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Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study—A Randomized Clinical Trial
Authors:A. Boswood  J. Häggström  S.G. Gordon  G. Wess  R.L. Stepien  M.A. Oyama  B.W. Keene  J. Bonagura  K.A. MacDonald  M. Patteson  S. Smith  P.R. Fox  K. Sanderson  R. Woolley  V. Szatmári  P. Menaut  W.M. Church  M. L. O'Sullivan  J.‐P. Jaudon  J.‐G. Kresken  J. Rush  K.A. Barrett  S.L. Rosenthal  A.B. Saunders  I. Ljungvall  M. Deinert  E. Bomassi  A.H. Estrada  M.J. Fernandez Del Palacio  N.S. Moise  J.A. Abbott  Y. Fujii  A. Spier  M.W. Luethy  R.A. Santilli  M. Uechi  A. Tidholm  P. Watson
Affiliation:1. Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, UK;2. Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE;3. Small Animal Clinical Science, Texas A&M University, College Station, TX;4. Clinic of Small Animal Medicine, University of Munich, Munich, Germany;5. Medical Sciences, University of Wisconsin Madison School of Veterinary Medicine, Madison, WI;6. Clinical Studies‐Philadelphia, MJR‐VHUP‐Cardiology, University of Pennsylvania, Philadelphia, PA;7. Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC;8. Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH;9. Animal Care Center, Rohnert Park, CA;10. HeartVets @ Vale Referrals, The Animal Hospital, Dursley, Gloucestershire, UK;11. Sarah Smith Cardiology, Derby, UK;12. Animal Medical Center, New York, NY;13. Rocky Mountain Veterinary Cardiology, Boulder, CO;14. Cardio Respiratory Pet Referrals Victoria, Mordialloc, Vic, Australia;15. Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, Utrecht, Netherlands;16. Internal Medicine and Cardiology, Clinique Vétérinaire Aquivet, Eysines, France;17. Desert Veterinary Medical Specialists, Phoenix, AZ;18. Deptartment of Clinical Studies, University of Guelph, Ontario Veterinary College, Guelph, ON, Canada;19. Clinique Veterinaire Des Etangs, Villars Les Dombes, France;20. Clinic for Small Animals Kaiserberg, Duisburg, Germany;21. Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton, MA;22. Cardiology, VCA West Los Angeles, Los Angeles, CA;23. Cardiac Care for Pets, Towson, MD;24. Tierklinik am Sandpfad, Wiesloch, Germany;25. Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux, France;26. Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL;27. Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia, Spain;28. Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY;29. Department of Small Animal Clinical Sciences, Virginia Tech, Virginia‐Maryland College of Veterinary Medicine, Blacksburg, VA;30. Azabu University, Chuo‐ku, Sagamihara, Kanagawa, Japan;31. Blue Pearl Veterinary Partners, Tampa, FL;32. Chicago Veterinary Emergency and Specialty Center, Chicago, IL;33. Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese, Italy;34. JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama, Japan;35. Djursjukhuset Albano, Danderyd, Sweden;36. Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany
Abstract:
Keywords:Asymptomatic  Echocardiography  Endocardiosis  Heart failure  Mitral regurgitation  Prevention  Treatment  Vertebral heart sum
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