疫情下生物制药专业核心课程在线教学效果调查

本文从授课教师角度,以 2018 级生物制药本科生分子生物学教学为例,对学生的学习情况进行了调查,97% 以上的学生对分子生物学在线教学感到比较满意、满意,77% 的学生对在线学习效果感到非常满意、 满意,37% 的学生知识掌握程度非常好 、好。对于课前预习课件,47% 的学生认为课前预习课件对学习的帮助很大。并介绍了在严峻形势下开展在线教学的具体实施措施,为进一步推动疫情防控期间高校在线教学提供实践经验。     

SARS-CoV-2 infection in farmed minks,associated zoonotic concerns,and importance of the One Health approach during the ongoing COVID-19 pandemic

The coronavirus disease 2019 (COVID-19) pandemic has now affected over 72.5 million people worldwide, with nearly 1.6 million deaths reported globally as of December 17, 2020. SARS-CoV-2 has been implicated to have originated from bats and pangolins, and its intermediate animal hosts are being investigated. Crossing of the species barrier and exhibition of zoonosis have been reported in SARS-CoV-2 in farm (minks), domesticated (cats and dogs), and wild animals (tigers, puma, and lions). Recently, the rapid spread of SARS-CoV-2 infection was reported in mink farms, which led to the death of a myriad minks. The clinical and pathological findings of SARS-CoV-2 infection and the rapid animal-to-animal transmission in minks are almost similar to the findings observed in patients with COVID-19. Additionally, the rapid virus transmission among minks and the associated mutations resulted in a new mink-associated variant that was identified in both minks and humans, thereby providing evidence of mink-to-human transmission of SARS-CoV-2. The new mink-associated SARS-CoV-2 variant with a possible reduced sensitivity to neutralizing antibodies poses serious risks and is expected to have a direct effect on the diagnostic techniques, therapeutics, and vaccines that are currently under development. This article highlights the current evidence of SARS-CoV-2 infection in farmed minks, and provides an understanding of the pathogenesis of COVID-19 in minks and the associated zoonotic concerns of SARS-CoV-2 transmission from minks to humans with an emphasis on appropriate mitigation measures and on the necessity of adopting the One Health approach during the COVID-19 pandemic.