共查询到20条相似文献,搜索用时 15 毫秒
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R Higgins P Cayouette F Hoquet F De LaSalle 《Canadian journal of veterinary research》1980,44(2):229-231
During a period of 30 months, from January 1977 to June 1979, Leptospira agglutinins were detected in 355 (6%) of 5841 bovine sera, 52 (10.1%) of 511 porcine sera, one (5%) of 20 equine sera and one (12.5%) of eight canine sera. Bovine, porcine and equine sera reacted predominantly with L. pomona. Reactors to L. hardjo/sejroe, L. icterohaemorrhagiae and L. grippotyphosa were also detected in cattle. One porcine serum reacted with L. grippotyphosa and one canine serum with L. icterohaemorrhagiae. Al the sera originated from suspected cases of leptospirosis. 相似文献
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Long-term studies of renal function in canine leptospirosis 总被引:1,自引:0,他引:1
D G Low G W Mather D R Finco N V Anderson 《American journal of veterinary research》1967,28(124):731-739
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OBJECTIVE: To evaluate the clinical signs, results of clinical pathology and serology tests, and treatment outcome of clinical leptospirosis in 40 dogs from North Queensland. DESIGN: Retrospective study from January 1995 to August 1999. PROCEDURE: Case records were reviewed for age, breed, sex, month of submission, geographical location and presenting clinical signs in 40 dogs with titres of > or = 200 for leptospirosis by the microscopic agglutination test. A biochemistry panel and complete blood count were performed on 18 dogs. RESULTS: Canine leptospirosis occurred most frequently during the summer and autumn particularly in the 'wet' tropical coastal areas of Mackay and Cairns. Fewer cases were seen in the Atherton Tablelands and 'dry' tropics around Townsville. Young and male dogs were more commonly affected. Most cases were caused by L australis (80%) and L zanoni (15%) with individual cases of L hardjo and L copenhageni. All dogs showed a distinctive multiorgan disease pattern including renal failure and cholestatic hepatopathy. Presenting clinical signs were related to these disease syndromes and included jaundice, vomiting, lethargy, inappetence, dehydration, pyrexia, abdominal pain and diarrhoea. Just over 50% of the dogs in the present study failed to recover. Clinical biochemical changes indicative of renal failure and cholestasis were significantly less severe in dogs that recovered compared with dogs that did not survive. CONCLUSIONS: Clinical pathology testing should be performed on all dogs presented for illness in the endemic areas so as to help make a presumptive diagnosis and assist in determining the prognosis as soon as possible. The presumptive diagnosis should be confirmed serologically. 相似文献
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Serodiagnosis of canine leptospirosis by solid-phase enzyme-linked immunosorbent assay 总被引:3,自引:0,他引:3
E G Hartman M van Houten J A van der Donk J F Frik 《Veterinary immunology and immunopathology》1984,7(1):33-42
An enzyme-linked immunosorbent assay (ELISA) to detect antibodies to Leptospira interrogans serotype canicola in dogs was developed and evaluated. Comparison of the ELISA with the microscopic agglutination test (MAT) showed that, during the first two weeks after an experimental infection with serotype canicola, the ELISA detected antibody at higher dilutions than the MAT. After the second week post-infection both tests detected antibody at almost equal titres (r = 0.89). The outer envelope (OE) antigen of serotypes icterohaemorrhagiae, copenhageni and canicola was fairly serotype-specific, whereas the pellet (P) antigen showed more cross-reactivity. Both OE and P antigen of Leptospira biflexa strain Patoc I could be used as cross-reacting antigen in the ELISA. Compared to the MAT, the ELISA has some technical advantages. It is suggested that the ELISA would be useful as a screening test. 相似文献
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Raghavan R Brenner K Higgins J Van der Merwe D Harkin KR 《Preventive veterinary medicine》2011,101(3-4):241-249
Associations of land cover/land use variables and the presence of dogs in urban vs. rural address locations were evaluated retrospectively as potential risk factors for canine leptospirosis in Kansas and Nebraska using Geographic Information Systems (GIS). The sample included 94 dogs positive for leptospirosis predominantly based on a positive polymerase chain reaction test for leptospires in urine, isolation of leptospires on urine culture, a single reciprocal serum titer of 12,800 or greater, or a four-fold rise in reciprocal serum titers over a 2-4 weeks period; and 185 dogs negative for leptospirosis based on a negative polymerase chain reaction test and reciprocal serum titers less than 400. Land cover features from 2001 National Land Cover Dataset and 2001 Kansas Gap Analysis Program datasets around geocoded addresses of case/control locations were extracted using 2500m buffers, and the presence of dogs' address locations within urban vs. rural areas were estimated in GIS. Multivariate logistic models were used to determine the risk of different land cover variables and address locations to dogs. Medium intensity urban areas (OR=1.805, 95% C.I.=1.396, 2.334), urban areas in general (OR=2.021, 95% C.I.=1.360, 3.003), and having urban address locations (OR=3.732, 95% C.I.=1.935, 7.196 entire study region), were significant risk factors for canine leptospirosis. Dogs regardless of age, sex and breed that live in urban areas are at higher risk of leptospirosis and vaccination should be considered. 相似文献
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S J Chernesky 《Canadian journal of veterinary research》1970,34(1):102-104
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Zwijnenberg RJ Smythe LD Symonds MI Dohnt MF Toribio JA 《Australian veterinary journal》2008,86(8):317-323
OBJECTIVE: To measure the prevalence of canine leptospirosis in Queensland and to detect infection, if present, in New South Wales, Victoria, South Australia, Western Australia and the Northern Territory by measuring the serological titres of dogs held in animal shelters. PROCEDURE: Samples were collected through stratified sampling from multiple dog shelters in Queensland and New South Wales, and from one dog shelter located in close proximity to a major urban area in Victoria, South Australia, the Northern Territory and Western Australia. All samples were analysed using the microscopic agglutination test at the WHO/FAO/OIE Collaborating Centre for Reference & Research on Leptospirosis, Queensland Health Scientific Services in Brisbane, Queensland. RESULTS: Of a total of 956 samples submitted, 18 (1.9%) had positive leptospirosis titres. True prevalence measured in Queensland was estimated to be 2.5%, and the true prevalence in New South Wales, Victoria, South Australia, Western Australia and the Northern Territory was estimated to be 2.3%, 2.8%, 0%, 1% and 1.1% respectively. An association was found between seropositive status and female dogs (odds ratio (OR) 1.92) and seropositive status and the age group 1 to < 3 years (OR 1.41). Although 11 different serovars were detected, Leptospira interrogans serovar Copenhageni was the most prevalent and was found in 4 of the 18 positive dogs as a single infection. CONCLUSION: Serological evidence of canine leptospirosis in five states in mainland Australia indicates that the disease is more broadly distributed than previously thought. 相似文献