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1.
Takashi HASEGAWA Manabu KAWATA Mitsuharu OTA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(12):1625-1631
By using ultrasound biomicroscopy (UBM), the cross-sectional structures of the entire
iridocorneal angle (ICA) which are unable to assess with gonioscopic examination were
evaluated objectively and quantitatively in live healthy and glaucomatous dogs. The ICAs
of normotensive eyes in healthy dogs with normal open angle (NOR), a predisposition to
primary closed angle glaucoma (PCAG) (PREDIS) and suffering from unilateral PCAG (UNI), as
well as the ICAs of hypertensive eyes with acute and chronic PCAG (ACG and CRG), were
assessed. The opening of the ciliary cleft in PREDIS was smaller than that in NOR. In UNI,
the opening and area of the ciliary cleft were significantly decreased compared with those
of NOR and PREDIS. ACG had widespread structural abnormalities including marked decrease
in the ciliary cleft and scleral venous plexus, and a thinner sclera than those in
normotensive eyes, whereas the ICA collapsed in CRG with the thinnest sclera. Medical
therapy-responsive glaucomatous cases had wider ciliary cleft and scleral venous plexus
than unresponsive ones. These findings suggest that the ciliary cleft and scleral venous
plexus of the ICA are key structures contributing to not only the pathophysiology of
canine glaucoma but also the responsiveness to medical therapy in glaucomatous eyes, and
cross-sectional entire structures of the ICA should be evaluated quantitatively with UBM
when diagnosing and managing canine glaucoma. 相似文献
2.
Objective To investigate the relationship of the iridocorneal angle as it appears on ultrasound biomicroscopy (UBM) to increases in IOP post-phacoemulsification in the canine eye.
Animals studied 47 eyes of 28 dogs of various age, sex, and breed.
Methods The ciliary process and limbus were used as a reference points to measure the angle opening distance (AOD), which was set by multiplying 0.45 by the distance between the ciliary process and limbus (when measured from the ciliary process). Pressure measurements were taken at five set points: Before, immediately post-, one day post-, 1 week post-, and 1 month post-phacoemulsification.
Results A weak relationship between the AOD and the IOP one day post-phacoemulsification (Intercept: 2.83, Slope: –1.24, P -value: 0.0155) was observed. No relationship immediately post-operative (Intercept: 3.45, Slope: –1.34, P -value: 0.0651), 1 week post-phacoemulsification (Intercept: 2.31, Slope: –0.01, P -value: 0.9829), 1 month post-phacoemulsification (Intercept: 1.85, Slope: –0.49, P -value: 0.1533) was observed. The pre-operative measurements made with UBM were: Distance from limbus to ciliary process (DLCP): (Minimum: 1.152, Maximum: 2.992, Mean: 1.91, SD: 0.468); AOD (Minimum: 0.104, Maximum: 0.764, Mean: 0.40, SD: 0.172).
Conclusions The relationship between AOD as measured by UBM pre-operatively is weakly associated with IOP pressure elevations at day one post-phacoemulsification. Further study is required prospectively to establish the importance of this relationship. Initial measurements of the canine iridocorneal angle were created, suggesting a method to be used in the future to establish true canine normal measurements. 相似文献
Animals studied 47 eyes of 28 dogs of various age, sex, and breed.
Methods The ciliary process and limbus were used as a reference points to measure the angle opening distance (AOD), which was set by multiplying 0.45 by the distance between the ciliary process and limbus (when measured from the ciliary process). Pressure measurements were taken at five set points: Before, immediately post-, one day post-, 1 week post-, and 1 month post-phacoemulsification.
Results A weak relationship between the AOD and the IOP one day post-phacoemulsification (Intercept: 2.83, Slope: –1.24, P -value: 0.0155) was observed. No relationship immediately post-operative (Intercept: 3.45, Slope: –1.34, P -value: 0.0651), 1 week post-phacoemulsification (Intercept: 2.31, Slope: –0.01, P -value: 0.9829), 1 month post-phacoemulsification (Intercept: 1.85, Slope: –0.49, P -value: 0.1533) was observed. The pre-operative measurements made with UBM were: Distance from limbus to ciliary process (DLCP): (Minimum: 1.152, Maximum: 2.992, Mean: 1.91, SD: 0.468); AOD (Minimum: 0.104, Maximum: 0.764, Mean: 0.40, SD: 0.172).
Conclusions The relationship between AOD as measured by UBM pre-operatively is weakly associated with IOP pressure elevations at day one post-phacoemulsification. Further study is required prospectively to establish the importance of this relationship. Initial measurements of the canine iridocorneal angle were created, suggesting a method to be used in the future to establish true canine normal measurements. 相似文献