| 感染鸭源小鹅瘟病毒QH-L01株樱桃谷雏鸭病理学研究 |
| |
| 引用本文： | 陈兵,徐婧,罗启慧,黄超,刘文涛,吴洪,陈镜妃,陈苹,高琪,马文静,陈正礼. 感染鸭源小鹅瘟病毒QH-L01株樱桃谷雏鸭病理学研究[J]. 浙江农业学报, 2018, 30(6): 932. DOI: 10.3969/j.issn.1004-1524.2018.06.07 |
| |
| 作者姓名： | 陈兵 徐婧 罗启慧 黄超 刘文涛 吴洪 陈镜妃 陈苹 高琪 马文静 陈正礼 |
| |
| 作者单位： | 1.四川农业大学 动物医学院,实验动物疾病模型实验室,四川 成都 611130; 2.四川农业大学 动物疫病与人类健康四川省重点实验室,四川 成都 611130 |
| |
| 基金项目： | 国家科技支撑计划(2014BAI03B01); 国家重大科学仪器设备开发专项(2013YQ49085906) |
| |
| 摘 要： | 探究人工感染条件下,鸭源小鹅瘟病毒QH-L01株对樱桃谷雏鸭各器官组织病理学变化的影响,以期阐明QH-L01的病理发生规律及特征。实验组以每只0.2 mL(106.54 ELD50)的剂量肌肉接种30只2日龄樱桃谷肉鸭鸭源小鹅瘟病毒,对照组的鸭接种等量的灭菌生理盐水,分别在1、3、6、9 d观察各组织器官的病理变化。感染后1 d,先出现肺点状出血,部分肺小叶扩张,十二指肠、回肠和盲肠等肠道组织绒毛上皮细胞坏死脱落。感染后3 d,脑、肾、胸腺、法氏囊出现病理变化,十二指肠、回肠和盲肠等肠道组织绒毛和黏膜层轻度坏死、脱落。感染后6 d,脾脏淋巴细胞增多,十二指肠、回肠和盲肠等肠道组织绒毛和黏膜层中度坏死、脱落。感染后9 d,各组织病变减轻或者恢复正常。整个感染期死亡率为20%。
|
| 关 键 词： | 鸭源小鹅瘟病毒 樱桃谷肉鸭 病理变化 损伤 |
| 收稿时间： | 2017-09-25 |
Pathological study on duck-origin goose Parvovirus strain QH-L01 infection of Cherry Valley duck |
| |
| CHEN Bing,XU Jing,LUO Qihui,HUANG Chao,LIU Wentao,WU Hong,CHEN Jingfei,CHEN Ping,GAO Qi,MA Wenjing,CHEN Zhengli. Pathological study on duck-origin goose Parvovirus strain QH-L01 infection of Cherry Valley duck[J]. Acta Agriculturae Zhejiangensis, 2018, 30(6): 932. DOI: 10.3969/j.issn.1004-1524.2018.06.07 |
| |
| Authors: | CHEN Bing XU Jing LUO Qihui HUANG Chao LIU Wentao WU Hong CHEN Jingfei CHEN Ping GAO Qi MA Wenjing CHEN Zhengli |
| |
| Affiliation: | 1. Laboratory of Animal Disease Model, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China;
2. Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China |
| |
| Abstract: | In the present study, the histopathological changes of various organs of Cherry Valley ducklings were explored under the condition of artificial infection, to clarify the pathogenesis and characteristics of duck-origin goose Parvovirus strain QH-L01. Thirty Cherry Valley ducks in experimental group were intramuscularly inoculated with 0.2 mL of 106.54 ELD50 duck-origin goose Parvovirus strain, and the ducks in the control group were intramuscularly inoculated with 0.2 mL of sterilized normal saline per duck, to observe the pathological changes of various tissues/organs in each infective stage at 1, 3, 6, 9 d, respectively. On the 1st day after infection, the lungs appeared punctate hemorrhage, partial lobular expansion, and intestinal tissue villous epithelial cells necrosed. On the 3rd day after infection, brain, kidney, thymus, bursa fabricius showed pathological changes, and villus of duodenum and ileum slight necrosed, mucosa layer of cecum appeared slight necrosis. On the 6th day after infection, lymphocytes in spleen increased, moderate necrosis was detected in villus of duodenum, ileum and mucosa layer of cecum. On the 9th day after infection, the lesions were reduced or returned to normal. The mortality rate was 20% during the whole infection period. |
| |
| Keywords: | duck-origin goose Parvovirus cherry valley duck pathological change damage |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《浙江农业学报》浏览原始摘要信息 |
|
点击此处可从《浙江农业学报》下载全文 |
|
