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1.
Maximal urethral closure pressure, functional profile length, and number of respiratory peaks on the resting urethral pressure profile, expressed as a percentage of those occurring on the bladder pressure recording, were compared at catheter withdrawal speeds of 1 and 3 mm/s in 30 anesthetized bitches. Significant (P less than 0.001) differences were found in maximal urethral closure pressure and percentage of transmission of respiratory peaks between the 2 speeds. Significant difference was not detected in functional profile length. 相似文献
2.
Rawlings CA Mahaffey MB Chernosky A Huzella L 《American journal of veterinary research》2000,61(11):1353-1357
OBJECTIVE: To characterize urodynamic function and anatomy before and after colposuspension in anesthetized female Beagles. ANIMALS: 12 adult female Beagles. PROCEDURE; During general anesthesia (thiopental sodium induction and halothane maintenance), urethral pressure profiles, leak point pressure measurements with a 50-ml bladder volume, positive contrast cystograms, and retrograde vaginourethrocystograms were performed. A caudal midline laparotomy was used to perform colposuspension. Urodynamic and radiographic studies were repeated after surgery. RESULTS: Leak point pressures were increased (120 to 168.9 cm H2O), and maximum urethral closure pressures decreased (43.7 to 19.3 cm H2O ) after colposuspension. The urethra and bladder were moved cranially; the external urethral orifice was positioned closer to the pelvic cavity, and the neck of the bladder was positioned more cranially into the abdomen. Length of the urethra, as measured by use of vaginourethrocystograms, was increased by 3%. As measured by use of urethral pressure profiles, total profile length was increased by 19.9%, and functional profile length was increased by 19.2%. CONCLUSIONS AND CLINICAL RELEVANCE: Increased leak-point pressure correlated with the expected clinical improvement attributable to colposuspension. Increased exposure of the urethra to abdominal and pelvic cavity pressures may be the mechanism by which incontinent dogs become continent after colposuspension. Results of the leak-point pressure test may correlate with clinical behavior before and after colposuspension for treatment of incontinence. 相似文献
3.
P. E. Holt 《The Journal of small animal practice》1990,31(9):431-436
Simultaneous urethral pressure profilometry using an 8FG polyurethane microtip transducer catheter in the bitch is subject to considerable variation, Marked differences occur in the parameters normally measured due to the orientation of the transducers and patient position. It has been suggested that a softer catheter may result in less variation. In this study, a comparison was made between 8FG polyurethane and silicone rubber microtip transducer catheters in 35 bitches. There were significant variations in both maximum urethral closure pressure and functional profile length due to catheter type (P < 0–001). Resting intravesical pressure varied with the recording transducer (P < 0–001) and there was a significant interaction between catheter type and recording transducer (P < 0–001). Radiographic measurements on 15 bitches suggested that variations in recorded intravesical pressure were probably related to the location of the transducers of the two catheters within the bladder. It is concluded that the use of a softer catheter material alone is insufficient to eliminate variations resulting from the orientation of the recording sensors within the urethra. 相似文献
4.
The position adopted by 50 recumbent dogs was recorded while they were sleeping or resting; the commonest orientation of their hindquarters was right lateral recumbency. The intravesical pressure in the urinary bladder of 24 anaesthetised bitches lying in right lateral recumbency was compared with the intravesical pressure recorded when the same bitches were supported in a standing position. The intravesical pressure was significantly higher when the bitches were in right lateral recumbency (P less than 0.001) and the difference was unaffected by whether they were continent or not, and had no significant correlation with bodyweight. These findings help to explain why bitches with an incompetent urethral sphincter mechanism tend to leak predominantly when they are recumbent. 相似文献
5.
The conformation of the urethra, the position of the bladder neck and the distance between the external urethral orifice and the cranial pubic brim were compared in 30 continent and 30 incontinent bitches with incompetence of the urethral sphincter mechanism, using the measurements made from vagino-urethrograms. The bladder neck was significantly (P less than 0.001) further caudal in incontinent dogs than in continent dogs. Its position was not affected by neutering and could not be explained by the degree of urethral curvature. The distance from the external urethral orifice to the cranial pubic brim was correlated (P less than 0.001) with bodyweight but was not significantly different in the continent and incontinent bitches. In neutered animals, the distance between the cranial pubic brim and the external urethral orifice was significantly (P less than 0.05) shorter than in entire animals. 相似文献
6.
P E Holt 《Research in veterinary science》1989,47(3):346-349
A comparison was made between urethral pressure profiles obtained using a single sensor and 'subtracted' urethral pressure profiles resulting from double sensor recordings in 50 bitches. There were small but significant differences in the functional profile lengths and maximum urethral closure pressures between the two types of recording. The differences were partially explained by a significant fall in the intravesical pressure recorded during profilometry and variations due to respiration. The profiles from single and double sensor recording were of equal significance in the diagnosis of sphincter mechanism incompetence. 相似文献
7.
R. N. White 《The Journal of small animal practice》2001,42(10):481-486
Urethropexy was performed on 100 bitches for the management of urethral sphincter mechanism incompetence (SMI). The dogs ranged in age from 12 months to nine years (mean 4.5 years). Diagnosis of the condition was based upon clinical, laboratory and contrast radiographic examinations, and clinical response to medical management. In all bitches, incontinence developed in the adult individual and in the majority (89 bitches) after spaying. Radiographic findings were unremarkable in 22 bitches, apart from the presence of an intrapelvic bladder neck. Follow-up periods ranged from 12 months to seven years (mean 2.9 years). Fifty-six bitches were completely cured by surgery, 27 became less incontinent and 17 either failed to respond (nine animals) or showed an initial improvement in urinary function, but then relapsed (eight animals). Nine of these 17 animals underwent a second urethropexy procedure, resulting in a cure in six and an improvement in three cases (follow-up 12 to 41 months, mean 22.2 months). A deterioration in the response rate was observed over time. Postoperative complications were seen in 21 bitches and included an increased frequency of micturition (14 bitches), dysuria (six bitches) and anuria (three bitches). 相似文献
8.
P E Holt 《Research in veterinary science》1989,47(1):110-116
The technique of 'simultaneous' urethral pressure profilometry in the bitch is described. Four consecutive recordings were made from each of 100 bitches. From each recording, the maximum urethral closure pressure and functional profile length were measured and assessed for reproducibility. Analyses of variance revealed no significant differences (P greater than 0.2) between the measurements of functional profile length (means: 3.84, 3.84, 3.83, 3.80 cm; standard error of the differences: 0.037) but there were significant variations (P less than 0.001) in maximum urethral closure pressure (means of square roots: 2.26, 2.18, 2.12, 2.08 cm water; standard error of the differences: 0.042). Overall, there was a significant dependence of maximum urethral closure pressure on the measurement order (P less than 0.001). Thus, while functional profile length is a highly reproducible parameter, maximum urethral closure pressure is subject to significant variation. 相似文献
9.
P E Holt 《Research in veterinary science》1985,39(3):364-372
The urethral length, bladder neck position and presence of vestibulovaginal stenosis were recorded in 42 continent bitches and 57 incontinent bitches diagnosed as having sphincter mechanism incompetence. Incontinent animals had significantly shorter urethras and tended to have intrapelvic rather than intraabdominal bladder necks. There was no statistical difference in the incidence of vestibulovaginal stenosis between continent and incontinent bitches. 相似文献
10.
The urodynamic changes in 10 bitches up to 18 months after they had undergone ovariectomy were investigated. There were significant decreases in the maximum urethral closure pressure, the functional urethral length and the total integrated pressure profile 18 months after spaying, resulting in a caudal shift of the urethral profile, and a deterioration of urethral closure function. Each urethral pressure profile was divided into three equal sections; the mean cranial and middle integrated pressure decreased significantly and consistently over the 18-month observation period whereas the caudal integrated pressure increased. 相似文献
11.
Claeys S Rustichelli F Noël S Hamaide A 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(5):501-505
The objective of this retrospective study was to determine the efficacy of a single daily oral dose of phenylpropanolamine (PPA) in the treatment of urethral sphincter mechanism incompetence (USMI) in bitches. Nine bitches diagnosed with USMI were treated with a single daily dose [1.5 mg/kg body weight (BW)] of PPA for at least 1 month. Urethral pressure profiles (UPP) were performed in 7 dogs before treatment and repeated in 4 of them after treatment. Treatment with PPA resulted in long-term continence in 8/9 bitches. One dog did not respond to PPA and was treated surgically later. Recheck UPPs showed a significant increase in maximal urethral closure pressure in the 4 bitches after treatment with PPA compared to before treatment. In conclusion, long-term continence can be achieved in bitches affected with USMI after administration of a single daily dose of PPA (1.5 mg/kg BW). 相似文献
12.
Between 1995 and 1999, urethral sphincter mechanism incompetence was diagnosed in 11 bitches. They had been treated with phenylpropanolamine hydrochloride at the recommended dose rate, but had shown no response or had become refractory to treatment. They were treated with phenylpropanolamine hydrochloride in a sustained-release formulation combined with diphenylpyraline hydrochloride. The urinary incontinence resolved fully in six of the bitches, two of which remained continent after the treatment was withdrawn; two showed a marked improvement on daily treatment, but the other three bitches failed to respond and underwent colposuspension. 相似文献
13.
U.Th. WEBER DrMedVet Diplomate ECVS S. ARNOLD DrMedVet M. HUBLER DMV J.R. KUPPER DrMedVet 《Veterinary surgery : VS》1997,26(1):51-56
A modified technique for fixation of the deferent ducts to the abdominal wall as a therapy for urinary incontinence caused by urethral sphincter mechanism incompetence (USMI) in male dogs is described, and the results in seven dogs are reported. The goal of this treatment was to achieve an effect similar to colposuspension in female dogs with USMI. An increase in urethral length of an average of 28 mm was obtained (range, 5 to 50 mm, measured radiographically). Preoperatively, the neck of the bladder was located intrapelvically in five of seven dogs. Postoperatively, the neck of the bladder was located intra-abdominally, near the caudo-ventral abdominal wall, in all dogs. After a follow-up period of 12 to 49 months, the response to surgery, based on lack of or decrease of incontinence, was excellent in three dogs, good in another three, and poor in one dog. 相似文献
14.
RAFAEL F. NICKEL DVM Dr. Med. Vet. Diplomate ECVS URSEL WIEGAND DVM Dr. Med. Vet. W.E. VAN DEN BROM PhD 《Veterinary surgery : VS》1998,27(2):94-104
Objective —To evaluate a sling procedure using a polyester ribbon passed through the obturator foramen, around the urethra, and fixed outside the pelvis for the treatment of female dogs with refractory urethral sphincter mechanism incompetence (USMI). Animals —26 female dogs with USMI that had not improved with medical management. Methods—All dogs underwent a transpelvic sling procedure, and in 13, with a radiographic diagnosis of a pelvic bladder, additional colposuspension was performed. Multichannel urethral pressure profilometry (UPP) and diuresis cystourethrometry (UCM) were performed in all dogs before and in seven dogs 2 to 14 months after surgery. Long-term results of surgery and medical therapy were determined. Results — 13 dogs (50%), 6 of these without additional colposuspension, were continent after surgery and remained continent during a follow-up period of 12 to 36 months (mean, 19 months). Seven, three of which had colposuspension, had improved markedly. Four of these dogs became continent with additional medical therapy. Five dogs did not improve, and three of these were eventually euthanatized. In one dog, the sling was removed after 5 days because of persistent stranguria. Surgery and medical therapy together resulted in continence in 17 dogs (65%) during a follow-up period of 6 to 36 months (mean, 22 months). Postoperative dysuria or stranguria occurred in six dogs, and four of these underwent a colposuspension procedure. Two dogs developed a fistula, 2 and 3 years after surgery. Preoperatively, decreased urethral resistance was suggested by the findings of UPP and UCM in 25 dogs, and an abnormally high compliance was found in 3, detrusor instability in 2, and a low threshold pressure in 1 dog. There was no apparent correlation between these findings and the outcome of surgery. Urethral closure pressures measured after surgery were significantly increased but were still lower than the normal range in all dogs with persistent or recurrent incontinence. Conclusions —A transpelvic sling procedure, with or without additional colposuspension, can be useful in the management of dogs with refractory urinary incontinence. The procedure is not beneficial if it does not increase urethral pressure close to, or within, the normal range. 相似文献
15.
Thirteen healthy male dogs and 11 healthy female dogs were subjected to urodynamic assessment, using a simultaneous urethral pressure profile and urethral sphincter electromyogram (EMG). The study was done on the dogs in the nonsedated state and after xylazine sedation. Results showed a significant decrease in maximal urethral closure pressures in dogs of both sexes after they were given xylazine (from 79.79 cm of H2O to 23.00 cm of H2O in female dogs, and from 99.77 cm of H2O to 41.77 cm of H2O in male dogs). There was a significant reduction in EMG activities in dogs of both sexes after they were given xylazine. There was also little variability in measurements made on the same dog on consecutive days. Simultaneous intravesicular pressure and urethral pressure monitoring indicated that the effect of bladder distention on the urethral pressure profile was minimal and that there were no spontaneous detrusor contractions. This study indicates that xylazine produced a significant artifact in the simultaneous urethral pressure profile/EMG. 相似文献
16.
OBJECTIVES: The incidence of urinary incontinence due to urethral sphincter mechanism incompetence (USMI) in male dogs is relatively rare compared with the incidence in bitches, but the medical management of USMI in male dogs is less rewarding than in bitches. Attempts have been made to manage this condition surgically using either urethral bulking agents such as Teflon or by relocating the intrapelvic bladder neck to an intra-abdominal position by vas deferentopexy. This paper reports the response to prostatopexy in male dogs with USMI. METHODS: The response to prostatopexy was determined in nine severely incontinent male dogs with USMI that were followed up for periods ranging from 10 months to five years (mean 2.3 years). RESULTS: One dog was cured, four were improved, and no improvement in the frequency or degree of urinary incontinence occurred in the remaining four animals. No complications were seen in any of the dogs. CLINICAL SIGNIFICANCE: Prostatopexy may provide a further method of treating male dogs with USMI that do not respond to medical therapy. 相似文献
17.
Urethral sphincter mechanism incompetence in the male dog: importance of bladder neck position, proximal urethral length and castration 总被引:1,自引:0,他引:1
S. C. Power K. E. Eggleton A. J. Aaron P. E. Holt P. J. Cripps 《The Journal of small animal practice》1998,39(2):69-72
The radiographs of 37 incontinent adult male dogs with urethral sphincter mechanism incompetence were compared with those of 28 control dogs to determine if, as in the bitch, differences in bladder neck position and urethral length were implicated in the pathophysiology of urethral sphincter mechanism incompetence. Bladder neck position was significantly different; compared with continent dogs, incontinent animals were significantly more likely (P<0.005) to have intrapelvic than intra-abdominal bladder necks. However, after allowing for the influence of body size, and unlike the situation in the bitch, there was no significant difference in proximal urethral length between the two groups. Bladder neck position was significantly related to prostate size (P<0.001) and it is suggested that this is one reason why castrated male dogs are more prone to urethral sphincter mechanism incompetence than entire animals. A logistic regression analysis revealed that both bladder neck position and castration status were significant risk factors for incontinence and that they appeared to be acting independently of each other. 相似文献
18.
A technique was developed for recording urethral pressure profiles (UPP) in mares. Profiles were obtained from 12 clinically normal mares and from 3 mares with urinary incontinence. Variables measured on the profile included intravesicular pressure and maximal urethral closure pressure. The mean maximal urethral closure pressure of the incontinent mares was significantly less (P less than or equal to 0.001) than that of the normal mares. The technique is simple and reliable for objectively evaluating urethral pressures in mares. 相似文献
19.
'Simultaneous' urethral pressure profilometry: Comparisons between continent and incontinent bitches
P. E. HOLT 《The Journal of small animal practice》1988,29(12):761-769
‘Simultaneous’ urethral pressure profilometry using microtip pressure transducer catheters was evaluated as an aid to the diagnosis of urethral sphincter mechanism incompetence by means of comparisons between 50 continent and 50 incontinent anaesthetised bitches. Highly significant differences were detected and the technique was found to have considerable potential as a diagnostic aid. 相似文献
20.
BRUNO J. MASSAT Dr Med Vet CLARE R. GREGORY DVM Dipiomate ACVS GERALD V. LING dvm GEORGE H. CARDINET dvm PhD ERNEST L. LEWIS md 《Veterinary surgery : VS》1993,22(4):260-268
Cystourethropexy was performed in 10 bitches with refractory urinary incontinence due to urethral sphincter mechanism incompetence. All animals had an abnormally shaped vesico-urethral junction. The bladder neck was located in the pelvic canal in nine dogs (pelvic bladder). Surgery alone restored urinary continence in two cases and markedly improved incontinence in two cases. Surgery combined with medical therapy (phenylpropanolamine, 1.5 mg/kg orally once or twice a day, using a sustained-action preparation) restored urinary continence in four cases and markedly improved continence in one case. Surgery, with medical therapy, was completely ineffective in one case. No major complications were encountered in any dogs. In four cases, histopathologic evaluation of the dorsal bladder wall and neck revealed the presence of a single, perinuclear, clear vacuole in the cytoplasm of smooth muscle fibers. Electron microscopic examination showed that the vacuoles represented a dilatation of normal membrane organelles. Such abnormalities have the potential to alter the smooth muscle motility. This study indicates that cystourethropexy alone restored urinary continence only temporarily in the majority of the patients. The significance and frequency of the histopathologic findings requires further investigation. 相似文献