Estimation of additive and non-additive genetic parameters for reproduction, growth and survival traits in crosses between the Moroccan D'man and Timahdite sheep breeds

Genetic breed differences, heterosis, recombination loss, and heritability for reproduction traits, lamb survival and growth traits to 90 days of age were estimated from crossing D'man and Timahdite Moroccan breeds. The crossbreeding parameters were fitted as covariates in the model of analysis. The REML method was used to estimate (co)variance components using an animal model. The first estimation of crossbreeding effects for Timahdite and D'man breeds shows that breed differences in litter traits are mainly of maternal genetic origin: +1.04 lambs, +1.88 kg, +0.60 lambs, and +2.23 kg in favour of D'man breed for litter size at lambing, litter weight at lambing, litter size at weaning, and litter weight at 90 days, respectively. The breed differences in lamb growth and survival are also of maternal genetic origin for the majority of traits studied, but in favour of the Timahdite breed: +3.48 kg, +45 g day⁻¹ and +0.19 lambs for weight at 90 days, for average daily gain between 30 and 90 days of age, and for lamb survival to 90 days, respectively. The D'man direct genetic effect was low and negative for survival and birth weight of lambs during the first month of life. All traits studied showed positive heterosis effects. Recombination loss effects were not significant. Therefore, crossbreeding of Timahdite with D'man breeds of sheep can result in an improved efficiency of production of saleable lambs. Heritability estimates were medium for litter size but low for the other reproduction traits. Direct heritabilities were low for body weights and lamb survival at 90 days and the corresponding maternal heritabilities showed, however, low to moderate estimates. For litter traits, the estimates of genetic and phenotypic correlations were positive and particularly high for genetic correlations.     

Phenotypic and genetic parameter estimates for reproductive traits in Zandi sheep

This study reports on the phenotypic and genetic (co)variance components for reproductive traits in Zandi sheep, using between 1,859 and 2,588 records obtained from 577 ewes. The data were collected from the Khojir Breeding Station of Zandi sheep in Tehran, Iran from 1994 to 2008. The basic traits were litter size at birth (LSB), litter size at weaning (LSW), litter mean weight per lamb born (LMWLB), and litter mean weight per lamb weaned (LMWLW), and the composite traits were total litter weight at birth (TLWB) and total litter weight at weaning (TLWW). Genetic analyses were carried out using the restricted maximum likelihood method that was explored by fitting the additive direct genetic effects and permanent environmental effects of the ewes as random effects and the ewe age at lambing and lambing year as fixed effects for all of the investigated traits. Akaike’s information criterion was used to choose the most appropriate model. LSB, LSW, LMWLB, LMWLW, TLWB, and TLWW direct heritability estimates were 0.07, 0.05, 0.12, 0.10, 0.08, and 0.14, respectively. The estimated fractions of variance due to the permanent environmental effects of the ewe ranged from 0.03 for LMWLB to 0.08 for LMWLW and TLWW. Corresponding repeatability estimates ranged from 0.10 for LSW to 0.22 for TLWW. Direct genetic correlations varied from ?0.61 for LSB–LMWLB to 0.88 for LSB–LSW and LSB–TLWB. Results indicate that genetic change depends not only on the heritability of traits, but also on the observed phenotypic variation; therefore, improvement of non-genetic factors should be included in the breeding programs.     

Genetic selection for increased mean and reduced variance of twinning rate in Belclare ewes

It is sometimes possible to breed for more uniform individuals by selecting animals with a greater tendency to be less variable, that is, those with a smaller environmental variance. This approach has been applied to reproduction traits in various animal species. We have evaluated fecundity in the Irish Belclare sheep breed by analyses of flocks with differing average litter size (number of lambs per ewe per year, NLB) and have estimated the genetic variance in environmental variance of lambing traits using double hierarchical generalized linear models (DHGLM). The data set comprised of 9470 litter size records from 4407 ewes collected in 56 flocks. The percentage of pedigreed lambing ewes with singles, twins and triplets was 30, 54 and 14%, respectively, in 2013 and has been relatively constant for the last 15 years. The variance of NLB increases with the mean in this data; the correlation of mean and standard deviation across sires is 0.50. The breeding goal is to increase the mean NLB without unduly increasing the incidence of triplets and higher litter sizes. The heritability estimates for lambing traits were NLB, 0.09; triplet occurrence (TRI) 0.07; and twin occurrence (TWN), 0.02. The highest and lowest twinning flocks differed by 23% (75% versus 52%) in the proportion of ewes lambing twins. Fitting bivariate sire models to NLB and the residual from the NLB model using a double hierarchical generalized linear model (DHGLM) model found a strong genetic correlation (0.88 ± 0.07) between the sire effect for the magnitude of the residual (V_E) and sire effects for NLB, confirming the general observation that increased average litter size is associated with increased variability in litter size. We propose a threshold model that may help breeders with low litter size increase the percentage of twin bearers without unduly increasing the percentage of ewes bearing triplets in Belclare sheep.     

Genetic parameters for ewe productivity traits in the Columbia, Suffolk and Targhee breeds

Estimates of repeatability and heritability were obtained for the following productivity traits of ewes: litter weight at birth (LWB) and weaning (LWW), litter size at birth (LSB), litter size alive at birth (NBA), litter size at weaning (LSW), neonatal survival rate (SRB) and preweaning survival rate (SRW). Phenotypic and genetic correlations were estimated for litter traits. The data set contained 6,394 ewe breeding records from three state stations over 10 yr on 1,731 ewes that were the progeny of 488 sires among three breeds (Columbia, Suffolk and Targhee). Pooled intra-station estimates of repeatability ranged from .11 to .22 for LWB and LWW among the three breeds. For litter size at birth, number born alive and litter size at weaning these estimates varied from .09 to .17 and for the survival traits (SRB and SRW) the variation was from .11 to .20. Intra-station estimates of heritability for the three breeds varied from .12 to .28 for LWB and LWW, and for LSB, NBA and LSW estimates varied from .05 to .35. Heritability estimates for survival traits (SRB and SRW) were low, ranging from .00 to .14. Phenotypic correlations among LWB, LWW, NBA and LSW ranged from .35 to .92 among the breed-station subclasses, with higher correlations occurring where a part-whole relationship existed. The study suggests that selection of ewes with high litter size at birth or at weaning and(or) litter weight at birth or at weaning will genetically improve total litter weight at weaning per ewe lambing.     

Analysis of litter size and days to lambing in the Ripollesa ewe. II. Estimation of variance components and response to phenotypic selection on litter size

A performance data set from 376 Ripollesa purebred ewes of the experimental flock of the Universitat Autònoma of Barcelona was analyzed using a bivariate Bayesian threshold-linear model. The data set contained 1,598 litter size records and 1,699 days-to-lambing records. The model included the additive genetic effect of each animal and 3 nongenetic sources of variation: ewe age, year of lambing, and the permanent environmental effect characterized by the ewe. The flock was phenotypically selected for litter size since 1986, and replacement ewes and rams were selected from the progeny of the more prolific ewes, which had at least 3 deliveries recorded. The phenotypic trend for litter size was positive, whereas days to lambing followed an unclear pattern. Both traits had low heritabilities; 0.13 for litter size and 0.11 for days to lambing. Response to selection was evaluated through (a) the average breeding value of the ewe lambs chosen annually, and (b) the average breeding value of the overall flock. The first measurement suggested a positive trend for litter size, although it showed important oscillations. On the other hand, the average breeding value for the overall flock showed a stable positive tendency after yr 4 of selection, with estimates clearly different from zero after yr 11 of selection. A significant increase in the incidence of multiple births was observed, with a mode of approximately 10%. The correlated response in days to lambing did not show a significant trend. The effect of year of lambing also positively influenced both litter size and days to lambing, although important oscillations were observed between years. Results indicated that litter size in sheep can be effectively improved through phenotypic selection, even in small flocks; moreover, days to lambing could also be genetically improved, given the estimate obtained for its heritability.     

Evaluation of melatonin receptor 1a as a candidate gene influencing reproduction in an autumn-lambing sheep flock

The effect of the melatonin receptor 1a (MTNR1A) gene on fertility and litter size in autumn lambing was studied with 373 ewes from a population of sheep selected for 10 yr for fertility in May and June matings. Animals were from a composite line of 50% Dorset, 25% Rambouillet, and 25% Finnsheep. Two restriction fragment length polymorphisms were present in the population, with allelic frequencies of 0.42 and 0.58 for an MnII polymorphism (alleles M and m, respectively) and of 0.34 and 0.66 for an RsaI polymorphism (alleles R and r, respectively). Genotypic frequencies for the polymorphisms were not independent, suggesting an association between them in foundation animals. Effects of MTNR1A genotype on fertility and litter size were evaluated using mixed linear model or REML procedures, but were not significant for matings involving ewes of all ages. However, in adult ewes (3 yr old and older), fertility of ewes of genotype mm was 10.0 (mixed model; P < 0.09) to 11.2% (REML; P = 0.03) less than that of other ewes. Genotypic effects associated with MTNR1A in adult ewes accounted for 23.8% of the estimated total additive genetic variance in fertility. Litter size was not significantly associated with MTNR1A genotype; adult ewes of genotype mm had approximately 0.11 fewer lambs per ewe lambing than ewes of other genotypes. Fertility in autumn lambing is lowly heritable, expressed only in females, and manifested relatively late in life and only in some management systems. Access to genetic markers would thus be advantageous in selection programs.     

Reproductive performance and genetic parameters in first cross ewes from different maternal genotypes

The reproduction of 2,846 crossbreed ewes with 7,899 records is reported. The ewes were progeny of mainly Merino dams and 91 sires from several maternal sire breeds including Border Leicester, East Friesian, Finnsheep, Coopworth, Corriedale, Booroola Leicester, and several others. There were 3 cohorts of ewes at each of 3 sites that were bred naturally to meat-type rams for each of 3 yr to evaluate reproduction and lamb production. At 2 sites, the ewes were mated in the autumn, first at 7 mo of age, and at 2 sites the ewes were mated in the spring, first at 14 or 17 mo of age. The cohorts of ewes and sites were genetically linked by 3 common sires. Mixed linear models were used to analyze ultrasound scanned pregnancy rate, fetal number, fertility (ewes lambing), litter size, lamb survival, number of lambs born (NLBj), number of lambs weaned (NLWj), and total weight of lamb weaned (TWWj) per ewe bred. Fixed effects included sire breed (1 to 10), environment (1 to 4, site and season of breeding: autumn, spring), breeding (1 to 3), cohort (1 to 3), and their interactions. The REML procedures were used to estimate (co)variance components. Ewe sire breed effects were significant (P < 0.01) for all the reproductive traits and breed means ranged from 0.75 to 0.96 for fertility, 1.22 to 2.08 for litter size, 0.70 to 0.90 for lamb survival, 0.99 to 1.66 for NLBj, 0.87 to 1.26 for NLWj, and 22.9 to 33.8 kg for TWWj, with the ranking of sire breeds varying for different traits. For all traits except lamb survival, the contrast between breeding 1 vs. 2 and 3 was considerably greater than the contrast between breeding 2 vs. 3, with significant environment x breeding interactions (P < 0.01). Estimates of heritability for the components of reproduction ranged from 0.03 +/- 0.02 for lamb survival to 0.19 +/- 0.05 for litter size, and those for the composite traits were 0.17 +/- 0.04 for NLBj, 0.13 +/- 0.04 for NLWj, and 0.17 +/- 0.04 for TWWj, with repeatability ranging from 0.10 to 0.19. Genetic and phenotypic correlations among the traits are reported. The significant variation among sire breeds of the crossbred ewes can be used to improve reproduction, although there was a change in the rank of the breeds for the various traits. There was considerable overlap between the breeds, and additional improvement could be achieved by exploiting the genetic variation between sires within breeds for all the ewe reproductive traits.     

Lambing date and lamb production of spring-mated Rambouillet, Dorset and Finnsheep ewes and their F1 crosses

The reproductive performance of 255 Rambouillet (R), Dorset (D), Finnsheep (F) and F1 ewes born in 1978-1979 (group I) and 1979-1980 (group II) and managed in a semiconfinement fall/winter lambing system was evaluated through 4 yr of age of all ewes and through 5 yr for a portion of group I ewes. Ewes were with rams from approximately May 1 to late September each year, with a 2-wk break late in July/early August. Traits considered were fertility (ewes lambed/ewes exposed), lambing date, litter size, lamb survivial and 70-d lamb weights. Breeds and crossbred groups differed significantly in lambing date, with DR crossbred ewes earliest and F ewes latest. Repeatabilities for groups I and II were .31 and .22, .24 and .24 and .11 and .07 for lambing date, fertility and litter size, respectively. There was no significant heterosis in lambing date, although DR ewes in both groups I and II were superior to (D + R)/2, by about 1 wk on average. There was significant positive heterosis for fertility and traits of which fertility is a component in FR ewes in group I, but none in group II. The FD ewes showed negative heterosis for litter size, -.23 (P less than .05) for group I and -.09 for group II. The results indicate: F and FD ewes are not well adapted to the Mediterranean climate where this experiment was conducted; there is little, if any, useful heterosis in crosses among these three breeds for lambing date or other reproduction traits and RD and R ewes are most suitable of the groups tested, while late onset of the breeding season limits the usefulness of even 50% Finnsheep ewes for an autumn lambing system in this environment.     

Genetic analysis of litter size in Targhee, Suffolk, and Polypay sheep

Data on litter size, weaning weights at 60, 90, and 120 d, postweaning gains from weaning to 120 or 365 d of age, fleece weight, and fiber diameter from Targhee, Suffolk, and Polypay flocks participating in the U.S. National Sheep Improvement Program were used to estimate genetic parameters for litter size and genetic relationships between early-life traits and future litter size. Records on 7,591 lambings by 3,131 Targhee ewes, 10,295 lambings by 5,038 Suffolk ewes, and 6,061 lambings by 2,709 Polypay ewes were used. Heritability estimates for litter size ranged from .09 to .11 across breeds; repeatability ranged from .09 to .13. Additive genetic effects on litter size were generally positively, and occasionally significantly, correlated with animal additive genetic effects on weaning weights and postweaning gains. Genetic correlations (r(a)) ranged from .08 to .48 in Targhee and from .17 to .43 in Suffolk but were close to 0 in Polypay (-.14 to .09). Additive maternal effects on weaning weight were positively associated with litter size in Suffolk and Polypay; this correlation was negative (-.23 to -.35), but not significant, in Targhee. Fleece weight was not strongly associated with litter size; (r(a) = -.09 to .21). However, fiber diameter had a significant undesirable correlation with litter size (.30) in Targhee. Estimates of phenotypic correlations of litter size with early-life traits were uniformly small (-.02 to .08). Thus, although occasional genetic antagonisms between litter size and early-life traits were observed in these data, none appeared large enough to prevent simultaneous genetic improvement in both traits.     

Lamb production and its components in pure breeds and composite lines. I. Seasonal and other environmental effects

Season of lambing and other environmental effects on ewe performance were analyzed for purebred Finnsheep (F), Rambouillet (R), Dorset (D), Targhee (T) and Suffolk (S) and the generations of crosses in development of two maternal composite lines (1/2F1/4R1/4D) and (1/2F1/4T1/4S) in accelerated (January, May and September) or annual April lambing. The data involved 10,959 ewe breeding season records for 4,219 ewes of 412 sire families over 4 yr. Various measures of ewe productivity and its components (fertility, litter size, neonatal and preweaning survival and weaning weight) were analyzed. Fertility was higher for annual April than for accelerated May or January lambing and was sharply lower for September lambing. Fertility of F and F-cross ewes was significantly higher for May and lower for January lambings relative to R and D ewes. Litter size also was higher in annual April (1.9) than in January (1.8) or May (1.7) and September (1.4). Neonatal and preweaning survival was higher in September when litter size was smaller. Mean weaning weights were depressed in the larger April and May litters. Thus, weight of lambs weaned/ewe exposed was higher for annual April than for May and January lambing and was very low for September lambing. Hormone treatment of ewes for September lambing increased fertility from 16 to 44% and litter size from 1.6 to 1.8. Short lambing interval (8 mo vs 12+ mo) reduced mean ewe fertility by five percentage points, and most for the January lambing of Finnsheep ewes.     

Genetic variation in litter size and kit survival of mink (Neovison vison)

The aims of this study are to estimate variance components of litter size and kit survival rate and estimate genetic correlations of litter size and kit survival rate with dam's juvenile body weight and pregnancy length. Variance components for litter size and kit survival were analysed using an AI-REML approach, based on data from 1940 litters of the black colour type mink from 1996 to 2001. The models included (i) additive genetic effect of dam; (ii) dam and sire genetic effects; (iii) additive genetic effect of dam in relation to litter size and dam and sire genetic effects in relation to survival rate; (iv) additive genetic effect of dam to estimate the correlations of litter size or kit survival with dam juvenile body weight and pregnancy length on yearling dams (1357 litters). The dam heritabilities were of litter size (0.02-0.08) and survival rate (0.05-0.10). The permanent effects of dam were important for litter size (0.15-0.19) but not for survival rate. A positive dam genetic correlation between litter size and survival rate was found at 1 week postpartum (0.42), and a positive sire genetic correlation between number of weaned kits and survival rate at the age of 6 month (0.72). Litter size and survival rate were genetically antagonistically related to dam's juvenile body weight (-0.34 to -0.53). These results indicate the following: (i) it is possible to improve litter size and kit survival by selection, (ii) effective improvement of kit survival rate in the suckling period requires selection for maternal effect on kit survival and kit's own capacity to survive and later in the growth period for kit's own ability to survive and (iii) antagonistic genetic correlation of dam juvenile body weight with litter size and survival rate should be taken into consideration in mink breeding programs.     

Comparison of performance of F1 Romanov crossbred ewes with wool and hair breeds during spring lambing under intensive and extensive production systems

The objective was to evaluate wool (Dorset and Rambouillet) and hair (Dorper, Katahdin, and White Dorper) breeds for their ability to complement Romanov germplasm in two distinct production systems by estimating direct sire and grandsire effects on lamb growth, survival, and ewe productivity traits. Rams of the five breeds (n = 75) were mated to Romanov ewes (n = 459) over a 3-yr period to produce five types of crossbred lambs (n = 2,739). Sire breed (P > 0.06) did not impact body weight or survival traits of the first-generation crossbred (F1) lambs. The productivity of retained crossbred ewes (n = 830) mated to Suffolk and Texel terminal sires was evaluated at 1, 2, and 3 yr of age in each production system. In the intensive production system, labor and harvested feed were provided for sheep that lambed in March in barns, and ewes were limited to rearing two lambs with additional lambs reared artificially. Ewes in the extensive production system lambed in May on pasture and were responsible for rearing all lambs born with no labor or supplemental feed provided before weaning. A total of 1,962 litters and 4,171 lambs from 2,229 exposures to two terminal sire breeds (Suffolk and Texel) were produced in the experiment. Crossbred ewes in the intensive production system were mated in October, resulting in larger litter sizes than crossbred ewes mated in December for the extensive production system. However, single- and twin-born lamb mortality was similar between the two systems that differed greatly in labor, feed, and facilities. Lambs produced in the intensive system received concentrate feed from an early age and were heavier at 24 wk of age than lambs produced in the extensive system. These outcomes resulted in greater 24-wk litter weight in the intensive than in the extensive system (P < 0.0001). Unexpectedly, the relative performance of crossbred types did not differ importantly between production systems. White Dorper × Romanov crossbred ewes had numerical advantages in productivity in each system; however, differences between ewe types were not significant. In the extensive system, without labor and shelter at lambing or supplemental feed until weaning, 3-yr-old crossbred ewes of all types averaged 1.78 lambs marketed per ewe lambing, and 40% of the ewes that gave birth to triplets weaned their entire litters. These results document that prolific sheep and extensive systems can be successfully combined if appropriate crossbred types are used.     

Usefulness of subjective ovine milk scores: II. Genetic parameter estimates

Genetic parameters for a subjective milk score given to ewes within 24 h of parturition were estimated to determine the usefulness of milk score as a selection trait to improve milk production, which influences total litter weight weaned. Heritability of milk score and the genetic correlation of milk score with litter weight weaned were estimated by REML separately for four sheep breeds, Rambouillet (n = 1,731), Targhee (n = 1,638), Columbia (n = 1,731), and Polypay (n = 1,129). Litter weight weaned was the total weight of lambs weaned at approximately 120 d of age under a western range production system. Observed heritability estimates for milk score at first parity were moderate and similar among breeds, ranging from 0.18 to 0.32. Heritability estimates adjusted for a binomial distribution of milk scores at first parity were high (Columbia, 0.43; Polypay, 0.35; Rambouillet, 0.50; Targhee, 0.84). Estimates of observed heritability for second-parity milk score were moderate to high, ranging from 0.23 to 0.46. Milk score at first or second parity was genetically correlated with milk score records at maturity (third parity and greater), with estimates ranging from 0.69 to 1.00. Milk score and litter weight weaned were genetically correlated at first or second parity in Rambouillet (r(g) = 1.00) and Targhee breeds (r(g) = 1.00 and 0.61, respectively), but not in the Columbia and Polypay breeds. Estimates of heritability for lifetime records for milk score ranged from 0.16 to 0.26 across breeds. Estimates of genetic correlations of annual lifetime milk score records with litter weight weaned were high (Columbia, 1.00; Polypay, 0.81; Rambouillet, 1.00; and Targhee, 0.77). Repeatability estimates for milk score were similar across breeds, 0.23 for Columbia, Rambouillet, and Targhee ewes and 0.28 for Polypay ewes. Milk score measured at first or second parity may be a good predictor of future potential milking ability. Further, milk score can be used as a selection trait to improve maternal ability for increasing litter weight weaned. The need for increasing ewe milking performance and lamb growth rate at first parity in commercial range sheep production systems may be addressed by selection for milk score at first parity.     

Usefulness of subjective ovine milk scores: I. Associations with range ewe characteristics and lamb production

Range ewes are commonly evaluated for milking ability by producers to determine the ewe's ability to rear lamb(s). The U.S. Sheep Experiment Station has subjectively scored (low, average, high) a ewe's milking ability within 24 h of lambing for many years. The relationship of subjective milk scores with lamb production was investigated using lambing records of Columbia (n = 1,731), Polypay (n = 1,129), Rambouillet (n = 1,704), and Targhee (n = 1,638) ewes. The incidence of high milk scores increased from less than 10% at first parity to 29 to 40% at second and greater parities. At maturity, Columbia ewes (38%) had the highest percentage of high milk scores. A positive association existed between ewe BW and her milk score at third and later parities. Ewes with high milk scores gave birth to heavier lambs (P < 0.05), whereas ewes with low milk scores were associated with lighter (P < 0.05) lambs at birth. Ewes with low milk scores weaned less (P < 0.05) total weight than ewes with better milk scores across all age groups for all breeds. Lighter weaned litter weights from ewes with low milk scores were linked to lighter birth weights and fewer weaned lambs. Differences for litter weight weaned between ewes with average and high milk scores were generally observed at 2 and 3 yr of age, when litter weights were heavier among ewes with high milk scores (P < 0.05) for all breeds. Between the ages of 1 and 3 yr, Columbia, Polypay, Rambouillet, and Targhee ewes with an average milk score weaned heavier (P < 0.05) litters (average differences of 10, 9, 13, and 12%, respectively) than ewes with low milk scores. For all breeds at all ages, individual lamb weaning weights were heavier (P < 0.05) when they were reared by ewes with high milk scores compared to lambs reared by ewes with low milk scores. Results suggest that milk score is an economically important trait in these four breeds and should be considered in management and breeding objectives; at a minimum, the incidence of low milk scores should be kept as small as possible.     

Straightbred comparison of a composite population and the Suffolk breed for performance traits of sheep

A terminal sire Composite population was formed by mating Columbia rams to Hampshire-Suffolk crossbred ewes. Subsequent generations were produced by inter se mating. The objective was to compare Composite sheep to purebred Suffolks for numerous performance traits. Young ewes lambing at 1 yr of age were evaluated separately from mature ewes (2, 3, 4, and 5 yr old) of each population. Composite and Suffolk populations did not differ significantly in components of litter weaning weight per young ewe joined. Mature Composite ewes produced more wool than Suffolk ewes. Fertility of mature ewes did not differ significantly between populations. The greater prolificacy (P less than .01) of mature Suffolk ewes was offset by a lower survival to weaning (P less than .01), particularly for twin-born lambs. Consequently, mature Composite and Suffolk ewes did not differ for number weaned and litter weaning weight per ewe joined. The average birth weight of lambs born to young and mature Composite ewes was greater (P less than .02) than the average birth weight of Suffolk lambs. The average weaning weight of lambs born to young Composite ewes was greater (P less than .05) than that of lambs born to young Suffolk ewes. Breed differences were not detected for preweaning daily gains, weaning weights, and postweaning daily gains of ewe lambs born to mature ewes. Likewise, weights of ewes at 125 d of age and weights of mature ewes at breeding did not differ significantly between breeds.(ABSTRACT TRUNCATED AT 250 WORDS)     

Inheritance of active and acquired immunity traits in sheep

Six hundred sixteen ewes of six strains were inoculated twice with ovalbumin in Freunds' incomplete adjuvant. To quantify the humoral immune response to the foreign antigen, blood samples were collected from all ewes 1 wk post-second injection. Blood samples were also collected between 4 and 40 h of age from their 709 lambs, to examine genetic differences in ability of lambs to acquire maternal anti-ovalbumin antibodies. Titers of anti-ovalbumin antibodies were determined using kinetic enzyme-linked immunosorbent assay (ELISA) techniques. Strain did not affect ewe immune response, but sire within strain was highly significant. In pregnant ewes, anti-ovalbumin antibody titers in 12- and 30-mo-old ewes were higher than those in 21-mo-old ewes. Number of lambs in utero did not significantly affect ewe immune response. Heritabilities of anti-ovalbumin titer from a paternal half-sib analysis were .27 +/- .17 for all ewes and .57 +/- .25 for only the pregnant ewes. The effect of strain of lamb on lamb anti-ovalbumin titer approached significance, and sire within strain was highly significant. Lamb anti-ovalbumin antibody concentration increased as time from birth to blood sampling increased to 18 h but declined thereafter. The size of the litter in which a lamb was born had a highly significant effect on the lamb's acquired immunity, with titer decreasing as litter size increased. The heritability estimate for lamb anti-ovalbumin antibody concentration from a paternal half-sib analysis was .38 +/- .11; it was .28 +/- .15 from the sire variance component of a full-sib analysis. When lamb titer was considered a maternal trait (lambs nested within their maternal grandsires within strains), the maternal grandsire variance component was negative. The average anti-ovalbumin antibody concentration of lambs that died between blood sample collection and 120 d of age was less than the average antibody concentration of lambs that survived (P less than .01).     

Evaluation of Columbia, USMARC-Composite, Suffolk, and Texel rams as terminal sires in an extensive rangeland production system: I. Ewe productivity and crossbred lamb survival and preweaning growth

A 3-yr study was conducted to comprehensively evaluate columbia, suffolk, usmarc-composite (composite), and texel breeds as terminal sires in an extensive rangeland production system. The objective was to estimate breed-of-ram effects on ewe fertility, prolificacy, and dystocia, and sire breed effects on lamb survival and growth until weaning at approximately 132 d of age. Data were from 22 columbia, 22 composite, 21 suffolk, and 17 texel rams with 957 exposures to 574 adult rambouillet ewes (3- to 7-yr-old at lambing), 908 lambings, and 1,834 lambs. Ram breed did not affect ewe fertility (mean = 94.9%; p = 0.73), total number born per ewe lambing (mean = 2.02 lambs; p = 0.20), number born alive per ewe lambing (mean = 1.90 lambs; p = 0.24), or number weaned per ewe lambing (mean = 1.45 lambs, p = 0.94). Dystocia rates were different (p = 0.01) for ewes mated to columbia (12.2%), composite (13.5%), suffolk (25.7%), and texel rams (31.9%) during 1 yr of the study, but differences among ram breeds were not repeatable (p ≥ 0.38) during the other 2 yr. Suffolk-sired lambs were heavier (p ≥ 0.02) at birth (5.5 kg) and weaning (40.3 kg) than lambs sired by the other breeds, which did not differ (p ≥ 0.34) for birth weight (mean = 5.3 kg). Texel-sired lambs (37.4 kg) were lighter (p ≥ 0.02) at weaning than columbia- (38.8 kg) and composite-sired (38.4 kg) lambs, which did not differ (p = 0.40) for weaning weight. Sire breed effect approached significance (p = 0.06) for lamb survival to weaning; estimated survival probabilities were 0.87 (columbia), 0.89 (composite), 0.93 (suffolk), and 0.86 (texel) for lambs reared by their birth dam. Interaction between sire breeds and birth weight affected (p < 0.001) lamb survival and revealed that lightweight columbia- and suffolk-sired lambs had a greater risk of death than lightweight lambs sired by composite and texel rams, but risk of death did not increase substantially for heavyweight lambs from any of the breeds. When mated to adult rambouillet ewes in an extensive rangeland production system, the use of suffolk rams is warranted to improve preweaning growth of market lambs and is not predicted to affect ewe fertility, ewe prolificacy, dystocia, or lamb survival compared with the other sire breeds we tested.     

Effects of alternative lamb production systems, maternal line, and culling strategy on flock age structure.

The 5-yr attrition of 1/4 (n = 411) or 1/2 (n = 403) Finnsheep (Finn) ewes exposed to terminal sire breeds in either an accelerated or semi-intensive annual lambing system was recorded to test the effects of system and percentage Finn on flock age structure at equilibrium. Ewes were culled for discernible ailments and failure to lamb after two consecutive non-spring exposures in yr 3, 4, or 5 only. Additionally, four progressively more intensive culling strategies for nonconception were practiced in retrospect. Flock productivity (kilograms of lamb weaned per ewe maintained per year) at age structure equilibrium was estimated for all culling strategies. The majority of all systems (cull strategy x lambing system x percentage Finn combination) were composed of ewes less than or equal to 3 yr old. Replacement requirements ranged from 24 to 38% in the accelerated system and 22 to 26% in the annual system. Quarter-Finns yielded greater replacement needs and shorter productive lives in accelerated lambing but fewer replacement requirements and longer productive lives than 1/2 Finns in annual lambing. Replacement requirements greatly increased with culling intensity in accelerated lambing (up to 54% above original levels) but only slightly in annual lambing (up to 8% above original levels). Mean (reproductive) lifetime estimated from fitted Weibull survival curves ranged from 3.1 to 5.1 yr in accelerated lambing and 4.5 to 5.4 yr in annual lambing. Increased culling for non-lambing decreased productivity at flock age structure equilibrium in accelerated lambing but did not change productivity in annual lambing. Repeatability of ewe effects on conception was generally low. Overall, system, percentage Finn, and culling strategy interact to influence system productivity through flock age structure. Intensive culling for non-lambing and replacement with ewe lambs of equal genetic merit should not be practiced in accelerated lambing systems.     

Estimation of genetic parameters for reproductive traits in shall sheep

The objective of this study was to estimate genetic parameters for reproductive traits in Shall sheep. Data included 1,316 records on reproductive performances of 395 Shall ewes from 41 sires and 136 dams which were collected from 2001 to 2007 in Shall breeding station in Qazvin province at the Northwest of Iran. Studied traits were litter size at birth (LSB), litter size at weaning (LSW), litter mean weight per lamb born (LMWLB), litter mean weight per lamb weaned (LMWLW), total litter weight at birth (TLWB), and total litter weight at weaning (TLWW). Test of significance to include fixed effects in the statistical model was performed using the general linear model procedure of SAS. The effects of lambing year and ewe age at lambing were significant (P?<?0.05). Genetic parameters were estimated using restricted maximum likelihood procedure, under repeatability animal models. Direct heritability estimates were 0.02, 0.01, 0.47, 0.40, 0.15, and 0.03 for LSB, LSW, LMWLB, LMWLW, TLWB, and TLWW, respectively, and corresponding repeatabilities were 0.02, 0.01, 0.73, 0.41, 0.27, and 0.03. Genetic correlation estimates between traits ranged from ?0.99 for LSW–LMWLW to 0.99 for LSB–TLWB, LSW–TLWB, and LSW–TLWW. Phenotypic correlations ranged from ?0.71 for LSB–LMWLW to 0.98 for LSB–TLWW and environmental correlations ranged from ?0.89 for LSB–LMWLW to 0.99 for LSB–TLWW. Results showed that the highest heritability estimates were for LMWLB and LMWLW suggesting that direct selection based on these traits could be effective. Also, strong positive genetic correlations of LMWLB and LMWLW with other traits may improve meat production efficiency in Shall sheep.     

Genetic Aspects of Reproduction in Sheep

Maintenance of high levels of realized fertility (defined as the percentage of ewes that lamb) and appropriate levels of fecundity are critical for efficient sheep production. The optimal level of fecundity in most situations is well below the maximum attainable level and can be targeted by combining selection among and within breeds with use of an expanding array of single-gene mutations affecting ovulation rate and litter size. The heritability of litter size is approximately 0.10, allowing changes of up to 2%/year from simple mass selection. Mutations in several genes associated with the transforming growth factor β superfamily ( BMPRIB , GDF9 and sex-linked BMP15 ) can increase ovulation rates by 0.7–1.5 ova in heterozygous ewes. However, ewes that are homozygous for BMP15 or GDF9 mutations are sterile, so use of these mutations requires carefully structured breeding programmes. Improvements in fertility may be critical for autumn lambing or programmes that aspire to lamb throughout the year. Selection to improve fertility in spring matings has been successful; selected adult ewes have lambing rates of 80–85% in October and early November. The selected ewes have a dramatically reduced seasonal anestrus, and many ewes continue to cycle during spring and summer. Major genes affecting seasonal breeding have not been identified in sheep. Polymorphisms in the melatonin receptor 1a gene appear to be associated with seasonal breeding in some, but not all breeds. However, functional genomic studies of genes associated with circadian and circannual rhythms have potential to reveal additional candidate genes involved in seasonal breeding.