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龙,是中华的图腾、国人崇仰的天灵、吉祥的神。中华民族世称龙的传人,龙的身影在中华文明五千年的历史长河中无处不在。自从爱上赏石,并有幸得到龙石,使我倍感幸运。 相似文献
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根书——《虎》,纯系自然而成,其形清晰优美,其神气韵生动,根友赞日：“笔走龙蛇势劲苍,颜筋柳骨旭书狂。君为艺苑添精品,细赏方知韵味长。”众友之励,故作粗识,以得引玉之效。 相似文献
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AIM: To study the expression of MDM2 and mutant-type P53 proteins in primary hepatocellular carcinoma(HCC). METHODS: Using immunohistochemical staining method(SP),the expression of mutant-type P53 and MDM2 proteins was examined in 55 cases of HCC,23 cases of corresponding paracancerous tissues and 10 cases of normal hepatic tissues. RESULTS: The frequencies of MDM2 and P53 positive expression in HCC were 17/55(30.9%) and 23/55 (41.8%), respectively. There was both positive expression of MDM2 and mutant-type P53 in 11 cases (20%) with HCC. Expression of MDM2 showed a significantly positive correlation with expression of mutant-type P53 (r=0.310,P＜0.05). The frequencies of MDM2 and P53 positive expression in corresponding paracancerous tissues cells were 1/23 (4.3%) and 2/23(8.6%), respectively. Otherwise, there was a significant statistical difference in MDM2 and mutant-type P53 protein expression between HCC and paracancerous tissues(P＜0.05). There was not positive expression of MDM2 and mutant-type P53 in normal hepatic tissue. CONCLUSION: There is MDM2 and mutant-type P53 protein overexpression in HCC. The p53 gene inactivation resulting from MDM2 protein overexpression and/or p53 gene mutation may play an important role in hepatocarcinogenesis. 相似文献
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