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Failure to Detect Soluble Tumor Associated Antigen by Radioimmunoassay in Bovine Lymphoma |
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| Authors: | R.M. Jacobs V.E.O. Valli B.N. Wilkie |
| Abstract: | The detection of circulating soluble tumor-associated antigen by radioimmunoassay was attempted in cows with lymphoma. The assay system did detect PAGE-purified tumor-associated antigen but did not detect immunoreactive substances in the sera of 20 affected animals and 20 normal cattle. Similarly, ultrafiltration of low pH-dissociated serum to separate immune complexes did not aid in the detection of antigen. |
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