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1.
The human malarial parasite Plasmodium falciparum can produce surface protrusions (knobs) on infected erythrocytes; however, long-term culturing of the parasite results in the appearance of knobless cells. In this study it was found that a knob-producing clone lost the ability to produce knobs in vitro. Furthermore, a clone not producing knobs derived from the knob-producing clone regained the capacity to produce knobby cells in vitro. Certain parasite proteins were associated with the knobby phenotype but not with the knobless type. These results indicate that the parasites change in vitro in a spontaneous and reversible manner independent of immunological selection. 相似文献
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Antigens that bind to erythrocytes were identified in the supernatant fluids of a cultured human malaria parasite (Plasmodium falciparum). A 175-kilodalton (175K) antigen bound only to erythrocytes susceptible to invasion. The 175K antigen from the Camp or the FCR-3 strain also bound to merozoites. However, the antigen did not bind to merozoites when merozoites and supernatant antigens were from different strains unless proteinase inhibitors were present. Moreover, erythrocytes coated with supernatant antigens from the Camp or FCR-3 strain were invaded normally by merozoites of the homologous strain but were partially resistant to invasion by merozoites of the heterologous strain. The 175K antigen may be a receptor acting as a "bridge" between erythrocytes and merozoites. 相似文献
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对自然发病的7例传染性法氏囊病鸡红细胞上C_(3b)受体的变化进行了检测,,并与10例健康鸡进行比较,发现患病鸡红纲胞上C_(3b)受体明显低于健康鸡,而红细胞上免疫复合物,两者相比变化甚微,这一结果进一步说明传染性法氏囊病毒主要侵害鸡的免疫系统,检测红细胞上C_(3b)受体的变化,亦可作为诊断该病的手段之一。 相似文献
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Hemoglobins A and A2 in New World primates: comparative variation and its evolutionary implications 总被引:3,自引:0,他引:3
S H Boyer E F Crosby T F Thurmon A N Noyes G F Fuller S E Leslie M K Shepard C N Herndon 《Science (New York, N.Y.)》1969,166(911):1428-1431
Hemoglobin A(2) (alpha(2)delta(2)) in New World primates represents about 1/160 to 1/16 of total hemoglobin and, by virtue of this low proportion, is presumed to be functionally unimportant. Nonetheless, A(2) exhibits genetic polymorphism by electrophoresis in three out of five genera, whereas the major component, hemoglobin A (alpha(2)beta(2)), is electrophoretically invariant. Moreover, in four genera, including man, the evolutionary accumulation of mutations has been greater in delta than in beta Such findings suggest that both polymorphism and evolutionary changes can accrue to an effectively functionless and thus selectively nearly netutral gene. 相似文献
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Hemoglobins in sheep: multiple differences in amino acid sequences of three beta-chains and possible origins 总被引:6,自引:0,他引:6
S H Boyer P Hathaway F Pascasio C Orton J Bordley M A Naughton 《Science (New York, N.Y.)》1966,153(743):1539-1543
Among the three adult sheep hemoglobins (A, B, and C), two (A and B) are reportedly products of alleles. The beta-chains of A and B differ by at least seven scattered amino acid residues whereas the beta-sequence of C differs from A by at least 16 residues and from B by at least 21 residues. These changes suggest that the origin of C-beta antedated the divergence of A and B. Five shared differences between A-beta and C-beta with respect to B-beta can be interpreted as the result of selective advantage in favor of B. A complex of additional mechanisms has possibly been involved in maintaining the A-B- C porymorphism. 相似文献
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多层C/S系统构架的设计与实现 总被引:1,自引:0,他引:1
C/S系统结构是一种常见的软件体系结构,在客户群体相对固定的情况下使用C/S结构的系统要比使用B/S结构更加安全和高效。本研究以Visual studio.net为开发平台,在解决进程通信方面使用了微软提供的.net remoting,在具体层次结构的设计上采用面向对象的设计原则设计了一个易于开发和维护的C/S系统构架。 相似文献
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针对当前现行的学生评教中存在的问题,介绍了基于B/S与C/S模式相结合的学生评教系统,详细阐述了系统开发的相关技术和学生评教调查表的设计,并指出了将要进一步研究的问题。 相似文献
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W Sacks 《Science (New York, N.Y.)》1967,158(800):498-499
Mutarotase was found in lysed human erythrocytes and in hemoglobin. The enzyme was partially purified by treatment with ethanol and chloroform at -15 degrees C. It was nondialyzable and heat sensitive, and was inhibited by D-galactose, L-arabinose, D-ribose, D-xylose, and D-arabinose. 相似文献
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基于C/S与B/S结合模式的农业专家信息服务平台设计研究 总被引:1,自引:0,他引:1
研究通过应用软件工程思想,采用C/S和B/S相结合的体系结构,建立了农业专家信息服务平台,实现了专家实时咨询、自主学习、提问答疑、专家评价等功能。本研究具有一定的实用价值,对提升农业信息服务的水平和效果有重要的借鉴意义。 相似文献
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水稻两用核不育系C815S所配组合杂种优势分析 总被引:15,自引:2,他引:15
以C815S等6个不育系与同一父本配组,用C815S为母本与不同的恢复系测交,分别用培两优288,两优培九作对照,观察其F1的产量、抗性、生育期、米质等性状优势,并对C815S所配组合几个主要农艺性状进行了相关分析。结果表明:6个同父不同母本组合中C815S/288产量的对照优势为15.31%;C815S为母本所配组合中产量对照优势的最大值为33.33%,两者均达到了极显著水平,表明C815S配合力好;C815S所配组合产量平均的对照优势是5.63%,表明C815S的一般配合力很好;C815S所配组合单位面积上有效穗数、每穗实粒数、结实率、千粒重与产量呈正相关,且与千粒重达到了显著水平,而每穗总粒数与产量表现出较小的负相关,有效穗与株高呈显著负相关. 相似文献
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利用Client/Server和Browser/Server两种模式建立了一套混合模式的行之有效的人事办公综合信息系统,不仅面向人事管理者和领导,而且要面向所有的教职员工、面向所有网站登陆及浏览者。根据权限的不同、需求的不同,所能接触到的内容各不相同,达到既方便单位的人事管理,又能满足教职工信息共享要求的目的。 相似文献
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从当前全国林地监督数据在管理方面存在的问题出发,以解决实际应用需求为目的,以软件工程核心思想为指导,综合.NET平台与C#语言、水晶报表技术等多种现代信息技术实现的一套面向多级用户的数字化征占用林地监督数据管理系统,为实现工作模式转变和提高工作效率和决策能力提供了解决方案. 相似文献
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Zinc protoporphyrin in the erythrocytes of patients with lead intoxication and iron deficiency anemia 总被引:11,自引:0,他引:11
The fluorescent porphyrin in the erythrocytes of patients with lead intoxication or with iron deficiency anemia is zinc protoporphyrin that is bound to globin moieties, probably at heme binding sites. 相似文献
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Sassone-Corsi P 《Science (New York, N.Y.)》2002,296(5576):2176-2178
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孙香花 《山西农业大学学报(自然科学版)》2007,27(1):90-92
讨论基于C/S生产者和消费者可以网上远程采集多种农业经济信息的实现技术,据此采用ASP.NET、SQL Server、IIS等开发平台,建立了一个用于涪陵农业经济信息的系统。 相似文献