蜂胶治疗奶牛慢性化脓性子宫内膜炎

临床上我们试选择蜂胶治疗奶牛慢性化脓性子宫内膜炎,结果较为满意.     

奶牛子宫内膜炎病原菌药敏试验

在奶牛子宫内膜炎病原菌分离试验的基础上,选检出率最高的大肠杆菌、链球菌和葡萄球菌各6株,用10种抗生素进行药敏试验。结果表明,头孢噻肟、丁胺卡那霉素最敏感,其次是利福平和新霉素,其他如庆大霉素、氨苄青霉素、红霉素、强力霉素、土霉素和复合磺胺等6种抗生素均有不同程度的耐药性。     

奶牛子宫内膜炎细菌检验及其药敏试验

子宫内膜炎的病原菌种类较多,国内外学者的报道并不一致,这可能与奶牛的地区气候条件、环境因素、饲养类型及健康水平、选用抗菌药物情况不同而有差异。所以每一地区应该定期调查子宫内细菌的变化,一些抗菌药物通过长时期反复的使用,往往会产生抗药菌株,这种菌株通过感染,致使原来敏感度很高的药物失去治疗作用。本试验主要目的是了解黑龙江省某地区奶牛子宫内膜炎的细菌种类,对常用的抗菌药物的敏感度以求达到比较正确合理使用抗菌药物,提高繁殖存活力,减少浪费,增加奶牛业的经济效益。１　材料和方法１１　待检病料　产犊２周…     

碘伏加抗生素治疗奶牛慢性子宫内膜炎的试验

慢性子宫内膜炎是奶牛的常见多发病,是影响母牛受胎的重要因素。碘伏是一种新型含碘杀菌剂,对组织及粘膜的刺激较轻,不易产生过敏反应。我们应用碘伏加抗生素与常用方法高锰酸钾溶液冲洗后加抗生素,对５６例病牛进行了对比治疗试验,获得满意结果,现报告如下：１材料...     

奶牛子宫内膜炎的治疗

1子宫内膜炎的治疗1.1隐性子宫内膜炎的治疗1.1.1症状母牛发情正常,但配种不易受妊。发情时流出的黏液较正常牛稀薄,粘性弱,发情黏液最多,混浊或含有絮状物。冲洗子宫的回流液经静止后,有蛋白絮状物沉淀。阴道无异常;直肠检查时子     

奶牛子宫内膜炎的治疗体会

奶牛子宫内膜炎是奶牛的一种多发疾病,会导致奶牛长期不孕,严重时会影响养牛业的经济效益。本试验于2009年7月～2010年12月尝试用无抗药物治疗子宫内膜炎,并收集发病奶牛子宫脓性分泌物,分离细菌,进行药敏试验;对患子宫内膜炎的奶牛进行不同药物分组治疗后配种,计算受胎率,比较几种不同分组药物的治疗效果。结果表明,抗生素类药物的治疗效果最好。     

蜂胶治疗奶牛慢性化脓性子宫内膜炎的疗效观察

蜂胶治疗奶牛慢性化脓性子宫内膜炎的疗效观察丁翠华（黑龙江八一农垦大学·密山·１５８３０８）邢茂文，刘加明，马洪图，付贵才（红五月农场，八五五农场，尖山农场）奶牛子官内膜炎是常发病，也是奶牛不孕重要原因之一。目前治疗奶牛子宫内膜炎的方法和药品很多，但是...     

奶牛子宫内膜炎的治疗

奶牛不孕不仅影响奶牛繁殖率和产奶量 ,也直接影响奶牛业发展。奶牛不孕的病因很多 ,其中以子宫内膜炎最为多见。1　子宫内膜炎的病因1 1　难产　奶牛在生产时由于胎儿体形过大或胎位不正而出现难产 ,在助产过程中容易对子宫内膜造成伤害 ,继而产后患子宫内膜炎。1 2　胎衣不下　由于母牛妊娠期运动不足或者羊水过多、胎儿过大 ,也有临床时热应激反应造成胎衣不下。如果剥离时间过晚 (超过 12ｈ)造成胎衣腐败或者进行手术剥离胎衣时动作过大、过猛伤及子宫而引起子宫内膜炎。1 3　助产感染　助产时后躯或助产器械没有充分消毒致使子宫感染引…     

治疗奶牛子宫内膜炎经验介绍

奶牛的子宫膜炎是影响奶牛业发展的一个严重问题,也是当前兽医临床中常见的疾病之一。根据病程的长短,可分为急性和慢性两种。由于子宫分泌物和粘膜受损伤的程度不同,又可分为急性脓性卡他性炎、假膜性炎、坏死性炎、慢性卡他性炎、慢性隐性炎、子宫积水、子宫积脓等多     

奶牛子宫内膜炎致病菌的分离鉴定及耐药性分析

本试验通过对四个大型奶牛场的60头子宫内膜炎患牛进行调查、采样，并用常规的方法对细菌进行分离、培养、鉴定。共分离到细菌59株，其中分离率最高的是埃希氏大肠杆菌14株（23．7％）、葡萄球菌属12株（20.3％）、链球菌属7株（11．8％）（其中溶血性链球菌2株）、棒状杆菌属7株（11．8％）、双球菌5株（8．5%）、肠杆菌属6株（10．16％）、沙门氏菌3株（5．1％）、克雷伯氏杆菌属2株（3．4％），而且分离到了梭菌属3株（严格厌氧菌），药敏试验分析显示，大多数致病菌对喹诺酮类药物、阿莫西林及氨苄青霉素等药物耐药率较高．而对头孢菌素类药物和氨基糖苷类药物耐药率则较低。     

奶牛子宫内膜炎的诊治

子宫内膜炎（puerperal endometritis）为子宫内膜的急性炎症，是奶牛生殖疾病的常见病，发病率高达20％～40％，占不孕症的70％左右。奶牛患子宫内膜炎使受精卵不能着床或胚胎早期死亡，延长了产犊间隔，严重地影响了奶牛的繁殖力和生产性能，降低了奶牛养殖业的经济效益，阻碍了奶牛业的发展。     

奶牛子宫内膜炎防治实用技术

奶牛子宫内膜炎是由致病微生物感染而引起的子宫黏膜炎症,是奶牛繁殖中的一种常见疾病。奶牛患子宫内膜炎时,影响受精和胚胎发育,是导致不孕的主要原因。该病不仅严重影响奶牛的繁育性能和产奶量,还可引发乳房炎等其他疾病,重症者可因丧失经济价值而被淘汰,给奶牛养殖造成严重危害和经济损失。我国成年奶牛子宫内膜炎发病率平均为18％以上,占成年母牛不孕的68％左右。     

非抗生素疗法在防治奶牛子宫内膜炎上的研究概况

奶牛子宫内膜炎是造成奶牛不孕症的主要原因之一,对奶牛业的危害较大。国内外学者对奶牛子宫内膜炎的防治作了大量研究,提出了许多行之有效的治疗方法。目前治疗本病的非抗生素治疗方法包括生物疗法、激素疗法、物理疗法、中草药疗法等。但最有应用前景的是生物疗法和中草药疗法。今后应加强生物疗法和中草药方面的研究,同时应加强中草药制剂的质量控制和安全性评价,以及中草药的作用机理方面的研究。     

Rationale for treatment of endometritis in the dairy cow

Endometritis is an inflammation of the uterine lining that is commonly initiated at parturition. The degree of its effect on fertility varies with the severity of the inflammation, the time required for resolution of endometrial lesions, and the extent of permanent changes that impair endometrial gland functions and/or alter the uterine and/or oviductal environment. The primary nonspecific organisms associated with endometrial pathology are Corynebacterium pyogenes and the gram-negative anaerobes. The majority of postpartum dairy cows have some degree of endometritis but resolve it by 40 to 50 days post partum. Cows with certain periparturient disorders involving the reproductive tract and/or a defective host immune mechanism may acquire persistent infections that impair subsequent fertility. Not all infertile cows or all cows with positive uterine cultures have endometritis. Cows recovering from C. pyogenes endometritis may require 1 month after clearance of the organism for fertility to be restored. These cows, as well as many cows with slightly delayed uterine involution at 30 days post partum, do not benefit from antimicrobial therapy. The effect of endometritis varies between herds. It is associated with prolongation of calving intervals that can vary from less than 2 weeks to 2 months or more. The cost of days open beyond 80 to 110 days post partum is currently estimated to be $2.00 to $2.25 per day. Evaluation of the bovine genital tract is best conducted by a rectal examination combined with a vaginal speculum examination. Cows selected for therapy for endometritis should meet the strict requirements of a grossly enlarged uterus and a severely abnormal uterine discharge. Induction of estrus is the treatment of choice whenever possible. When antimicrobial therapy is indicated, tetracycline is recommended for intrauterine use during the early postpartum period when mixed bacterial populations are present. Commonly used doses are 2 to 3 gm. For systemic signs of illness, systemic administration of penicillin has been recommended. Twice daily doses of 5000 to 10,000 IU of penicillin per kg may be necessary to maintain therapeutic blood concentrations. Systemic administration of an antimicrobial is necessary to achieve therapeutic concentrations in the oviducts, cervix, and vagina. With chronic endometritis due to C. pyogenes, intrauterine administration of 1 to 1.5 X 10(6) IU of procaine penicillin G has been recommended. Multiple daily treatments are desirable. Milk from treated cows should be tested for penicillin before it is added to bulk tank milk. It still is not clear whether antimicrobial therapy is cost effective.(ABSTRACT TRUNCATED AT 400 WORDS)     

产后子宫内膜炎患牛子宫内膜肥大细胞的研究

本研究旨在探讨子宫内膜肥大细胞在牛子宫内膜炎中的作用.选用产后6～10 d健康及患急性化脓性子宫内膜炎的西门塔尔牛各10头,分别为对照组和试验组,通过ELISA法检测子宫内膜中SP、VIP、组胺浓度,透射电镜观察子宫内膜MC颗粒状态及荧先定量PCR法检测组胺受体H1和H2 mRNA表达情况.结果表明,试验组子宫内膜组织申组胺、SP、VIP含量分别为(80.305±4.002)μg/L、(1 258.06±128.88)ng/L、(615.73±70.50)ng/L,而对照组分别为(39.204±4.278)μg/L、(308.12±9.72)ng/L,(1 667.34±153.4)ng/L,试验组与对照组相比差异均极显著(P＜0.01);试验组子宫内膜固有层MC颗粒数量战少、分布和浓度不均、有空泡形成,对照组子宫内膜固有层MC颗粒较多、分布均匀;试验组中组胺受体H1 mRNA水平显著低于正常组(P＜0.05),组胺受体H2mRNA水平高于正常组,且差异板显著(P＜0.01).结果显示子宫内膜炎时,在神经肽和炎症刺激下使子宫内膜固有层MC脱颗粒大量释放组胺,同时子宫内膜组胺受体H1和H2 mRNA表达失衡,使子宫局部淤血和迟缓,导致子宫免疫力下降,利于病原微生物的繁殖,促进子宫内膜炎的发生发展.     

奶牛产后急性子宫内膜炎血液学研究

为了研究奶牛产后急性子宫内膜炎血液学变化并探讨其发病机制,试验对产后6～8 d正常及患急性化脓性子宫内膜炎奶牛对血液象和卵巢激素浓度及血钙、血磷、总蛋白、胡萝卜素、血糖等生化指标的进行了测定.结果表明:试验组与对照组比较,白细胞数量显著增加,血红蛋白含量显著降低,单核细胞数显著增多,分叶核中性粒细胞数显著减少,淋巴细胞数略有增加;孕酮浓度显著升高,而雌二醇浓度较低;血钙含量升高,血清无机磷、血糖和胡萝卜紊水平降低.     

浅谈奶牛子宫内膜炎

随着人们生活水平的不断提高。我国乳业在迅速的发展,奶牛养殖业也在大规模地扩增。奶牛的不孕症是奶牛四大类疾病之一,而子宫内膜炎是奶牛不孕症的主要原因之一。子宫内膜炎是奶牛生产中的常见病,一旦发生,奶牛配种困难或长期不孕,导致养殖效率低,甚至提前淘汰。抓好子宫内膜炎的预防和治疗,对促进奶业增效、奶农增收意义重大。据报道,我国奶牛子宫内膜炎型不孕症占成年母牛不孕症的17％以上。每年美国有12．19％的奶牛患有繁殖疾病。经济损失近2．5亿美元;英国报道的不孕牛中约95％是由于子宫内膜炎引起的。在国内,1984～1988年,中国农业科学院中兽医研究所对10个城市30个奶牛场的10495头适龄母牛的调查表明,产后患子宫内膜炎的有2107头．发病率为20．08％。瞿自明等1983～1985年对北京、上海、南宁、兰州等16个城市41个奶牛场调查了9754头适龄奶牛,有1684头发生子宫内膜炎,约占17．26％,占不孕牛的68．34％。由此可见,奶牛子宫内膜炎对畜牧业所造成的经济损失是相当严重的。     

中草药生物合元制剂对奶牛子宫内膜炎防治试验研究

为解决奶牛子宫内膜炎防治对抗生素及化药的长期依赖,本实验将兽用中草药与益生菌进行功能性技术嫁接,制成中草药生物合元制剂,对奶牛子宫内膜炎进行防治试验研究,结果其临床治愈率为83．33％。与抗生素及化药治疗对照组91．67％治愈率相比虽然存在一定差异,但将药物治疗时间或周期相对延长,其使用效果能满足对奶牛子宫内膜炎的防治需求,可替代或减少抗生素及化药的使用,对当前“无抗奶”的生产具有积极的经济及社会效益。     

多西环素泡腾片治疗子宫内膜炎和胎衣不下临床效果观察

为探讨多西环素泡腾片对子宫内膜炎和胎衣不下治疗作用,对患病奶牛用多西环素泡腾片进行1～3个疗程的治疗,观察临床效果。结果显示,104例为奶牛子宫内膜炎,治疗后有效率98.77%,治愈率93.27%。126例为奶牛胎衣不下,治疗后有效率98.23%,治愈率95.24%。表明多西环素泡腾片对奶牛子宫内膜炎和胎衣不下有较好的治疗效果。     

Preliminary results of treatment and endocrinology of chronic endometritis in the dairy cow

Cows with chronic endometritis were treated by using uterine irrigation, prostaglandin or oestradiol benzoate. An attempt was made to relate the success of treatment to the nature of the discharge. No statistically significant differences were demonstrated between the different treatments, nor did the severity of the disease as judged by the amount of pus in the discharge affect the success of treatment. Progesterone and in some cases a metabolite of prostaglandin were measured in a milk sample taken at the time of treatment. Increased prostaglandin concentrations were found in 69 of 71 samples examined but they were not correlated with the progesterone concentrations. These measurements from cases of endometritis were higher than those from normal cows in the immediate post partum period and during established oestrous cycles. Treatment with prostaglandin when the concentration of progesterone was high was not more effective than when progesterone concentrations were low. Treatment had less influence on the subsequent fertility of the cow than other factors investigated; in particular, the sooner after calving the cow was treated the greater was the chance of success. This was thought to be due, at least in part, to the high rate of spontaneous recovery. Before treatment can be evaluated effectively a method must be found to identify persistent cases.