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1.
Kammlott E Karthoff J Stemme K Gregory P Kamphues J 《Journal of animal physiology and animal nutrition》2005,89(3-6):105-108
Ligation of the pancreatic duct in pigs leads to severe maldigestion and malabsorption of crude nutrients. Supplementation with 24 capsules of Creon (Solvay Pharmaceuticals GmbH, Hannover, Germany) per meal led to an increased digestibility of crude nutrients. With regard to optimization of the treatment of EPI no essential improvements can be achieved by adding omeprazol or lecithin to the diet. In pancreatic duct-ligated pigs the isolated addition of omeprazol led to an increase of the pre-caecal digestibility of crude fat and organic matter. With additional enzyme substitution, the application of omeprazol did not result in an improved fat digestibility. Isolated addition of lecithin to the diet resulted in a reduced total digestibility of crude fat. Offering the diet twice a day and using a higher frequency of enzyme applications (four or six instead of only two applications) had no effects on the digestibilty of crude fat or organic matter. According to the observations in pancreatic duct-ligated pigs, the addition of missing enzymes to the diet led to the best treatment results in EPI. Administration of omeprazol or a higher feeding frequency as well as the application of enzymes in small proportion of the whole meal or dosages given consecutively over the day showed no advantages. Furthermore, the present study suggests that the addition of lecithin cannot be recommended in EPI, when given diets with butter as the predominant fat source as in human dietetics. 相似文献
2.
Kammlott E Karthoff J Stemme K Gregory P Kamphues J 《Journal of animal physiology and animal nutrition》2005,89(3-6):109-112
Ligation of pancreatic duct in pigs leads to a severe maldigestion of calcium and magnesium. Substitution of missing enzymes results in a 'normalization' of the digestibility rates of these elements. In comparison to controls the pre-caecal phosphorus digestibility decreased, but the total digestibility rates increased, after ligation of the pancreatic duct. Furthermore, the total amount of absorbed phosphorus was significantly higher in pancreatic duct ligated pigs. Further studies have to be carried out to investigate, whether phosphorus in exocrine pancreatic insufficiency is excreted with urine, as in this study the observed Ca:P-ratio in blood was in a physiological range. Without a forced renal excretion of phosphorus, consequences and risks (e.g. secondary hyperparathyroidism) of the regulation have to be considered. Regarding the elements sodium, potassium and chloride, an increased faecal excretion could be observed in pancreatic duct ligated pigs. As a substitution with enzyme products led to digestibility rates similar to those in controls, no losses of electrolytes have to be feared. Even though pancreatic juice seems to have influences on the digestibility of investigated trace elements (copper, zinc, iron and manganese), it did not lead to severe imbalances in the corresponding mineral metabolism. 相似文献
3.
Conclusions from narrative qualitative reviews on differences in total tract digestibilities between goats and sheep did not account for variability among studies. Therefore meta‐analytic techniques were used to describe the magnitude of these differences with numerical values. A unitless effect size (Hedges’ g) was applied within studies to measure differences in digestibilities of dry matter (DM; 104 comparisons), organic matter (OM; 93 comparisons), crude protein (CP; 85 comparisons), neutral detergent fibre (NDF; 74 comparisons), acid detergent fibre (ADF; 59 comparisons), cellulose (24 comparisons), hemicellulose (18 comparisons) and gross energy (GE; 29 comparisons). The absence and inability to describe independent factors which contributed to variation among studies necessitated the use of frequentist random effects and hierarchical Bayesian models in the calculation of summary statistics across studies. Digestibilities of DM, OM, CP, NDF, ADF and hemicellulose were higher (p < 0.05) in goats than sheep when all‐forage diets were fed. When concentrates were included in the diets, there were no such differences. Differences between goats and sheep in DM intake were found to be non‐significant. Differences in nutrient digestibilities of forages as sole feed implies that species‐specific values have to be used in feed formulation and feeding strategies. However, caution is needed when extrapolating results from stall‐feeding, which is how digestibility data are usually measured, to grazing conditions. 相似文献
4.
Sauer N Eklund M Roth S Rink F Jezierny D Bauer E Mosenthin R 《Journal of animal physiology and animal nutrition》2012,96(4):700-708
In previous studies, dietary nucleotides have been shown to improve performance in single-stomached animals by promoting the renewal of small intestine epithelial cells and by influencing the activity and composition of the microbial community in the digestive tract. The present experiment was carried out with 12 barrows weaned at the age of 18 days and fitted with a simple T-cannula at the distal ileum. To determine short-term effects of dietary yeast nucleotides, the piglets received a grain-soybean meal-based basal diet with or without supplementation of 1 g/kg of a dried yeast product containing free nucleotides. Dietary supplementation with yeast did not affect bacterial numbers in the ileum as well as ileal concentrations of individual short-chain fatty acids (SCFA), total SCFA and total lactic acid (p > 0.05). Moreover, there was no effect of supplemental yeast nucleotides on ileal α-amylase, leucine amino peptidase, maltase and lactase activities (p > 0.05), as well as on ileal dry matter, crude protein and crude fibre digestibilities (p > 0.05). In conclusion, short-term supplementation with dietary yeast nucleotides did not affect microbial metabolite concentrations, bacterial numbers and enzyme activities in the ileal digesta as well as ileal nutrient digestibilities of newly weaned pigs. 相似文献
5.
Clauss M Loehlein W Kienzle E Wiesner H 《Journal of animal physiology and animal nutrition》2003,87(3-4):160-173
In order to test the suitability of the horse as a nutritional model for elephants, digestibility studies were performed with six captive Asian elephants on six different dietary regimes, using the double marker method with acid detergent lignin as an internal and chromium oxide as an external digestibility marker. Elephants resembled horses in the way dietary supplements and dietary crude fibre content influenced digestibility, in calcium absorption parameters and in faecal volatile fatty acid composition. However, the absolute digestibility coefficients achieved for all nutrients are distinctively lower in elephants. This is because of much faster ingesta passage rates reported for elephants. No answer is given to why elephants do not make use of their high digestive potential theoretically provided by their immense body weight. Differences in volatile fatty acid concentrations between these captive elephants and those reported from elephants from the wild are in accord with a reported high dependence of free-ranging elephants on browse forage. 相似文献
6.
玉米-豆粕型日粮中添加复合酶对仔猪生长性能及养分消化率的影响 总被引:1,自引:0,他引:1
选用72头胎次一致,体重约20kg的健康的杜×长×大三元杂交断奶仔猪(公母各半),随机分为4组,每组3个重复,每个重复6头猪。处理Ⅰ为对照组,饲喂玉米-豆粕型基础日粮,处理Ⅱ、Ⅲ和Ⅳ为试验组,分别在基础日粮中添加0.1%,0.2%,0.3%植酸酶和纤维素酶的复合酶制剂,研究复合酶制剂对仔猪生长性能及养分消化率的影响。结果表明:试验组仔猪的平均日增重、饲料转化率以及营养物质的消化率均高于对照组,其中处理Ⅲ的效果最好,但各组的采食量差异不大。 相似文献
7.
Clauss M Polster C Kienzle E Wiesner H Baumgartner K von Houwald F Ortmann S Streich WJ Dierenfeld ES 《Journal of animal physiology and animal nutrition》2005,89(3-6):229-237
We performed intake, digestibility and ingesta passage studies in 11 Indian rhinoceroses (Rhinoceros unicornis) from four zoological institutions, using total faecal collection for the quantification of faecal output. The regularly fed zoo ration of roughage and concentrates (ration RC) and a roughage-only ration (ration R) were used; the roughage source differed between the facilities and comprised grass hay, grass silage, straw and lucerne hay. Dry matter intake ranged between 0.8 and 1.3% of body weight on ration RC and 0.5-1.2% on ration R. Digestibility coefficients achieved were similar to those reported for horses on diets of comparable composition. Endogenous losses as determined by linear regression analysis were within the range reported for horses. Measurements of faecal volatile fatty acids, faecal lactate and faecal pH also showed similarity to similar measurements in horses. The mean retention times of fluids (Co-EDTA) and particles (Cr-mordanted fibre <2 mm) in the whole gastrointestinal tract averaged 42 and 61 h, respectively, and were the longest ever recorded in a monogastric ungulate with this marker system. The results suggest that the horse is a useful model animal for designing diets for Indian rhinoceroses. Why digestive parameters are similar between these species in spite of enormous differences in body weight and retention times remains to be answered. 相似文献
8.
本试验研究了在玉米-豆粕型日粮中添加非淀粉多糖酶及α-半乳糖苷酶对生长猪饲粮干物质、粗蛋白质及能量表观消化率的影响。试验采用两个4×4拉丁方设计,选择平均体重为30kg左右的杜大长三元杂交健康去势公猪8头,共设8个处理,每个处理4个重复,每个重复1头。试验结果表明:添加非淀粉多糖酶组干物质(DM)、粗蛋白质(CP)和能量(GE)的表观消化率均有提高,且添加酶Ⅱ效果最显著;添加不同水平α-半乳糖苷酶组其干物质(DM)、粗蛋白质(CP)和能量(GE)的表观消化率也均有提高,但差异不显著(P0.05),且添加量为0.6g/kg组效果最好。 相似文献
9.
The effect of pancreatic enzyme preparation (Combizyme Forte granulate) on the growth rate of normal, sham-operated and pancreatic duct ligated growing pigs was studied in 2 trials. In the first trial 6 normal Yorkshire pigs were fed a pancreatic enzyme supplement and 6 other pigs from the same litter were fed without supplementation. The growth rate over a period of 4 weeks was not significantly greater in the supplemented group. In a second trial exocrine pancreatic insufficiency, without diabetic symptoms, was produced in 12 pigs (aged 1.5 months and weighing 14 kgs) by ligation of the main pancreatic duct. The growth rates over a period of 20 days after surgery were 240 g, 454 g and 483 g/day in ligated pigs, in ligated pigs supplemented with pancreatic enzyme and in sham-operated control pigs, respectively. The difference between the ligated groups was significant (p less than 0.01) indicating the efficiency of the pancreatic enzyme therapy. 相似文献
10.
A. Ratriyanto R. Mosenthin D. Jezierny M. Eklund 《Journal of animal physiology and animal nutrition》2010,94(6):788-796
The study was conducted to investigate the effects of graded dietary inclusion levels of betaine on ileal and total tract nutrient digestibilities and intestinal bacterial metabolites in piglets. A total of eight barrows with an average initial body weight of 7.9 kg were randomly allocated to one of the four assay diets with two pigs per treatment in four repeated measurement periods. The assay diets included a basal diet based on wheat, barley and soybean meal alone, or supplemented with a liquid betaine product at dietary levels of 1.5, 3.0, or 6.0 g betaine per kilogram diet (as‐fed). Ileal digestibilities of dry matter and neutral detergent fibre increased both quadratically and linearly, and ileal digestibility of glycine increased linearly as dietary betaine level increased (p < 0.05). Furthermore, total tract digestibility of crude protein increased quadratically (p < 0.05) and total tract digestibilities of most amino acids tended to increase quadratically (p = 0.06 to p = 0.11) with increasing dietary betaine level. Moreover, there were linear increases in the concentrations of most bacterial metabolites which were significant p < 0.05 for ileal d ‐lactic acid and for faecal diaminopimelic acid. The results demonstrate that dietary betaine supplementation stimulates bacterial fermentation of fibre in the small intestine and bacterial degradation of crude protein in the large intestine. 相似文献
11.
M. Seynaeve G. Janssens M. Hesta C. Van Nevel R. O. De Wilde 《Journal of animal physiology and animal nutrition》2000,83(1):36-48
Eight female pigs (26–61 kg) provided with a simple T-cannula about 10 cm proximal to the ileo-caecal valve, were used in two experiments to investigate the effects of Ca/P ratio, P level and supplementation with phytase (500 FTU/kg) on precaecal, post-ileal and total tract disappearances of organic matter (OM), phosphorus (P) and calcium (Ca). In experiment 1, two Ca/P ratios and two P levels were tested according to a 2 × 2 factorial arrangement within a Latin square design. In experiment 2, the diets of experiment 1 were supplemented with phytase (500 FTU/kg). There was a substantial absorption of OM, P and Ca in the post-ileal tract for all diets. Precaecal and total tract disappearances of OM were reduced by phytase addition (−4.4 and −0.8%, respectively). Supplementation with phytase resulted in an improvement of total tract and post-ileal P disappearances by 10.3 and 12.1%, respectively, without affecting precaecal P disappearance. Addition of feed phosphate resulted in a higher precaecal disappearance of P (+10.8%), resulting in a higher total tract disappearance of P (+5.9%). Addition of limestone had little effect on disappearances of OM, P and Ca, but reduced activity of supplemental phytase and had a negative influence on growth performance. Precaecal, post-ileal and total tract Ca disappearances were hardly affected by the examined dietary factors. The results might indicate that P from feed phosphate is absorbed primarily prececally and that P from phytate, liberated by microbial phytases, is dominantly absorbed post-illeally. 相似文献
12.
Caerulein administered to anaesthetized pigs by slow i.v. infusions at doses of 0.5, 1.0 and 2.0 ng kg–1min–1 for 30 min, stimulated pancreatic juice production, increased the protein content of the juice and enhanced its amylolytic, lipolytic and proteolytic activities. In a single experiment, an i.v. infusion of secretin (0.001 U kg–1min–1) lasting through the whole experimental time, provoked potentiation of the caerulein stimulatory effects on pancreatic juice production, protein content and amylolytic activity. 相似文献
13.
试验旨在通过套算法研究不同替代比例的肠膜蛋白粉对猪的有效能和营养物质表观消化率的影响。试验将24头平均体重(20.2±2.3) kg的健康去势公猪随机分为4组,每组6个重复。对照组饲喂玉米基础日粮,试验组分别是10%、20%和30%的肠膜蛋白粉替代基础日粮的试验日粮。试验期12 d,前7 d为预饲期,后5 d为粪尿收集期。结果显示,以干物质为基础,以10%、20%和30%肠膜蛋白粉替代基础日粮,试验得出的肠膜蛋白的表观代谢能分别为12.01、12.52 MJ/kg和12.10 MJ/kg(P<0.05);随着替代水平的升高,总能、有机物和中性洗涤纤维(P<0.05)的消化率降低,粗蛋白消化率先升高再降低。由此可见,生长猪对不同替代比例的各营养物质的表观消化率具有一定差异性,随着肠膜蛋白粉在基础日粮中替代比例的提高,肠膜蛋白粉的有效能值先升高再降低;当肠膜蛋白粉的比例是20%时,其原料的消化能和代谢能相对较高。 相似文献
14.
A study was conducted to determine the effects of extrusion on ruminal, post-ruminal and whole tract digestibility of flaxseed. Extrusion was performed at 155 degrees C with a residence time of 43 s. Two non-lactating Holstein cows fitted with ruminal and duodenal cannulas were used in a randomized complete block design. Results showed that extruded flaxseed had higher (P < 0.05) in situ soluble and lower (P < 0.05) slowly degradable DM and CP fractions than unheated flaxseed. Extrusion increased (P < 0.05) ruminal DM and CP degradability of flaxseed by 7 and 13%, respectively. Ruminal undegraded DM, CP and NDF were all lower (P < 0.05) for extruded flaxseed than for unheated flaxseed. Extrusion increased (P < 0.05) ruminal degradability and reduced (P < 0.05) post-ruminal availability of most amino acids of flaxseed. Whole tract digestibility of DM, CP, NDF and amino acids were higher (P < 0.05) for extruded than for unheated flaxseed. It was concluded that extrusion under the conditions used in the present experiment increases ruminal and whole tract nutrient degradabilities of flaxseed and therefore was ineffective in increasing the post-ruminal supply of amino acids from flaxseed. 相似文献
15.
Nyachoti CM Arntfield SD Guenter W Cenkowski S Opapeju FO 《Journal of animal science》2006,84(8):2150-2156
An experiment was done to determine manure output, N and P excretion, and apparent digestibilities of AA, CP, P, and DM in growing pigs fed barley-based diets containing micronized or raw peas with or without supplementation with enzyme containing primarily beta-glucanase and phytase (Biogal S+). Eight barrows (21.5 +/- 1.2 kg of initial BW) fitted with T-cannulas at the distal ileum were used in a 40-d trial and housed in metabolism cages. Pigs were assigned in a replicated 4 x 4 Latin square design to 4 experimental diets: 1) barley-raw peas control (BRP), 2) barley-micronized peas (BMP), 3) BRP plus enzyme, and 4) BMP plus enzyme (BMP+E). Pigs received 2.6 times maintenance energy requirements based on BW at the beginning of each experimental period. During each experimental period, pigs were acclimatized to their respective diets for 5 d followed by a 3-d period of total fecal and urine collection and another 2-d period of ileal digesta collection. Samples were analyzed for DM, AA (diets and digesta only), N, and P. Wet fecal output of BRP plus enzyme-fed pigs tended to be lower (P = 0.07) than the amount produced by BMP-fed pigs. The amounts of dry feces and urine produced were not different among treatments (P > 0.10). Supplementing the BRP and BMP diet with enzyme increased (P = 0.002) the daily P retained per pig. Pigs fed the enzyme-supplemented diets tended to have lower (P = 0.06) fecal P excretion and greater urinary P excretion (P = 0.001) compared with pigs fed the nonsupplemented diets, but total P excretion was not influenced by diet (P > 0.10). Pigs fed the BMP+E diet retained more (P = 0.006) N per day than pigs fed the BMP diet. However, N excretion was not influenced by dietary treatment (P > 0.10), although BMP+E-fed pigs excreted 13.2% less N in the feces compared with those fed the nonenzyme supplemented controls. Inclusion of micronized peas with or without enzyme supplementation did not affect urinary or fecal N excretion (P > 0.10) compared with the BRP. Dietary treatment had no effect (P > 0.10) on ileal or fecal DM or CP digestibilities. Apparent ileal digestibilities of AA were usually lower (P < 0.05) in the BRP diet compared with the other diets. Enzyme supplementation improved P digestibility at the ileal and fecal level. The current results indicate that utilizing micronized peas in barley-based pig grower diets enhances P retention. 相似文献
16.
17.
Wenjuan Zhang Defa Li Ling Liu Jianjun Zang Qiwu Duan Wenjun Yang Liying Zhang 《畜牧与生物技术杂志(英文版)》2013,4(1):17
The objective of this study was to investigate the effects of total dietary fiber level on nutrient digestibility and the relationship between apparent total tract digestibility of total dietary fiber, and soluble dietary fiber, insoluble dietary fiber and available energy. Sugar beet pulp was as the only fiber source. The experiment was designed as a 6 × 6 Latin square with an adaptation period of 7 d followed by a 5-d total collection of feces and urine. Feed intake tended to decrease (P =0.10) as total dietary fiber level increased. The apparent total tract digestibility of dry matter, crude protein and gross energy decreased (P <0.01) when total dietary fiber increased but the digestibility of soluble dietary fiber and insoluble dietary fiber increased (P <0.01). The digestible energy and metabolizable energy content of diets decreased (P <0.01) as the total dietary fiber increased. 相似文献
18.
Wen juan Zhang Defa Li Ling Liu Jianjun Zang Qiwu Duan Wenjun Yang Liying Zhang 《畜牧与生物技术杂志(英文版)》2013,(4):309-315
The objective of this study was to investigate the effects of total dietary fiber level on nutrient digestibility and the relationship between apparent total tract digestibility of total dietary fiber, and soluble dietary fiber, insoluble dietary fiber and available energy. Sugar beet pulp was as the only fiber source. The experiment was designed as a 6 x 6 Latin square with an adaptation period of 7 d followed by a 5-d total collection of feces and urine. Feed intake tended to decrease (P =0.] O) as total dietary fiber level increased. The apparent total tract digestibility of dry matter, crude protein and gross energy decreased (P 〈0.0]) when total dietary fiber increased but the digestibility of soluble dietary fiber and insoluble dietary fiber increased (P 〈0.01). The digestible energy and metabolizable energy content of diets decreased (P 〈0.01) as the total dietary fiber increased. 相似文献
19.
Clapper GM Grieshop CM Merchen NR Russett JC Brent JL Fahey GC 《Journal of animal science》2001,79(6):1523-1532
Plant-based protein sources are generally less variable in chemical composition than animal-based protein sources. However, relatively few data are available on the nutrient digestibilities of plant-based protein sources by companion animals. The effects of including selected soybean protein sources in dog diets on nutrient digestion at the ileum and in the total tract, as well as on fecal characteristics, were evaluated. Six protein sources were used: soybean meal (SBM), Soyafluff 200W (soy flour), Profine F (traditional aqueous-alcohol extracted soy protein concentrate [SPC 1]), Profine E (extruded SPC [SPC 2]), Soyarich I (modified molecular weight SPC [SPC 3]), and poultry meal (PM). All diets were extruded and kibbled. Test ingredients varied in CP and fat contents; however, diets were formulated to be isonitrogenous and isocaloric. Nutrient intakes were similar, except for total dietary fiber (TDF), which was lower (P < 0.01) for dogs fed the PM diet. Apparent ileal digestibilities of DM, OM, fat, and TDF were not different among treatments; however, CP digestibility at the terminal ileum was higher (P < 0.01) for diets containing soy protein sources than for PM. Total tract CP digestibility was greater (P < 0.01) for soy protein-containing diets than for PM. Apparent total tract digestibilities of DM, OM, fat, and TDF were not different among treatments. Apparent amino acid digestibilities at the terminal ileum, excluding methionine, threonine, alanine, and glycine, were higher (P < 0.01) for soy protein-containing diets than for PM. Dogs fed SPC diets had lower (P < 0.01) fecal outputs (g asis feces/g DMI) than dogs fed the SF diet, and dogs fed SBM tended (P < 0.11) to have lower fecal outputs than dogs fed the SF diet. However, dogs fed the PM diet had lower (P < 0.03) fecal outputs than dogs fed SPC-containing diets. Fecal outputs and scores reflected the TDF and nonstructural carbohydrate contents of the soy protein fraction. Soy protein sources are well utilized by the dog prior to the terminal ileum, and SPC offers a viable alternative to PM as a protein source in dry, extruded canine diets. 相似文献
20.
A technique was used to monitor continuously ruminal pH using a strip-chart recording pH meter. Ruminal pH measurements were made in four ruminal-cannulated crossbred wether lambs (ag initial weight, 42.5 kg). For l.5 h daily, lambs were given ad libitum access to 50% concentrate-50% chopped orchardgrass hay diets supplements with 0, l.5, 3.0 and 4.5% sodium bicarbonate (NaHCO3). A split-plot Latin-square design was used to evaluate NaHCO3 level and day of adaptation on the percentage of time (%T) that ruminal pH was less than 6.6, 6.2, 5.8, 5.4 and 5.0. No effect due to day of adaptation existed for ruminal pH measurements (P more than .10), while the effect of dietary NaHCO3 level was quadratic (P more than .01) for the %T that ruminal pH was less than 5.4. To evaluate the effects of NaHCO3 on nutrient digestion, the same diets were fed to eight wether lambs (avg initial weight, 38 kg) at 85% of their ad libitum intake in a replicated 4 x 4 Latin-square digestion trial. Digestibilities of dry matter (DM), organic matter, N and fiber fractions were not different due to level of NaHCO3 (P greater than .10). Ash digestibility increased with increasing levels of dietary NaHCO3 (P less than .01). Four ruminal-cannulated mature Hereford steers were also given ad libitum access to the diets in a split-plot Latin-square trial to evaluate effects of dietary NaHCO3 level on ruminal pH and in situ digestion of soybean meal N and orchardgrass DM. During incubation of the dacron bags for 3, 6, 9, 12, 24 and 36 h also increased linearly with increasing level of NaHCO3. Ruminal solid and liquid dilution rates were not affected by level of supplemental NaHCO3 (P greater than .10). The results of these trials suggest that increasing level of dietary NaHCO3 greatly increases the proportion of time ruminal pH is above critical levels for ruminal protein and dry matter digestion, but does not affect total tract nutrient digestion when 50% concentrate diets are fed. 相似文献