Preliminary antinociceptive, antioxidant and cytotoxic activities of Leucas aspera root

The ethanolic extract of Leucas aspera root was subjected to acetic acid induced writhing inhibition, 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging assay and brine shrimp lethality bioassay for screening of antinociceptive, antioxidant and cytotoxic activity, respectively. The extract produced significant writhing inhibition in acetic acid induced writhing in mice at the doses of 250 and 500 mg/kg. The extract showed a significant free radical scavenging activity with an IC(50) of 8 microg/ml. The extract showed significant lethality to brine shrimp with an LC(50) value.     

Antimicrobial activity of flowers from Anthemis cotula

The flavonoid containing total extract of Anthemis cotula flowers, tested at the concentration of 200 μg/ml, showed interesting antimicrobial activity against both Gram-negative and Gram-positive microorganisms.     

Antimicrobial activity of Centaurea diffusa

The methanol soluble fraction of the aqueous extract obtained from the dry heads of Centaurea diffusa demonstrated antimicrobial activity in twelve evaluated microorganisms.     

Antimicrobial activity of Gymnema sylvestre leaf extract

The ethanolic extract of Gymnema sylvestre leaves demonstrated antimicrobial activity against Bacillus pumilis, B. subtilis, Pseudomonas aeruginosa and Staphylococcus aureus and inactivity against Proteus vulgaris and Escherichia coli.     

Antimicrobial activity of Securinega leucopyrus

Extracts of the leaves of Securinega leucopyrus exhibited a broad spectrum of antimicrobial activity.     

Antimicrobial activity of crude methanolic extract of Satureja khuzistanica

The methanolic extract of the aerial parts of Satureja khuzistanica was investigated for its antimicrobial activity. The maximum antibacterial and antifungal activities were observed against Staphylococcus aureus and Candida albicans.     

Antimicrobial activity and cytotoxicity of Trapa bispinosa

The extracts of Trapa bispinosa showed interesting antimicrobial activity against Gram-positive and Gram-negative test organisms and significant cytotoxic activity.     

Antimicrobial activity of some medicinal plants from India

The results of a preliminary antimicrobial screening of the methanol extracts of Zingiber officinale, Asteracantha longifolia, Citrus acida, Salacia microsperma and Tinospora cordifolia are reported.     

Antimicrobial activity of alkaloidal fraction from barks of Himatanthus lancifolius

The alkaloidal fraction from Himatanthus lancifolius barks demonstrated a broad-spectrum in vitro antimicrobial activity for most of the Gram (+) and Gram (-) tested microorganisms.     

Antimicrobial activity of Hedychium spicatum

Extracts from rhizomes of Hedychium spicatum were tested for their antibacterial and antifungal activity. Essential oil, petroleum ether and chloroform extracts showed inhibitory activity against Gram (+) and Gram (-) bacterial cultures, including a strain of methicillin and vancomycin resistant Staphylococcus aureus and fungal cultures.     

Hepatoprotective activity of the Leucas lavandulaefolia on D(+)galactosamine-induced hepatic injury in rats

The chloroform extract of Leucas lavandulaefolia at an oral dose of 200 mg/kg and 400 mg/kg exhibited a significant protection on D(+)galactosamine induced liver damage in rats. Silymarin (25 mg/kg), a known hepatoprotective drug used as a standard also exhibited a significant activity.     

Antimicrobial activity of 2-arylbenzofurans from Morus species against methicillin-resistant Staphylococcus aureus

Nine 2-arylbenzofurans isolated from Morus species were tested for their antimicrobial activities against methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Among these compounds, chalcomoracin (a leaf phytoalexine of mulberry tree) exhibited considerable antibacterial activity against MRSAs (MICs 0.78 μg/ml).     

Antimicrobial properties of Uvaria chamae stem bark

The antimicrobial properties of the methanol extract of Uvaria chamae stembark (ME) were investigated. The more active ethylacetate-soluble fraction (EAS) was separated by PTLC into 18 sub-fractions. Following phytochemical and antimicrobial screening, several sub-fractions, testing positive for the presence of glycosides (8, 11–15) and tannins (18), exhibited activity against a number of microorganisms, being in some cases more active than penicillin G and chloramphenicol.     

Antimicrobial activity of Bryum argenteum

The antimicrobial activity of Bryum argenteum ethanol extracts was evaluated by microdilution method against four bacterial (Escherichia coli, Bacillus subtilis, Micrococcus luteus and Staphilococcus aureus) and four fungal species (Aspergillus niger, Penicillium ochrochloron, Candida albicans and Trichophyton mentagrophyes). All the investigated ethanol extracts have been proved to be active against all bacteria and fungi tested.     

Antimicrobial activity of Andrographis paniculata

The antimicrobial activity of aqueous extract, andrographolides and arabinogalactan proteins from Andrographis paniculata were evaluated. The aqueous extract showed significant antimicrobial activity, which may be due to the combined effect of the isolated arabinogalactan proteins and andrographolides.     

Antimicrobial activity of Diospyros anisandra

Leaves, root and stem bark of Diospyros anisandra were screened against two strains of Mycobacterium tuberculosis, one resistant and one susceptible to antibiotics, using the microplate Alamar blue assay test. The lypophylic fractions of the root and bark showed significant inhibitory activity against both strains, with the hexane fraction of the bark showing the strongest activity (MIC 6.25 microg/ml) against the resistant strain and a significant antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Candida albicans, Aspergillus niger, and Colletotrichum gloeosporioides. The bioassay-guided purification of the bioactive hexane fraction resulted in the isolation and identification of the naphthoquinone plumbagin as one of the metabolites responsible for the biological activity.     

Antimicrobial and free radical scavenging activity of Gentianella nitida

The antimicrobial and free radical scavenging activity of the ethanol extract and fractions of Gentianella nitida have been assessed. The most susceptible microorganisms were Candida albicans, Trichophyton mentagrophytes and Microsporum gypseum. The antifungal activity was concentrated in the 90% methanol and nonsoluble fractions, while the radical scavenging activity was stronger in the ethyl acetate and nonsoluble fractions.     

Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate

10-Isobutyryloxy-8,9-epoxythymol isobutyrate was found to be a major constituent of Inula helenium and Inula royleana root cultures. The compound showed moderate antimicrobial activity against Staphylococcus aureus, Enterococcus faecalis, Escherischia coli, Pseudomonas aeruginosa and Candida albicans.     

Antimicrobial activity and constituents of Coccoloba acrostichoides

The ethanol extract and fractions from Coccoloba acrostichoides aerial parts were assayed for in vitro antimicrobial activity. The extract was active against the assayed bacteria while most of the fractions also inhibited fungal growth, especially the n-hexane and EtOAc fractions. The isolated beta-sitosterol and betulin were tested, being the last one active against Fusarium oxysporum.     

Antimicrobial activity of extractives of Solidago microglossa

The antimicrobial activity of the methanol extract from Solidago microglossa roots, essential oil from its aerial part and some isolated compounds was investigated. The oil exhibited concentration-dependent activity against all the tested bacteria and yeasts.