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Yuto SANO Kazuya MATSUDA Keisuke OSAKI Taku MIYASHO Tomonori TSUDA Hiroyuki TANIYAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(12):1617-1621
A male Thoroughbred fetus was
aborted on day 251 of pregnancy. Gross and histological examinations detected systemic
granulomatous lesions in many superficial and visceral lymph nodes and organs including
the liver, tonsils, lungs, thymus, spleen, right thyroid gland and gastrointestinal tract,
and suppurative placentitis, pyogranulomatous amnionitis and intralesional acid-fast
bacilli were also detected. An examination of the DNA base sequence of the β subunit of
RNA polymerase demonstrated that Mycobacterium avium strain 104 had
infected several organs. To the best of our knowledge, this is the first report of equine
fetal mycobacterial infection in Japan. 相似文献
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Hirohisa MEKATA Satoshi SEKIGUCHI Satoru KONNAI Yumi KIRINO Yoichiro HORII Junzo NORIMINE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(9):1115-1120
Horizontal transmission is recognized as a major infection route for bovine leukemia
virus (BLV), and cattle with high viral loads are considered to be a major infectious
source in a herd. However, a correlation between viral loads and the risk of infection has
been insufficient to use as a foundation for BLV control strategies. In this report, we
examined the epidemiology of BLV infection and the infectious source in a local area. In
2013–2014, BLV infection was investigated in 1,823 cattle from 117 farms in two adjacent
districts, Miyazaki, Japan. Seropositive samples for BLV were detected with 88 cattle and
in 14 farms. Phylogenetic analysis revealed that 94% of the isolates clustered into
genotype I and the remaining isolate into genotype III. Among genotype I, genetically
distinct strains were spread at each farm, and cattle infected with less than 3 copies/100
cells did not transmit BLV to other cattle for more than thirty months. This is the first
report of concrete data of viral load in relation to viral horizontal transmission under
the field condition. The data facilitate farmers and veterinarians understanding the
status of BLV infected cattle. This research contributes to BLV infection control and the
development of effective BLV eradication programs. 相似文献
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Reiko ABE Kyoko FUJIMOTO Yuko ENDO Katsuaki SUGIURA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(12):1826
The sales amount of antimicrobials intended for use in dairy cattle, beef cattle and broilers from 2008 to 2019 was evaluated for each antimicrobial class and administration route using dosage-based indicators. Our results revealed that the antimicrobial sales amount sold for use in dairy cattle in 2019 in terms of total weight of active ingredient, the number of defined daily doses (DDDs) (theoretical amount of biomass subjected to antimicrobial treatment in a year) and the number of treatment days (TDs) (theoretical number of days of treatment that an animal is subjected to in a year) calculated using Japanese DDD values (DDDjp values) was 36,751 kg, 8,261,848,000 kg·days and 15.5 days, respectively. Likewise, the antimicrobial sales amount sold for use in beef cattle and broilers in 2019 in terms of these metrics was 33,403 kg, 3,928,248,000 kg·days and 3.61 days, and 69,773 kg, 2,947,848,000 kg·days and 10.66 days, respectively. There was a considerable difference between the number of DDDs calculated using DDDjp values and that calculated using European DDD values (DDDvet values) for antimicrobial products sold for use in dairy and beef cattle. Our results also revealed that the sales amount of some antimicrobials, such as cephalosporins and quinolones represented larger proportions when calculated using dosage-based indicators than when calculated using the weight of active ingredient. Considering that Japanese veterinarians and farmers are more likely to conform to the Japanese dosage recommendations rather than the European ones, these results indicate the need for using dosage-based metrics, in particular metrics based on Japanese dosages rather than European dosages. 相似文献
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Masaya IGASE Kenji BABA Takako SHIMOKAWA MIYAMA Shunsuke NOGUCHI Takuya MIZUNO Masaru OKUDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(11):1507-1510
A 6-year-old spayed female Jack Russell Terrier presented with a 1-month
history of lethargy, anorexia, vomiting and weight loss. The dog was fed beef and chicken
jerky treats daily in addition to a commercial diet. Laboratory tests revealed azotemia,
hypokalemia, hyperchloremia, metabolic acidosis and glucosuria with normoglycemia. Urine
amino acid analysis showed significant amino acid loss into the urine. Thus, Fanconi
syndrome was diagnosed, and based on the case history and extensive diagnostic testing,
excessive consumption of jerky treats was strongly suspected as the cause. Glucosuria
resolved 7 days after the withdrawal of jerky treats and fluid therapy. Aminoaciduria was
substantially, but not completely, improved 3 months after diagnosis. Mild azotemia
remained, suggesting chronic renal disease. To the best of our knowledge, this is the
first reported case of Fanconi syndrome following the consumption of jerky treats in
Japan. 相似文献
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Taichi ODAGAWA Mizue INUMARU Yukita SATO Koichi MURATA Yukiko HIGA Yoshio TSUDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2022,84(10):1391
Avian malaria is a mosquito-borne disease of birds caused by avian Plasmodium spp. in worldwide scale. Some naïve birds show serious symptoms which can result in death. Surveillance of vectors and parasites are important to understand and control this disease. Although avian malaria has been found in Japan, detailed prevalence and dynamics remained understudied. We aimed to observe annual changes in the abundance of mosquitoes and the prevalence of avian Plasmodium parasites in Japan. Mosquitoes were collected using dry ice traps over a 10-year period, at a fixed research area located in Kanagawa prefecture. Collected mosquitoes were investigated for the species composition, population size and prevalence of avian Plasmodium by PCR. Mosquitoes belonging to 13 species in 7 genera were collected (n=8,965). The dominant species were Aedes (Ae.) albopictus and Culex (Cx.) pipiens group (gr.). Seven avian Plasmodium lineages, all of which were previously known, were detected from Cx. pipiens gr., Ae. albopictus, and Tripteroides bambusa. Three genetic lineages were dominant and were probably transmitted by Cx. pipiens gr. whose could be the primary vector of these parasites. Annual variations in the seasonal prevalence of mosquitoes and avian Plasmodium were revealed for the first time during recent 10 years in Japan. Namely, avian Plasmodium occurrence in the vector population peaked often in June to July and September to October when the density of the vector population was presumably high enough for the transmission of avian Plasmodium upon appearance of infected birds. 相似文献
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Kanako ISHIHARA Mieko SAITO Natsumi SHIMOKUBO Yasukazu MURAMATSU Shigeki MAETANI Yutaka TAMURA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(12):1627-1629
Veterinary staff carrying
methicillin-resistant Staphylococcus aureus(MRSA) can be a source of MRSA
infection in animals. To identify risk factors of MRSA carriage among veterinary staff,
MRSA carriage and epidemiological information (sex, career, contact with MRSA-identified
animal patients and others) were analyzed from 96 veterinarians and 70 veterinary
technicians working at 71 private veterinary clinics in Japan. Univariate analysis
determined sex (percentage of MRSA carriage, male (29.2%) vs. female (10%);
P=0.002) and career (veterinarians (22.9%) vs. veterinary technicians
(10%); P=0.030) as risk factors. Multivariable analysis revealed that sex
was independently associated with MRSA carriage (adjusted odds ratio, 3.717; 95%
confidence interval, 1.555–8.889; P=0.003). Therefore, male veterinary
staff had a higher risk of MRSA carriage than female staff. 相似文献
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Azusa SOMEYA Ryoko FUKUSHIMA Michiko YOSHIDA Yasuyuki TANAHASHI Tangmunkhong PRAPEUK Reiko IIZUKA Hiroshi HIRAMI Atsushi MATSUDA Shunichi TAKAHASHI Goro KURITA Takashi KIMURA Misuzu SEO Masayuki FUNABA Yoshii NISHINO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(8):1157-1160
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用不同剂量的口蹄疫灭活疫苗免疫3组雌性BALB/c小鼠,同时设空白对照组,每组8只。免疫后每7d采血一次,用液相阻断ELISA(LPB-ELISA)检测血清抗体水平;第28d用800LD50同源强毒攻击,攻毒后36h,每组随机选取3只BALB/c小鼠,采全血,分别用每只BALg/c小鼠全血注射12只乳鼠,每组共注射36只乳鼠,以乳鼠试验判定BALB/c小鼠的病毒血症和攻毒保护情况。结果表明,免疫组BALB/c小鼠均可产生特异性抗体,保护率分别为75.0%、63.9%、36.1%;对照组小鼠血清抗体为阴性。提示,BALB/c小鼠可以用来评价口蹄疫灭活疫苗的免疫效力。 相似文献
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Baxi MK Baxi S Clavijo A Burton KM Deregt D 《Veterinary journal (London, England : 1997)》2006,172(3):473-481
Foot-and-mouth disease virus (FMDV) is the most economically important veterinary pathogen because of its highly infectious nature and the devastating effects the virus has on the livestock industry. Rapid diagnostic methods are needed for detection and typing of FMDV serotypes and differentiation from other viruses causing vesicular diseases. We developed a microarray-based test that uses a FMD DNA chip containing 155 oligonucleotide probes, 35-45 base pair (bp) long, virus-common and serotype-specific, designed from the VP3-VP1-2A region of the genome. A set of two forward primers and one reverse primer were also designed to allow amplification of approximately 1100 bp of target sequences from this region. The amplified target was labelled with Alexa-Fluor 546 dye and applied to the FMD DNA chip. A total of 23 different FMDV strains representing all seven serotypes were detected and typed by the FMD DNA chip. Microarray technology offers a unique capability to identify multiple pathogens in a single chip. 相似文献
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Most isolates of foot-and-mouth disease virus (FMDV) display a broad host range. Since the late 1990s, the genetic lineage of PanAsia topotype FMDV serotype O has caused epidemics in the Far East, Africa, the United Kingdom, France, the Netherlands, and numerous other countries throughout Europe and Asia. In contrast, there are several FMDV isolates that exhibit a more restricted host range. A Cathay topotype isolate of FMDV serotype O from the 1997 epizootic in Taiwan (O/TAW/97) demonstrated restricted host specificity, only infecting swine. Methods used to evaluate infectivity and pathogenicity of FMDV isolates in cattle are well-documented, but there has been less progress studying transmission and pathogenicity of FMDV isolates in pigs. In previous studies designed to examine pathogenicity, various chimeric viruses derived from O/TAW/97 were intradermally inoculated in the heel bulb of pigs. Subsequent quantitative scoring of disease and evaluation of virus released into nasal secretions and blood was assessed. Here we prove the usefulness of this method in direct and contact inoculated pigs to evaluate infectivity, pathogenicity and transmission of different Asian FMDV isolates. Virus strains within the Cathay topotype were highly virulent in swine producing a synchronous disease in inoculated animals and were efficiently spread to in-contact naive pigs, while virus strains from the PanAsia topotype displayed more heterogeneous properties. 相似文献
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Kei IMURA James Kenn CHAMBERS Kazuyuki UCHIDA Shunsuke NOMURA Satoshi SUZUKI Hiroyuki NAKAYAMA Yasutsugu MIWA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(12):1667-1670
An 8-month-old common marmoset
(Callithrix jacchus) was presented with tic-like symptoms, and a
2-year-old pigmy marmoset (Callithrix pygmaea) was presented with dyspnea
and hypersalivation. Both monkeys died within a few days, and necropsies were performed.
Histopathological examinations revealed ulcerative stomatitis with epithelial cell
swelling and eosinophilic intranuclear inclusion bodies in the oral epithelium of both
cases. In the central and peripheral nervous systems, neuronal cell degeneration with
intranuclear inclusion bodies was observed. Immunohistochemical examination using
anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases. Both
animals had been kept as pets with limited exposure to the ambient environment except via
their owners. Therefore, herpes simplex virus type-1 was probably acquired from close
contact with their owners. 相似文献
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Impact of foot-and-mouth disease on pork and chicken prices in Central Luzon,Philippines 总被引:2,自引:0,他引:2
Lary Nel B. Abao Hiroichi Kono Anoma Gunarathne Rolando R. Promentilla Manolita Z. Gaerlan 《Preventive veterinary medicine》2014
Central Luzon is the number one pig-producing region in the Philippines and was affected by Foot-and-Mouth disease (FMD) in 1995. In this paper, the impact of FMD on the Central Luzon meat market from 1995 to 1999 was examined. Employing the error correction model (ECM) and historical decomposition, the impact of FMD on the Central Luzon pork and chicken meat market was quantified. The following findings were observed: (a) pig farm and pork wholesale prices dropped 11.8% and 15.7%, respectively, after the initial FMD outbreaks in January, 1995; (b) in February, 1995, chicken farm and wholesale prices declined by 21.1% and 14.2%, respectively (while chicken retail prices also went down by 10.5%); (c) the margins of pig and chicken traders were also adversely affected at some point; and (d) FMD caused changes of dynamic interdependence among prices by meat type at different levels of the meat supply chain. 相似文献
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Hisako KYAN Taketoshi TAKARA Katsuya TAIRA Takeshi OBI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(8):1303
Cats are an important host of Toxoplasma gondii from an epidemiological perspective because they are the only definitive hosts that excrete oocysts in their feces. In this study, 201 free-ranging cats in Okinawa were examined for T. gondii infection. Using the latex agglutination test, we detected antibodies against T. gondii in 26.9% (54/201) of the cats. Oocysts of T. gondii were not detected upon microscopic examination of the feces of 128 cats. T. gondii was isolated from the tissues of 9 out of 24 seropositive or pseudo-seropositive cats with a bioassay using laboratory mice. Genotyping for the GRA6 gene revealed that five and four of the isolates were type I and II, respectively. 相似文献