency discriminations. Thus, focal inactivation of specific cortical maps produces specific disruptions in the perception of biosonar signals. 相似文献