斑点犬阴道肿瘤的切除1例

犬阴道肿瘤比较少见,有良性和恶性之分,诊断并不困难;在治疗方面,多采用手术切除。日前笔者通过手术切除1例阴道肿瘤。 病史及临床症状 斑点犬：12岁,16kg。主诉已有1年,犬阴门向外鼓出,时大时小,近来发现异常膨出,阴道流血,遂到站求诊。     

利用高频电刀切除犬阴道肿瘤

近些年来,母犬阴道肿瘤的发病率越来越高.阴道内肿瘤阻塞了产道,影响了犬的生长繁殖性能,严重者使母犬丧失配种和繁殖能力.对犬阴道肿瘤的治疗多采用手术的方法切除肿瘤.但由于阴道内血管特别丰富,手术中止血困难,出血多,严重影响手术进程.使用高频电刀切除肿瘤则具有止血快,出血少,缩短手术进程等优点.     

犬阴道肿瘤摘除手术

犬阴道肿瘤比较少见。虽有良性与恶性之别 ,但诊断并不困难。在治疗方面 ,目前由于种种条件所限 ,一般不管性质如何 ,多采用手术切除方法。笔者现就犬阴道肿瘤手术治疗一例介绍如下 :1　病史及临床检查拳击师犬 1岁 ,该犬阴门肿胀有二个月 ,阴道口不断向外流出淡红色液体 ,经阴     

一例母犬尿道造口术的探讨

母犬尿道造口术是分离尿道将尿道口周围组织与会阴部皮肤进行缝合或切开尿道将尿道与会阴部皮肤直接缝合。虽然母犬尿道造口术在临床上比较少见,但在治疗母犬的尿生殖前庭肿瘤、阴道肿瘤、阴道脱、阴道增生、尿道结石等疾病时,如果手术波及尿道时我们常考虑实施尿道造口。2018年6月28日,我们在淮安生物工程高等职业学校动物医院接诊一只京巴母犬,该京巴母犬在淮安市涟水县某宠物医院做过疑似阴道肿瘤切除术,术后腹围增大,有排尿动作但不见尿液排出,在会阴部找不到尿道口,我们怀疑宠物医师在做京巴母犬阴道肿瘤切除时损伤尿道且没有实施尿道造口术而导致大量尿液蓄积在膀胱内。经宠主同意,我们对病犬进行DR检查、血液常规检查、血液生化检查及血气分析,根据检查结果我们对京巴母犬实施尿道造口术同时进行子宫卵巢摘除术,经过7d的住院治疗病犬康复出院。     

奶牛阴道内壁增生梨形状恶性肿瘤的治疗

部分奶牛阴道壁口与子宫口之间的阴道内壁上会增生梨形状肿瘤 ,一般都呈恶性经过。如不能尽早发现和及时治疗 ,往往都因肿瘤变性和继发感染而死亡 ,死亡率几乎10 0 %。阴道内增生梨形状恶性肿瘤笔者一共治疗 12例 ,其中 2例用手术切除 ,另 10例全部用结扎法 ,结果用手术切除的 2例全部死亡 ;而另 10例用结扎法加中西医结合治疗 ,其中 9例治愈 ,1例死亡。手术切除时 ,如果肿瘤发生在阴道深部对做手术十分不方便 ,出血量大 ,止血困难 ,缝合也十分不便 ,实际效果不好。下面重点介绍结扎加中西医结合疗法 :1　临床症状1.1　12例病牛都是 2～ 5胎…     

犬阴道前庭肿瘤电烙疗法

阴道前庭肿瘤是一种常见的良性肿瘤,主要发生于经产母犬,犬发病初期,时不时从阴道流出少量鲜红血液,随着肿瘤组织不断增生,每天从阴道流出血液量不断增多,如果不进行手术切除,每天流血不止,而且不发情,影响繁殖,甚至危及其生命.本病前、中期体温、精神、食欲等均正常.2000年以来,我宠物保健中心诊治犬阴道前庭肿瘤34例,肿瘤大的有鸡蛋大,小的有鸽子蛋大小,质脆,经采取电烙手术治疗,治愈率达100%,且无复发,现将手术过程介绍如下:     

犬阴道前庭壁层增生的诊疗

犬阴道前庭壁层增生为犬生殖系统继肿瘤之后的第二大常见外科疾病,影响犬的繁殖,临床治疗主要以手术切除为主,当增生物较大时会造成手术难度增大,笔者在临床治疗中结合具体实际采用不同方法,取得了较好的治疗结果。     

犬外阴恶性肿瘤的诊治1例

犬的外阴或阴道肿瘤是母犬生殖器官常见肿瘤,多为犬传染性性病肿瘤TVT、纤维瘤、鳞状细胞瘤和淋巴瘤等等,分为恶性或良性。目前,对于犬的生殖器肿瘤的治疗主要以手术切除为主,辅助抗肿瘤药物治疗为辅。该病会导致犬的生长繁殖性能降低,严重的会造成母犬丧失配种和繁育能力。本文就一例6岁德国牧羊犬外阴肿瘤的诊断、治疗、病因分析进行论述。     

犬阴道肿瘤与子宫颈肿瘤的切除治疗及护理

在临床上生殖器官同时出现阴道肿瘤与子宫颈肿瘤及转移扩散的发生率较低，常见的是单独器官出现病状。作者通过手术切除治疗及护理，进行病例分析和总结，为该病的临床诊断及切除术的治疗与护理提供参考，并具有一定的指导意义。     

一例犬阴道肿瘤的诊断与治疗

一例犬阴道肿瘤疑似病例,阴道触诊有异常团块,血常规检查见白细胞数目、单核细胞绝对值、中性粒细胞数目超标,X射线检查显示残段子宫内有占位性病变,B超检查显示阴道内肿瘤阴影面积较大,进而确诊为犬阴道肿瘤。遂进行手术切除,术后达到了生理机能恢复的效果。     

Limb Sparing Using a Double Bone-Transport Technique for Treatment of a Distal Tibial Osteosarcoma in a Dog

OBJECTIVE: To evaluate the treatment of a spontaneously occurring osteosarcoma in a dog by means of tumor resection and bone regeneration of a 12-cm defect using double bone transport. STUDY DESIGN: Case report. ANIMALS OR SAMPLE POPULATION: An 11 year-old client-owned German shepherd. METHODS: After tumor resection, a preassambled Ilizarov frame was secured to the proximal tibia and to the tarso-metatarsal region. Two osteotomies were performed in the proximal metaphysis. The two bone segments were transfixed with 1.5-mm-diameter wires, each secured to a ring, and bone transport was performed until the distal segment reached the talar surface. Cisplatin was administered 14, 35, and 59 days after surgery. RESULTS: Bone regenerate was first visible radiographically 4 weeks after surgery. The frame was removed 162 days after surgery. The hock was protected with a plaster cast because the tarsal arthrodesis was not complete. The dog underwent tibiotarsal arthrodesis 201 days after osteosarcoma resection. The dog died of metastatic disease 239 days after the initial surgery. CONCLUSIONS: Even though this dog died of systemic metastases, local recurrence did not develop. Cisplatin chemotherapy did not appear to negatively affect bone regeneration. CLINICAL RELEVANCE: To our knowledge, the double transport technique has not been previously described in the veterinary literature. In this dog, this technique decreased the duration of treatment compared with a conventional single-segment transport technique.     

A Gartner duct cyst of the vagina causing dysuria and dyschezia in a Yorkshire Terrier

A 5 year-old, intact female Yorkshire terrier was referred for dysuria and dyschezia. The radiographic and ultrasound examination showed a round shaped mass caudal to the urinary bladder that contained anechoic fluid within the thin walls. During surgery, the cyst was noted to be attached to the outer wall of the vagina, not connected to the vaginal lumen. Cystic fluid was removed and the cystic wall was resected. Then the remaining cystic wall was omentalized to prevent a recurrence.Histological examination confirmed that the cyst was of Wolffian duct origin. In this case, a large Gartner duct cyst causing urological problems was diagnosed and removed by surgical resection.     

Comparison of perioperative versus postoperative intratumoral administration of cisplatin for treatment of cutaneous sarcoids and squamous cell carcinomas in horses

OBJECTIVE: To determine the benefits of reducing the interval between surgical cytoreduction and intratumoral administration of cisplatin. DESIGN: Randomized clinical study. ANIMALS: 70 horses with 89 incompletely resected T2- and T3-stage sarcoids (n = 64) and squamous cell carcinomas (25). PROCEDURE: Horses were given 4 intratumoral treatments of cisplatin at 2-week intervals. The first treatment was given at the time of, or immediately after, surgical resection for horses treated in accordance with the perioperative protocol (group 1). Horses in group 2 were treated with cisplatin after the skin healed following surgical resection in accordance with the postoperative protocol. RESULTS: A difference was not found in duration of overall local tumor control between the 2 groups. Patterns of treatment failures and interval to failure differed between the 2 groups. Length of the surgical scar was the only factor that affected prognosis; an increase in length was associated with a poorer prognosis. A detrimental effect of postoperative treatment was only found in tumors with a high tumor proliferative fraction. Local reactions were similar for the 2 treatment groups, and chronic reactions were not observed. CONCLUSIONS AND CLINICAL RELEVANCE: Intratumoral administration of cisplatin is beneficial for treatment of cutaneous tumors in horses. Tumor repopulation during the interval between surgery and intratumoral administration of cisplatin decreases treatment efficacy. These results provide evidence of rapid tumor repopulation following surgical resection without a lag period for tumors with a high proliferation index. When tumor proliferation index is not known, it may be prudent to use the perioperative protocol.     

LARYNGEAL ADENOCARCINOMA IN A DOG

Laryngeal adenocarcinoma was diagnosed in a 5-year-old golden retriever dog with no history of respiratory or pharyngeal difficulties. Radiographically the basihyoid bone was destroyed by the neoplasm, and extensive soft tissue mineralization ventral to the larynx was also present. Complete surgical resection was not possible due to diffuse involvement of the tongue and larynx. Cobalt-60 teletherapy was used for treatment of the tumor. There was no clinical evidence of tumor regrowth at approximately 12 months post treatment. This is an unusual example of primary laryngeal neoplasia due to the absence of clinical respiratory abnormalities and the aggressive destruction of the basihyoid bone.     

RADIATION INDUCED VERTEBRAL OSTEOSARCOMA FOLLOWING TREATMENT OF AN INTRADURAL EXTRAMEDULLARY SPINAL CORD TUMOR IN A DOG

A 2-year-old neutered female Rottweiler diagnosed with an intradural extramedullary spinal cord tumor at T12-T13 was successfully treated with cytoreductive surgery followed by Cobalt 60 teletherapy. The dog was euthanised 5-and-a-half years later following diagnosis of an osteosarcoma involving the L1 and L2 vertebrae. Evidence of the initial tumor was not present at necropsy. The vertebral neoplasm fulfilled all of the accepted criteria for a radiation induced tumor. It was concluded that adjunctive irradiation should be considered for treatment of intradural extramedullary tumors of young dogs when total surgical resection is not possible. Although tumor induction is a rare late effect of radiation therapy, the risk of this occurrence should be considered when irradiating young animals. Radiation induced tumors in dogs have been associated with coarse fractionation schemes, or when large intraoperative doses have been administered. A lower dose per fraction, e.g., 3 Gy/fraction or less, is advisable when irradiating young dogs or any dog in which the life expectancy is 3-5 or more years after irradiation.     

Radical surgery of bovine ocular squamous cell carcinoma (Cancer Eye): A new procedure

Bovine ocular squamous cell carcinoma is a disease manifesting classic patterns of neoplasia. Untreated animals, die by local progressive growth or metastasis of the tumor. Aside from other forms of therapy, the available literature describes only local surgical treatment of the lesions. Therefore, following procedures of head and neck cancer surgery in humans, we developed a radical surgical operation for the treatment of this disease in cattle. A block resection was designed including the primary tumor, affected bone, salivary glands and the draining lymph nodes. This method leads to a better cure rate than local surgery and would be indicated when treating valuable breeding animals or other circumstances where extended treatment is warranted.     

Equine Mandibular Fibrosarcoma in Two Horses: Clinical,Diagnostic, and Therapeutic Considerations

A 25 year old Arabian gelding (case 1) presented for a large mandibular swelling involving the caudal aspect of the left horizontal mandible and a 14 year old Quarter Horse gelding (case 2) presented for a soft tissue swelling on the labial mucosa adjacent to 304. Both horses were bright and alert on presentation. Computed tomography allowed for further characterization regarding the extent of bone penetration within the lesions. This facilitated surgical planning and resection in Case 2. Histopathology of both masses diagnosed fibrosarcomas. Case 1 was humanely euthanized due to the severity of bone involvement and the grave prognosis. Case 2 underwent a left subtotal rostral hemimandibulectomy that proved to be successful in complete resection of the fibrosarcoma with a comfortable and cosmetic post-operative outcome. Surgeries that were once deemed radical should be considered for the treatment of neoplastic masses involving the soft tissues and bony structures of the oral cavity. With the aid of computed tomography, assessment of tumor penetration into deeper tissues can be achieved, thus facilitating complete surgical excision.     

Vestibulovaginal leiomyosarcoma in a mare

A 14-year-old Quarter Horse mare presented for a mass within the vestibule and vagina resulting in external compression and incomplete occlusion at the external urethral opening with subsequent difficulty urinating. Examination revealed an approximately 15 × 10 cm lobulated mass within the vestibule and caudal vagina attached via a broad base dorsally. Histopathology of the mass identified a low-grade leiomyosarcoma. Complete resection was not possible, and surgical debulking of the mass was performed during standing sedation using a vessel-sealing and dividing device. The mare was discharged 3 days post-operatively without any complications. Recheck examinations performed at 1 month and 8 months’ post-surgery revealed excellent healing of the surgical site and no apparent tumour regrowth.     

Vaginal rhabdomyosarcoma in a dog

A 10-year-old, female, mongrel showed hemorrhage from vulva. By magnetic resonance image (MRI) and endoscopic examination, a multipapillary mass with a grape-like appearance was found around the urethral opening. Histologically, the mass consisted of variable-sized round-, spindle-to-polygonal-shaped tumor cells including many multinuclear cells. Mitotic figures were also frequently observed. In some areas, that tumor cells were loosely arranged, with intercellular myxoid components. Immunohistochemically, these tumor cells were strongly positive for vimentin and focally positive for desmin but negative for myoglobin. Thus, the case was diagnosed as a relatively poorly differentiated botryoid rhabdomyosarcoma by the macroscopic, histopathologic, and immunohistochemical identification. This is the first report of botryoid rhabdomyosarcoma developing in the vagina of a dog.     

Expression of estrogen receptor alpha and beta in the uterus and vagina of immature rats treated with 17-ethinyl estradiol

The action of estrogen on target organs has been actively studied with the discovery of estrogen receptor (ER) beta. This study was carried out to examine the expression of ERalpha and ERbeta in the uterus and the vagina of immature Sprague-Dawley rats treated with 17-ethinyl estradiol (EE). Twenty days old rats were subcutaneously treated with EE at the doses of 0 (vehicle control), 0.03, 0.3, 1.0, 3.0, and 10.0 microg/kg/day for three consecutive days. The treatment of EE at the doses of 0.3, 1.0, 3.0 and 10.0 microg/kg/day significantly increased the weights of the uterus and vagina of rats (p<0.01) and retained fluid in the uterus of rats. At the high doses of 3.0 and 10.0 microg/kg/day, the treatment of EE caused an increase in the uterine height, hypertrophy, and a decrease in the expression of ERalpha and ERbeta in the uterine luminal and glandular epithelium. The treatment of EE at the doses of 3.0 and 10.0 microg/kg/day also caused cornification and a decrease in the expression of ERalpha and ERbeta in the vaginal epithelium. These results suggest that the EE treatment decrease the expression of ERalpha and ERbeta in the uterus and vagina of immature rats and that may be associated with the morphological changes such as increase in the uterine height, hypertrophy of the uterine epithelium, and cornification of the vagina.