Epistatic effects between pairs of the growth hormone secretagogue receptor 1a,growth hormone,growth hormone receptor,non‐SMC condensin I complex,subunit G and stearoyl‐CoA desaturase genes on carcass,price‐related and fatty acid composition traits in Japanese Black cattle |
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| Authors: | Masanori Komatsu Kagetomo Nishino Yoshito Aihara Hisato Takeda Hideaki Takahashi |
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| Affiliation: | 1. Institute of Livestock and Grassland Science, National Agriculture and Food, Research Organization (NARO), Tsukuba, Ibaraki, Japan;2. Komatsu Laboratory of Computational Biology for Domestic Animals, Ryugasaki, Ibaraki, JapanThese authors contributed equally to the work.;3. Ibaraki Prefecture Livestock Research Centre, Ibaraki, Japan |
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| Abstract: | Growth hormone secretagogue receptor 1a (GHSR1a), growth hormone (GH), growth hormone receptor (GHR), non‐SMC condensin I complex, subunit G (NCAPG) and stearoyl‐CoA desaturase (SCD), are known to play important roles in growth and lipid metabolisms. Single and epistatic effects of the five genes on carcass, price‐related and fatty acid (FA) composition traits were analyzed in a commercial Japanese Black cattle population of Ibaraki Prefecture. A total of 650 steers and 116 heifers for carcass and price‐related traits, and 158 steers for FA composition traits were used in this study. Epistatic effects between pairs of the five genes were found in several traits. Alleles showing strain‐specific differences in the five genes had significant single and epistatic effects in some traits. The data suggest that a TG‐repeat polymorphism of the GHSR1a.5′UTR‐(TG)n locus plays a central role in gene–gene epistatic interaction of FA composition traits in the adipose tissue of Japanese Black cattle. |
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| Keywords: | carcass and fatty acids traits epistasis GHSR1a/GH/GHR Japanese Black cattle
NCAPG
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