小型犬脊髓穿刺技术

对 30只小型犬 (京叭 2 8只 ,杂种小型犬 2只 )进行了不同部位的脊髓穿刺。以穿刺技术的难度、造影的效果比较、脑脊液 (CSF)压力的测定和 CSF的分析结果为判断标准 ,得出如下结论 :进行 CSF收集或者测量 CSF压力时的穿刺部位 ,应选择在小脑延髓池处 ;怀疑颈部或前胸部脊髓有病变时 ,应在小脑延髓池处进行脊髓穿刺造影 ;怀疑为胸腰椎脊髓有病变时 ,脊髓造影应选择在腰椎 L 5～ 6之间 ,L 6～ 7也可以作为一种选择部位 ;穿刺过程中试验犬可以俯卧操作。另外 ,对穿刺器械的选择和使用也进行了分析     

Cervical Myelopathy Associated with Extradural Synovial Cysts in 4 Dogs

Three Mastiffs and 1 Great Dane were presented to the University of Wisconsin Veterinary Medical Teaching Hospital for cervical myelopathy based on history and neurologic examination. All dogs were males and had progressive ataxia and tetraparesis. Degenerative arthritis of the articular facet joints was noted on survey spinal radiographs. Myelography disclosed lateral axial compression of the cervical spinal cord medial to the articular facets. Extradural compressive cystic structures adjacent to articular facets were identified on magnetic resonance imaging (1 dog). High protein concentration was the most important finding on cerebrospinal fluid analysis. Dorsal laminectomies were performed in all dogs for spinal cord decompression and cyst removal. Findings on cytologic examination of the cystic fluid were consistent with synovial fluid, and histopathologic results supported the diagnosis of synovial cysts. All dogs are ambulatory and 3 are asymptomatic after surgery with a follow-up time ranging from 1 to 8 months. This is the 1st report of extradural synovial cysts in dogs, and synovial cysts should be a differential diagnosis for young giant breed dogs with cervical myelopathy.     

Treatment of Spinal Disorders in Dogs by Manipulation

Abstract— Manipulation (sudden tug or twisting movements exceeding the extreme limits of the vertebral articulations) has been applied to thirty-four dogs: nine dachshunds, nine cocker spaniels, ten pekinese and six various breeds, all with pain and stiffness in the cervical and/or thoraco-lumbar region, often accompanied by lameness, paresis, ataxia or paraplegia. Nine cases were examined by X-ray. There were no pathological findings in two, four showed medium to severe discopathia with calcifications and protrusions, and in three there was spondylo-arthrosis ossificans. By manipulation of the spine (in fourteen cases only once, in the other cases two to five times each), twenty-four were completely restored and had normal mobility and no pain. Five dogs suffered relapses several months or years later but were again restored by renewed manipulation. Four cases were free of symptoms or ameliorated at the end of the treatment, but further information is not available. One case (total paralytic paraplegia caused by a chondro-fibroma) was incurable and euthanized.     

Modified Segmental Spinal Instrumentation in Repair of Spinal Fractures and Luxations in Dogs

A modified segmental spinal stabilization technique was used in four dogs weighing 10 to 56 kg with thoracolumbar and lumbosacral spinal fractures/luxations. A Steinmann pin was bent to encircle the dorsal spinous processes and was wired together with longitudinal pins to the cranial articular facets and dorsal spinous processes in the thoracolumbar application. The central pin was omitted, and the longitudinal pins were bent at a right angle and passed through the ilial wings in the lumbosacral application. Fracture fixation and stabilization were excellent in all dogs. One broken pin was detected in one dog after 18 months. No other complications due to the spinal instrumentation were observed. Neurologic recovery was excellent in two dogs, good in one dog, and fair in one dog.     

Spinal Fixation in Dogs Using Steinmann Pins and Methylmethacrylate

Steinmann pins and methylmethacrylate were used to stabilize 17 vertebral fractures or luxations and one unstable congenital spinal deformity in 18 dogs of a wide range of ages and body weights. Of 12 dogs available for follow-up examination (4–43 months), 10 were normal or only mildly ataxic, and two were ambulatory but severely ataxic. Five dogs died or were euthanized in the early postoperative period, but none of the deaths could be attributed to the technique. Uncommon complications associated with this fixation technique were pin migration and wound infection.     

Prognostic Application of Cortical Evoked Responses in Dogs with Spinal Cord Injury

Twenty-six dogs were used in a study to determine the correlation between cortical evoked responses (CER) testing and the reversibility of paraplegia in dogs experiencing spinal cord trauma. Twenty-four dogs were client owned and presented to the University of Missouri Veterinary Teaching Hospital over a period of approximately one year. Two dogs were used as controls. Testing was done with minimal risk to the patient. Results indicate that CER testing may be valuable as an aid in the long term evaluation of whether a paraplegic patient will ever regain the ability to walk normally again.     

Partial Resection and Omentalization: A New Technique for Management of Prostatic Retention Cysts in Dogs

Objective- The purpose of this study was to determine the results of a new technique for management of prostatic retention cysts in dogs.
Study Design- A retrospective clinical study.
Animals- Eighteen client-owned dogs.
Methods- Dogs with prostatic retention cysts were treated by celiotomy and drainage of the cysts. The majority of the cyst wall was resected and residual cyst cavities were packed with omentum. All dogs were castrated.
Results- Long-term resolution of clinical signs was achieved in all dogs, with follow-up periods ranging from 6 to 42 months. Five dogs developed urinary incontinence postoperatively. This persisted in two dogs, but was well controlled with phenylpropanolamine. In the remaining dogs, the incontinence was transient and resolved within 2 months of surgery.
Conclusions- Partial cyst resection combined with omentalization and castration was a simple and effective means of managing prostatic retention cysts. The incidence of serious complications, including postoperative urinary incontinence, was low.     

Magnetic Resonance Imaging (MRI) Spinal Cord and Canal Measurements in Normal Dogs

The goal of this study was to establish Magnetic resonance imaging (MRI) reference ranges for spinal measurements in normal dogs. Forty dogs (1–10 kg, 11–20 kg, 21–30 kg, > 30 kg; 10 dogs per category) underwent spinal MRI. Measurements were performed on sagittal T2‐W images at the level of the 4th thoracic vertebra (T4), the 9th thoracic vertebra (T9) and the 3rd lumbar vertebra (L3). Spinal canal diameter (mm) ranged from 6.07 ± 0.63 (1–10 kg) to 8.27 ± 1.15 (> 30 kg) at the level of T4; 6.55 ± 0.61 (1–10 kg) to 9.04 ± 1.26 (> 30 kg) at the level of T9; and 6.80 (6.47–7.00; 1–10 kg) to 9.00 (7.90–9.73; > 30 kg) at the level of L3. There were significant differences (P < 0.05) in spinal canal diameter between groups. Mean spinal cord diameter (mm) ranged from 4.46 ± 0.51 (11–20 kg) to 4.70 ± 0.35 (1–10 kg) at the level of T4; 4.41 ± 0.50 (> 30 kg) to 4.85 ± 0.57 (1–10 kg) at the level of T9; and 4.52 ± 0.51 (> 30 kg) to 5.14 ± 0.68 (1–10 kg) at the level of L3. There were no significant differences in spinal cord diameter between groups. Spinal cord‐to‐spinal canal ratio varied significantly, ranging from 0.51 ± 0.08 (> 30 kg at L3) to 0.78 (0.69–0.80; 1–10 kg at T4) (P < 0.05). These findings are important when using MRI to evaluate patients with suspected diffuse spinal cord disease.     

Magnetic Motor Evoked Potentials for Assessing Spinal Cord Integrity in Dogs with Intervertebral Disc Disease

Magnetically elicited transcranial motor evoked potentials (MEPs) were studied in 37 dogs with type 1 intervertebral disc (IVD) disease. The waveforms were recorded from both cranial tibial muscles before and after surgery. The latencies and amplitudes obtained were compared to those of a control population (n = 14). MEPs were recordable in all dogs with mild or no neurologic deficits, but they were recordable in only 50% of ambulatory dogs that were severely ataxic. MEPs could not be elicited from nonambulatory dogs. There was a significant attenuation of the amplitudes in all clinical cases, even if the dogs demonstrated back pain alone. Significantly prolonged latencies were associated with neurologic deficits. MEPs were not good predictors of neurologic recovery. The responses obtained from the side where the disc material was found were not different from those recorded from the opposite side. MEPs were very sensitive to lesions of the spinal cord, as indicated by the significant changes in the waves in patients with mild or no neurologic deficits and in the loss of response in dogs that still demonstrated purposeful movement. Neurologic exams provided more accurate diagnoses and prognoses than did MEPs in dogs with IVD disease.     

Laser-Doppler Measurements of Spinal Cord Blood Flow Changes During Hemilaminectomy in Chondrodystrophic Dogs with Disk Extrusion

Objectives— (1) To assess spinal cord blood flow (SCBF) during surgical treatment of disk extrusion in dogs and (2) to investigate associations between SCBF, clinical signs, presurgical MRI images, and 24-hour surgical outcome.
Study Design— Cohort study.
Animals— Chondrodystrophic dogs with thoracolumbar disk extrusion (n=12).
Methods— Diagnosis was based on clinical signs and MRI findings, and confirmed at surgery. Regional SCBF was measured intraoperatively by laser-Doppler flowmetry before, immediately after surgical spinal cord decompression, and after 15 minutes of lavaging the lesion. Care was taken to ensure a standardized surgical procedure to minimize factors that could influence measurement readings.
Results— A significant increase in intraoperative SCBF was found in all dogs (Wilcoxon's signed-rank test; P =.05) immediately after spinal cord decompression and after 15 minutes. Changes in SCBF were not associated with duration of clinical signs; initial or 24-hour neurologic status; or degree of spinal cord compression assessed by MRI.
Conclusion— SCBF increases immediately after spinal cord decompression in dogs with disk herniation; however, increased SCBF was not associated with a diminished 24-hour neurologic status.
Clinical Relevance— An increase in SCBF does not appear to be either associated with the degree of spinal cord compression or of a magnitude sufficient to outweigh the benefit of surgical decompression by resulting in clinically relevant changes in 24-hour outcome.     

Extramedullary laryngeal plasmacytoma in a dog

Abstract

CASE HISTORY:?An 8-year-old, female, spayed Border Collie presented with a 3-week history of coughing, choking and haemoptysis.

CLINICAL FINDINGS:?Inspiratory stridor was evident on clinical examination. Cervical radiographs revealed a round soft-tissue mass on the dorsal aspect of the epiglottis. A laryngeal mass was evident on examination under anaesthesia, and an incisional biopsy was obtained. Histopathology revealed a dense proliferation of neoplastic round cells morphologically consistent with plasma cell origin. Immunohistochemisty results were negative for CD3 (T cell marker) and positive for CD79a (B cell marker), resulting in a diagnosis of extramedullary plasmacytoma. The patient was treated with melphalan and prednisolone; clinical signs resolved within 1 week and the mass was no longer evident on laryngoscopy after 1 month of treatment. After 6 months of chemotherapy, the laryngeal mass recurred and euthanasia was requested. There was no evidence of systemic spread on post-mortem examination.

DIAGNOSIS:?Solitary extramedullary plasmacytoma of the canine larynx.

CLINICAL RELEVANCE:?Respiratory extramedullary plasmacytomas are extremely rare with only one laryngeal and two tracheal cases previously reported. This is the first published report of a laryngeal plasmacytoma that recurred despite combination chemotherapy with melphalan and prednisolone.     

Dynamic Compression of the Cervical Spinal Cord: A Myelographic and Pathologic Investigation in Great Dane Dogs

The authors report the radiographic and pathologic findings in 10 Great Dane dogs with the wobbler syndrome. In all 10 dogs it was possible to demonstrate myelographically that there was cervical spinal cord compression at 1 or 2 sites. The spinal cord compression was mainly dynamic in nature, as degree of compression increased in extension and decreased in flexion of the neck in 8 dogs. In 1 dog with deformed vertebral bodies (G6 and C7), compression increased slightly in flexion of the neck. In another dog, compression was lateral and could only be seen in the ventrodorsal view.The macroscopic findings substantiated the radiologic findings. The cause of the spinal cord compression was in 8 dogs a decrease in the dorsoventral diameter of the orifice of the vertebral canal of 1 or 2 vertebrae in combination with deformation and elongation of 1 or several vertebral arches. In extension of the neck, the cervical spinal cord was squeezed between the anterior tip of the elongated vertebral arch and the caudodorsal rim of the body of the adjacent cranial vertebra.Histologic examination was made of the spinal cord in 5 dogs and the compressive lesions that were found could explain the neurologic signs.In the discussion, the question is raised as to why pain is not a prominent sign in dogs with the wobbler syndrome in contrast to in dogs with cervical disc protrusion. It is believed that the inflammatory foreign body reaction, triggered by the protruded calcified nucleus pulposus is the main cause of pain in the disc protrusion syndrome. In the wobbler syndrome there is no obvious inflammatory reaction in the epidural space.Finally, the possible etiologic factors oC importance for the deformation oC the cervical vertebrae in wobblers are discussed. There are indications that both overnutrition and a genetic trait for rapid growth are of importance.